Phenotype: increased circulating HDL cholesterol level

Definition
higher amount in the blood of the small lipoprotein:cholesterol complex that transports cholesterol out of the arteries and to the liver for reprocessing or excretion
Synonyms
elevated circulating HDL cholesterol level,  high HDL cholesterol level,  high HDL serum level,  increased HDL cholesterol level,  elevated HDL cholesterol level
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased circulating HDL cholesterol level

Total number of significant genotype-phenotype associations: 172

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ap2a2
Ap2a2tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 0.00
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 0.00
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 5.86×10-24
Usp47
Usp47tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 2.13×10-22
Ldlr
Ldlrtm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 2.33×10-19
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 7.61×10-16
Rxrg
RxrgRxrg
HOM Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol ICS | EuroPhenome 8.91×10-14
Cav1
Cav1em2(IMPC)Ics
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 4.61×10-12
Nr1h4
Nr1h4Nr1h4
HOM Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol ICS | EuroPhenome 1.44×10-11
Tpo
Tpoem1(IMPC)H
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.77×10-11
Tchp
Tchptm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.25×10-11
Rexo2
Rexo2tm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 3.51×10-11
Dgkk
Dgkkem1(IMPC)Ics
HEM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 5.87×10-11
Ankrd22
Ankrd22em1(IMPC)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.02×10-10
Adipor1
Adipor1tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.22×10-10
Tctn3
Tctn3em1(IMPC)J
HET Late adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.58×10-10
Cyp7a1
Cyp7a1tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 5.36×10-10
Nodal
Nodaltm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 7.96×10-10
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 9.05×10-10
Arrb2
Arrb2tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 2.83×10-09
Cdca8
Cdca8tm1a(KOMP)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | MGP 5.62×10-09
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 7.07×10-09
Ntf5
Ntf5tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.07×10-08
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.17×10-08
Usp33
Usp33tm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | MGP 1.46×10-08
Zfp644
Zfp644em1(IMPC)Ccpcz
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol CCP-IMG | IMPC 2.02×10-08
Alg8
Alg8em1(IMPC)J
HET Late adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 2.23×10-08
Lrrc3
Lrrc3tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 2.29×10-08
Reg3g
Reg3gtm1a(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.67×10-08
Gemin4
Gemin4em1(IMPC)Ics
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 2.87×10-08
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 3.31×10-08
Matn4
Matn4em1(IMPC)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.85×10-08
Rfc1
Rfc1tm1b(KOMP)Mbp
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.56×10-08
Skida1
Skida1tm1.1(KOMP)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 4.93×10-08
Hdac1
Hdac1tm1a(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol HMGU | EuroPhenome 5.79×10-08
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 5.87×10-08
Otud6a
Otud6atm1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 7.48×10-08
Trh
Trhem1(IMPC)Tcp
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 9.05×10-08
Pdzk1
Pdzk1tm2b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.07×10-07
Nat8f2
Nat8f2tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.74×10-07
Gm648
Gm648tm1e(KOMP)Wtsi
HEM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.25×10-07
Nr0b1
Nr0b1em2(IMPC)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.52×10-07
Nisch
Nischtm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.60×10-07
Hspa5
Hspa5tm1.1(KOMP)Vlcg
HET Early adult increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 2.78×10-07
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol HMGU | EuroPhenome 2.87×10-07
Abcg2
Abcg2tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 3.53×10-07
Mbd1
Mbd1em1(IMPC)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 4.15×10-07
Rnf128
Rnf128tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol CCP-IMG | IMPC 4.22×10-07
Nxn
Nxntm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol CCP-IMG | IMPC 5.25×10-07
Btbd9
Btbd9tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 6.40×10-07
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 7.29×10-07
Ampd2
Ampd2tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 8.06×10-07
Lrba
Lrbaem1(IMPC)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 8.40×10-07
Ccl9
Ccl9tm1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 8.44×10-07
Dmap1
Dmap1tm1.1(KOMP)Vlcg
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.05×10-06
D6Wsu163e
D6Wsu163etm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.18×10-06
Shh
Shhtm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.20×10-06
Sertad3
Sertad3em1(IMPC)Tcp
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 1.30×10-06
Kif18b
Kif18btm1a(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.34×10-06
Ptpn23
Ptpn23tm1b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 1.41×10-06
Cxcl9
Cxcl9tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.41×10-06
Il12a
Il12atm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.45×10-06
Rskr
Rskrtm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.80×10-06
Fgf10
Fgf10tm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.83×10-06
Aspm
Aspmtm1a(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.88×10-06
Elk3
Elk3em1(IMPC)Ics
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.96×10-06
Gins3
Gins3em1(IMPC)Tcp
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 2.06×10-06
Epas1
Epas1em1(IMPC)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.07×10-06
Map3k1
Map3k1Gt(YTC001)Byg
HET Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 2.32×10-06
Tox3
Tox3tm1b(KOMP)Mbp
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 2.42×10-06
Ankrd11
Ankrd11tm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 3.05×10-06
Casq1
Casq1tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 3.12×10-06
Tut4
Tut4tm1a(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.84×10-06
Snx15
Snx15tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.20×10-06
H3f3b
H3f3btm1.1(KOMP)Mbp
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 4.49×10-06
Slc22a8
Slc22a8tm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.82×10-06
Apoe
Apoetm1Unc
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | MGP 4.98×10-06
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 5.20×10-06
Ube2o
Ube2otm1.1(KOMP)Mbp
HET Early adult increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 5.26×10-06
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 5.34×10-06
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 6.97×10-06
Ppil3
Ppil3tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 7.93×10-06
Map3k10
Map3k10tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 8.09×10-06
Celsr1
Celsr1Scy
HET Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 9.37×10-06
Mthfsl
Mthfsltm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 9.55×10-06
Zmym4
Zmym4em1(IMPC)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 9.68×10-06
Usp12
Usp12tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 1.06×10-05
Usp11
Usp11tm1(KOMP)Wtsi
HEM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.13×10-05
Kif26b
Kif26btm2b(KOMP)Wtsi
HET Early adult increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 1.19×10-05
Rnf14
Rnf14em1(IMPC)Ccpcz
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol CCP-IMG | IMPC 1.21×10-05
Slc24a4
Slc24a4tm1b(KOMP)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.33×10-05
Brd2
Brd2em1(IMPC)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.36×10-05
Zfp174
Zfp174em1(IMPC)J
HOM Late adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 1.36×10-05
Ap2a2
Ap2a2em1(IMPC)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.47×10-05
Taf2
Taf2tm1b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 1.57×10-05
Rnf135
Rnf135em1(IMPC)Tcp
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 1.58×10-05
Kazn
Kazntm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | MGP 1.59×10-05
Pawr
Pawrtm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 1.67×10-05
BC055324
BC055324tm1a(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 1.70×10-05
Tcf7
Tcf7tm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol ICS | EuroPhenome 1.70×10-05
Dnase2b
Dnase2btm1a(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 1.70×10-05
Prkd1
Prkd1em2(IMPC)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.75×10-05
Adal
Adaltm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 1.96×10-05
Gm5155
Gm5155em1(IMPC)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.03×10-05
Grm3
Grm3tm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.07×10-05
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.15×10-05
Heyl
Heyltm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 2.16×10-05
Aqp3
Aqp3tm2b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.18×10-05
Acan
Acantm1b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.18×10-05
Nras
Nrastm1b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.20×10-05
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 2.22×10-05
Ggps1
Ggps1tm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 2.34×10-05
Arid3a
Arid3atm1b(KOMP)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 2.52×10-05
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.52×10-05
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 2.64×10-05
Aqp1
Aqp1tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 2.68×10-05
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.83×10-05
Stk16
Stk16tm1.1(KOMP)Vlcg
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 2.90×10-05
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 2.93×10-05
Aqp12
Aqp12tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 2.99×10-05
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 3.31×10-05
Bmp10
Bmp10tm3b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 3.35×10-05
Chrna7
Chrna7tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 3.46×10-05
Pfkfb3
Pfkfb3tm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 3.54×10-05
Sla2
Sla2em1(IMPC)Ccpcz
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol CCP-IMG | IMPC 3.74×10-05
Fpr3
Fpr3tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 4.03×10-05
Adora2b
Adora2btm1.1(KOMP)Vlcg
HET Early adult increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 4.09×10-05
Rhpn1
Rhpn1tm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 4.26×10-05
Cul7
Cul7tm1a(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Fasted Clinical Chemistry | HDL-cholesterol MRC Harwell | EuroPhenome 4.39×10-05
Ydjc
Ydjctm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 4.62×10-05
Tmem51
Tmem51tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.68×10-05
Zfp658
Zfp658tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 4.81×10-05
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.89×10-05
Txlna
Txlnatm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 4.92×10-05
Rhag
Rhagem1(IMPC)Ccpcz
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol CCP-IMG | IMPC 4.97×10-05
Dntt
Dntttm2b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 5.06×10-05
Exosc8
Exosc8tm1.1(KOMP)Vlcg
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 5.10×10-05
Cib2
Cib2tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 5.40×10-05
Gckr
Gckrem1(IMPC)H
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 5.41×10-05
Stag3
Stag3tm1e.1(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Plasma Chemistry | HDL cholesterol JAX | IMPC 5.84×10-05
Hook1
Hook1em1(IMPC)Tcp
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol TCP | IMPC 6.86×10-05
Dicer1
Dicer1tm1b(EUCOMM)Wtsi
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 7.05×10-05
Esr2
Esr2em1(IMPC)Marc
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MARC | IMPC 7.09×10-05
Obp2a
Obp2atm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 7.31×10-05
Runx1t1
Runx1t1tm1b(EUCOMM)Hmgu
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 7.32×10-05
Fbxw20
Fbxw20em1(IMPC)Ccpcz
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol CCP-IMG | IMPC 7.34×10-05
Dnajb3
Dnajb3tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol JAX | IMPC 7.91×10-05
Snx8
Snx8tm2a(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol WTSI | IMPC 8.00×10-05
Mocos
Mocosem2(IMPC)Ics
HET Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol ICS | IMPC 8.44×10-05
Adgrv1
Adgrv1tm1.1(KOMP)Vlcg
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 9.17×10-05
Cxcl17
Cxcl17tm1b(EUCOMM)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol UC Davis | IMPC 9.31×10-05
C4bp
C4bptm1b(KOMP)Wtsi
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol HMGU | IMPC 9.38×10-05
Mapkapk2
Mapkapk2tm1b(EUCOMM)Hmgu
HOM Early adult increased circulating HDL cholesterol level Clinical Chemistry | HDL-cholesterol MRC Harwell | IMPC 9.65×10-05

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 The way we measure

 Phenotype associations stats

3.54% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased circulating HDL cholesterol level (151/4264)

1.30% females (51/3912) 2.15% males (84/3908)

Select a parameter    



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