Phenotype: abnormal sinus arrhythmia

Definition
any anomaly in the normal phenomenon of mild acceleration and slowing of the heart rate that occurs during the respiratory cycle
Synonyms
abnormal respiratory sinus arrythmia,  abnormal RSA,  abnormal SA
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal sinus arrhythmia

Total number of significant genotype-phenotype associations: 159

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Sgip1
Sgip1tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 0.00
Alkbh8
Alkbh8tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 2.67×10-28
Gja8
Gja8tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 2.42×10-24
Ppp2r2b
Ppp2r2btm1b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 2.04×10-17
Sgip1
Sgip1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 2.18×10-14
C7
C7em1(IMPC)J
HOM Late adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 8.89×10-13
Zfp706
Zfp706em1(IMPC)J
HET Early adult increased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.99×10-12
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 6.85×10-12
Ppp2r2b
Ppp2r2btm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 1.35×10-11
Slc44a4
Slc44a4tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 2.25×10-11
Casq2
Casq2tm1b(KOMP)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 2.78×10-11
C7
C7em1(IMPC)J
HOM Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.44×10-11
Fbxo10
Fbxo10em1(IMPC)J
HOM Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 1.43×10-10
Cyb5r2
Cyb5r2tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 2.57×10-10
Rph3a
Rph3atm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 2.66×10-10
Klkb1
Klkb1tm1b(EUCOMM)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 8.62×10-10
Hpse
Hpsetm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 8.63×10-10
Oscp1
Oscp1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 8.84×10-10
Prdm4
Prdm4tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 1.58×10-09
Zfp329
Zfp329em1(IMPC)J
HOM Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.72×10-09
Edc3
Edc3em1(IMPC)Tcp
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 4.79×10-09
Atp2b3
Atp2b3em1(IMPC)J
HOM Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 6.44×10-09
Xkr5
Xkr5tm1b(KOMP)Mbp
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 7.51×10-09
Zfp275
Zfp275tm1.1(NCOM)Mfgc
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 1.57×10-08
Agl
Agltm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 1.91×10-08
Grm6
Grm6tm1b(EUCOMM)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 2.01×10-08
Rps26
Rps26tm2b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 2.05×10-08
Hsf4
Hsf4tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 3.72×10-08
Rsf1
Rsf1tm1b(EUCOMM)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 5.08×10-08
Pla2g10
Pla2g10tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 5.22×10-08
Hipk2
Hipk2tm2b(EUCOMM)Hmgu
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 5.22×10-08
Casq2
Casq2tm1b(KOMP)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 5.68×10-08
Drc7
Drc7em1(IMPC)J
HOM Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 6.69×10-08
Casz1
Casz1tm1b(EUCOMM)Hmgu
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 9.87×10-08
Il17rd
Il17rdtm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 1.03×10-07
Aif1
Aif1tm1.1(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 1.11×10-07
Zdhhc24
Zdhhc24tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 1.34×10-07
Spink13
Spink13em1(IMPC)Ccpcz
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 1.71×10-07
Aif1
Aif1tm1.1(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 2.46×10-07
Mapkbp1
Mapkbp1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 2.67×10-07
Tulp3
Tulp3tm1b(EUCOMM)Hmgu
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 2.89×10-07
Spink13
Spink13em1(IMPC)Ccpcz
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV CCP-IMG | IMPC 3.07×10-07
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 3.11×10-07
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 4.55×10-07
Kcnj9
Kcnj9tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 4.61×10-07
Gja8
Gja8tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 5.03×10-07
Arrb1
Arrb1tm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 5.37×10-07
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD BCM | IMPC 5.41×10-07
Colca2
Colca2tm1b(NCOM)Mfgc
HOM Early adult increased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 5.46×10-07
Pcyox1l
Pcyox1lem1(IMPC)J
HOM Early adult increased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.68×10-07
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 6.93×10-07
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 8.32×10-07
Htr1f
Htr1ftm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 8.89×10-07
Tspo
Tspotm1b(EUCOMM)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 1.12×10-06
Myorg
Myorgtm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 1.24×10-06
Rnf223
Rnf223em1(IMPC)Ccpcz
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 1.73×10-06
Far2
Far2tm2b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 2.02×10-06
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 2.52×10-06
1700086L19Rik
1700086L19Riktm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 2.58×10-06
Xbp1
Xbp1tm1b(EUCOMM)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 2.69×10-06
Acy1
Acy1em1(IMPC)J
HOM Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 2.70×10-06
L3mbtl4
L3mbtl4em1(IMPC)Tcp
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 2.80×10-06
Auh
Auhem1(IMPC)Tcp
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 3.01×10-06
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 3.39×10-06
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 3.55×10-06
C9
C9tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 3.70×10-06
Paqr6
Paqr6tm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD BCM | IMPC 3.74×10-06
Ciao2b
Ciao2bem1(IMPC)Ccpcz
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV CCP-IMG | IMPC 3.79×10-06
Pcyox1l
Pcyox1lem1(IMPC)J
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 4.10×10-06
Aspg
Aspgem1(IMPC)Tcp
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 4.47×10-06
Serpinb5
Serpinb5tm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 4.56×10-06
Abca7
Abca7tm2b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 4.58×10-06
Vsig8
Vsig8tm1.1(KOMP)Mbp
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.54×10-06
Smo
Smotm1b(KOMP)Wtsi
HET Early adult increased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 5.72×10-06
Chtf18
Chtf18tm1b(KOMP)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 6.33×10-06
Rasal1
Rasal1em1(IMPC)J
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 6.62×10-06
Setd3
Setd3tm1.1(NCOM)Mfgc
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 6.72×10-06
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 7.32×10-06
Agpat1
Agpat1tm1.1(KOMP)Vlcg
HET Early adult increased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 7.64×10-06
Alkbh8
Alkbh8tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 8.54×10-06
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 8.82×10-06
Atrip
Atriptm1b(KOMP)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 9.28×10-06
Ltn1
Ltn1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 1.04×10-05
Mmaa
Mmaaem1(IMPC)J
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 1.06×10-05
Atp6v0a1
Atp6v0a1tm1b(EUCOMM)Hmgu
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 1.25×10-05
Mamld1
Mamld1tm1.1(NCOM)Mfgc
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 1.30×10-05
Anapc1
Anapc1em1(IMPC)J
HET Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 1.31×10-05
Masp1
Masp1tm1.1(KOMP)Vlcg
HOM Early adult increased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 1.40×10-05
Psph
Psphtm1.1(KOMP)Vlcg
HET Early adult increased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 1.48×10-05
Elof1
Elof1tm1.1(KOMP)Vlcg
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 1.54×10-05
Fbxo10
Fbxo10em1(IMPC)J
HOM Late adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 1.56×10-05
Ptgr1
Ptgr1tm1b(EUCOMM)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD BCM | IMPC 1.66×10-05
Klhl5
Klhl5tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 1.75×10-05
Tuba8
Tuba8em1(IMPC)J
HOM Late adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 1.80×10-05
Snrnp27
Snrnp27tm1b(EUCOMM)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD BCM | IMPC 1.86×10-05
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 1.93×10-05
Grtp1
Grtp1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 1.95×10-05
Bzw2
Bzw2tm1b(KOMP)Mbp
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 1.96×10-05
Slc44a4
Slc44a4tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 2.02×10-05
Ism2
Ism2tm3b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 2.20×10-05
Ccdc30
Ccdc30em1(IMPC)J
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 2.22×10-05
Cldn13
Cldn13tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 2.34×10-05
Klkb1
Klkb1tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 2.58×10-05
Tas2r116
Tas2r116em1(IMPC)Bay
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 2.67×10-05
Abca7
Abca7tm2b(EUCOMM)Hmgu
HOM Early adult increased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 2.71×10-05
Thsd1
Thsd1tm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 2.87×10-05
Serpinb5
Serpinb5tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 2.89×10-05
Vps37d
Vps37dtm2b(EUCOMM)Wtsi
HET Early adult increased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 2.89×10-05
Fbxl16
Fbxl16tm1b(KOMP)Wtsi
HET Early adult increased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 2.91×10-05
Meis1
Meis1tm1b(EUCOMM)Hmgu
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 2.93×10-05
Ube2m
Ube2mtm1.1(KOMP)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 2.97×10-05
Ltbp2
Ltbp2tm2b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.05×10-05
Boc
Boctm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 3.06×10-05
Pcnx2
Pcnx2em1(IMPC)J
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.07×10-05
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 3.13×10-05
Cldn13
Cldn13tm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.22×10-05
Arfip2
Arfip2tm1b(EUCOMM)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 3.42×10-05
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 3.58×10-05
Rtl10
Rtl10em1(IMPC)J
HOM Late adult increased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 3.63×10-05
Edc3
Edc3em1(IMPC)Tcp
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 3.68×10-05
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.74×10-05
Nagk
Nagktm1b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 3.81×10-05
Theg
Thegtm1b(KOMP)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.84×10-05
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 3.95×10-05
Nagk
Nagktm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 4.07×10-05
Rps26
Rps26tm2b(EUCOMM)Hmgu
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD HMGU | IMPC 4.13×10-05
Ciao2b
Ciao2bem1(IMPC)Ccpcz
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 4.22×10-05
Hpse
Hpsetm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 4.27×10-05
Mrps22
Mrps22tm1.1(KOMP)Vlcg
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 4.31×10-05
Lrp1
Lrp1tm1.1(KOMP)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 4.38×10-05
Agl
Agltm1b(EUCOMM)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD MRC Harwell | IMPC 4.56×10-05
Krt28
Krt28em1(IMPC)Ccpcz
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 4.60×10-05
Tuba8
Tuba8em1(IMPC)J
HOM Late adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 4.66×10-05
Prdm14
Prdm14em1(IMPC)Bay
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 4.66×10-05
Ddx39a
Ddx39atm1b(KOMP)Wtsi
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD BCM | IMPC 5.23×10-05
Drc7
Drc7em1(IMPC)J
HOM Late adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.24×10-05
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 5.26×10-05
Mmp8
Mmp8tm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 5.35×10-05
C9
C9tm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 5.41×10-05
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 5.76×10-05
Far2
Far2tm2b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD JAX | IMPC 5.79×10-05
Dusp16
Dusp16em1(IMPC)Tcp
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 5.93×10-05
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 6.23×10-05
Fcmr
Fcmrtm1b(KOMP)Wtsi
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 6.46×10-05
Chst14
Chst14em1(IMPC)Tcp
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 7.04×10-05
Gsta4
Gsta4tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 7.13×10-05
Zfp275
Zfp275tm1.1(NCOM)Mfgc
HEM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 7.49×10-05
Mamld1
Mamld1tm1.1(NCOM)Mfgc
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 7.63×10-05
Dcaf8
Dcaf8em1(IMPC)Ccpcz
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 7.70×10-05
Eif4enif1
Eif4enif1em1(IMPC)Tcp
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 7.91×10-05
Foxj3
Foxj3tm1a(EUCOMM)Wtsi
HET Early adult increased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 8.80×10-05
Zfp275
Zfp275tm1.1(NCOM)Mfgc
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 9.42×10-05
Rnf14
Rnf14em1(IMPC)Ccpcz
HOM Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD CCP-IMG | IMPC 9.63×10-05
Exoc8
Exoc8tm1.1(KOMP)Vlcg
HET Early adult abnormal sinus arrhythmia Electrocardiogram (ECG) | rMSSD TCP | IMPC 9.74×10-05

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 The way we measure

 Phenotype associations stats

4.79% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal sinus arrhythmia (120/2503)

2.56% females (63/2459) 0.73% males (18/2454)

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