Phenotype: dilated heart left ventricle

Definition
the luminal space of the lower left chamber of the heart is increased in volume or area, usually with an increase in contained fluid
Synonyms
left ventricular dilation,  dilated left ventricle,  left ventricle dilation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with dilated heart left ventricle

Total number of significant genotype-phenotype associations: 18

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM Early adult dilated heart left ventricle Echo | End-Systolic Diameter MRC Harwell | IMPC 0.00
Ints6l
Ints6lem1(IMPC)Marc
HEM Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 3.09×10-09
Mapkap1
Mapkap1tm1b(EUCOMM)Wtsi
HET Early adult dilated heart left ventricle Echo | LVIDd BCM | IMPC 3.43×10-07
Dsg2
Dsg2tm1b(EUCOMM)Wtsi
HOM Early adult dilated heart left ventricle Echo | LVIDs BCM | IMPC 4.22×10-07
Col1a2
Col1a2tm1b(EUCOMM)Wtsi
HOM Early adult dilated heart left ventricle Echo | LVIDd BCM | IMPC 1.05×10-06
Arhgap40
Arhgap40tm1b(KOMP)Wtsi
HOM Early adult dilated heart left ventricle Echo | End-Diastolic Diameter BCM | IMPC 2.33×10-06
Grem2
Grem2em1(IMPC)Bay
HET Early adult dilated heart left ventricle Echo | End-Diastolic Diameter BCM | IMPC 4.45×10-06
Gsdmd
Gsdmdem1(IMPC)Marc
HOM Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 5.32×10-06
Ap1ar
Ap1artm2b(EUCOMM)Hmgu
HOM Early adult dilated heart left ventricle Echo | LVIDd BCM | IMPC 7.83×10-06
Tmem169
Tmem169em1(IMPC)Mhzh
HOM Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 8.63×10-06
Snx25
Snx25tm1b(KOMP)Wtsi
HET Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 1.98×10-05
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HOM Early adult dilated heart left ventricle Echo | End-Systolic Diameter BCM | IMPC 2.60×10-05
Fbxo10
Fbxo10tm1b(KOMP)Wtsi
HOM Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 2.93×10-05
Abhd3
Abhd3em1(IMPC)Marc
HOM Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 3.58×10-05
Fmc1
Fmc1tm1b(EUCOMM)Wtsi
HET Early adult dilated heart left ventricle Echo | End-Systolic Diameter BCM | IMPC 7.90×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.91% of tested genes with null mutations on a B6N genetic background have a phenotype association to dilated heart left ventricle (15/1653)

0.12% females (2/1632) 0.51% males (7/1360)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter