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Genes Phenotypes Help, News, Blog

Gene: Kcng1 MGI:3616086

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Gene Summary

Name:
potassium voltage-gated channel, subfamily G, member 1
Synonyms:
OTTMUSG00000016048

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retina blood vessel morphology Kcng1em1(IMPC)Tcp HOM   Early adult 4.24×10-07
abnormal lens morphology Kcng1em1(IMPC)Tcp HOM Early adult 3.62×10-09
cataract Kcng1em1(IMPC)Tcp HOM Early adult 3.36×10-09
decreased prepulse inhibition Kcng1em1(IMPC)Tcp HOM Early adult 9.59×10-12
abnormal retina vasculature morphology Kcng1em1(IMPC)Tcp HOM   Early adult 4.16×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Eye Morphology

Images Ophthalmoscopy

113 Images

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Eye Morphology

Images Slit Lamp

108 Images

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X-ray

XRay Images Skull Dorso Ventral Orientation

9 Images

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Gross Pathology and Tissue Collection

Images

8 Images

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X-ray

XRay Images Whole Body Lateral Orientation

9 Images

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X-ray

XRay Images Skull Lateral Orientation

9 Images

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X-ray

XRay Images Whole Body Dorso Ventral

9 Images

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Electrocardiogram (ECG)

Waveform Image

1 Images

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Human diseases caused by Kcng1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.
No human diseases associated to this gene by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Kcng1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Kcng1.

No publications found that use IMPC mice or data for Kcng1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Kcng1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Kcng1tm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells
Kcng1em1(IMPC)Tcp Exon Deletion Mice
Kcng1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells

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