Phenotype: decreased heart rate

Definition
fewer than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute
Synonyms
bradycardia,  bradyrhythmia,  reduced heart rate
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased heart rate

Total number of significant genotype-phenotype associations: 226

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Pla2g10
Pla2g10tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
6.29×10-26
Mmaa
Mmaaem1(IMPC)J
HOM   Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
6.38×10-15
Hcn1
Hcn1em1(IMPC)H
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
3.05×10-14
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
3.52×10-14
Ndufa8
Ndufa8tm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
8.71×10-14
Trim55
Trim55tm2b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.35×10-13
Maged1
Maged1em1(IMPC)Mbp
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
2.43×10-13
Dmp1
Dmp1tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
6.77×10-12
Tmem203
Tmem203em1(IMPC)H
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
7.52×10-12
Mmaa
Mmaaem1(IMPC)J
HOM   Late adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
9.45×10-12
Six1
Six1em1(IMPC)Mbp
HET Late adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.28×10-10
Nfix
Nfixem6(IMPC)H
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
4.33×10-10
Slc6a6
Slc6a6em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
9.58×10-10
Maged1
Maged1em1(IMPC)Mbp
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.12×10-09
Psors1c2
Psors1c2em1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
1.30×10-09
Dmp1
Dmp1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.44×10-09
Mmab
Mmabem1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
2.76×10-09
Nadsyn1
Nadsyn1tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
5.40×10-09
Slc6a6
Slc6a6em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
6.12×10-09
Dennd5b
Dennd5bem1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
1.06×10-08
Nav1
Nav1em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.25×10-08
Rab4a
Rab4atm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.56×10-08
Pex1
Pex1tm1e.1(EUCOMM)Hmgu
HET Early adult decreased heart rate HR
Echo
HMGU
IMPC
2.52×10-08
Hcn1
Hcn1em1(IMPC)H
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.53×10-08
Trim55
Trim55tm2b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
3.18×10-08
Tfap4
Tfap4tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
3.95×10-08
Hipk3
Hipk3tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
4.49×10-08
Oplah
Oplahtm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Echo
HMGU
IMPC
5.09×10-08
Dpp8
Dpp8em1(IMPC)J
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
5.17×10-08
Cap2
Cap2tm1b(EUCOMM)Wtsi
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
8.90×10-08
Six1
Six1em1(IMPC)Mbp
HET Late adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.16×10-07
Zdhhc22
Zdhhc22em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.31×10-07
Try10
Try10em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.47×10-07
Tmem203
Tmem203em1(IMPC)H
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.60×10-07
Maged1
Maged1em1(IMPC)Mbp
HEM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.78×10-07
Tfap4
Tfap4tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.86×10-07
Lamtor3
Lamtor3em1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
1.89×10-07
Zbed6
Zbed6em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.93×10-07
Lcorl
Lcorlem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.96×10-07
Slfn1
Slfn1tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
2.11×10-07
Zfp280d
Zfp280dem1(IMPC)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
2.28×10-07
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
2.46×10-07
Nfix
Nfixem6(IMPC)H
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.56×10-07
Hcrt
Hcrttm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
2.76×10-07
Cpa5
Cpa5em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.80×10-07
Anapc7
Anapc7em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.82×10-07
Zfp280d
Zfp280dem1(IMPC)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
2.89×10-07
Spa17
Spa17em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.01×10-07
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
3.34×10-07
Smo
Smotm1b(KOMP)Wtsi
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
3.51×10-07
Anapc7
Anapc7em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.73×10-07
Uhrf2
Uhrf2tm1b(EUCOMM)Wtsi
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
4.13×10-07
Mindy2
Mindy2em1(IMPC)H
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
4.17×10-07
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Echo
BCM
IMPC
4.31×10-07
Tat
Tatem1(IMPC)J
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
4.38×10-07
Spa17
Spa17em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
5.10×10-07
Try10
Try10em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
5.10×10-07
Smo
Smotm1b(KOMP)Wtsi
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
6.13×10-07
Wars
Warstm1b(EUCOMM)Hmgu
HET Early adult decreased heart rate HR
Echo
HMGU
IMPC
6.14×10-07
Hells
Hellstm1b(EUCOMM)Wtsi
HET   Early adult decreased heart rate HR
Echo
HMGU
IMPC
6.42×10-07
Nadsyn1
Nadsyn1tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
6.66×10-07
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
7.40×10-07
Hipk3
Hipk3tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
7.94×10-07
Ndufa6
Ndufa6em1(IMPC)Bay
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
8.12×10-07
Bbox1
Bbox1tm1a(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
8.62×10-07
Lmtk2
Lmtk2em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
9.19×10-07
Gabre
Gabreem1(IMPC)H
HEM   Late adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.63×10-07
Smarcc2
Smarcc2em1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.01×10-06
Tnfrsf17
Tnfrsf17tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.03×10-06
Zbed6
Zbed6em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.12×10-06
Maged1
Maged1em1(IMPC)Mbp
HEM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.17×10-06
Nav1
Nav1em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.18×10-06
Dennd5b
Dennd5bem1(IMPC)Tcp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
1.25×10-06
Psors1c2
Psors1c2em1(IMPC)Hmgu
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
1.63×10-06
Cpa5
Cpa5em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.68×10-06
Smarcc2
Smarcc2em1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.84×10-06
Slfn1
Slfn1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.85×10-06
Prss55
Prss55em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
2.11×10-06
Rab4a
Rab4atm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.27×10-06
Zfp541
Zfp541em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.47×10-06
Gbp2
Gbp2tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
2.54×10-06
Bbox1
Bbox1tm1a(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.78×10-06
Mindy2
Mindy2em1(IMPC)H
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.79×10-06
Nutf2
Nutf2tm1b(KOMP)Mbp
HET Early adult decreased heart rate HR
Echo
HMGU
IMPC
2.89×10-06
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
2.92×10-06
Wsb2
Wsb2tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Echo
HMGU
IMPC
3.16×10-06
Efcab14
Efcab14tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Echo
BCM
IMPC
3.59×10-06
Dpp8
Dpp8em1(IMPC)J
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.59×10-06
Il18r1
Il18r1em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
3.75×10-06
Wbp1l
Wbp1ltm2b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
3.80×10-06
Insig2
Insig2em1(IMPC)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.61×10-06
Pla2g10
Pla2g10tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.91×10-06
Tmem62
Tmem62em1(IMPC)Ccpcz
HOM   Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
5.05×10-06
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
5.76×10-06
P4ha3
P4ha3em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
5.79×10-06
Vgf
Vgfem1(IMPC)H
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
6.57×10-06
Ndufa6
Ndufa6em1(IMPC)Bay
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
6.83×10-06
Uhrf2
Uhrf2tm1b(EUCOMM)Wtsi
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
6.84×10-06
Trh
Trhem1(IMPC)Tcp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
7.24×10-06
Dgkb
Dgkbem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
7.28×10-06
Brd3
Brd3em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
7.33×10-06
Tnfrsf17
Tnfrsf17tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
7.59×10-06
Ptpn18
Ptpn18em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
7.96×10-06
Got1
Got1tm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
8.31×10-06
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
9.44×10-06
Cenpt
Cenptem1(IMPC)Bay
HET   Late adult decreased heart rate HR
Echo
BCM
IMPC
9.51×10-06
Btnl4
Btnl4em1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
9.88×10-06
Efhb
Efhbem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.91×10-06
Lamtor3
Lamtor3em1(IMPC)Hmgu
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
1.00×10-05
Gabra2
Gabra2em1(IMPC)H
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.02×10-05
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.04×10-05
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.10×10-05
Pygm
Pygmem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.20×10-05
Ubl7
Ubl7em1(IMPC)Tcp
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
1.24×10-05
Il33
Il33tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.26×10-05
Pak2
Pak2em1(IMPC)H
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.32×10-05
P3h1
P3h1tm1b(EUCOMM)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.34×10-05
Myo6
Myo6em1(IMPC)Tcp
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
1.39×10-05
Scoc
Scocem1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.40×10-05
Agpat1
Agpat1tm1.1(KOMP)Vlcg
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.48×10-05
Chmp2b
Chmp2bem1(IMPC)Mbp
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.58×10-05
Asphd1
Asphd1em1(IMPC)Ccpcz
HOM   Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
1.58×10-05
Lcorl
Lcorlem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.65×10-05
Zfp541
Zfp541em1(IMPC)J
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.67×10-05
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
1.67×10-05
1700030J22Rik
1700030J22Rikem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.91×10-05
Scarb2
Scarb2em2(IMPC)Tcp
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
2.11×10-05
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
2.13×10-05
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
2.38×10-05
Gabre
Gabreem1(IMPC)H
HEM   Late adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.38×10-05
Ccr6
Ccr6tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.39×10-05
Poli
Politm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.40×10-05
Wbp1l
Wbp1ltm2b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
2.42×10-05
Rfc5
Rfc5em1(IMPC)J
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.59×10-05
Gabra2
Gabra2em1(IMPC)H
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.68×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.73×10-05
Arv1
Arv1em1(IMPC)J
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.76×10-05
Tmem60
Tmem60em1(IMPC)Ccpcz
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
CCP-IMG
IMPC
2.76×10-05
Arv1
Arv1em1(IMPC)J
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.81×10-05
Lep
Leptm1b(EUCOMM)Hmgu
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
2.89×10-05
Spty2d1
Spty2d1em1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.95×10-05
Arl5a
Arl5aem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.95×10-05
Tex2
Tex2em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.01×10-05
Bmp6
Bmp6em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
3.02×10-05
Cand1
Cand1em1(IMPC)Mbp
HET Late adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
3.02×10-05
Myo6
Myo6em1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
3.05×10-05
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
3.05×10-05
Arl5a
Arl5aem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.13×10-05
Ogn
Ogntm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.29×10-05
Ccdc28a
Ccdc28atm3b(EUCOMM)Wtsi
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.34×10-05
Tex21
Tex21em1(IMPC)J
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.63×10-05
Tor1a
Tor1aem1(IMPC)H
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
3.79×10-05
Ubap2l
Ubap2lem1(IMPC)Bay
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
3.94×10-05
Il33
Il33tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
3.95×10-05
Scoc
Scocem1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.97×10-05
Tex21
Tex21em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.97×10-05
Efhb
Efhbem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.99×10-05
Dhrs4
Dhrs4em1(IMPC)Hmgu
HOM Early adult decreased heart rate HR
Echo
HMGU
IMPC
4.00×10-05
Hcrt
Hcrttm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
4.00×10-05
Il18r1
Il18r1em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
4.01×10-05
Tat
Tatem1(IMPC)J
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
4.11×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
4.17×10-05
Masp1
Masp1tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
4.28×10-05
Rfc5
Rfc5em1(IMPC)J
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
4.34×10-05
Ndrg1
Ndrg1tm2b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
4.36×10-05
Unc45a
Unc45atm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
4.42×10-05
Unc45a
Unc45atm1b(EUCOMM)Hmgu
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.45×10-05
Gm5127
Gm5127em1(IMPC)J
HEM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
4.63×10-05
Ift81
Ift81tm1b(EUCOMM)Wtsi
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.79×10-05
Clock
Clockem1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
4.80×10-05
Kcna7
Kcna7em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
4.84×10-05
Meis3
Meis3tm1b(EUCOMM)Hmgu
HOM   Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
5.09×10-05
Eif3k
Eif3kem1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
5.10×10-05
Spg11
Spg11em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
5.16×10-05
Ly6g6f
Ly6g6fem1(IMPC)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
5.20×10-05
Dcps
Dcpstm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
5.55×10-05
Spock1
Spock1em1(IMPC)H
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
5.60×10-05
Ptpn18
Ptpn18em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
5.94×10-05
Ist1
Ist1em1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
6.06×10-05
Otud7a
Otud7aem1(IMPC)Bay
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
6.07×10-05
Ccr6
Ccr6tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
6.09×10-05
Masp1
Masp1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
6.11×10-05
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
6.29×10-05
Ubl7
Ubl7em1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
6.54×10-05
Snx29
Snx29tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Echo
ICS
IMPC
6.83×10-05
Chmp2b
Chmp2bem1(IMPC)Mbp
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
6.87×10-05
Lmtk2
Lmtk2em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
6.89×10-05
Ubap2l
Ubap2lem1(IMPC)Bay
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
7.20×10-05
Kcna7
Kcna7em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
7.27×10-05
Pcm1
Pcm1em1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
7.69×10-05
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
7.81×10-05
Tex2
Tex2em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
7.87×10-05
Arrdc2
Arrdc2tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
7.92×10-05
Rest
Resttm2b(EUCOMM)Wtsi
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
8.19×10-05
Ist1
Ist1em1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
8.19×10-05
Smpdl3a
Smpdl3aem1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
8.50×10-05
Tox
Toxtm1b(KOMP)Wtsi
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
8.87×10-05
Dzip1l
Dzip1lem1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
9.08×10-05
Rnd2
Rnd2em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
9.20×10-05
Ccdc28a
Ccdc28atm3b(EUCOMM)Wtsi
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
9.26×10-05
Sppl3
Sppl3em1(IMPC)Bay
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
9.30×10-05
Ldhal6b
Ldhal6bem1(IMPC)J
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
9.41×10-05
Nfat5
Nfat5tm1b(KOMP)Wtsi
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.41×10-05
Tbcc
Tbccem1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.41×10-05
Usp38
Usp38tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.60×10-05
Got1
Got1tm1b(EUCOMM)Hmgu
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.71×10-05
Tmem60
Tmem60em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
CCP-IMG
IMPC
9.84×10-05
Spock1
Spock1em1(IMPC)H
HOM   Late adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.91×10-05
Ogn
Ogntm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
9.99×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

2.18% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart rate (134/6142)

0.92% females (55/5949) 1.13% males (65/5772)

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