I see some phenotypic terms that are associated to more than one biological system; why does this happen?
This is dictated by the ontology.
Some associations are quite obvious:
- For example, the phenotype term “short tibia” is a “limbs/digits/tail” as well as a “skeleton” phenotype (e.g., Aak1)
There are other associations that might be less obvious:
- The phenotype term “abnormal optic disk morphology” is a “nervous system” and a “vision/eye” phenotype (e.g., Cant1)
- The phenotype term “abnormal retinal vasculature morphology” is a “cardiovascular system” and a “vision/eye” phenotype (e.g., Cant1)
For this reason, when you select a biological system to use as a filter in the All Data table, you may find procedures that, at first glance, may not seem to be associated with the biological system you are filtering for. For example, if you are interested in behaviour phenotypes, you need to filter for “behaviour/neurological or nervous system” phenotypes, which will include startle reflex and limb grasping phenotypes, but also other less obvious phenotypes, such as vison/eye phenotypes, among others.
See the EMBL-EBI Ontology Lookup Service: