Definition
reduction in the number of the naìˆve regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions with a CD44-low CD62L+ phenotype
Synonyms
reduced CD8-positive, naive alpha-beta T cell number
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased CD8-positive, naive alpha-beta T cell number
Total number of significant genotype-phenotype associations: 11
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | CD8 CD44-CD62L+ T cells Immunophenotyping |
HMGU IMPC |
3.64×10-08 | |
| Zc3h8 Zc3h8em1(IMPC)Ccpcz |
HET | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
4.09×10-06 | |
| Apbb1ip Apbb1ipem1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.34×10-05 | |
| Dcaf12 Dcaf12em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
3.57×10-05 | |
| Plag1 Plag1em1(IMPC)Hmgu |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | CD8 CD44-CD62L+ T cells Immunophenotyping |
HMGU IMPC |
4.74×10-05 | |
| Clock Clockem1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
6.02×10-05 | |
| Nwd2 Nwd2em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
6.57×10-05 |