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Phenotype: decreased CD5-positive Ly6C-positive T cell number

Definition
reduction in the number of CD5-positive T cells expressing the memory marker Ly6C
Synonyms
reduced CD5-positive Ly6C-positive T cell number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased CD5-positive Ly6C-positive T cell number

Total number of significant genotype-phenotype associations: 4

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Ube3c
Ube3ctm1b(EUCOMM)Hmgu 		HOM Early adult decreased CD5-positive Ly6C-positive T cell number T Subset
Immunophenotyping		 HMGU
IMPC		 1.54×10-07
Nub1
Nub1tm1b(EUCOMM)Hmgu 		HOM Early adult decreased CD5-positive Ly6C-positive T cell number T Subset
Immunophenotyping		 CCP-IMG
IMPC		 6.49×10-06
Pepd
Pepdtm1b(KOMP)Wtsi 		HOM Late adult decreased CD5-positive Ly6C-positive T cell number T Subset
Immunophenotyping		 HMGU
IMPC		 3.14×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Immunophenotyping
FACS
Spleen Immunophenotyping

 Phenotype associations stats

4.41% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased CD5-positive Ly6C-positive T cell number (3/68)

1.59% females (1/63) 4.62% males (3/65)

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