Phenotype: increased cardiac output

Definition
greater than normal blood volume pumped by each ventricle per minute
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased cardiac output

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Ces1a
Ces1atm1b(KOMP)Wtsi
HOM Early adult increased cardiac output Cardiac Output
Echo
BCM
IMPC
1.24×10-06
Fam126a
Fam126aem1(IMPC)Ccpcz
HOM Early adult increased cardiac output Cardiac Output
Echo
CCP-IMG
IMPC
4.02×10-06
Man2a1
Man2a1em1(IMPC)Hmgu
HOM Early adult increased cardiac output Cardiac Output
Echo
HMGU
IMPC
3.44×10-05
Zfp300
Zfp300em1(IMPC)Bay
HOM   Early adult increased cardiac output Cardiac Output
Echo
BCM
IMPC
4.60×10-05
Vars2
Vars2em1(IMPC)Bay
HET Early adult increased cardiac output Cardiac Output
Echo
BCM
IMPC
6.55×10-05
Grem2
Grem2em1(IMPC)Bay
HET   Early adult increased cardiac output Cardiac Output
Echo
BCM
IMPC
9.46×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.35% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased cardiac output (6/1701)

0.06% females (1/1680) 0.21% males (3/1405)



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