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Phenotype: decreased memory-marker CD4-negative NK T cell number

Definition
reduction in the number of memory-marker CD4-negative NK T cells with a CD44+ CD62L- phenotype
Synonyms
reduced memory-marker CD4-negative NK T cell number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased memory-marker CD4-negative NK T cell number

Total number of significant genotype-phenotype associations: 9

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Clpp
Clpptm1a(EUCOMM)Wtsi 		HOM   Early adult decreased memory-marker CD4-negative NK T cell number Effector CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi 		HOM   Early adult decreased memory-marker CD4-negative NK T cell number Effector CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Gimap6
Gimap6tm1a(KOMP)Wtsi 		HOM   Early adult decreased memory-marker CD4-negative NK T cell number Effector CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Gmds
Gmdstm1a(KOMP)Wtsi 		HOM   Early adult decreased memory-marker CD4-negative NK T cell number Resting CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Hbs1l
Hbs1ltm1a(KOMP)Wtsi 		HOM   Early adult decreased memory-marker CD4-negative NK T cell number Effector CD4- NKT cells - % of CD4- NKT cells
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu 		HOM   Early adult decreased memory-marker CD4-negative NK T cell number Resting CD4- NKT cells - % of CD4- NKT cells
Spleen Immunophenotyping		 WTSI
3i		 0.00
Abcg8
Abcg8tm1b(KOMP)Wtsi 		HOM   Early adult decreased memory-marker CD4-negative NK T cell number DN CD44+CD62L- NKT cells
Immunophenotyping		 CCP-IMG
IMPC		 3.94×10-06
Nub1
Nub1tm1b(EUCOMM)Hmgu 		HOM Early adult decreased memory-marker CD4-negative NK T cell number DN CD44+CD62L- NKT cells
Immunophenotyping		 CCP-IMG
IMPC		 1.22×10-05
Bach2
Bach2tm1b(EUCOMM)Wtsi 		HOM Early adult decreased memory-marker CD4-negative NK T cell number DN CD44+CD62L- NKT cells
Immunophenotyping		 HMGU
IMPC		 2.16×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Immunophenotyping
FACS
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

 Phenotype associations stats

1.68% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased memory-marker CD4-negative NK T cell number (9/535)

1.22% females (1/82) 1.25% males (1/80)

Select a parameter    



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