banner
Genes Phenotypes Help, News, Blog

Gene: Mast4 MGI:1918885

Log in to follow
Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
microtubule associated serine/threonine kinase family member 4
Synonyms:
4930420O11Rik

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Mast4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Mast4 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Malocclusion Due To Protuberant Upper Front Teeth
Dental malocclusion OMIM:154300
Amelogenesis Imperfecta, Type Iiia
Amelogenesis imperfecta, Dental malocclusion, Anterior open-bite malocclusion OMIM:130900
Diastema, Dental Medial
Diastema, Widely-spaced maxillary central incisors OMIM:125900
Malposition Of Teeth With Or Without Hypodontia/Oligodontia
Hypodontia, Tooth malposition OMIM:189490
Amelogenesis Imperfecta, Hypomaturation Type, Iia6
Amelogenesis imperfecta, Anterior open-bite malocclusion, Enamel hypomineralization OMIM:617217
Incisors, Rotation Of Upper Central
Rotated maxillary central incisors OMIM:147350
Dentinogenesis Imperfecta, Shields Type Iii
Anterior open-bite malocclusion, Periapical bone loss, Dentinogenesis imperfecta, Dental enamel p... OMIM:125500
Amelogenesis Imperfecta, Hypomaturation Type, Iia1
Amelogenesis imperfecta, Yellow-brown discoloration of the teeth, Anterior open-bite malocclusion... OMIM:204700
Amelogenesis Imperfecta, Hypomaturation Type, Iia2
Amelogenesis imperfecta, Yellow-brown discoloration of the teeth, Anterior open-bite malocclusion... OMIM:612529
Amelogenesis Imperfecta, Type Iiic
Amelogenesis imperfecta, Yellow-brown discoloration of the teeth, Anterior open-bite malocclusion... OMIM:618386
Primary Condylar Hyperplasia
Anterior open-bite malocclusion, Macrodontia, Abnormality of the temporomandibular joint, Abnorma... ORPHA:477781
Cleft Palate, Isolated
Increased overbite, Anterior open-bite malocclusion, Gingival overgrowth, Micrognathia, Cleft palate OMIM:119540
Amelogenesis Imperfecta, Type Ic
Amelogenesis imperfecta, Yellow-brown discoloration of the teeth, Anterior open-bite malocclusion... OMIM:204650
Amelogenesis Imperfecta, Type Ih
Amelogenesis imperfecta, Yellow-brown discoloration of the teeth, Anterior open-bite malocclusion... OMIM:616221
Amelogenesis Imperfecta, Type Ie
Amelogenesis imperfecta, Enamel hypoplasia, Anterior open-bite malocclusion, Abnormal dentin morp... OMIM:301200
Hemifacial Hyperplasia
Hypoplasia of the maxilla, Dental malocclusion OMIM:133900
Amelogenesis Imperfecta, Type Iiib
Amelogenesis imperfecta, Enamel hypomineralization OMIM:617607
Amelogenesis Imperfecta, Hypoplastic/Hypomaturation, X-Linked 2
Amelogenesis imperfecta OMIM:301201
Amelogenesis Imperfecta, Type Ib
Amelogenesis imperfecta OMIM:104500
Amelogenesis Imperfecta, Hypomaturation Type, Iia3
Amelogenesis imperfecta, Hypomature dental enamel, Enamel hypomineralization OMIM:613211
Amelogenesis Imperfecta
Fragile teeth, Widely spaced teeth, Abnormal permanent molar morphology, Yellow-brown discolorati... ORPHA:88661
Dentin Dysplasia, Type Ii
Dentinogenesis imperfecta limited to primary teeth, Pulp calcification, Thistle tube shaped pulp OMIM:125420
Dentin Dysplasia, Type I
Oligodontia, Short dental root, Microdontia, Enamel hypoplasia, Periapical bone loss, Pulp oblite... OMIM:125400
Amelogenesis Imperfecta, Type Ij
Amelogenesis imperfecta, Widely spaced teeth, Increased overbite, Abnormal dentin morphology, Car... OMIM:617297
Carabelli Anomaly Of Maxillary Molar Teeth
Shovel-shaped maxillary central incisors, Abnormality of the dentition, Abnormality of molar OMIM:114700
Oligodontia
Short dental root, Microdontia, Eclabion, Agenesis of maxillary lateral incisor, Taurodontia, Age... ORPHA:99798
Van Der Woude Syndrome 2
Cleft upper lip, Cleft palate, Anodontia, Hypodontia, Dental malocclusion, Lip pit OMIM:606713
Amelogenesis Imperfecta, Hypomaturation Type, Iia4
Amelogenesis imperfecta, Enamel hypoplasia, Enamel hypomineralization OMIM:614832
Incisors, Shovel-Shaped
Shovel-shaped maxillary central incisors OMIM:147400
Amelogenesis Imperfecta, Type Ik
Amelogenesis imperfecta, Enamel hypoplasia OMIM:620104
Florid Cemento-Osseous Dysplasia
Supernumerary tooth, Atrophy of alveolar ridges, Oral ulcer, Abnormality of primary teeth, Abnorm... ORPHA:83451
Amelogenesis Imperfecta, Type Ia
Amelogenesis imperfecta, Enamel hypoplasia, Generalized microdontia, Dental enamel pits, Taurodontia OMIM:104530
Tooth Agenesis, Selective, 7
Agenesis of permanent teeth, Taurodontia OMIM:616724
Fused Mandibular Incisors
Advanced eruption of teeth, Abnormality of the dentition ORPHA:2287
Regional Odontodysplasia
Yellow-brown discoloration of the teeth, Eruption failure, Abnormality of primary teeth, Short de... ORPHA:83450
Amelogenesis Imperfecta, Type If
Amelogenesis imperfecta, Enamel hypoplasia, Dental enamel pits, Abnormality of dental color OMIM:616270
Intellectual Developmental Disorder, X-Linked 58
Dental malocclusion, Short philtrum OMIM:300210
Amelogenesis Imperfecta, Hypomaturation Type, Iia5
Amelogenesis imperfecta, Yellow-brown discoloration of the teeth, Carious teeth OMIM:615887
Dental Ankylosis
Abnormal dental enamel morphology, Mandibular prognathia, Tooth agenesis ORPHA:1077
Amelogenesis Imperfecta, Type Iv
Amelogenesis imperfecta, Yellow-brown discoloration of the teeth, Enamel hypoplasia, Taurodontia OMIM:104510
Taurodontism
Taurodontia OMIM:272700
Failure Of Tooth Eruption, Primary
Hypodontia, Failure of eruption of permanent teeth, Persistence of primary teeth OMIM:125350
Tooth Agenesis, Selective, 9
Selective tooth agenesis, Microdontia, Taurodontia OMIM:617275
Dentinogenesis Imperfecta 1
Yellow-brown discoloration of the teeth, Dentinogenesis imperfecta OMIM:125490
Gigantiform Cementoma, Familial
Multiple impacted teeth, Cementoma, Tooth malposition OMIM:137575
Teeth Present At Birth
Natal tooth OMIM:187050
Intestinal Pseudoobstruction With Patent Ductus Arteriosus And Natal Teeth
Natal tooth OMIM:243185
Cleft Lip/Palate
Orofacial cleft, Abnormal number of permanent teeth, Palate fistula, Bilateral cleft palate, Peg-... ORPHA:199306
Impacted Teeth, Multiple
Supernumerary tooth, Multiple impacted teeth OMIM:308280
Auriculocondylar Syndrome 2A
Short mandibular rami, Dental crowding, Mandibular condyle hypoplasia, Temporomandibular joint an... OMIM:614669
Hemifacial Atrophy, Progressive
Short mandibular rami, Dental malocclusion, Tongue atrophy, Delayed eruption of teeth OMIM:141300
Maxillonasal Dysplasia, Binder Type
Dental malocclusion OMIM:155050
Gingival Fibromatosis-Progressive Deafness Syndrome
Gingival overgrowth, Gingival fibromatosis, Delayed eruption of teeth ORPHA:2027
Auriculocondylar Syndrome 1
Anterior open-bite malocclusion, Dental crowding, Mandibular condyle hypoplasia, Glossoptosis, Na... OMIM:602483
Retinal Dystrophy, Juvenile Cataracts, And Short Stature Syndrome
Dental malocclusion, Widely spaced teeth, Malar flattening OMIM:616108
Non-Eruption Of Teeth-Maxillary Hypoplasia-Genu Valgum Syndrome
Delayed eruption of teeth, Maxillozygomatic hypoplasia, Abnormal dental morphology, Malar flatten... ORPHA:2972
Splenogonadal Fusion With Limb Defects And Micrognathia
Crowded maxillary incisors, Micrognathia, Multiple unerupted teeth OMIM:183300
Ackerman Syndrome
Broad philtrum, Taurodontia OMIM:200970
Steroid Dehydrogenase Deficiency-Dental Anomalies Syndrome
Abnormal dental enamel morphology, Enamel hypoplasia, Supernumerary tooth ORPHA:3196
Trichothiodystrophy 9, Nonphotosensitive
High, narrow palate, Dental malocclusion OMIM:619692
Dentin Dysplasia
Abnormal dental morphology, Abnormal dental enamel morphology ORPHA:1653
Neurodevelopmental Disorder With Impaired Intellectual Development, Hypotonia, And Ataxia
Mandibular prognathia, High palate, Dental malocclusion OMIM:618292
Skeletal Dysplasia-Epilepsy-Short Stature Syndrome
Mandibular prognathia, Abnormality of the dentition, Dental malocclusion ORPHA:1858
Dentin Dysplasia With Sclerotic Bones
Dentinogenesis imperfecta limited to primary teeth, Abnormality of the dentition OMIM:125440
Otodental Dysplasia
Agenesis of premolar, Delayed eruption of teeth, Enamel hypoplasia, Long philtrum, Tooth ankylosi... OMIM:166750
Steatocystoma Multiplex
Natal tooth OMIM:184500
Mcdonough Syndrome
Abnormal palate morphology, Short philtrum, Mandibular prognathia, Open bite, Micrognathia, Denta... ORPHA:2471
Rubinstein-Taybi Syndrome 2
Narrow palate, Retrognathia, Increased overbite, High palate, Talon cusp, Carious teeth, Microgna... OMIM:613684
Craniosynostosis 3
Dental malocclusion OMIM:615314
Odontotrichoungual-Digital-Palmar Syndrome
Mandibular prognathia, Natal tooth, Thick vermilion border, Dental malocclusion OMIM:601957
Dentinogenesis Imperfecta
Fragile teeth, Grayish enamel, Yellow-brown discoloration of the teeth, Selective tooth agenesis,... ORPHA:49042
Myasthenic Syndrome, Congenital, 4C, Associated With Acetylcholine Receptor Deficiency
Mandibular prognathia, High palate, Dental malocclusion OMIM:608931
Ankyloglossia With Or Without Tooth Anomalies
Supernumerary tooth, Ankyloglossia OMIM:106280
Alpha-Mannosidosis
Narrow palate, Widely spaced teeth, Craniofacial hyperostosis, Gingival overgrowth, Open bite, Ma... ORPHA:61
Intellectual Disability And Myopathy Syndrome
Dental malocclusion, Incisor macrodontia, Thin upper lip vermilion, Widely-spaced maxillary centr... OMIM:619719
Intellectual Developmental Disorder, Autosomal Recessive 39
Dental malocclusion OMIM:615541
Shaheen Syndrome
Enamel hypoplasia, Carious teeth OMIM:615328
Endosteal Hyperostosis, Autosomal Dominant
Dental malocclusion, Torus palatinus OMIM:144750
Potocki-Lupski Syndrome
Dental crowding, Mandibular prognathia, High palate, Micrognathia, Wide mouth, Smooth philtrum, D... OMIM:610883
Central Incisors, Absence Of
Agenesis of central incisor OMIM:302400
Mulibrey Nanism
Absent frontal sinuses, Dental crowding, Hypoplastic frontal sinuses, Enamel hypoplasia, Microglo... OMIM:253250
Retinitis Pigmentosa-Juvenile Cataract-Short Stature-Intellectual Disability Syndrome
Micrognathia, Diastema, Malar flattening, Dental malocclusion ORPHA:436245
Auriculocondylar Syndrome
Abnormality of the temporomandibular joint, Dental crowding, Mandibular condyle hypoplasia, Gloss... ORPHA:137888
Camptodactyly Syndrome, Guadalajara Type 1
Mandibular prognathia, Open bite, High palate, Narrow mouth, Downturned corners of mouth, Dental ... ORPHA:1327
Intermediate Osteopetrosis
Abnormal dental morphology, Dental malocclusion, Osteosclerosis of the base of the skull, Abnorma... ORPHA:210110
Cherubism
Narrow palate, Oligodontia, Jaw swelling, Dental malocclusion, Multiple impacted teeth, Alveolar ... OMIM:118400
Beaulieu-Boycott-Innes Syndrome
Carious teeth, Velopharyngeal insufficiency, Micrognathia, Dental malocclusion OMIM:613680
Oculodentodigital Dysplasia, Autosomal Recessive
Thin vermilion border, Hypoplasia of the primary teeth, Delayed eruption of teeth, Dental crowdin... OMIM:257850
Ehlers-Danlos Syndrome, Spondylodysplastic Type, 3
Delayed eruption of teeth, High palate, Bifid uvula, Hypodontia, Dental malocclusion OMIM:612350
Amelo-Onycho-Hypohidrotic Syndrome
Advanced eruption of teeth, Delayed eruption of teeth, Yellow-brown discoloration of the teeth, A... ORPHA:1028
Robinow Syndrome, Autosomal Dominant 2
Calvarial osteosclerosis, Triangular mouth, Cleft soft palate, Dental crowding, Oligodontia, Ging... OMIM:616331
Rutherfurd Syndrome
Failure of eruption of permanent teeth, Delayed eruption of primary teeth OMIM:180900
Otodental Syndrome
Agenesis of premolar, Abnormality of canine, Delayed eruption of teeth, Periodontitis, Abnormal d... ORPHA:2791
Momo Syndrome
Thick lower lip vermilion, Delayed eruption of teeth, High palate, Smooth philtrum, Long philtrum... OMIM:157980
Blepharophimosis-Impaired Intellectual Development Syndrome
Widely spaced teeth, Short philtrum, Exaggerated cupid's bow, Microdontia, Enamel hypoplasia, Wid... OMIM:619293
Lessel-Kreienkamp Syndrome
Dental malocclusion, Thin upper lip vermilion, Open mouth OMIM:619149
Deafness-Intellectual Disability Syndrome, Martin-Probst Type
Thick lower lip vermilion, Abnormality of the dentition, Everted lower lip vermilion, Micrognathi... ORPHA:85321
Mandibulofacial Dysostosis With Ptosis, Autosomal Dominant
Micrognathia, Malar flattening, Dental malocclusion OMIM:608257
Ectodermal Dysplasia With Facial Dysmorphism And Acral, Ocular, And Brain Anomalies
Conical tooth, Oligodontia, Microdontia, Persistence of primary teeth, Enamel hypoplasia, Malar f... OMIM:618727
Muenke Syndrome
Dental malocclusion, High palate, Malar flattening OMIM:602849
Acrootoocular Syndrome
Supernumerary tooth, Grayish enamel, High, narrow palate, Dental malocclusion, Delayed eruption o... ORPHA:2980
Pycnodysostosis
Obtuse angle of mandible, High palate, Abnormality of the dentition, Persistence of primary teeth... ORPHA:763
Three M Syndrome 2
Delayed eruption of teeth, High palate, Thick vermilion border, Malar flattening, Long philtrum, ... OMIM:612921
Zimmermann-Laband Syndrome
Supernumerary tooth, Gingival fibromatosis, Anterior open-bite malocclusion, High palate, Microgn... ORPHA:3473
Intellectual Disability, Buenos-Aires Type
Mandibular prognathia, Open bite, High palate, Abnormal dental morphology, Dental malocclusion ORPHA:3079
Myopathy, Myofibrillar, 8
Micrognathia, High palate, Dental malocclusion OMIM:617258
Fanconi Anemia, Complementation Group S
Narrow palate, Thick upper lip vermilion, Macrodontia, Dental malocclusion OMIM:617883
Thoc6-Related Developmental Delay-Microcephaly-Facial Dysmorphism Syndrome
Retrognathia, Thin lower lip vermilion, Abnormality of the dentition, Carious teeth, Thick upper ... ORPHA:363444
Momo Syndrome
Thick lower lip vermilion, Delayed eruption of teeth, High palate, Thick upper lip vermilion, Smo... ORPHA:2563
Larsen-Like Syndrome
Dental malocclusion, Cleft palate, Malar flattening OMIM:608545
Short Stature, Facial Dysmorphism, And Skeletal Anomalies With Or Without Cardiac Anomalies 1
Anterior open-bite malocclusion, Dental crowding, High palate, Everted lower lip vermilion, Pierr... OMIM:617877
Trichorhinophalangeal Syndrome, Type I
Narrow palate, Delayed eruption of teeth, Microdontia, Carious teeth, Micrognathia, Deep philtrum... OMIM:190350
Seckel Syndrome 1
Dental crowding, Selective tooth agenesis, High palate, Enamel hypoplasia, Micrognathia, Cleft pa... OMIM:210600
Congenital Muscular Dystrophy With Intellectual Disability And Severe Epilepsy
High palate, Micrognathia, Dental malocclusion, Deep philtrum, Thin upper lip vermilion ORPHA:329178
Satb2-Associated Syndrome Due To A Chromosomal Rearrangement
Short philtrum, Dental crowding, High palate, Abnormality of the dentition, Microdontia, Narrow m... ORPHA:251028
Otofaciocervical Syndrome 2, With T-Cell Deficiency
Carious teeth, Dental malocclusion, Microretrognathia OMIM:615560
Cri-Du-Chat Syndrome
Orofacial cleft, Thick lower lip vermilion, Short philtrum, Anterior open-bite malocclusion, High... OMIM:123450
Myopathy, Centronuclear, X-Linked
Dental malocclusion, High palate OMIM:310400
Harrod Syndrome
Narrow mouth, Dental malocclusion, High palate ORPHA:2115
Short Syndrome
Delayed eruption of teeth, Downturned corners of mouth, Micrognathia, Hypodontia, Dental malocclu... OMIM:269880
Hamamy Syndrome
Hypodontia, High palate, Everted lower lip vermilion, Enamel hypoplasia, Micrognathia, Wide mouth... OMIM:611174
Congenital Myopathy 17
Mandibular prognathia, High palate, Cleft palate, Tented upper lip vermilion, Smooth philtrum, Na... OMIM:618975
Kabuki Syndrome 2
High palate, Micrognathia, Cleft palate, Natal tooth, Hypodontia, Lower lip pit, Dental malocclusion OMIM:300867
Progeria-Short Stature-Pigmented Nevi Syndrome
Fragile teeth, Selective tooth agenesis, Micrognathia, Bifid uvula, Hypodontia, Dental malocclusion ORPHA:2959
Van Maldergem Syndrome 1
High palate, Irregular dentition, Hypoplasia of the maxilla, Downturned corners of mouth, Microgn... OMIM:601390
Takenouchi-Kosaki Syndrome
Widely spaced teeth, Short philtrum, Downturned corners of mouth, Wide mouth, Smooth philtrum, Lo... OMIM:616737
Barber-Say Syndrome
Thin vermilion border, Widely spaced teeth, Delayed eruption of teeth, Gingival overgrowth, Mandi... OMIM:209885
Frontometaphyseal Dysplasia 1
Delayed eruption of teeth, Absent frontal sinuses, Selective tooth agenesis, High palate, Persist... OMIM:305620
Hallermann-Streiff Syndrome
Narrow palate, Thin vermilion border, Supernumerary tooth, High, narrow palate, Selective tooth a... OMIM:234100
Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis
Anterior open-bite malocclusion ORPHA:83601
Sclerosteosis 1
Tooth malposition, Mandibular prognathia, Malar flattening, Facial palsy secondary to cranial hyp... OMIM:269500
Elsahy-Waters Syndrome
Agenesis of incisor, Supernumerary tooth, Thick lower lip vermilion, Delayed eruption of teeth, M... OMIM:211380
Noonan Syndrome 4
Dental malocclusion, Wide mouth, Thick vermilion border OMIM:610733
Van Maldergem Syndrome 2
High palate, Irregular dentition, Hypoplasia of the maxilla, Downturned corners of mouth, Microgn... OMIM:615546
Phelan-Mcdermid Syndrome
Widely spaced teeth, High palate, Micrognathia, Malar flattening, Long philtrum, Dental malocclusion OMIM:606232
Martin-Probst Syndrome
Thick lower lip vermilion, Micrognathia, Wide mouth, Malar flattening, Dental malocclusion OMIM:300519
Oliver Syndrome
Mandibular prognathia, High palate, Short philtrum, Dental malocclusion ORPHA:2920
Robinow Syndrome, Autosomal Dominant 3
Triangular mouth, Dental malocclusion, Gingival overgrowth, Downturned corners of mouth, Cleft pa... OMIM:616894
Cardiofaciocutaneous Syndrome 1
Open bite, High palate, Abnormality of the dentition, Submucous cleft hard palate, Micrognathia, ... OMIM:115150
Localized Scleroderma
Abnormal facial skeleton morphology, Abnormality of the dentition, Short dental root, Dental malo... ORPHA:90289
Osteopathia Striata With Cranial Sclerosis
Thick lower lip vermilion, Dental malocclusion, Dental crowding, High palate, Paranasal sinus hyp... OMIM:300373
Robinow Syndrome
Orofacial cleft, Triangular mouth, Tooth malposition, Hypodontia, Broad alveolar ridges, Dental c... ORPHA:97360
Acrodysostosis 1 With Or Without Hormone Resistance
Delayed eruption of teeth, Mandibular prognathia, Hypoplasia of the maxilla, Hypodontia, Dental m... OMIM:101800
Cerebellar-Facial-Dental Syndrome
Micrognathia, Long philtrum, Dental malocclusion, Macrodontia of permanent maxillary central inci... ORPHA:444072
Nestor-Guillermo Progeria Syndrome
Thin vermilion border, Dental malocclusion, Dental crowding, Micrognathia, Microretrognathia, Man... OMIM:614008
Cerebellofaciodental Syndrome
Dental malocclusion, Macrodontia of permanent maxillary central incisor, Taurodontia OMIM:616202
Faciocardiomelic Syndrome
Micrognathia, Wide mouth, Long philtrum, Dental malocclusion, Hyperplasia of the maxilla OMIM:612731
Shprintzen-Goldberg Craniosynostosis Syndrome
Narrow palate, High palate, Hypoplasia of the maxilla, Micrognathia, Dental malocclusion OMIM:182212
7Q11.23 Microduplication Syndrome
Thin vermilion border, Retrognathia, Short philtrum, Short lingual frenulum, High palate, Microgn... ORPHA:96121
Au-Kline Syndrome
Retrognathia, Oligodontia, High palate, Downturned corners of mouth, Bifid uvula, Cleft palate, O... OMIM:616580
Apert Syndrome
Narrow palate, Delayed eruption of teeth, Mandibular prognathia, Bifid uvula, Cleft palate, Malar... OMIM:101200
Bosma Arhinia Microphthalmia Syndrome
Dental malocclusion, High palate, Hypoplasia of teeth, Paranasal sinus hypoplasia, Cleft palate, ... OMIM:603457
Neurodevelopmental Disorder-Craniofacial Dysmorphism-Cardiac Defect-Skeletal Anomalies Syndrome Due To A Point Mutation
High, narrow palate, Abnormality of primary teeth, Open bite, Exaggerated cupid's bow, Exaggerate... ORPHA:453504
Neurodevelopmental Disorder-Craniofacial Dysmorphism-Cardiac Defect-Skeletal Anomalies Syndrome Due To 9Q21.3 Microdeletion
High, narrow palate, Abnormality of primary teeth, Open bite, Exaggerated cupid's bow, Exaggerate... ORPHA:352665
Multiple Pterygium Syndrome, Escobar Variant
Triangular mouth, High palate, Narrow mouth, Downturned corners of mouth, Cleft palate, Micrognat... OMIM:265000
Schwartz-Jampel Syndrome
Supernumerary tooth, Narrow mouth, Everted lower lip vermilion, High palate, Micrognathia, Cleft ... ORPHA:800
Turnpenny-Fry Syndrome
Hypoplasia of the primary teeth, Widely spaced teeth, Dental crowding, Mandibular prognathia, Hig... OMIM:618371
Macrothrombocytopenia-Lymphedema-Developmental Delay-Facial Dysmorphism-Camptodactyly Syndrome
Widely spaced teeth, Short philtrum, Downturned corners of mouth, Wide mouth, Tented upper lip ve... ORPHA:487796
Spondyloenchondrodysplasia
Dental malocclusion, Delayed eruption of teeth ORPHA:1855
Faciodigitogenital Syndrome, Autosomal Recessive
Narrow palate, High palate, Wide mouth, Trismus, Dental malocclusion, Deep philtrum OMIM:227330
Holoprosencephaly 9
Agenesis of incisor, Thick lower lip vermilion, Solitary median maxillary central incisor, Short ... OMIM:610829
Hajdu-Cheney Syndrome
Absent frontal sinuses, Premature loss of teeth, High palate, Narrow mouth, Micrognathia, Malar f... OMIM:102500
Frank-Ter Haar Syndrome
Broad alveolar ridges, Gingival overgrowth, High palate, Micrognathia, Wide mouth, Dental maloccl... OMIM:249420
Traboulsi Syndrome
Retrognathia, High palate, Bifid uvula, Malar flattening, Dental malocclusion OMIM:601552
Osteopetrosis, Autosomal Recessive 3
Dental malocclusion OMIM:259730
Global Developmental Delay-Osteopenia-Ectodermal Defect Syndrome
Thin vermilion border, Conical incisor, Maxillary lateral incisor microdontia, Micrognathia, Long... ORPHA:73223
Cockayne Syndrome A
Mandibular prognathia, Hypoplasia of teeth, Carious teeth, Enamel hypoplasia, Dental malocclusion... OMIM:216400
Cockayne Syndrome B
Mandibular prognathia, Hypoplasia of teeth, Carious teeth, Dental malocclusion, Delayed eruption ... OMIM:133540
Mccune-Albright Syndrome
Dental malocclusion, Abnormal facial skeleton morphology ORPHA:562
Rubinstein-Taybi Syndrome 1
Narrow palate, Retrognathia, High, narrow palate, Dental crowding, Narrow mouth, Talon cusp, High... OMIM:180849
Microphthalmia, Syndromic 2
Supernumerary tooth, Radiculomegaly, Dental malocclusion, Delayed eruption of teeth, Oligodontia,... OMIM:300166
Craniosynostosis And Dental Anomalies
Narrow palate, Supernumerary tooth, Delayed eruption of teeth, Dental crowding, Mandibular progna... OMIM:614188
Spondylometaphyseal Dysplasia With Cone-Rod Dystrophy
Dental malocclusion OMIM:608940
Cockayne Syndrome
Abnormal dental morphology, Enamel hypoplasia, Carious teeth, Dental malocclusion, Agenesis of pe... ORPHA:191
Osteogenesis Imperfecta
Delayed eruption of teeth, Abnormality of dental color, Abnormal dental enamel morphology, Abnorm... ORPHA:666
Coffin-Lowry Syndrome
Narrow palate, Thick lower lip vermilion, Widely spaced teeth, Mandibular prognathia, High palate... OMIM:303600
Rubinstein-Taybi Syndrome Due To 16P13.3 Microdeletion
Narrow palate, Supernumerary tooth, Dental crowding, Talon cusp, Carious teeth, Natal tooth, Hypo... ORPHA:353281
Rubinstein-Taybi Syndrome Due To Ep300 Haploinsufficiency
Narrow palate, Supernumerary tooth, Dental crowding, High palate, Talon cusp, Carious teeth, Micr... ORPHA:353284
Rubinstein-Taybi Syndrome Due To Crebbp Mutations
Narrow palate, Supernumerary tooth, Dental crowding, High palate, Talon cusp, Carious teeth, Micr... ORPHA:353277
Carpenter Syndrome 2
Narrow palate, Retrognathia, High, narrow palate, High palate, Carious teeth, Long philtrum, Dent... OMIM:614976
Williams Syndrome
Thick lower lip vermilion, Dental malocclusion, Hypodontia, Abnormal dental enamel morphology, Gi... ORPHA:904
Monosomy 22Q13.3
Dental crowding, Dental malocclusion, Malar flattening ORPHA:48652
Focal Dermal Hypoplasia
Delayed eruption of teeth, Oligodontia, Enamel hypoplasia, Cleft upper lip, Cleft palate, Hypodon... OMIM:305600
Aneurysm-Osteoarthritis Syndrome
Retrognathia, High palate, Bifid uvula, Cleft palate, Malar flattening, Dental malocclusion ORPHA:284984
Fraser Syndrome 1
Dental crowding, Dental malocclusion, Cleft palate, Cleft upper lip OMIM:219000
Noonan Syndrome 1
High, narrow palate, High palate, Micrognathia, Cleft palate, Dental malocclusion OMIM:163950
Fraser Syndrome
Orofacial cleft, Dental crowding, High palate, Cleft upper lip, Dental malocclusion, Bifid tongue ORPHA:2052
Simpson-Golabi-Behmel Syndrome, Type 1
Narrow palate, Gingival overgrowth, Mandibular prognathia, Exaggerated median tongue furrow, Clef... OMIM:312870
Williams-Beuren Syndrome
Thick lower lip vermilion, Hypodontia, Microdontia, Malar flattening, Open mouth, Long philtrum, ... OMIM:194050
Loeys-Dietz Syndrome 3
Retrognathia, High palate, Bifid uvula, Cleft palate, Malar flattening, Dental malocclusion OMIM:613795

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Mast4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Mast4.

No publications found that use IMPC mice or data for Mast4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter