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Phenotype: abnormal circulating insulin level

Definition
any anomaly in the blood concentration of the polypeptide hormone, secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids
Synonyms
abnormal blood insulin level
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal circulating insulin level

Total number of significant genotype-phenotype associations: 69

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Cxcr1
Cxcr1tm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 0.00
F730043M19Rik
F730043M19Riktm1b(NCC)WCS 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 0.00
Herc1
Herc1em3(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 0.00
Mrap2
Mrap2tm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 0.00
Nudcd3
Nudcd3em1(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 0.00
Pold3
Pold3tm1b(EUCOMM)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 0.00
Trappc10
Trappc10tm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 2.21×10-43
Adcy9
Adcy9tm1b(EUCOMM)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.07×10-33
Fbf1
Fbf1tm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 4.09×10-29
Psg27
Psg27em1(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.43×10-28
Paupar
Paupartm1.1(NCC)WCS 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.53×10-28
Tcf20
Tcf20em1(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 5.00×10-24
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 6.27×10-17
Trappc9
Trappc9tm1a(EUCOMM)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 9.94×10-16
Pvr
Pvrem1(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 7.75×10-15
Tmem163
Tmem163em1(IMPC)Mbp 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 3.18×10-14
Txndc5
Txndc5tm1.1(KOMP)Vlcg 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 2.90×10-13
Cacna1f
Cacna1ftm1.1(KOMP)Vlcg 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 1.99×10-12
Plet1
Plet1em1(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.76×10-11
Elk1
Elk1tm1.1(KOMP)Vlcg 		HEM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 4.63×10-11
Txndc5
Txndc5tm1.1(KOMP)Vlcg 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 8.79×10-11
Casp4
Casp4tm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 9.31×10-10
Rabl2
Rabl2tm1.1(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 2.35×10-09
Larp4b
Larp4bem1(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 3.83×10-09
Jmjd7
Jmjd7em1(IMPC)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 4.81×10-09
Ppy
Ppytm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 HMGU
IMPC		 6.32×10-09
Usp1
Usp1tm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 9.77×10-09
Sfxn3
Sfxn3tm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.61×10-08
Rbmx
Rbmxtm2a(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.93×10-08
Dcx
Dcxtm1a(EUCOMM)Wtsi 		HEM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 3.86×10-08
Pepd
Pepdtm1a(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 8.80×10-08
Wdr37
Wdr37tm1a(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 8.95×10-08
Spryd3
Spryd3tm1b(EUCOMM)Hmgu 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 HMGU
IMPC		 8.95×10-08
Gnl3
Gnl3tm1b(EUCOMM)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.12×10-07
Bnip3
Bnip3em1(IMPC)Mbp 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 1.98×10-07
Farsa
Farsatm2a(EUCOMM)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 5.06×10-07
Sec61b
Sec61bem1(IMPC)Mbp 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 5.89×10-07
Kmt2e
Kmt2etm1.2(IMPC)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 6.03×10-07
Dusp3
Dusp3tm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 7.11×10-07
Lipe
Lipetm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 7.73×10-07
Arid3a
Arid3atm1b(KOMP)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 1.08×10-06
Glt8d2
Glt8d2tm1a(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.98×10-06
Cpgi23001
Cpgi23001tm1.1(NCC)WCS 		HEM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 2.49×10-06
Ndufb9
Ndufb9tm1b(EUCOMM)Hmgu 		HET   Early adult increased circulating insulin level Insulin
Insulin Blood Level		 HMGU
IMPC		 2.58×10-06
Acad12
Acad12tm1b(EUCOMM)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 3.64×10-06
Selenbp1
Selenbp1tm1b(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 4.19×10-06
Alg2
Alg2tm1.1(KOMP)Vlcg 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 4.66×10-06
Palb2
Palb2tm1.1(KOMP)Vlcg 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 8.22×10-06
Adgrb1
Adgrb1tm2a(EUCOMM)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 8.98×10-06
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi 		HOM   Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 9.14×10-06
Ncald
Ncaldtm1.1(KOMP)Vlcg 		HOM   Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 1.67×10-05
Ankhd1
Ankhd1tm1a(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 1.80×10-05
Adamts15
Adamts15tm1.1(KOMP)Vlcg 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 1.99×10-05
Cog3
Cog3tm1b(EUCOMM)Hmgu 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 HMGU
IMPC		 2.05×10-05
Ncoa2
Ncoa2em1(IMPC)Mbp 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 2.73×10-05
Zbtb32
Zbtb32tm1b(KOMP)Mbp 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 2.80×10-05
Pias2
Pias2tm1a(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 3.42×10-05
Bcar3
Bcar3em1(IMPC)Mbp 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 6.01×10-05
Celf4
Celf4tm1a(EUCOMM)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 6.19×10-05
Ipo7
Ipo7em1(IMPC)Mbp 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 6.52×10-05
Cd248
Cd248tm1.1(KOMP)Vlcg 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 6.57×10-05
Prkd1
Prkd1em2(IMPC)Wtsi 		HET Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 6.83×10-05
Asf1a
Asf1atm1b(KOMP)Wtsi 		HET   Early adult increased circulating insulin level Insulin
Insulin Blood Level		 JAX
IMPC		 6.94×10-05
Rab15
Rab15tm1a(KOMP)Wtsi 		HOM Early adult decreased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 7.02×10-05
Stoml2
Stoml2tm1(KOMP)Vlcg 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 7.16×10-05
Lmod3
Lmod3em1(IMPC)Mbp 		HOM   Early adult increased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 7.95×10-05
Gcgr
Gcgrtm1.1(KOMP)Vlcg 		HOM Early adult decreased circulating insulin level Insulin
Insulin Blood Level		 UC Davis
IMPC		 8.15×10-05
Nacad
Nacadtm1(KOMP)Wtsi 		HOM Early adult increased circulating insulin level Insulin
Insulin Blood Level		 WTSI
IMPC		 9.27×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Insulin Blood Level

 Phenotype associations stats

2.23% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal circulating insulin level (67/3000)

0.37% females (11/2961) 1.77% males (52/2946)

Select a parameter    



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