All nervous system phenotype, behavior/neurological phenotype data for Cdk5rap3

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status Graph
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery resting time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.090140 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center permanence time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.22705 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Whole arena resting time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.11774 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Activity (body position) HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Head bobbing HET 8f:14m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb grip strength normalised against body weight HET 2f:9m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_GRS_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Trunk curl HET 8f:14m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Locomotor activity HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.10989 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center resting time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.17333 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Eye Morphology / Optic Disc HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center average speed HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.69197 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Contact righting HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HET 1f:7m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_GRS_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Distance travelled - total HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.22447 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Number of rears - total HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.26582 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.25035 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery permanence time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.22733 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Gait HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.17919 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.73732 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Indirect Calorimetry / Total food intake HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0053420 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Latency to center entry HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.050587 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Percentage center time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.22705 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Aggression HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Number of center entries HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.13740 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Tremor HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.40229 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.011006 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb grip strength measurement mean HET 2f:9m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_GRS_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Startle response HET 8f:14m Fisher Exact Test framework 1.0000 Not tested (No variation) - OK
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery average speed HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.093013 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.45535 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Limb grasp HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Eye Morphology / Pupil Light Response HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Whole arena average speed HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.11093 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Rotarod / Latency to fall_Mean HET 2f:6m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'HMGU_ROT_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center distance travelled HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.19676 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Vocalization HET 8f:14m Fisher Exact Test framework 1.0000 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery distance travelled HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.87778 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 1f:7m Not processed 1.0000 FAILED - Not enough data points in dependent variable 'IMPC_GRS_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.

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