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Phenotype: increased body size

Definition
larger than average body weight, height and/or length of an organism compared to controls
Synonyms
increased size,  large body size
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased body size

Total number of significant genotype-phenotype associations: 64

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Zfc3h1
Zfc3h1em1(IMPC)Mbp 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 UC Davis
IMPC		 1.40×10-45
Med28
Med28tm1.1(KOMP)Vlcg 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 UC Davis
IMPC		 3.38×10-30
Kptn
Kptntm1a(EUCOMM)Wtsi 		HOM Early adult increased body weight Body Weight
Heart Dissection		 WTSI
MGP		 6.77×10-14
Ebf4
Ebf4em1(IMPC)Bay 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 8.05×10-11
Trnt1
Trnt1tm1a(EUCOMM)Hmgu 		HET Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 9.36×10-11
Rnd2
Rnd2em1(IMPC)Mbp 		HOM Late adult increased body length Body length
Body Composition (DEXA lean/fat)		 UC Davis
IMPC		 5.27×10-10
Ndufaf6
Ndufaf6tm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 5.35×10-10
Lingo2
Lingo2em1(IMPC)Kmpc 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 KMPC
IMPC		 4.59×10-09
Uso1
Uso1em1(IMPC)Bay 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 6.57×10-08
Hltf
Hltfem1(IMPC)Bay 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 1.28×10-07
Trpm6
Trpm6tm1b(KOMP)Wtsi 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 ICS
IMPC		 3.62×10-07
Limk2
Limk2tm1a(EUCOMM)Wtsi 		HET Early adult increased body length Body length
DEXA		 ICS
EuroPhenome		 3.65×10-07
Ecrg4
Ecrg4tm1b(EUCOMM)Hmgu 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 ICS
IMPC		 4.45×10-07
Nhp2
Nhp2tm1a(KOMP)Wtsi 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 4.95×10-07
Ppp1r1a
Ppp1r1aem2(IMPC)Marc 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 MARC
IMPC		 1.02×10-06
Fgfr4
Fgfr4tm1b(EUCOMM)Wtsi 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 1.09×10-06
Mob1a
Mob1aem1(IMPC)Bay 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 1.36×10-06
Cdh1
Cdh1tm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 WTSI
EuroPhenome		 1.43×10-06
Ppp3ca
Ppp3catm2e(EUCOMM)Wtsi 		HOM Early adult increased body weight Body Weight
Heart Dissection		 WTSI
MGP		 2.12×10-06
Lyz3
Lyz3tm1(KOMP)Vlcg 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 UC Davis
IMPC		 2.47×10-06
Tmem132b
Tmem132bem1(IMPC)Ccpcz 		HOM Early adult increased body weight Weight
Lung mechanics by forced oscillations		 CCP-IMG
IMPC		 3.15×10-06
Rtbdn
Rtbdntm1a(EUCOMM)Wtsi 		HET Early adult increased body length Body Length
Dexa-scan analysis		 WTSI
MGP		 3.33×10-06
Dis3l2
Dis3l2em1(IMPC)Bay 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 3.92×10-06
Adprs
Adprsem1(IMPC)Wtsi 		HOM   Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 5.42×10-06
Arhgap18
Arhgap18tm1a(KOMP)Wtsi 		HOM Early adult increased body length Body Length
Dexa-scan analysis		 WTSI
MGP		 6.92×10-06
Trim8
Trim8em1(IMPC)Wtsi 		HOM   Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 8.46×10-06
Drg2
Drg2tm1a(EUCOMM)Wtsi 		HET Early adult increased body length Body length
DEXA		 ICS
EuroPhenome		 9.07×10-06
Acot8
Acot8em1(IMPC)Bay 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 1.22×10-05
Acbd5
Acbd5tm1b(EUCOMM)Wtsi 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 1.25×10-05
Kdm8
Kdm8tm1a(EUCOMM)Wtsi 		HET   Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 1.57×10-05
Prss53
Prss53em3(IMPC)Wtsi 		HOM   Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 1.75×10-05
Lta4h
Lta4hem2(IMPC)Wtsi 		HOM   Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 1.87×10-05
Pnpla1
Pnpla1tm1b(KOMP)Wtsi 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 ICS
IMPC		 2.13×10-05
Foxp2
Foxp2tm2.1Woen 		HET Early adult increased body weight Body weight
Spontaneous breathing (GMC)		 HMGU
EuroPhenome		 2.18×10-05
Magi2
Magi2tm1Grnt 		HET Early adult increased body weight Body Weight
Body Weight		 WTSI
MGP		 2.19×10-05
Zhx3
Zhx3tm1.1(KOMP)Vlcg 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 UC Davis
IMPC		 2.62×10-05
Spn
Spnem1(IMPC)Ics 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 ICS
IMPC		 2.64×10-05
Bpnt2
Bpnt2tm1a(KOMP)Wtsi 		HET   Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 2.67×10-05
Snap29
Snap29tm1a(EUCOMM)Wtsi 		HET Early adult increased body length Body Length
Dexa-scan analysis		 WTSI
MGP		 2.74×10-05
Lrrc3
Lrrc3tm1b(EUCOMM)Hmgu 		HOM   Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 ICS
IMPC		 2.81×10-05
Hsf2bp
Hsf2bptm1a(EUCOMM)Hmgu 		HOM Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 2.98×10-05
Mfsd2b
Mfsd2btm1a(KOMP)Wtsi 		HOM   Early adult increased body length Body Length
Dexa-scan analysis		 WTSI
MGP		 3.30×10-05
Hdac11
Hdac11em1(IMPC)Kmpc 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 KMPC
IMPC		 3.48×10-05
Cpgi5563
Cpgi5563tm1.1(NCC)WCS 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 3.59×10-05
Etl4
Etl4em1(IMPC)Bay 		HOM   Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 3.94×10-05
Mta3
Mta3tm3a(KOMP)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 WTSI
EuroPhenome		 4.63×10-05
Kdm4b
Kdm4btm1a(EUCOMM)Wtsi 		HET   Early adult increased body length Body Length
Dexa-scan analysis		 WTSI
MGP		 4.89×10-05
Ankrd9
Ankrd9tm1(KOMP)Wtsi 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 WTSI
IMPC		 4.97×10-05
Sdhc
Sdhctm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Heart Dissection		 WTSI
MGP		 5.11×10-05
4931422A03Rik
4931422A03Riktm1b(EUCOMM)Wtsi 		HOM Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 5.13×10-05
Frmd5
Frmd5tm1a(EUCOMM)Hmgu 		HOM Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 5.81×10-05
Xbp1
Xbp1tm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 5.98×10-05
Acat2
Acat2tm1b(KOMP)Wtsi 		HET   Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 BCM
IMPC		 6.20×10-05
Sqstm1
Sqstm1tm1a(KOMP)Wtsi 		HOM Early adult increased body length Body Length
Dexa-scan analysis		 WTSI
MGP		 6.48×10-05
Irx6
Irx6tm1b(KOMP)Mbp 		HOM Late adult increased body length Body length
Body Composition (DEXA lean/fat)		 KMPC
IMPC		 7.62×10-05
Mfrp
Mfrptm1a(KOMP)Wtsi 		HOM   Early adult increased body weight Body Weight
Hot Plate		 WTSI
MGP		 8.80×10-05
Rnf31
Rnf31tm1b(KOMP)Wtsi 		HET Early adult increased body length Body length
Body Composition (DEXA lean/fat)		 UC Davis
IMPC		 8.87×10-05
Fahd2a
Fahd2atm1a(EUCOMM)Wtsi 		HOM   Early adult increased body length Body Length
Dexa-scan analysis		 WTSI
MGP		 9.99×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Body Composition (DEXA lean/fat)
Grip Strength
Heart Weight
Indirect Calorimetry
Organ Weight
Acoustic Startle&PPI
Age monitoring
Auditory Brain Stem Response
Body Weight
Bodyweight (GMC)
Challenge Whole Body Plethysmography
Clickbox
Clinical Blood Chemistry
DEXA
Dexa-scan analysis
Dysmorphology
ERG (Electroretinogram) (GMC)
Eye size (GMC)
Fasted Bleed
Food efficiency (GMC)
Grip Strength (GMC)
Grip-Strength
Heart Dissection
Heart weight/tibia length
Holeboard (GMC)
Hot Plate
IPGTT
Indirect ophthalmoscopy
Insulin Blood Level
Insulin t=0
Intraperitoneal glucose tolerance test (IPGTT)
Lung mechanics by forced oscillations
Non-Invasive blood pressure
Rotarod
Rotarod B (GMC)
SHIRPA
Shirpa (GMC)
Simplified IPGTT
Spontaneous breathing (GMC)
Terminal Bleed

 Phenotype associations stats

1.06% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased body size (58/5482)

0.50% females (27/5440) 0.44% males (24/5435)

Select a parameter    



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