MP:0020422 (decreased freezing behavior) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: decreased freezing behavior

Definition

a decreased display, frequency, or duration of freezing behavior

Synonyms

decreased freezing behaviour

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 9

Gene / Allele	Zygosity	Life Stage	Phenotype	Parameter	Phenotyping Center	P Value
Upf3b Upf3b^em1(IMPC)Tcp	HOM	Early adult	decreased freezing behavior	Cue Baseline % Freezing Time Fear Conditioning	TCP IMPC	1.00×10^-08
Gria1 Gria1^em1(IMPC)H	HOM	Late adult	decreased freezing behavior	Cue Baseline % Freezing Time Fear Conditioning	MRC Harwell IMPC	1.04×10^-08
Setd3 Setd3^{tm1.1(NCOM)Mfgc}	HOM	Early adult	decreased freezing behavior	Conditioning Baseline % Freezing Time Fear Conditioning	TCP IMPC	1.36×10^-08
Cog5 Cog5^{em1(IMPC)Ccpcz}	HET	Early adult	decreased freezing behavior	Conditioning Baseline % Freezing Time Fear Conditioning	CCP-IMG IMPC	1.24×10^-07
Glrb Glrb^em1(IMPC)Tcp	HET	Early adult	decreased freezing behavior	Conditioning Baseline % Freezing Time Fear Conditioning	TCP IMPC	4.42×10^-06
Acot3 Acot3^em1(IMPC)Mbp	HOM	Early adult	decreased freezing behavior	Conditioning Baseline % Freezing Time Fear Conditioning	UC Davis IMPC	7.84×10^-06
Sgce Sgce^em1(IMPC)H	HOM	Late adult	decreased freezing behavior	Cue Baseline % Freezing Time Fear Conditioning	MRC Harwell IMPC	7.34×10^-05
Pdxdc1 Pdxdc1^em1(IMPC)Tcp	HOM	Early adult	decreased freezing behavior	Conditioning Baseline % Freezing Time Fear Conditioning	TCP IMPC	8.91×10^-05

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Procedure
Fear Conditioning

0.48% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased freezing behavior (8/1661)

0.13% females (2/1533) 0.30% males (5/1688)

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