Phenotype: increased cardiac output

Definition
greater than normal blood volume pumped by each ventricle per minute
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased cardiac output

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Psd3
Psd3em1(IMPC)H
HOM Late adult increased cardiac output Cardiac Output
Echo
MRC Harwell
IMPC
6.51×10-10
Ces1a
Ces1atm1b(KOMP)Wtsi
HOM Early adult increased cardiac output Cardiac Output
Echo
BCM
IMPC
1.24×10-06
Hycc1
Hycc1em1(IMPC)Ccpcz
HOM Early adult increased cardiac output Cardiac Output
Echo
CCP-IMG
IMPC
3.89×10-06
Man2a1
Man2a1em1(IMPC)Hmgu
HOM Early adult increased cardiac output Cardiac Output
Echo
HMGU
IMPC
3.44×10-05
Zfp300
Zfp300em1(IMPC)Bay
HOM Early adult increased cardiac output Cardiac Output
Echo
BCM
IMPC
4.60×10-05
Vars2
Vars2em1(IMPC)Bay
HET Early adult increased cardiac output Cardiac Output
Echo
BCM
IMPC
6.55×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.33% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased cardiac output (6/1835)

0.11% females (2/1817) 0.26% males (4/1535)

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