banner
Genes Phenotypes Help, News, Blog

Phenotype: increased CD8-positive, CD25-positive alpha-beta T cell number

Definition
increase in the number of CD8-positive alpha-beta T cells expressing the activation marker CD25
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased CD8-positive, CD25-positive alpha-beta T cell number

Total number of significant genotype-phenotype associations: 3

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Lgr5
Lgr5em1(IMPC)Kmpc 		HET Early adult increased CD8-positive, CD25-positive alpha-beta T cell number CD8 CD25+ T cells
Immunophenotyping		 KMPC
IMPC		 8.03×10-08
Btbd3
Btbd3tm1b(EUCOMM)Hmgu 		HOM Early adult increased CD8-positive, CD25-positive alpha-beta T cell number CD8 CD25+ T cells
Immunophenotyping		 CCP-IMG
IMPC		 5.54×10-06

Download data as:   TSV   XLS

 The way we measure

Procedure
Immunophenotyping
FACS

 Phenotype associations stats

2.70% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased CD8-positive, CD25-positive alpha-beta T cell number (2/74)

1.47% females (1/68) 3.03% males (2/66)



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter