All nervous system phenotype, behavior/neurological phenotype data for Cdk5rap3

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery resting time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0901 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center permanence time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.227 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Whole arena resting time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.118 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Activity (body position) HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Head bobbing HET 8f:14m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb grip strength normalised against body weight HET 2f:9m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Trunk curl HET 8f:14m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Locomotor activity HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.110 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center resting time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.173 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Eye Morphology / Optic Disc HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center average speed HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.692 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Contact righting HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HET 1f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Distance travelled - total HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.224 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Number of rears - total HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.266 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Unexpected behaviors HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.250 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery permanence time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.227 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Gait HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.179 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.737 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Indirect Calorimetry / Total food intake HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00534 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Latency to center entry HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0506 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Percentage center time HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.227 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Aggression HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Number of center entries HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.137 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Tremor HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.402 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0110 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb grip strength measurement mean HET 2f:9m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Startle response HET 8f:14m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery average speed HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0930 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.455 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Limb grasp HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Eye Morphology / Pupil Light Response HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Whole arena average speed HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.111 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Rotarod / Latency to fall_Mean HET 2f:6m Not processed 1.00 FAILED - Not enough data points in dependent variable 'HMGU_ROT_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Center distance travelled HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.197 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Combined SHIRPA and Dysmorphology / Vocalization HET 8f:14m Fisher Exact Test framework 1.00 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Open Field / Periphery distance travelled HET 8f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.878 Success
Cdk5rap3tm1b(EUCOMM)Hmgu HMGU Grip Strength / Forelimb and hindlimb grip strength measurement mean HET 1f:7m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.

Download data as: TSV XLS

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