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Phenotype: abnormal cardiac stroke volume

Definition
anomaly in the volume of blood pushed into the aorta with each beat of the heart
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal cardiac stroke volume

Total number of significant genotype-phenotype associations: 20

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Fnip1
Fnip1em1(IMPC)Ccpcz 		HOM Early adult increased cardiac stroke volume Stroke Volume
Echo		 CCP-IMG
IMPC		 5.81×10-23
Xrcc5
Xrcc5em1(IMPC)Ccpcz 		HOM Early adult decreased cardiac stroke volume Stroke Volume
Echo		 CCP-IMG
IMPC		 6.99×10-13
Hells
Hellstm1b(EUCOMM)Wtsi 		HET Early adult increased cardiac stroke volume Stroke Volume
Echo		 HMGU
IMPC		 3.98×10-11
Psd3
Psd3em1(IMPC)H 		HOM Late adult increased cardiac stroke volume Stroke Volume
Echo		 MRC Harwell
IMPC		 1.81×10-10
Grem2
Grem2em1(IMPC)Bay 		HET Early adult increased cardiac stroke volume Stroke Volume
Echo		 BCM
IMPC		 4.81×10-10
Nek1
Nek1em1(IMPC)Bay 		HOM Early adult decreased cardiac stroke volume Stroke Volume
Echo		 BCM
IMPC		 1.53×10-06
Pla2g2e
Pla2g2etm1b(EUCOMM)Wtsi 		HOM Early adult increased cardiac stroke volume Stroke Volume
Echo		 HMGU
IMPC		 2.42×10-06
Kcng2
Kcng2em1(IMPC)Bay 		HOM Early adult decreased cardiac stroke volume Stroke Volume
Echo		 BCM
IMPC		 2.44×10-06
Lep
Leptm1b(EUCOMM)Hmgu 		HOM   Early adult increased cardiac stroke volume Stroke Volume
Echo		 BCM
IMPC		 2.59×10-06
Gdf11
Gdf11tm2b(EUCOMM)Hmgu 		HET Early adult increased cardiac stroke volume Stroke Volume
Echo		 BCM
IMPC		 2.93×10-06
Mdc1
Mdc1em1(IMPC)Bay 		HOM Late adult decreased cardiac stroke volume Stroke Volume
Echo		 BCM
IMPC		 3.18×10-06
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi 		HOM   Early adult decreased cardiac stroke volume Stroke Volume
Echo		 BCM
IMPC		 4.31×10-06
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu 		HET Early adult decreased cardiac stroke volume Stroke Volume
Echo		 HMGU
IMPC		 5.29×10-06
Fam53b
Fam53btm1b(EUCOMM)Hmgu 		HOM Early adult increased cardiac stroke volume Stroke Volume
Echo		 HMGU
IMPC		 1.27×10-05
Hycc1
Hycc1em1(IMPC)Ccpcz 		HOM Early adult increased cardiac stroke volume Stroke Volume
Echo		 CCP-IMG
IMPC		 3.47×10-05
Pdgfc
Pdgfctm1b(EUCOMM)Hmgu 		HET   Late adult increased cardiac stroke volume Stroke Volume
Echo		 HMGU
IMPC		 7.48×10-05
Mgat1
Mgat1tm1b(EUCOMM)Hmgu 		HET Early adult decreased cardiac stroke volume Stroke Volume
Echo		 HMGU
IMPC		 8.68×10-05
Rsad2
Rsad2em1(IMPC)H 		HOM   Late adult increased cardiac stroke volume Stroke Volume
Echo		 MRC Harwell
IMPC		 9.33×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.95% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal cardiac stroke volume (18/1899)

0.32% females (6/1883) 0.63% males (10/1600)

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