How We Generate Our Data

  • Targeting genes that haven’t been studied yet
  • Standardised production methods to knock out genes
  • Mutants and wildtype mice tested under the same phenotyping protocols
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Understanding Our Data

  • We generate our own data, it is not aggregated from publications
  • A constantly growing dataset; mice continually tested
  • Data from 19 IMPC phenotyping centres, in 11 countries
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Animal Welfare

The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.

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Latest Data Release

Data release 10 has now been published. The number of phenotyped mutant lines has reached 6,255, bringing the total number of phenotyped genes to 5,861.

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About the IMPC Project

The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.

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We’re systematically phenotyping new knockout mice every day

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IMPC Strategy 2021-2030

The IMPC’s 10-year strategy presents a bold ambition for the future functional annotation of the genome and deciphering genetic variation in the context of gene function and disease.

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Research Reveals Novel Genetic Influences On Osteoporosis

With the help of IMPC resources, recent research published in Nature Genetics identifies novel genetic influences on osteoporosis, with the potential to empower future research on osteoporosis and potentially lead to new drug targets.

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Our Collaborations

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Maintaining and expanding a world-wide consortium of institutions

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