Phenotype: increased cardiac stroke volume

Definition
increase in the volume of blood pushed into the aorta with each beat of the heart
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased cardiac stroke volume

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Hells
Hellstm1b(EUCOMM)Wtsi
HET Early adult increased cardiac stroke volume Stroke Volume
Echo
HMGU
IMPC
3.98×10-11
Grem2
Grem2em1(IMPC)Bay
HET Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
7.44×10-10
Gdf11
Gdf11tm2b(EUCOMM)Hmgu
HET Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
1.77×10-06
Pla2g2e
Pla2g2etm1b(EUCOMM)Wtsi
HOM Early adult increased cardiac stroke volume Stroke Volume
Echo
HMGU
IMPC
2.42×10-06
Lep
Leptm1b(EUCOMM)Hmgu
HOM   Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
2.59×10-06
Fam53b
Fam53btm1b(EUCOMM)Hmgu
HOM Early adult increased cardiac stroke volume Stroke Volume
Echo
HMGU
IMPC
1.27×10-05
Fam126a
Fam126aem1(IMPC)Ccpcz
HOM Early adult increased cardiac stroke volume Stroke Volume
Echo
CCP-IMG
IMPC
3.06×10-05
Mapkap1
Mapkap1tm1b(EUCOMM)Wtsi
HET Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
6.12×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.47% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased cardiac stroke volume (8/1700)

0.30% females (5/1680) 0.14% males (2/1405)



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