Phenotype: small heart

Definition
reduced size of the heart relative to average
Synonyms
decreased heart size,  reduced heart size
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with small heart

Total number of significant genotype-phenotype associations: 160

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ache
Acheem1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Adamts1
Adamts1em1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Bbs1
Bbs1em1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Cacna1i
Cacna1itm1b(KOMP)Wtsi
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart BCM | IMPC 0.00
Cand1
Cand1em1(IMPC)Mbp
HET Late adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Csnk2a2
Csnk2a2em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Dagla
Daglatm1a(EUCOMM)Wtsi
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Dennd1a
Dennd1aem1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Dlx3
Dlx3em1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Duox2
Duox2em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Fam83h
Fam83hem1(IMPC)Ccpcz
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart CCP-IMG | IMPC 0.00
Gh
Ghtm1.1(KOMP)Vlcg
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Ghrh
Ghrhtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 0.00
H1f0
H1f0em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Hectd3
Hectd3tm1(NCOM)Cmhd
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Irf3
Irf3em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Kdm1a
Kdm1atm1(NCOM)Mfgc
HET Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Lhcgr
Lhcgrtm1(KOMP)Vlcg
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Npas2
Npas2em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Pdcd6ip
Pdcd6ipem1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Pramel12
Pramel12em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Slc6a2
Slc6a2tm1b(EUCOMM)Hmgu
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MRC Harwell | IMPC 0.00
Trh
Trhem1(IMPC)Tcp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart TCP | IMPC 0.00
Wdr11
Wdr11em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Wdr11
Wdr11em1(IMPC)Mbp
HET Late adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Gh
Ghtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.59×10-42
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.23×10-24
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 1.01×10-22
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.38×10-18
Map7d1
Map7d1em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.05×10-12
Duox2
Duox2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.51×10-12
Kctd1
Kctd1em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.78×10-11
Tmem248
Tmem248tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.66×10-10
Tlr4
Tlr4tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.08×10-10
Lep
Leptm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 5.64×10-10
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.23×10-10
Camk1d
Camk1dem1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 7.28×10-10
Ptp4a3
Ptp4a3em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.94×10-09
Yipf6
Yipf6em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.03×10-09
Kiss1r
Kiss1rtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 6.59×10-09
Tox3
Tox3tm1b(KOMP)Mbp
HET Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 7.62×10-09
Rab28
Rab28em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.10×10-09
Mul1
Mul1em1(IMPC)H
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 9.78×10-09
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 2.82×10-08
Eid2
Eid2em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.33×10-08
Mylk4
Mylk4em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.94×10-08
Gopc
Gopctm1e.1(EUCOMM)Wtsi
HET Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.02×10-08
Hrh4
Hrh4tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 4.97×10-08
Ly6g6d
Ly6g6dtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight HMGU | IMPC 1.04×10-07
Naa10
Naa10em1(IMPC)Mbp
HEM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.85×10-07
Slc25a25
Slc25a25tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.12×10-07
Zfp202
Zfp202em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.53×10-07
Nr1h3
Nr1h3tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 2.93×10-07
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 3.28×10-07
Asic1
Asic1em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 3.68×10-07
2510009E07Rik
2510009E07Rikem1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart Weight | Heart weight CCP-IMG | IMPC 3.90×10-07
Elmod3
Elmod3em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.88×10-07
Lrrtm1
Lrrtm1em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.42×10-07
Trh
Trhem1(IMPC)Tcp
HOM Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 6.87×10-07
G2e3
G2e3em1(IMPC)Tcp
HOM Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 7.34×10-07
Siglec1
Siglec1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.76×10-06
Opn3
Opn3em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.80×10-06
P2rx4
P2rx4tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.40×10-06
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 2.84×10-06
Rnf24
Rnf24em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.86×10-06
Srek1
Srek1em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.91×10-06
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 3.42×10-06
Mtmr12
Mtmr12tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 3.94×10-06
Ythdc2
Ythdc2em1(IMPC)Bay
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 4.33×10-06
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.56×10-06
Shfl
Shfltm1.1(KOMP)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.01×10-06
Nans
Nansem1(IMPC)Tcp
HET Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 5.11×10-06
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 5.34×10-06
Kash5
Kash5em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 6.12×10-06
Clrn2
Clrn2em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 6.72×10-06
Dnm1l
Dnm1ltm1b(KOMP)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 8.21×10-06
Nucb1
Nucb1em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.47×10-06
Slc25a21
Slc25a21tm1d(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 9.11×10-06
Grin2d
Grin2dtm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 9.24×10-06
Prf1
Prf1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 9.45×10-06
Herc1
Herc1em3(IMPC)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 9.77×10-06
Nucb1
Nucb1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.04×10-05
Cbarp
Cbarptm2e.1(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 1.15×10-05
Ube2u
Ube2utm1e.1(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.24×10-05
Arhgap11a
Arhgap11aem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.33×10-05
Tex45
Tex45tm3b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 1.57×10-05
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.60×10-05
Il17rd
Il17rdtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.69×10-05
Dnd1
Dnd1em1(IMPC)Bay
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 1.69×10-05
Thsd4
Thsd4em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.73×10-05
Ap1g1
Ap1g1tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.76×10-05
Otop3
Otop3tm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 1.80×10-05
Kctd15
Kctd15tm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 1.85×10-05
Kcnt2
Kcnt2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.05×10-05
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.34×10-05
Ifitm1
Ifitm1not yet assigned
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 2.37×10-05
Slc22a8
Slc22a8tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.46×10-05
Atrn
Atrntm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.95×10-05
Coq2
Coq2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.95×10-05
Adgrf3
Adgrf3em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.10×10-05
Tle4
Tle4em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.20×10-05
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 3.28×10-05
Dram1
Dram1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.29×10-05
Krt26
Krt26em1(IMPC)KMPC
HOM Late adult decreased heart weight Heart Weight | Heart weight KMPC | IMPC 3.37×10-05
Vwa1
Vwa1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.94×10-05
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
HOM Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 3.97×10-05
Kctd13
Kctd13em2(IMPC)Ics
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 4.01×10-05
Egr4
Egr4tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 4.02×10-05
Neurl4
Neurl4em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 4.11×10-05
Fundc1
Fundc1tm1c(KOMP)Wtsi
HEM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 4.25×10-05
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight RBRC | IMPC 4.30×10-05
Il31ra
Il31ratm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.39×10-05
Myc
Mycem1(IMPC)KMPC
HET Early adult decreased heart weight Heart Weight | Heart weight KMPC | IMPC 4.58×10-05
Otogl
Otoglem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.61×10-05
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 4.61×10-05
Cntnap5a
Cntnap5aem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 5.04×10-05
Fndc9
Fndc9tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.89×10-05
Pcyox1l
Pcyox1lem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 5.89×10-05
Gldc
Gldctm1a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 6.19×10-05
Usp24
Usp24tm1a(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 6.24×10-05
F10
F10tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 6.48×10-05
Tpgs2
Tpgs2tm1.1(KOMP)Vlcg
HOM Late adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 6.82×10-05
Eng
Engem1(IMPC)Mbp
HET Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 6.89×10-05
Arhgap33
Arhgap33tm1b(KOMP)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 6.91×10-05
Ncor2
Ncor2Ncor2
HET Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 6.99×10-05
Asic2
Asic2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 7.71×10-05
Gpr61
Gpr61em1(IMPC)Bay
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 7.83×10-05
Wdr81
Wdr81em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 8.45×10-05
Pawr
Pawrtm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 8.51×10-05
Vsir
Vsirtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.52×10-05
Heca
Hecaem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 8.95×10-05
Phf11a
Phf11atm1b(NCOM)Mfgc
HET Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 9.06×10-05
Asb16
Asb16em1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart Weight | Heart weight CCP-IMG | IMPC 9.22×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

104.07% of tested genes with null mutations on a B6N genetic background have a phenotype association to small heart (128/123)

38.14% females (45/118) 82.73% males (91/110)

Select a parameter    



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