Showing 1751 to 1760 of 1817 entries
abnormal corpus callosum morphology
No IMPC genes are currently associated with this phenotype
Synonym:
corpus callosum dysplasia
Definition: any structural anomaly of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres
decreased dentate gyrus size
No IMPC genes are currently associated with this phenotype
Synonym:
reduced dentate gyrus size,
reduced dentate gyrus
Definition: reduced size of one of two interlocking gyri of the hippocampus formation that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus
abnormal KLRG1+ CD8 alpha-beta T cell number
No IMPC genes are currently associated with this phenotype
Synonym:
Definition: anomaly in the number of CD8+ alpha beta T cells that express KLRG1, a marker of effector and memory T cells
abnormal dendritic cell morphology
20 genes associated with this phenotype
Synonym:
Definition: any structural anomaly of a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation
abnormal ovary size
36 genes associated with this phenotype
Synonym:
Definition: anomaly in the average size of the female reproductive gland containing the germ cells
abnormal mature NK cell number
No IMPC genes are currently associated with this phenotype
Synonym:
Definition: anomaly in the number of NK cells expressing the maturation marker CD11b
increased basophil cell number
131 genes associated with this phenotype
Synonym:
increased basophil count,
high basophil count,
increased basophil number
Definition: higher than average number of basophils as measured by the percent of the total number of leukocytes
thin skin
2 genes associated with this phenotype
Synonym:
Definition: reduced thickness of the outer protective layer of the body
absent liver
1 gene associated with this phenotype
Synonym:
Definition: absence of the bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage
increased transitional stage T1 B cell number
1 gene associated with this phenotype
Synonym:
increased transitional one stage B-cell number,
increased T1 stage B cell number,
increased transitional one stage B lymphocyte number,
increased transitional one stage B-lymphocyte number
Definition: greater number of a type of transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen; this cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative
Showing 1751 to 1760 of 1817 entries