Phenotype: decreased heart left ventricle size

Definition
less than average size of the left ventricle compared to the average for a particular population
Synonyms
decreased left ventricle size,  reduced left ventricle size
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased heart left ventricle size

Total number of significant genotype-phenotype associations: 18

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Ints6l
Ints6lem1(IMPC)Marc
HEM   Early adult decreased heart left ventricle size LVPWs
Echo
MARC
IMPC
4.42×10-08
Ascc2
Ascc2tm1b(EUCOMM)Wtsi
HET Early adult decreased heart left ventricle size LVAWd
Echo
BCM
IMPC
1.05×10-06
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Late adult decreased heart left ventricle size LVAWd
Echo
ICS
IMPC
4.82×10-06
Abhd3
Abhd3em1(IMPC)Marc
HOM Early adult decreased heart left ventricle size LVPWs
Echo
MARC
IMPC
4.90×10-06
Ints6l
Ints6lem1(IMPC)Marc
HOM   Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
8.58×10-06
Gsdmd
Gsdmdem1(IMPC)Marc
HOM   Early adult decreased heart left ventricle size LVPWs
Echo
MARC
IMPC
9.94×10-06
Kdm2b
Kdm2bem1(IMPC)Marc
HET   Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
1.93×10-05
Trim37
Trim37em1(IMPC)Marc
HOM   Early adult decreased heart left ventricle size LVPWs
Echo
MARC
IMPC
1.96×10-05
Ube2z
Ube2zem1(IMPC)Marc
HET   Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
2.18×10-05
Prmt6
Prmt6em1(IMPC)Marc
HOM   Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
2.33×10-05
Vav2
Vav2em1(IMPC)Marc
HOM   Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
3.07×10-05
Phf21b
Phf21bem1(IMPC)Marc
HOM Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
3.09×10-05
Hilpda
Hilpdaem1(IMPC)Mhzh
HOM   Early adult decreased heart left ventricle size LVPWs
Echo
MARC
IMPC
5.46×10-05
Ccdc83
Ccdc83em1(IMPC)Marc
HOM   Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
5.91×10-05
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
HET   Early adult decreased heart left ventricle size LVAWd
Echo
MARC
IMPC
8.13×10-05
Emc4
Emc4tm1(KOMP)Wtsi
HET Early adult decreased heart left ventricle size LVPWs
Echo
MARC
IMPC
8.24×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.71% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart left ventricle size (15/2111)

0.19% females (4/2078) 0.17% males (3/1800)

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