Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Cacng8 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Autism, Susceptibility To, 20 | Attention deficit hyperactivity disorder, Reduced social reciprocity | OMIM:618830 | |
Childhood Disintegrative Disorder | Abnormal emotion, Mental deterioration, Progressive language deterioration, Reduced social recipr... | ORPHA:168782 | |
Childhood Absence Epilepsy | Depression, Attention deficit hyperactivity disorder, Abnormal social behavior | ORPHA:64280 | |
Early-Onset Autosomal Dominant Alzheimer Disease | Abnormal social behavior, Memory impairment, Confusion, Semantic dementia, Dementia | ORPHA:1020 | |
Progressive Supranuclear Palsy | Abnormal synaptic transmission | ORPHA:683 |
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