Definition
altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium
Synonyms
impaired proprioception
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal motor coordination/balance
Total number of significant genotype-phenotype associations: 118
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Ush1c Ush1ctm1a(KOMP)Wtsi |
HOM | Early adult | impaired righting response | Contact righting reflex Combined SHIRPA and Dysmorphology |
WTSI IMPC |
2.82×10-23 | |
| Lepr Leprtm1b(EUCOMM)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
5.41×10-22 | |
| Mir96 Mir96tm3.2(IMPC)Wtsi |
HOM | Early adult | impaired righting response | Contact righting reflex Combined SHIRPA and Dysmorphology |
WTSI IMPC |
8.76×10-21 | |
| Cyba Cybatm1a(EUCOMM)Wtsi |
HOM | Early adult | impaired righting response | Contact righting reflex Combined SHIRPA and Dysmorphology |
WTSI IMPC |
2.23×10-17 | |
| Cdh23 Cdh23tm2b(EUCOMM)Wtsi |
HOM | Early adult | impaired righting response | Contact righting reflex Combined SHIRPA and Dysmorphology |
WTSI IMPC |
2.69×10-14 | |
| Chn1 Chn1tm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.19×10-12 | |
| Prpf6 Prpf6tm1.1(KOMP)Vlcg |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
8.23×10-12 | |
| Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
ICS IMPC |
2.96×10-11 | |
| Hsd17b1 Hsd17b1tm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.26×10-11 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
CCP-IMG IMPC |
1.64×10-10 | |
| Pfdn6 Pfdn6tm1.1(KOMP)Vlcg |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.53×10-10 | |
| Vegfb Vegfbtm1b(EUCOMM)Hmgu |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.48×10-09 | |
| Myo7a Myo7atm1a(EUCOMM)Wtsi |
HOM | Early adult | impaired righting response | Contact righting reflex Combined SHIRPA and Dysmorphology |
WTSI IMPC |
1.38×10-08 | |
| Kcnj6 Kcnj6em1(IMPC)H |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
3.49×10-08 | |
| Dll1 Dll1tm1Gos |
HET | Early adult | abnormal righting response | Contact Righting Reflex Shirpa (GMC) |
HMGU EuroPhenome |
4.09×10-08 | |
| Pkp4 Pkp4tm1b(EUCOMM)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
8.87×10-08 | |
| Tpo Tpoem1(IMPC)H |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.07×10-07 | |
| Jup Juptm1.1(KOMP)Vlcg |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.15×10-07 | |
| Eogt Eogtem1(IMPC)J |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.35×10-07 | |
| Eef1b2 Eef1b2em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.74×10-07 | |
| Polr1c Polr1cem1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.74×10-07 | |
| Hapln1 Hapln1tm1.1(KOMP)Mbp |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.76×10-07 | |
| Slc8b1 Slc8b1em1(IMPC)J |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.76×10-07 | |
| Igsf11 Igsf11tm1b(KOMP)Wtsi |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.36×10-07 | |
| Srbd1 Srbd1em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.36×10-07 | |
| Utp4 Utp4em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.36×10-07 | |
| Slc24a5 Slc24a5tm1b(KOMP)Mbp |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.41×10-07 | |
| Tent5a Tent5aem1(IMPC)Ccpcz |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
CCP-IMG IMPC |
2.96×10-07 | |
| Epgn Epgntm1b(KOMP)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.15×10-07 | |
| Hecw1 Hecw1tm2b(EUCOMM)Hmgu |
HOM | Middle aged adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
3.82×10-07 | |
| Prss2 Prss2tm1.1(KOMP)Vlcg |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
7.32×10-07 | |
| AU040320 AU040320em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.02×10-06 | |
| Agbl1 Agbl1em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.02×10-06 | |
| Yeats2 Yeats2em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.02×10-06 | |
| Alg2 Alg2tm1.1(KOMP)Vlcg |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.25×10-06 | |
| Mdk Mdktm1.1(KOMP)Mbp |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.25×10-06 | |
| Catsperz Catsperztm1.1(KOMP)Vlcg |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.29×10-06 | |
| Mmaa Mmaaem1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.29×10-06 | |
| Cep43 Cep43tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal motor coordination/balance | Latency to fall_Mean Rotarod |
HMGU IMPC |
2.69×10-06 | |
| Rab3c Rab3ctm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
3.06×10-06 | |
| Rxylt1 Rxylt1em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.16×10-06 | |
| Tpk1 Tpk1em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.16×10-06 | |
| Postn Postntm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.22×10-06 | |
| Serpinb5 Serpinb5tm1b(KOMP)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.49×10-06 | |
| Mfsd4b4 Mfsd4b4em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.62×10-06 | |
| Trf Trfem1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.62×10-06 | |
| Avp Avptm1b(EUCOMM)Wtsi |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.47×10-06 | |
| Fgf7 Fgf7tm1e.1(EUCOMM)Hmgu |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.47×10-06 | |
| Gnao1 Gnao1tm1b(EUCOMM)Hmgu |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.47×10-06 | |
| Mcub Mcubtm1b(KOMP)Mbp |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.47×10-06 | |
| Ky Kyem1(IMPC)J |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.48×10-06 | |
| Arf2 Arf2tm1.1(KOMP)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.96×10-06 | |
| Myo1h Myo1htm1b(KOMP)Wtsi |
HET | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
4.98×10-06 | |
| Hsd17b1 Hsd17b1tm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
5.28×10-06 | |
| Ydjc Ydjctm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
5.64×10-06 | |
| Rnf217 Rnf217em1(IMPC)J |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
5.74×10-06 | |
| Slc20a2 Slc20a2tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal motor coordination/balance | Latency to fall_Mean Rotarod |
HMGU IMPC |
8.23×10-06 | |
| Zfp827 Zfp827em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
9.90×10-06 | |
| Epha10 Epha10tm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.11×10-05 | |
| Stat1 Stat1tm2b(EUCOMM)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
ICS IMPC |
1.12×10-05 | |
| Cdh4 Cdh4tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
1.17×10-05 | |
| Hipk4 Hipk4tm1b(KOMP)Mbp |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.30×10-05 | |
| Zfp706 Zfp706em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.30×10-05 | |
| Plod2 Plod2em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.39×10-05 | |
| Nek11 Nek11tm1b(KOMP)Wtsi |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.69×10-05 | |
| Ipp Ipptm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.77×10-05 | |
| Rnf25 Rnf25tm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.77×10-05 | |
| Mir96 Mir96tm2.2(IMPC)Wtsi |
HOM | Early adult | impaired righting response | Contact righting reflex Combined SHIRPA and Dysmorphology |
WTSI IMPC |
1.78×10-05 | |
| Abcd3 Abcd3em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.92×10-05 | |
| Fbxo10 Fbxo10em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
1.93×10-05 | |
| Cers5 Cers5tm2b(KOMP)Mbp |
HOM | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
2.07×10-05 | |
| Eefsec Eefsecem1(IMPC)Hmgu |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
HMGU IMPC |
2.19×10-05 | |
| Inhbb Inhbbtm1b(EUCOMM)Hmgu |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
2.19×10-05 | |
| Tnnc1 Tnnc1em1(IMPC)J |
HET | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.35×10-05 | |
| Svop Svopem1(IMPC)H |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
2.47×10-05 | |
| Syn3 Syn3tm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
2.48×10-05 | |
| Wars1 Wars1tm1b(EUCOMM)Hmgu |
HET | Late adult | impaired righting response | Contact righting SHIRPA |
HMGU IMPC |
2.66×10-05 | |
| Rap2b Rap2btm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
2.90×10-05 | |
| Zfp827 Zfp827em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
2.99×10-05 | |
| Idh3b Idh3bem1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.50×10-05 | |
| Samm50 Samm50em1(IMPC)Hmgu |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
HMGU IMPC |
3.85×10-05 | |
| Pcnx4 Pcnx4em1(IMPC)J |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.06×10-05 | |
| Klf7 Klf7tm1b(EUCOMM)Hmgu |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.63×10-05 | |
| Fastkd5 Fastkd5em1(IMPC)J |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.66×10-05 | |
| Zfp689 Zfp689tm1.1(KOMP)Vlcg |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.66×10-05 | |
| Lpgat1 Lpgat1em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.83×10-05 | |
| Nt5dc2 Nt5dc2em1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
4.83×10-05 | |
| Jmjd6 Jmjd6tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal motor coordination/balance | Latency to fall_Mean Rotarod |
HMGU IMPC |
4.91×10-05 | |
| Spag17 Spag17tm1b(KOMP)Wtsi |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
5.60×10-05 | |
| Pitx3 Pitx3tm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal motor coordination/balance | Average duration Rotarod |
JAX IMPC |
6.97×10-05 | |
| Gramd2b Gramd2bem1(IMPC)J |
HOM | Late adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
JAX IMPC |
8.82×10-05 | |
| Cimap1d Cimap1dtm1.1(KOMP)Vlcg |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
8.89×10-05 | |
| Grm7 Grm7em1(IMPC)H |
HOM | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
9.31×10-05 | |
| Car3 Car3em1(IMPC)Hmgu |
HET | Early adult | impaired righting response | Contact righting Combined SHIRPA and Dysmorphology |
HMGU IMPC |
9.38×10-05 |