IMPRESS is built on the concept of a “phenotype pipeline”: a sequence of individual procedures performed on a mouse at a specified age and organized to minimize interference from one procedure to the next. All IMPRESS pipelines are available here.
The IMPC Pipeline is a core set of procedures and parameters to be collected by all phenotyping centers. It contains procedures that are done at various stages in mouse development, including the embryonic stage.
Centres may also develop their own pipelines, including one or more additional Procedures specific to that centre. For example, Harwell-specific procedure Organ Weight [HRWL_OWT_001] inherits all the Procedures of the IMPC Pipeline Heart Weight [IMPC_HWT_001] and augments it with some custom ones like Spleen weight and others. Many centre-specific procedures do not have an IMPC equivalent and are special to a centre. Some centres do similar procedures but under different conditions and so these tests are considered seperate.
Pipeline identifier and versioning
Pipelines have unique identifiers as well as a number that indicates their version. The IMPC_001 key identifier indicates it is version 1 of IMPC Pipeline. Procedures and Parameters native to that Pipeline will have the prefix of the pipeline identifier present in their key as well. For example, Procedure IMPC_XRY_001 is version 1 of the X-ray Procedure from the IMPC Pipeline (though it does not indicate which version of the IMPC Pipeline).