banner
Genes Phenotypes Help, News, Blog

Phenotype: decreased fatty acids level

Definition
reduction in the concentration of aliphatic monocarboxylic acids derived from or contained in esterified form in an animal or vegetable fat, oil or wax; natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated
Synonyms
lowered fatty acid level,  reduced fatty acid level,  decreased fatty acid level
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased fatty acids level

Total number of significant genotype-phenotype associations: 44

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Mindy1
Mindy1tm1a(EUCOMM)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acid
Clinical Chemistry		 WTSI
EuroPhenome		 6.04×10-09
Cenpo
Cenpotm1b(KOMP)Mbp 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 JAX
IMPC		 3.15×10-08
Diaph3
Diaph3tm1b(KOMP)Mbp 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 JAX
IMPC		 2.14×10-07
Rint1
Rint1tm1b(KOMP)Wtsi 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 JAX
IMPC		 3.48×10-07
Cc2d1b
Cc2d1btm1a(KOMP)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acid
Clinical Chemistry		 WTSI
EuroPhenome		 3.70×10-07
Ap4e1
Ap4e1em1(IMPC)J 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 JAX
IMPC		 6.42×10-07
Plcg2
Plcg2Ali14 		HET Early adult decreased circulating free fatty acids level Free fatty acid
Clinical Chemistry		 HMGU
EuroPhenome		 7.50×10-07
Cc2d1b
Cc2d1btm1a(KOMP)Wtsi 		HET Early adult decreased circulating free fatty acids level Free fatty acid
Clinical Chemistry		 WTSI
EuroPhenome		 9.20×10-07
Dbn1
Dbn1tm1b(KOMP)Wtsi 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 1.10×10-06
Kif26b
Kif26btm2b(KOMP)Wtsi 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 JAX
IMPC		 1.35×10-06
Cpgi15344
Cpgi15344tm1.1(NCC)WCS 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 WTSI
IMPC		 1.41×10-06
Cyb5d1
Cyb5d1tm1.1(KOMP)Vlcg 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 3.33×10-06
Rpa1
Rpa1tm1b(KOMP)Wtsi 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 3.69×10-06
Snf8
Snf8tm1a(EUCOMM)Wtsi 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 MRC Harwell
MGP		 4.56×10-06
Dop1b
Dop1btm1a(EUCOMM)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 WTSI
IMPC		 4.81×10-06
Bloc1s2
Bloc1s2tm1.1(KOMP)Mbp 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 5.23×10-06
Dpy19l3
Dpy19l3tm1a(EUCOMM)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 ICS
EuroPhenome		 5.71×10-06
Chn1
Chn1tm1.1(KOMP)Vlcg 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 6.66×10-06
Tpgs2
Tpgs2tm1.1(KOMP)Vlcg 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 7.77×10-06
Hspb3
Hspb3tm1.1(KOMP)Vlcg 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 7.88×10-06
Mtarc2
Mtarc2tm2a(EUCOMM)Hmgu 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 ICS
EuroPhenome		 9.70×10-06
Rhd
Rhdtm1e(EUCOMM)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acid
Clinical Chemistry		 WTSI
EuroPhenome		 1.31×10-05
Hmx3
Hmx3tm1Ebo 		HOM Early adult decreased circulating free fatty acids level Free fatty acid
Clinical Chemistry		 WTSI
MGP		 1.95×10-05
Resp18
Resp18tm1.1(KOMP)Vlcg 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 2.41×10-05
Gnasas1
Gnasas1tm2.1Jop 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 MRC Harwell
EuroPhenome		 2.44×10-05
Ska2
Ska2tm1b(KOMP)Wtsi 		HET   Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 2.65×10-05
Arhgef4
Arhgef4tm1a(KOMP)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 HMGU
EuroPhenome		 2.65×10-05
Entpd1
Entpd1tm1a(EUCOMM)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 MRC Harwell
EuroPhenome		 2.94×10-05
Osm
Osmtm1b(KOMP)Wtsi 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 3.20×10-05
Prep
Preptm1b(KOMP)Wtsi 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 3.65×10-05
Krt7
Krt7tm1b(KOMP)Wtsi 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 WTSI
IMPC		 3.89×10-05
Cpgi5563
Cpgi5563tm1.1(NCC)WCS 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 WTSI
IMPC		 4.70×10-05
Ceacam16
Ceacam16tm1.1(KOMP)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 5.22×10-05
Irf8
Irf8tm1b(KOMP)Wtsi 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 5.40×10-05
Pycr1
Pycr1tm1.1(KOMP)Vlcg 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 6.13×10-05
Palb2
Palb2tm1.1(KOMP)Vlcg 		HET Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 7.40×10-05
Mmp8
Mmp8tm1.1(KOMP)Vlcg 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Plasma Chemistry		 JAX
IMPC		 7.58×10-05
Rnf169
Rnf169tm1a(EUCOMM)Hmgu 		HOM   Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 MRC Harwell
EuroPhenome		 7.73×10-05
Mier1
Mier1tm1a(EUCOMM)Wtsi 		HOM Early adult decreased circulating free fatty acids level Free fatty acids
Fasted Clinical Chemistry		 WTSI
EuroPhenome		 8.25×10-05
Rfc1
Rfc1tm1b(KOMP)Mbp 		HET   Early adult decreased circulating free fatty acids level Free fatty acids
Clinical Chemistry		 JAX
IMPC		 8.44×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Clinical Blood Chemistry
Clinical Chemistry
Clinical chemistry (GMC)
Fasted Bleed
Fasted Clinical Chemistry
Plasma Chemistry
Terminal Bleed

 Phenotype associations stats

1.80% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased fatty acids level (39/2165)

0.57% females (12/2123) 0.89% males (19/2134)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter