Definition
greater number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions
Synonyms
increased CD8-positive T cell number,
increased CD8+ T cell number
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased CD8-positive, alpha-beta T cell number
Total number of significant genotype-phenotype associations: 58
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta memory T cell number | CD8+ CD44+ CD62L- alpha beta effector T cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1+ CD8 alpha-beta T cell number | KLRG1+ CD8+ T cells - % of CD8+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta memory T cell number | CD8+ CD44+ CD62L- alpha beta effector T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1+ CD8 alpha-beta T cell number | KLRG1+ CD8+ T cells - % of CD8+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Cxcr2 Cxcr2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1+ CD8 alpha-beta T cell number | KLRG1+ CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Cxcr2 Cxcr2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cxcr2 Cxcr2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta memory T cell number | CD8+ CD44+ CD62L- alpha beta effector T cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| D6Wsu163e D6Wsu163etm1b(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Dbn1 Dbn1tm1b(KOMP)Wtsi |
HET | Early adult | increased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD8+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | CD8+ alpha beta T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Hbs1l Hbs1ltm1a(KOMP)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Nrbp1 Nrbp1tm3b(EUCOMM)Wtsi |
HET | Early adult | increased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Pepd Pepdtm1a(KOMP)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD8+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Sgsm1 Sgsm1tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | increased KLRG1+ CD8 alpha-beta T cell number | KLRG1+ CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem127 Tmem127tm1(KOMP)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Psmb11 Psmb11em1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
4.84×10-26 | |
| Klk10 Klk10em1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.10×10-20 | |
| Card11 Card11em1(IMPC)Ccpcz |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.13×10-17 | |
| Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | CD8 CD44+CD62L+ T cells Immunophenotyping |
ICS IMPC |
2.39×10-10 | |
| Ppp3cb Ppp3cbem1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
5.06×10-10 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | CD8 CD44+CD62L- T cells Immunophenotyping |
HMGU IMPC |
1.54×10-08 | |
| Krt1 Krt1em1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
6.52×10-08 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
HET | Early adult | increased CD8-positive, CD25-positive alpha-beta T cell number | CD8 CD25+ T cells Immunophenotyping |
KMPC IMPC |
8.03×10-08 | |
| Nxn Nxntm1b(EUCOMM)Wtsi |
HET | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.13×10-07 | |
| Parp1 Parp1tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | CD8 CD44+CD62L+ T cells Immunophenotyping |
ICS IMPC |
2.08×10-06 | |
| Btk Btktm1a(EUCOMM)Hmgu |
HEM | Early adult | increased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
ICS EuroPhenome |
2.48×10-06 | |
| Cd38 Cd38em1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
3.81×10-06 | |
| Nfkbid Nfkbidtm1a(EUCOMM)Wtsi |
HET | Early adult | increased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
HMGU EuroPhenome |
4.61×10-06 | |
| Btbd3 Btbd3tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased CD8-positive, CD25-positive alpha-beta T cell number | CD8 CD25+ T cells Immunophenotyping |
CCP-IMG IMPC |
5.54×10-06 | |
| Lhx1 Lhx1tm1e(EUCOMM)Wtsi |
HET | Early adult | increased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
ICS EuroPhenome |
6.38×10-06 | |
| Dcaf5 Dcaf5em1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
7.96×10-06 | |
| B4galnt3 B4galnt3tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
ICS EuroPhenome |
1.19×10-05 | |
| Hells Hellstm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
HMGU EuroPhenome |
2.29×10-05 | |
| Tnfrsf1a Tnfrsf1aem1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.46×10-05 | |
| Klhl6 Klhl6em1(IMPC)Ccpcz |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.83×10-05 | |
| Spred1 Spred1em1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
4.22×10-05 | |
| Spata31f3 Spata31f3em1(IMPC)Ccpcz |
HOM | Early adult | increased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
4.74×10-05 | |
| Apbb1ip Apbb1ipem1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
6.29×10-05 | |
| Cpm Cpmem1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
6.64×10-05 | |
| Pank2 Pank2em1(IMPC)Ccpcz |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
7.06×10-05 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | CD8 CD44+CD62L+ T cells Immunophenotyping |
CCP-IMG IMPC |
8.38×10-05 | |
| Ube3c Ube3ctm1b(EUCOMM)Hmgu |
HOM | Early adult | increased effector memory CD8-positive, alpha-beta T cell number | CD8 CD44+CD62L+ T cells Immunophenotyping |
HMGU IMPC |
8.44×10-05 |