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Phenotype: abnormal myeloid dendritic cell morphology

Definition
any structural anomaly of phagocytic cells of the myeloid lineage that capture antigens in the periphery and then migrate to the lymphoid organs and secrete cytokines to initiate immune responses
Synonyms
abnormal DC1 morphology
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal myeloid dendritic cell morphology

Total number of significant genotype-phenotype associations: 2

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Chd9
Chd9tm1a(EUCOMM)Wtsi 		HOM   Early adult increased Langerhans cell number Langerhans cell (LC) count
Ear epidermis immunophenotyping		 WTSI
3i		 0.00
Hbs1l
Hbs1ltm1a(KOMP)Wtsi 		HOM   Early adult decreased Langerhans cell number Langerhans cell (LC) count
Ear epidermis immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Ear epidermis immunophenotyping

 Phenotype associations stats

0.46% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal myeloid dendritic cell morphology (2/433)

0.00% females (0/2) 0.00% males (0/2)

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