Phenotype: increased heart weight

Definition
greater than average weight of the heart compared to controls
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased heart weight

Total number of significant genotype-phenotype associations: 291

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
0.00
Mybpc3
Mybpc3tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
1.60×10-25
4921509C19Rik
4921509C19Riktm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.52×10-25
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.38×10-20
Atp13a3
Atp13a3em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.46×10-20
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.56×10-16
Ndufs3
Ndufs3tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
6.88×10-15
Resp18
Resp18tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.00×10-14
Fsd2
Fsd2em1(IMPC)Mbp
HOM Late adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.48×10-14
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
2.37×10-14
Grm6
Grm6tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.87×10-13
Ptgis
Ptgisem1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
7.63×10-13
Xpo1
Xpo1em1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.55×10-12
Actn4
Actn4tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
5.00×10-12
AU021092
AU021092tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.93×10-11
Pram1
Pram1tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
3.18×10-11
Far2
Far2tm2b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.52×10-11
Mmp8
Mmp8tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.84×10-11
Plce1
Plce1em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
8.24×10-11
Agl
Agltm1b(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.85×10-10
Frmd6
Frmd6em1(IMPC)H
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.14×10-10
Trappc2l
Trappc2lem1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.86×10-10
Gnas
Gnastm1Jop
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
3.55×10-10
Dcbld2
Dcbld2tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
3.65×10-10
Slc6a3
Slc6a3tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.52×10-10
Zfp787
Zfp787em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.53×10-10
Fam120a
Fam120aem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.02×10-10
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
9.53×10-10
Rab19
Rab19tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
1.00×10-09
Tmem203
Tmem203em1(IMPC)H
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.24×10-09
Ppp4c
Ppp4cem1(IMPC)Ics
HET Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
1.26×10-09
Dusp18
Dusp18em1(IMPC)J
HOM Late adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.31×10-09
Cygb
Cygbtm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.74×10-09
Kdm4b
Kdm4btm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
2.82×10-09
Mon2
Mon2em1(IMPC)J
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.46×10-09
Atr
Atrtm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.83×10-09
Smoc1
Smoc1tm1b(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
4.83×10-09
Rbm22
Rbm22em1(IMPC)Mbp
HET Late adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
6.13×10-09
Srcin1
Srcin1tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.23×10-09
Cmtr2
Cmtr2tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.00×10-09
Msn
Msntm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.85×10-09
Ap1ar
Ap1artm2b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
BCM
IMPC
1.19×10-08
Cast
Casttm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.27×10-08
Lcn2
Lcn2tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.51×10-08
Tpm1
Tpm1tm1a(EUCOMM)Wtsi
HET   Early adult increased heart weight Heart weight
Heart weight/tibia length
WTSI
EuroPhenome
1.73×10-08
Dynlrb2
Dynlrb2tm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
2.18×10-08
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
2.75×10-08
Dipk1a
Dipk1atm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
2.84×10-08
Elk1
Elk1tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.87×10-08
Gpld1
Gpld1tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.96×10-08
Ppp2r5c
Ppp2r5cem1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.01×10-08
Fgd5
Fgd5em1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.82×10-08
Slitrk2
Slitrk2em1(IMPC)Mbp
HEM   Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
6.23×10-08
Rhpn1
Rhpn1tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
6.57×10-08
Krt74
Krt74tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
8.34×10-08
Nfatc4
Nfatc4tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.46×10-08
Lrig1
Lrig1tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
9.78×10-08
Pskh1
Pskh1tm1b(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.15×10-07
Atg2b
Atg2bem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.56×10-07
Shisa6
Shisa6em1(IMPC)Tcp
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.70×10-07
Rab24
Rab24tm1.1(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.22×10-07
2810408A11Rik
2810408A11Riktm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
2.32×10-07
Col1a2
Col1a2tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
BCM
IMPC
2.38×10-07
Letmd1
Letmd1em1(IMPC)KMPC
HOM   Late adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
2.47×10-07
Hirip3
Hirip3tm1b(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.54×10-07
Pdp1
Pdp1em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.55×10-07
Mapkbp1
Mapkbp1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.72×10-07
Cd9
Cd9tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
ICS
EuroPhenome
2.75×10-07
Rasa1
Rasa1tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.04×10-07
Zfp42
Zfp42tm1b(KOMP)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.38×10-07
Hspa5
Hspa5tm1.1(KOMP)Vlcg
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.81×10-07
Rasa3
Rasa3tm1b(KOMP)J
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.33×10-07
Sik1
Sik1tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.66×10-07
Pabpc4
Pabpc4tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
4.67×10-07
Ube2f
Ube2fem1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
4.75×10-07
Cyb5d2
Cyb5d2tm1.1(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.86×10-07
Zfp52
Zfp52em1(IMPV)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.18×10-07
Hsd17b11
Hsd17b11tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.31×10-07
Trim66
Trim66tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
5.79×10-07
Krt17
Krt17tm1.1(KOMP)Vlcg
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.88×10-07
Acvr1c
Acvr1ctm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.90×10-07
Galnt12
Galnt12em1(IMPC)J
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.10×10-07
Etfb
Etfbem1(IMPC)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
HMGU
IMPC
6.82×10-07
Tmem181a
Tmem181atm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.21×10-07
Car7
Car7tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.44×10-07
Stox2
Stox2tm2b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.70×10-07
Zkscan17
Zkscan17tm1b(EUCOMM)Wtsi
HET   Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
8.11×10-07
Spz1
Spz1em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
8.42×10-07
Mos
Mostm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.68×10-07
Pibf1
Pibf1tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.78×10-07
Nos3
Nos3em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
8.99×10-07
Vcpkmt
Vcpkmttm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.26×10-07
Dcp2
Dcp2tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
1.07×10-06
Mpdz
Mpdzem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.16×10-06
Rbm22
Rbm22em1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.32×10-06
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.43×10-06
Cdk12
Cdk12em1(IMPC)Tcp
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.51×10-06
Ssbp2
Ssbp2tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.55×10-06
Gabarapl2
Gabarapl2tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.58×10-06
Hivep1
Hivep1tm1(KOMP)Mbp
HET   Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.60×10-06
Epb41l4a
Epb41l4atm1b(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.67×10-06
Polr2h
Polr2htm1.1(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.70×10-06
Il24
Il24tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.75×10-06
Tmem79
Tmem79tm1.1(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.76×10-06
Ube2a
Ube2atm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.79×10-06
Tbl1xr1
Tbl1xr1tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
HMGU
IMPC
1.81×10-06
Vps33a
Vps33aem2(IMPC)Tcp
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
2.02×10-06
Dbnl
Dbnltm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
2.07×10-06
Cenpo
Cenpotm1b(KOMP)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.18×10-06
Capn5
Capn5tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
2.40×10-06
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Late adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
2.43×10-06
Ptpn5
Ptpn5tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.75×10-06
Epb41l5
Epb41l5tm1a(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
2.76×10-06
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.81×10-06
Afg1l
Afg1lem1(IMPC)KMPC
HOM Late adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
2.98×10-06
Pcsk5
Pcsk5tm1b(KOMP)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.14×10-06
Sec1
Sec1tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
3.42×10-06
Rab5a
Rab5atm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.52×10-06
Bhlhe40
Bhlhe40tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.78×10-06
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.78×10-06
Fgf9
Fgf9tm1b(KOMP)Wtsi
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.00×10-06
Pde2a
Pde2aem1(IMPC)H
HET Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
4.24×10-06
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
4.80×10-06
Lama4
Lama4tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.86×10-06
Rimklb
Rimklbtm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.96×10-06
Fbxo43
Fbxo43em1(IMPC)Marc
HOM Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
5.05×10-06
Gle1
Gle1tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
5.10×10-06
Hspb2
Hspb2tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.49×10-06
Cd36
Cd36em1(IMPC)Mbp
HOM Late adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
5.63×10-06
Arcn1
Arcn1tm1a(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart weight/tibia length
ICS
EuroPhenome
5.91×10-06
Cops7a
Cops7atm1b(KOMP)Mbp
HOM   Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
6.05×10-06
Catsperz
Catsperztm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.20×10-06
Btg1
Btg1em1(IMPC)Mbp
HOM   Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
6.27×10-06
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
6.76×10-06
Osm
Osmtm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.89×10-06
Hcn1
Hcn1em1(IMPC)H
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
6.95×10-06
Rab43
Rab43tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.00×10-06
Arrb1
Arrb1tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.10×10-06
Mid1
Mid1em1(IMPC)Mbp
HET   Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
7.14×10-06
Nemf
Nemftm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.29×10-06
Gsto2
Gsto2tm2a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
7.30×10-06
Spns1
Spns1tm1e(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart weight/tibia length
ICS
EuroPhenome
7.62×10-06
Exd1
Exd1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
7.81×10-06
Xylb
Xylbtm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
8.35×10-06
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.76×10-06
Neurl2
Neurl2tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.30×10-06
Rap1gap2
Rap1gap2tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
9.35×10-06
Hs3st3a1
Hs3st3a1tm1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
9.88×10-06
Glrb
Glrbem1(IMPC)Tcp
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
9.92×10-06
Rilpl2
Rilpl2tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.00×10-05
Rnf31
Rnf31tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.01×10-05
Rrad
Rradtm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.01×10-05
Robo3
Robo3em1(IMPC)H
HET Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.08×10-05
Htr1b
Htr1btm1.1(KOMP)Vlcg
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.10×10-05
Msx1
Msx1tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.11×10-05
Lrp1
Lrp1tm1.1(KOMP)Wtsi
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.18×10-05
Stx11
Stx11em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.18×10-05
Mplkip
Mplkiptm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.24×10-05
Chtf18
Chtf18tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.26×10-05
Kif26b
Kif26btm2b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.27×10-05
Ctsa
Ctsatm2b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.31×10-05
Rcc2
Rcc2tm1b(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.41×10-05
Phf20l1
Phf20l1em1(IMPC)Tcp
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.41×10-05
Ier5l
Ier5lem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.46×10-05
Cdc20
Cdc20tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.46×10-05
Acsl5
Acsl5tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.51×10-05
Ddhd1
Ddhd1tm1a(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
1.54×10-05
Psmd14
Psmd14tm1b(NCOM)Cmhd
HET Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
1.54×10-05
Sptssb
Sptssbtm1b(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.66×10-05
Jam2
Jam2tm1.1(KOMP)Mbp
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.77×10-05
Odc1
Odc1tm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.94×10-05
Mgrn1
Mgrn1em1(IMPC)Tcp
HET   Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
2.04×10-05
Izumo1r
Izumo1rtm2a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
2.12×10-05
Tdo2
Tdo2tm1b(KOMP)Mbp
HET Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.30×10-05
Hsd17b1
Hsd17b1tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.31×10-05
4933427D14Rik
4933427D14Riktm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.32×10-05
Mpv17
Mpv17em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.32×10-05
Man2a1
Man2a1em1(IMPC)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart Weight
HMGU
IMPC
2.34×10-05
Cdk15
Cdk15tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.46×10-05
Bod1
Bod1tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
2.50×10-05
Zer1
Zer1em1(IMPC)J
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.51×10-05
4932438A13Rik
4932438A13Riktm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.54×10-05
Rpa1
Rpa1tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.66×10-05
Itga8
Itga8tm1b(KOMP)Wtsi
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.67×10-05
Ncoa5
Ncoa5tm1.1(KOMP)Mbp
HET Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.68×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
2.68×10-05
H2-M5
H2-M5tm1(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
2.74×10-05
Atg4c
Atg4cem2(IMPC)Marc
HOM Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
2.74×10-05
Akr1d1
Akr1d1tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.76×10-05
Cln8
Cln8em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.85×10-05
Taco1
Taco1em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.92×10-05
Arsj
Arsjem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.95×10-05
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
2.97×10-05
Setd2
Setd2tm1b(NCOM)Mfgc
HOM   Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
3.07×10-05
Crabp2
Crabp2em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.10×10-05
Rgl1
Rgl1em1(IMPC)Mbp
HET   Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.21×10-05
Lrrc15
Lrrc15tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.23×10-05
Cp
Cptm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.37×10-05
Stk38
Stk38tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.41×10-05
Cacna1i
Cacna1itm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
BCM
IMPC
3.41×10-05
A1cf
A1cftm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.41×10-05
Slc16a2
Slc16a2tm1a(KOMP)Wtsi
HEM   Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
3.48×10-05
Gimap8
Gimap8tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.73×10-05
Rab36
Rab36tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.84×10-05
Tmprss6
Tmprss6tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
3.95×10-05
Nek2
Nek2tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.96×10-05
Fhod1
Fhod1em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.00×10-05
Kcng2
Kcng2em1(IMPC)Bay
HOM Early adult increased heart weight Heart weight
Heart Weight
BCM
IMPC
4.06×10-05
Slc45a3
Slc45a3tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.17×10-05
Slc25a35
Slc25a35tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.22×10-05
Lpar6
Lpar6tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.22×10-05
Dusp16
Dusp16em1(IMPC)Tcp
HOM   Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
4.36×10-05
Mrps25
Mrps25tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.40×10-05
Dcdc2c
Dcdc2ctm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
4.43×10-05
Hipk2
Hipk2tm2b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
4.50×10-05
Lilr4b
Lilr4bem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.59×10-05
Tbc1d20
Tbc1d20em1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.61×10-05
Cdk19
Cdk19em1(IMPC)J
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.71×10-05
Klhl3
Klhl3tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
4.78×10-05
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Early adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
4.79×10-05
Cep68
Cep68em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.96×10-05
Wrap53
Wrap53tm1b(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
4.98×10-05
Cmtr1
Cmtr1em1(IMPC)J
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.02×10-05
Ttc39a
Ttc39atm1b(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
5.16×10-05
Parp8
Parp8tm1.1(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.23×10-05
Pcsk4
Pcsk4tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.45×10-05
Ergic2
Ergic2em1(IMPC)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
HMGU
IMPC
5.49×10-05
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
BCM
IMPC
5.69×10-05
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
5.81×10-05
Armc2
Armc2tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
5.89×10-05
Bzw2
Bzw2tm1b(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.89×10-05
Rab34
Rab34tm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.89×10-05
Cln6
Cln6tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
5.97×10-05
C9
C9tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.01×10-05
Emilin3
Emilin3tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.04×10-05
Sprr3
Sprr3tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.08×10-05
Pan2
Pan2tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
6.13×10-05
Zfp961
Zfp961tm1.1(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.21×10-05
Hsf4
Hsf4tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.47×10-05
Plaat3
Plaat3em1(IMPC)Tcp
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
6.49×10-05
Myo3b
Myo3btm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.52×10-05
Asb10
Asb10tm2b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.65×10-05
Vsig8
Vsig8tm1.1(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.68×10-05
Mrgprx1
Mrgprx1em1(IMPC)Tcp
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
6.70×10-05
Setd6
Setd6tm1.1(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.74×10-05
Ide
Idetm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
6.75×10-05
Pacsin2
Pacsin2tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.75×10-05
Foxo3
Foxo3tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.95×10-05
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
6.99×10-05
Pate4
Pate4tm1.1(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.24×10-05
Ywhaz
Ywhaztm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
7.39×10-05
Hdgfl1
Hdgfl1em1(IMPC)Tcp
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
7.42×10-05
Dap
Daptm1a(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
7.50×10-05
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
RBRC
IMPC
7.62×10-05
Kctd9
Kctd9em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.65×10-05
Hddc2
Hddc2em1(IMPC)H
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
7.69×10-05
Hspb1
Hspb1tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.70×10-05
Sirt2
Sirt2tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
7.83×10-05
Wdr47
Wdr47tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
8.34×10-05
Tnks
Tnksem1(IMPC)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart Weight
HMGU
IMPC
8.37×10-05
Zbtb32
Zbtb32tm1b(KOMP)Mbp
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.39×10-05
Myo6
Myo6em1(IMPC)Tcp
HOM   Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
8.49×10-05
Tmem255b
Tmem255btm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
8.68×10-05
Stk16
Stk16tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.72×10-05
Dnajb3
Dnajb3tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.79×10-05
Zfp398
Zfp398em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
8.84×10-05
Pxdc1
Pxdc1tm1e.1(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
8.98×10-05
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
8.98×10-05
Elof1
Elof1tm1.1(KOMP)Vlcg
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.00×10-05
Pth2r
Pth2rtm2a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
9.62×10-05
Gpr142
Gpr142tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.71×10-05
Zfp14
Zfp14tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.95×10-05
Ap4e1
Ap4e1tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
9.96×10-05
Vsig4
Vsig4tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.99×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

3.71% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart weight (271/7299)

0.71% females (50/7065) 2.46% males (174/7059)

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