Phenotype: increased heart left ventricle size

Definition
greater than average size of the left ventricle
Synonyms
enlarged left ventricle,  enlarged heart left ventricle
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased heart left ventricle size

Total number of significant genotype-phenotype associations: 15

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Apol10b
Apol10btm1b(KOMP)Wtsi
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 7.34×10-09
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM Early adult increased heart left ventricle size Echo | LVAWd MRC Harwell | IMPC 1.55×10-08
Slc10a2
Slc10a2tm1b(KOMP)Mbp
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 8.48×10-08
Gngt2
Gngt2em1(IMPC)Bay
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 1.64×10-07
Skil
Skiltm1b(EUCOMM)Hmgu
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 2.03×10-06
Fzd8
Fzd8em1(IMPC)Bay
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 2.35×10-06
Slc2a12
Slc2a12em2(IMPC)Bay
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 4.70×10-06
Erg
Ergem1(IMPC)Bay
HET Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 6.57×10-06
Mthfd2
Mthfd2tm1b(EUCOMM)Wtsi
HET Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 8.18×10-06
Arhgap24
Arhgap24tm1b(KOMP)Wtsi
HOM Early adult increased heart left ventricle size Echo | LVAWd ICS | IMPC 1.00×10-05
Map3k12
Map3k12tm1b(EUCOMM)Hmgu
HET Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 1.70×10-05
Atad5
Atad5em1(IMPC)Bay
HET Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 2.14×10-05
Rnf10
Rnf10em1(IMPC)Bay
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 2.45×10-05
Rnf19b
Rnf19bem1(IMPC)Ccpcz
HET Early adult increased heart left ventricle size Echo | LVAWd CCP-IMG | IMPC 7.99×10-05
Scn2b
Scn2bem1(IMPC)Bay
HOM Early adult increased heart left ventricle size Echo | LVAWd BCM | IMPC 8.61×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.15% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart left ventricle size (15/1307)

0.54% females (7/1288) 0.30% males (3/1013)



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