Significant MP calls for RBRC Strains (IMPC_001)  

 

Total number of results: 742

Gene / Allele Procedure Parameter Zygosity Sex Phenotype P-value Graph
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male abnormal epididymis morphology 0.0
Twist1
Twist1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain heterozygote Male abnormal brain morphology 0.0
Cadps2
Cadps2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Female abnormal pancreas morphology 0.0
Zfhx2
Zfhx2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male abnormal epididymis morphology 0.0
Adcyap1r1
Adcyap1r1tm1e.1(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, incomplete penetrance 0.0
Ppp4r2
Ppp4r2tm2b(EUCOMM)Hmgu
Gross Pathology and Tissue Collection Kidney heterozygote Female abnormal kidney morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Stx7
Stx7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Male enlarged lymph nodes 0.0
Rlim
Rlimem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Thymus heterozygote Female enlarged thymus 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Female enlarged heart 0.0
Scube1
Scube1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Male abnormal brain morphology 0.0
Ppme1
Ppme1em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cadps2
Cadps2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Female abnormal pancreas morphology 0.0
Cnot7
Cnot7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Rlim
Rlimem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female abnormal heart morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Bone homozygote Female abnormal bone structure 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Wasf2
Wasf2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Stomach heterozygote Female abnormal stomach morphology 0.0
Penk
Penktm1(KOMP)Mbp
Gross Pathology and Tissue Collection Testes homozygote Male absent testes 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Male enlarged heart 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female abnormal heart morphology 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Male enlarged lymph nodes 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Male enlarged heart 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Rlim
Rlimem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female enlarged heart 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Kif2c
Kif2ctm1.1(KOMP)Vlcg
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Sec24d
Sec24dem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Male abnormal liver morphology 0.0
Scube1
Scube1em1(IMPC)Rbrc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Sec24d
Sec24dem1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney heterozygote Female enlarged kidney 0.0
Pals2
Pals2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Stomach homozygote Male abnormal stomach morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female abnormal heart morphology 0.0
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male small epididymis 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Female abnormal lymph node morphology 0.0
Scml2
Scml2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes hemizygote Male abnormal testis morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female enlarged heart 0.0
Twist1
Twist1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain heterozygote Female abnormal brain morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Male abnormal brain morphology 0.0
Scml2
Scml2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes hemizygote Male abnormal testis morphology 0.0
Twist1
Twist1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain heterozygote Male abnormal brain morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Bone homozygote Male abnormal bone structure 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female abnormal liver morphology 0.0
Nxn
Nxntm1b(EUCOMM)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cadps2
Cadps2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Male abnormal pancreas morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female abnormal liver morphology 0.0
Hrh1
Hrh1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Male abnormal kidney morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Male abnormal heart morphology 0.0
Agtr1a
Agtr1aem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Male abnormal kidney morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Male small liver 0.0
Ikzf4
Ikzf4em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Female abnormal kidney morphology 0.0
Wasf2
Wasf2em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cadps2
Cadps2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Male abnormal pancreas morphology 0.0
Lcmt1
Lcmt1em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female abnormal liver morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female small liver 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Scube1
Scube1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Male hydrocephaly 0.0
Rufy3
Rufy3tm1b(EUCOMM)Hmgu
Gross Pathology and Tissue Collection Stomach heterozygote Female abnormal stomach morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Eye with optic nerve homozygote Female abnormal eye morphology 0.0
Rlim
Rlimem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Thymus heterozygote Female abnormal thymus morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Male abnormal brain morphology 0.0
D1Pas1
D1Pas1tm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Eye with optic nerve homozygote Male abnormal eye morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney heterozygote Female abnormal kidney morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female small liver 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Male abnormal heart morphology 0.0
Stx7
Stx7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Thymus homozygote Male abnormal thymus morphology 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney heterozygote Female abnormal kidney morphology 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Male abnormal lymph node morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male abnormal epididymis morphology 0.0
Agtr1a
Agtr1aem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Female abnormal kidney morphology 0.0
Septin5
Septin5tm1b(EUCOMM)Hmgu
Gross Pathology and Tissue Collection Spleen heterozygote Female small spleen 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Bone homozygote Male abnormal bone structure 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female abnormal heart morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female abnormal liver morphology 0.0
Edn2
Edn2tm1b(KOMP)Mbp
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Unc5c
Unc5cem2(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Rlim
Rlimem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node heterozygote Female enlarged lymph nodes 0.0
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Scml2
Scml2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes hemizygote Male small testis 0.0
Agtr1a
Agtr1aem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Male abnormal kidney morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Female abnormal brain morphology 0.0
Scube1
Scube1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Female abnormal brain morphology 0.0
Ftl2-ps
Ftl2-psem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Female enlarged heart 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Male abnormal kidney morphology 0.0
Scml2
Scml2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes hemizygote Male small testis 0.0
Tecr
Tecrem1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Male abnormal liver morphology 0.0
Hikeshi
Hikeshiem1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Rufy3
Rufy3tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Male abnormal heart morphology 0.0
Wasf2
Wasf2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Stomach heterozygote Female abnormal stomach morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male abnormal epididymis morphology 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Female enlarged lymph nodes 0.0
Katna1
Katna1em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, incomplete penetrance 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female abnormal heart morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Ppp4r2
Ppp4r2tm2b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female small liver 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Female abnormal brain morphology 0.0
Cnot7
Cnot7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Izumo1r
Izumo1rtm1b(KOMP)Wtsi
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Female abnormal kidney morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female enlarged heart 0.0
Atp6v0a4
Atp6v0a4tm1(KOMP)Vlcg
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female enlarged heart 0.0
Scube1
Scube1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Male abnormal brain morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Male abnormal heart morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Male abnormal kidney morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Female abnormal heart morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male abnormal epididymis morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Male small liver 0.0
Cnot7
Cnot7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
D1Pas1
D1Pas1tm1(KOMP)Vlcg
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female abnormal liver morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Female abnormal brain morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Male enlarged heart 0.0
Dctn2
Dctn2tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Pomc
Pomcem1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, incomplete penetrance 0.0
Zfhx2
Zfhx2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male abnormal epididymis morphology 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Katna1
Katna1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis heterozygote Male enlarged epididymis 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney heterozygote Male abnormal kidney morphology 0.0
Scube1
Scube1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Male hydrocephaly 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Male abnormal heart morphology 0.0
Cadps2
Cadps2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Female abnormal pancreas morphology 0.0
Twist1
Twist1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain heterozygote Female abnormal brain morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Scube1
Scube1em1(IMPC)Rbrc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male small epididymis 0.0
Stx7
Stx7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Thymus homozygote Male abnormal thymus morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Cadps2
Cadps2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Male abnormal pancreas morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney heterozygote Female abnormal kidney morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney heterozygote Female enlarged kidney 0.0
Scml2
Scml2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes hemizygote Male abnormal testis morphology 0.0
Dbn1
Dbn1tm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Uterus heterozygote Female abnormal uterus morphology 0.0
Dync2h1
Dync2h1em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Stx7
Stx7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Thymus homozygote Male small thymus 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Cck
Ccktm2b(EUCOMM)Hmgu
Gross Pathology and Tissue Collection Kidney homozygote Male abnormal kidney morphology 0.0
Scml2
Scml2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes hemizygote Male small testis 0.0
Clspn
Clspntm1(KOMP)Vlcg
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Male abnormal liver morphology 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female abnormal liver morphology 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Male abnormal lymph node morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Fertility of Homozygous Knock-out Mice Gross Findings Female homozygote Female female infertility 0.0
Trpc3
Trpc3tm1b(EUCOMM)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Uterus heterozygote Female hydrometra 0.0
Ppp4r1
Ppp4r1em1(IMPC)Rbrc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
D1Pas1
D1Pas1tm1(KOMP)Vlcg
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Trf
Trfem1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Ddrgk1
Ddrgk1tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female abnormal liver morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Sec24d
Sec24dem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Stomach heterozygote Male abnormal stomach morphology 0.0
Tmed6
Tmed6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Male abnormal pancreas morphology 0.0
Septin5
Septin5tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, incomplete penetrance 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male small epididymis 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female small liver 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Uterus heterozygote Female hydrometra 0.0
Tmed6
Tmed6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Pancreas homozygote Male small pancreas 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Rlim
Rlimem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node heterozygote Female abnormal lymph node morphology 0.0
Twist1
Twist1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain heterozygote Male abnormal brain morphology 0.0
Slc2a2
Slc2a2tm1b(KOMP)Wtsi
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Female abnormal kidney morphology 0.0
Wasf2
Wasf2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Stomach heterozygote Male abnormal stomach morphology 0.0
Katna1
Katna1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes heterozygote Male enlarged testis 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Female small liver 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Cnot7
Cnot7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Wasf2
Wasf2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Stomach heterozygote Male abnormal stomach morphology 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Female abnormal lymph node morphology 0.0
Cnot7
Cnot7em1(IMPC)Rbrc
Fertility of Homozygous Knock-out Mice Gross Findings Male homozygote Male male infertility 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Male enlarged heart 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Male abnormal brain morphology 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Female abnormal lymph node morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Female abnormal kidney morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Tgm3
Tgm3tm1b(KOMP)Wtsi
Gross Pathology and Tissue Collection Kidney homozygote Female abnormal kidney morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Female small liver 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Vps11
Vps11em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Mat2a
Mat2atm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Bone homozygote Female abnormal bone structure 0.0
Psmf1
Psmf1tm1b(EUCOMM)Hmgu
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Uterus heterozygote Female abnormal uterus morphology 0.0
Ube2j2
Ube2j2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis homozygote Male small epididymis 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Wdhd1
Wdhd1em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Female enlarged lymph nodes 0.0
Agtr1a
Agtr1aem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Female abnormal kidney morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Brain homozygote Female abnormal brain morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver homozygote Male abnormal liver morphology 0.0
Cnot3
Cnot3em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney heterozygote Male abnormal kidney morphology 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Lrrc30
Lrrc30em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Lymph node homozygote Female enlarged lymph nodes 0.0
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
Gross Pathology and Tissue Collection Liver homozygote Male small liver 0.0
Ftl2-ps
Ftl2-psem1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart homozygote Female abnormal heart morphology 0.0
Tgfbr2
Tgfbr2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Heart heterozygote Female enlarged heart 0.0
Katna1
Katna1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Epididymis heterozygote Male abnormal epididymis morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Liver heterozygote Male abnormal liver morphology 0.0
Cnot7
Cnot7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male abnormal testis morphology 0.0
Fbn2
Fbn2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Kidney homozygote Male abnormal kidney morphology 0.0
Etv6
Etv6em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Gal3st1
Gal3st1em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Bone homozygote Male abnormal bone structure 0.0
Atp6v1e1
Atp6v1e1em1(IMPC)Rbrc
Viability Primary Screen Viability Outcome homozygote preweaning lethality, complete penetrance 0.0
Cnot7
Cnot7em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Testes homozygote Male small testis 0.0
Pals2
Pals2em1(IMPC)Rbrc
Gross Pathology and Tissue Collection Spleen homozygote Male abnormal spleen morphology 0.0
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Red blood cell distribution width homozygote Female increased red blood cell distribution width 0.0
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Red blood cell distribution width homozygote Male increased red blood cell distribution width 0.0
Tfr2
Tfr2em1(IMPC)Rbrc
Clinical Chemistry Iron homozygote Female increased circulating iron level 5.338947149077553E-43
Tfr2
Tfr2em1(IMPC)Rbrc
Clinical Chemistry Iron homozygote Male increased circulating iron level 3.936247386288411E-41
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Mean corpuscular hemoglobin homozygote Female decreased mean corpuscular hemoglobin 7.928804819116556E-36
Nin
Nintm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI4 homozygote Male decreased prepulse inhibition 7.357423733571505E-34
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Female decreased grip strength 3.5817477438764215E-31
Shank2
Shank2em2(IMPC)Rbrc
Open Field Periphery average speed homozygote Male hyperactivity 1.512550898999667E-30
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Hemoglobin homozygote Male decreased hemoglobin content 3.9521146986510184E-30
Shank2
Shank2em2(IMPC)Rbrc
Open Field Periphery distance travelled homozygote Male hyperactivity 4.0275332877251996E-30
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Hemoglobin homozygote Female decreased hemoglobin content 1.6505782356054237E-29
Shank2
Shank2em2(IMPC)Rbrc
Open Field Whole arena average speed homozygote Male hyperactivity 5.8170903596068735E-28
Shank2
Shank2em2(IMPC)Rbrc
Open Field Distance travelled - total homozygote Male hyperactivity 5.874625109283012E-28
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
X-ray Tibia length homozygote Female short tibia 3.059651255086928E-26
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Whole arena average speed homozygote Female hyperactivity 2.5234977500299086E-25
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Distance travelled - total homozygote Female hyperactivity 2.61640214535682E-25
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Mean corpuscular hemoglobin homozygote Male decreased mean corpuscular hemoglobin 4.8804004028287835E-25
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Periphery distance travelled homozygote Female hyperactivity 6.857804507357822E-24
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 1.370717293619521E-23
Shank2
Shank2em2(IMPC)Rbrc
Open Field Periphery average speed homozygote Female hyperactivity 1.4822839981787562E-23
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb and hindlimb grip strength normalised against body weight homozygote Male decreased grip strength 7.18343934705709E-23
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Female decreased grip strength 1.188607775461728E-22
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Periphery average speed homozygote Female hyperactivity 2.5356612298541E-22
Shank2
Shank2em2(IMPC)Rbrc
Open Field Periphery distance travelled homozygote Female hyperactivity 4.266751989093999E-22
Shank2
Shank2em2(IMPC)Rbrc
Open Field Whole arena average speed homozygote Female hyperactivity 8.603467988763178E-22
Shank2
Shank2em2(IMPC)Rbrc
Open Field Distance travelled - total homozygote Female hyperactivity 8.915750884325037E-22
Pals2
Pals2em1(IMPC)Rbrc
X-ray Tibia length homozygote Male short tibia 1.0896942357391696E-21
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Number of digits homozygote abnormal digit morphology 1.2291041582905276E-21
Twist1
Twist1em1(IMPC)Rbrc
X-ray Number of digits heterozygote abnormal digit morphology 1.2291041582905276E-21
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Number of center entries homozygote Female hyperactivity 3.391263200779469E-21
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
X-ray Tibia length homozygote Male short tibia 4.355476702338919E-21
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 4.366644448401952E-21
Pals2
Pals2em1(IMPC)Rbrc
X-ray Tibia length homozygote Female short tibia 5.569461590385304E-21
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Center average speed homozygote Female hyperactivity 1.5591716389706684E-20
Shank2
Shank2em2(IMPC)Rbrc
Open Field Whole arena resting time homozygote Male hyperactivity 1.5591873101658672E-20
Hbb-bh2
Hbb-bh2tm1b(EUCOMM)Hmgu
Hematology Red blood cell distribution width homozygote Male increased red blood cell distribution width 1.58539520309316E-20
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb and hindlimb grip strength measurement mean homozygote Male decreased grip strength 1.592730841098085E-19
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 3.8070532743416195E-19
Hbb-bh2
Hbb-bh2tm1b(EUCOMM)Hmgu
Hematology Red blood cell distribution width homozygote Female increased red blood cell distribution width 1.7103265075925915E-18
Nin
Nintm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 homozygote Male decreased prepulse inhibition 3.121865865353985E-18
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Whole arena resting time homozygote Female hyperactivity 3.6446078233356994E-18
Shank2
Shank2em2(IMPC)Rbrc
Open Field Whole arena resting time homozygote Female hyperactivity 1.775801430632313E-17
Sst
Ssttm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Fat mass homozygote Male increased total body fat amount 9.156867543393845E-17
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb grip strength normalised against body weight homozygote Female decreased grip strength 1.5473570351870773E-15
Nin
Nintm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global homozygote Male decreased prepulse inhibition 1.9014843580169184E-15
Gal3st1
Gal3st1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Gait homozygote Female abnormal gait 3.481144476955196E-15
Gal3st1
Gal3st1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Tremor homozygote Male tremors 3.481144476955196E-15
Ftl1
Ftl1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Upper teeth appearance homozygote Male abnormal tooth morphology 3.481144476955196E-15
Gal3st1
Gal3st1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Tremor homozygote Female tremors 3.481144476955196E-15
Gal3st1
Gal3st1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Gait homozygote Male abnormal gait 3.481144476955196E-15
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb digit - number heterozygote Male abnormal digit morphology 3.481144476955196E-15
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb digit - number homozygote Male abnormal digit morphology 3.481144476955196E-15
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb nail - number homozygote Male abnormal nail morphology 3.481144476955196E-15
Ftl1
Ftl1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Upper teeth appearance homozygote Female abnormal tooth morphology 3.5437872220858615E-15
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb nail - number homozygote Female abnormal nail morphology 3.5437872220858615E-15
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb digit - size heterozygote Female abnormal digit morphology 3.5437872220858615E-15
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb nail - number heterozygote Female abnormal nail morphology 3.5437872220858615E-15
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb digit - number heterozygote Female abnormal digit morphology 3.5437872220858615E-15
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindpaw - shape heterozygote Female abnormal autopod morphology 3.5437872220858615E-15
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb digit - number homozygote Female abnormal digit morphology 3.5437872220858615E-15
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindpaw - shape homozygote Female abnormal autopod morphology 3.5437872220858615E-15
Shank2
Shank2em2(IMPC)Rbrc
Open Field Center average speed homozygote Male hyperactivity 7.146705814219546E-15
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology Lymphocyte cell count homozygote Male decreased lymphocyte cell number 1.2035293788859643E-14
Kif2c
Kif2ctm1.1(KOMP)Vlcg
Combined SHIRPA and Dysmorphology Skin color - front paws heterozygote Male abnormal skin coloration 1.344848609915756E-14
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Center distance travelled homozygote Female hyperactivity 2.042810365310288E-14
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology White blood cell count homozygote Male decreased leukocyte cell number 5.750040471975276E-14
Shank2
Shank2em2(IMPC)Rbrc
Open Field Center average speed homozygote Female hyperactivity 9.741381014555586E-14
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Whole arena resting time homozygote Female hyperactivity 1.7480651258103275E-13
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb digit - size heterozygote Male abnormal digit morphology 1.969333170929316E-13
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb nail - number heterozygote Male abnormal nail morphology 1.969333170929316E-13
Fbn2
Fbn2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 3.7903239032653635E-13
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Mean cell volume homozygote Female decreased mean corpuscular volume 4.079497427800921E-13
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb digit - size homozygote Male abnormal digit morphology 1.3576463087430768E-12
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindpaw - shape homozygote Male abnormal autopod morphology 1.3576463087430768E-12
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindpaw - size heterozygote Male abnormal autopod morphology 1.3576463087430768E-12
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindpaw - shape heterozygote Male abnormal autopod morphology 1.3576463087430768E-12
Sst
Ssttm1b(KOMP)Wtsi
Clinical Chemistry Albumin homozygote Male increased circulating serum albumin level 3.0247865843990862E-12
Kif2c
Kif2ctm1.1(KOMP)Vlcg
Combined SHIRPA and Dysmorphology Skin color - front paws heterozygote Female abnormal skin coloration 4.237994937622558E-12
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology Mean corpuscular hemoglobin homozygote Male increased mean corpuscular hemoglobin 4.385392656652831E-12
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Center average speed homozygote Female hyperactivity 6.40896754069975E-12
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Mean cell volume homozygote Female increased mean corpuscular volume 6.832280834839777E-12
Rln3
Rln3tm1(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - back homozygote Female abnormal coat/hair pigmentation 1.211591677680035E-11
Rln3
Rln3tm1(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - head homozygote Female abnormal coat/hair pigmentation 1.211591677680035E-11
Rln3
Rln3tm1(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote Female abnormal coat/hair pigmentation 1.211591677680035E-11
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Body length homozygote Male decreased body length 1.462368594273844E-11
Fbn2
Fbn2em1(IMPC)Rbrc
Eye Morphology Corneal opacity homozygote Female corneal opacity 3.4885670741058306E-11
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb grip strength normalised against body weight homozygote Male decreased grip strength 3.641558929401434E-11
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 3.835800080342899E-11
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote Female increased startle reflex 4.714183210463574E-11
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Distance travelled - total homozygote Female hyperactivity 6.929966323010461E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Sacral processes homozygote Female abnormal vertebral arch morphology 6.972986077435905E-11
Runx2
Runx2em1(IMPC)Rbrc
X-ray Zygomatic bone heterozygote Female abnormal zygomatic bone morphology 6.972986077435905E-11
Twist1
Twist1em1(IMPC)Rbrc
X-ray Zygomatic bone heterozygote Female abnormal zygomatic bone morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Fibula homozygote Female abnormal fibula morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Femur homozygote Female abnormal femur morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Mandibles homozygote Female abnormal mandible morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Humerus homozygote Female abnormal humerus morphology 6.972986077435905E-11
Runx2
Runx2em1(IMPC)Rbrc
X-ray Clavicle heterozygote Female abnormal clavicle morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Clavicle homozygote Female abnormal clavicle morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Ulna homozygote Female abnormal ulna morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Zygomatic bone homozygote Female abnormal zygomatic bone morphology 6.972986077435905E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Syndactylism homozygote Female syndactyly 6.972986077435905E-11
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Whole arena average speed homozygote Female hyperactivity 6.982554812129393E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Syndactylism homozygote Male syndactyly 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Femur homozygote Male abnormal femur morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Zygomatic bone homozygote Male abnormal zygomatic bone morphology 7.09885206173766E-11
Twist1
Twist1em1(IMPC)Rbrc
X-ray Zygomatic bone heterozygote Male abnormal zygomatic bone morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Tibia homozygote Male abnormal tibia morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Sacral processes homozygote Male abnormal vertebral arch morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Lumbar processes homozygote Male abnormal vertebral arch morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Clavicle homozygote Male abnormal clavicle morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Fibula homozygote Male abnormal fibula morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Humerus homozygote Male abnormal humerus morphology 7.09885206173766E-11
Runx2
Runx2em1(IMPC)Rbrc
X-ray Zygomatic bone heterozygote Male abnormal zygomatic bone morphology 7.09885206173766E-11
Runx2
Runx2em1(IMPC)Rbrc
X-ray Clavicle heterozygote Male abnormal clavicle morphology 7.09885206173766E-11
Fbn2
Fbn2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Body length homozygote Male decreased body length 7.192049733539818E-11
Hbb-bh2
Hbb-bh2tm1b(EUCOMM)Hmgu
Hematology Mean corpuscular hemoglobin homozygote Male decreased mean corpuscular hemoglobin 1.5207592130028758E-10
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Periphery average speed homozygote Female hyperactivity 1.6147592984960824E-10
Ikzf5
Ikzf5tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 2.099179302605947E-10
Fbn2
Fbn2em1(IMPC)Rbrc
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 2.1426278806746524E-10
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Hindlimb digit - shape homozygote Female abnormal digit morphology 2.4534729803349364E-10
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Tail - morphology homozygote Female abnormal tail morphology 2.4534729803349364E-10
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Forelimb digit - size homozygote Female abnormal digit morphology 2.4534729803349364E-10
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Hindpaw - shape homozygote Female abnormal autopod morphology 2.4534729803349364E-10
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Number of center entries homozygote Female hyperactivity 2.47617565340974E-10
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Forepaw - shape homozygote Female abnormal autopod morphology 2.688139710826931E-10
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindpaw - size heterozygote Female abnormal autopod morphology 2.688139710826931E-10
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Forelimb digit - number homozygote Female abnormal digit morphology 2.688139710826931E-10
Septin5
Septin5tm1b(EUCOMM)Hmgu
Hematology Platelet count heterozygote Male thrombocytopenia 2.792811537588591E-10
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Whole arena average speed hemizygote Male hyperactivity 3.9288242104085214E-10
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Distance travelled - total hemizygote Male hyperactivity 3.9796779760514767E-10
Runx2
Runx2em1(IMPC)Rbrc
X-ray Skull shape heterozygote Female abnormal cranium morphology 4.183791646461543E-10
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Tibia homozygote Female abnormal tibia morphology 4.183791646461543E-10
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Skull shape homozygote Female abnormal cranium morphology 4.183791646461543E-10
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Radius homozygote Female abnormal radius morphology 4.183791646461543E-10
Twist1
Twist1em1(IMPC)Rbrc
X-ray Skull shape heterozygote Female abnormal cranium morphology 4.183791646461543E-10
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Mandibles homozygote Male abnormal mandible morphology 4.2593112370425956E-10
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 4.326922431463487E-10
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 4.657974006505583E-10
Sec24d
Sec24dem1(IMPC)Rbrc
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve heterozygote Male impaired glucose tolerance 5.786957579800855E-10
Sst
Ssttm1b(KOMP)Wtsi
Clinical Chemistry Iron homozygote Male increased circulating iron level 6.460386114959249E-10
Fam135b
Fam135bem1(IMPC)Rbrc
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 homozygote Male decreased prepulse inhibition 7.551204106448495E-10
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Ulna homozygote Male abnormal ulna morphology 1.490758960720484E-9
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Radius homozygote Male abnormal radius morphology 1.490758960720484E-9
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Center distance travelled homozygote Female decreased locomotor activity 1.6832759630602823E-9
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb grip strength measurement mean homozygote Female decreased grip strength 1.6984739170666785E-9
Rln3
Rln3tm1(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - back homozygote Male abnormal coat/hair pigmentation 1.708344243844806E-9
Rln3
Rln3tm1(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - head homozygote Male abnormal coat/hair pigmentation 1.708344243844806E-9
Rln3
Rln3tm1(KOMP)Mbp
Combined SHIRPA and Dysmorphology Coat - color - abdomen homozygote Male abnormal coat/hair pigmentation 1.708344243844806E-9
Nin
Nintm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI1 homozygote Male decreased prepulse inhibition 1.956704354100225E-9
Cnot3
Cnot3em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Female decreased bone mineral density 2.796253006920324E-9
Rnf10
Rnf10tm1b(KOMP)Wtsi
Hematology Mean corpuscular hemoglobin homozygote Male decreased mean corpuscular hemoglobin 2.9356581610073818E-9
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 2.9595021988626513E-9
Fbn2
Fbn2em1(IMPC)Rbrc
Eye Morphology Corneal opacity homozygote Male corneal opacity 3.525364444811885E-9
Sst
Ssttm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male increased total body fat amount 4.213217774662326E-9
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology Lymphocyte cell count homozygote Female decreased lymphocyte cell number 4.403577502642975E-9
Nin
Nintm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote Male decreased startle reflex 4.90822849030792E-9
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Percentage center movement time homozygote Male decreased anxiety-related response 5.352833731819828E-9
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Periphery average speed hemizygote Male hyperactivity 5.777637479553732E-9
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Tail - morphology homozygote Male abnormal tail morphology 6.797029161731416E-9
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Periphery permanence time homozygote Female increased thigmotaxis 7.673349067260915E-9
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Center permanence time homozygote Female increased thigmotaxis 7.673349067260915E-9
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Percentage center time homozygote Female abnormal behavior 7.673349067260915E-9
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Skull shape homozygote Male abnormal cranium morphology 8.9445535422783E-9
Runx2
Runx2em1(IMPC)Rbrc
X-ray Skull shape heterozygote Male abnormal cranium morphology 8.9445535422783E-9
Twist1
Twist1em1(IMPC)Rbrc
X-ray Skull shape heterozygote Male abnormal cranium morphology 8.9445535422783E-9
Ikzf5
Ikzf5tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 1.0308155218297088E-8
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Whole arena resting time homozygote Male hyperactivity 1.0497101854411994E-8
Prkab1
Prkab1tm1b(KOMP)Wtsi
Clinical Chemistry Total bilirubin homozygote Female increased circulating bilirubin level 1.2299618212807673E-8
Ube2j2
Ube2j2em1(IMPC)Rbrc
X-ray Tibia length homozygote Female short tibia 1.231736668216854E-8
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology White blood cell count homozygote Female decreased leukocyte cell number 1.2464050236360436E-8
Cnot7
Cnot7em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat mass homozygote Male decreased total body fat amount 1.332421195598954E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
X-ray Brachydactyly homozygote Male brachydactyly 1.4331498654485131E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
X-ray Brachydactyly homozygote Female brachydactyly 1.4331498654485131E-8
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Periphery distance travelled homozygote Female hyperactivity 1.5953435905657898E-8
Cnot3
Cnot3em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Female decreased bone mineral content 1.676742655831731E-8
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Lumbar processes homozygote Female abnormal vertebral arch morphology 1.9384900795671456E-8
Runx2
Runx2em1(IMPC)Rbrc
X-ray Humerus heterozygote Male abnormal humerus morphology 1.9663820793880404E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Tail - length homozygote Male abnormal tail length 1.9995805899952757E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Tail - length homozygote Female abnormal tail length 1.9995805899952757E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Hindlimb digit - size homozygote Female abnormal digit morphology 1.9995805899952757E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Hindlimb digit - shape homozygote Male abnormal digit morphology 1.9995805899952757E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Forelimb digit - size homozygote Male abnormal digit morphology 1.9995805899952757E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Hindpaw - shape homozygote Male abnormal autopod morphology 1.9995805899952757E-8
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Hematocrit homozygote Male decreased hematocrit 2.836451251653216E-8
Shank2
Shank2em2(IMPC)Rbrc
Open Field Periphery resting time homozygote Male hyperactivity 2.9666482603829536E-8
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Mean cell hemoglobin concentration homozygote Female decreased mean corpuscular hemoglobin concentration 3.198864462206075E-8
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Number of center entries homozygote Female decreased locomotor activity 3.266126924472701E-8
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Forepaw - shape homozygote Male abnormal autopod morphology 3.468152698360427E-8
Nlgn3
Nlgn3em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) hemizygote Male increased bone mineral density 3.5615265403521335E-8
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Percentage center movement time homozygote Female decreased anxiety-related response 3.620668920234493E-8
Etv6
Etv6em1(IMPC)Rbrc
Clinical Chemistry HDL-cholesterol heterozygote Female decreased circulating HDL cholesterol level 5.763299171235303E-8
Ftl1
Ftl1em1(IMPC)Rbrc
X-ray Tibia length homozygote Male short tibia 5.797323154865808E-8
Runx2
Runx2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Female decreased bone mineral content 5.952157522415291E-8
Cnot3
Cnot3em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Genitalia - presence heterozygote absent external male genitalia 6.183559264627547E-8
Cnot3
Cnot3em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Genitalia - morphology heterozygote abnormal male genitalia morphology 6.183559264627547E-8
Cnot3
Cnot3em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Genitalia - size heterozygote abnormal male genitalia morphology 6.183559264627547E-8
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Center distance travelled homozygote Male decreased locomotor activity 7.742250573983256E-8
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Hematocrit homozygote Female decreased hematocrit 7.929900647241084E-8
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 8.50905763627452E-8
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 8.58723083752011E-8
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Shape of ribs homozygote Female abnormal rib morphology 8.974232912350999E-8
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Whole arena resting time homozygote Female hyperactivity 9.361468755741953E-8
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
X-ray Tibia length homozygote Male short tibia 1.0343384104771758E-7
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Periphery resting time homozygote Male decreased locomotor activity 1.0518441939666445E-7
Fbn2
Fbn2em1(IMPC)Rbrc
Grip Strength Forelimb grip strength measurement mean homozygote Male decreased grip strength 1.3656722330779303E-7
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 1.4667533321244264E-7
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Number of center entries homozygote Male decreased locomotor activity 1.4989402075116232E-7
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Center average speed homozygote Female hyperactivity 1.6736504448999767E-7
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology Mean corpuscular hemoglobin homozygote Female increased mean corpuscular hemoglobin 1.732647945118515E-7
Cnot3
Cnot3em1(IMPC)Rbrc
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve heterozygote improved glucose tolerance 1.912856930630369E-7
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Mean cell volume homozygote Male decreased mean corpuscular volume 1.97777069388394E-7
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 2.0710500336917903E-7
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 2.2708948677063745E-7
Hbb-bh2
Hbb-bh2tm1b(EUCOMM)Hmgu
Hematology Mean corpuscular hemoglobin homozygote Female decreased mean corpuscular hemoglobin 2.519109330023639E-7
Sst
Ssttm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Lean mass homozygote Male decreased lean body mass 2.533406302518415E-7
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
X-ray Fusion of vertebrae homozygote vertebral fusion 2.596655690467742E-7
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 2.735929172104079E-7
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Number of center entries homozygote Male hyperactivity 2.9008921842432756E-7
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
X-ray Pelvis homozygote Male abnormal pelvic girdle bone morphology 2.956110449758853E-7
Zfhx2
Zfhx2em1(IMPC)Rbrc
Open Field Percentage center movement time homozygote Male decreased anxiety-related response 3.2975182762129407E-7
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology White blood cell count homozygote Male decreased leukocyte cell number 3.4201752896478865E-7
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology Lymphocyte cell count homozygote Male decreased lymphocyte cell number 3.7570180211332627E-7
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology Neutrophil differential count homozygote Male increased neutrophil cell number 3.758406705856032E-7
Slc5a10
Slc5a10em1(IMPC)Rbrc
Grip Strength Forelimb grip strength normalised against body weight homozygote increased grip strength 3.86764156701247E-7
Etv6
Etv6em1(IMPC)Rbrc
Clinical Chemistry Albumin heterozygote Female decreased circulating serum albumin level 4.339315466950211E-7
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Center resting time homozygote Female hyperactivity 4.567506834973756E-7
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Body length homozygote Male decreased body length 4.795552399627923E-7
Cnot7
Cnot7em1(IMPC)Rbrc
Hematology Red blood cell distribution width homozygote Male increased red blood cell distribution width 5.647904117722646E-7
Prkab1
Prkab1tm1b(KOMP)Wtsi
Hematology Mean cell hemoglobin concentration homozygote Male decreased mean corpuscular hemoglobin concentration 6.176693432280445E-7
Cnot3
Cnot3em1(IMPC)Rbrc
Clinical Chemistry Triglycerides heterozygote Male decreased circulating triglyceride level 7.170585831772769E-7
Cnot7
Cnot7em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Lean mass homozygote Male increased lean body mass 7.810724014234438E-7
Twist1
Twist1em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Male increased lean body mass 8.73377132393216E-7
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Joints homozygote abnormal joint morphology 8.777869311415998E-7
Zfhx2
Zfhx2em1(IMPC)Rbrc
Open Field Center distance travelled homozygote Male hyperactivity 9.222936796504655E-7
Fbn2
Fbn2em1(IMPC)Rbrc
Eye Morphology Optic Disc homozygote Male abnormal optic disk morphology 1.007172727440775E-6
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 1.0274119404130033E-6
Cnot7
Cnot7em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male decreased total body fat amount 1.0436762067911332E-6
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology Mean cell volume homozygote Male increased mean corpuscular volume 1.0792321063490817E-6
Nxn
Nxntm1b(EUCOMM)Wtsi
X-ray Tibia length heterozygote Male short tibia 1.208957996823301E-6
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Distance travelled - total homozygote Female hyperactivity 1.2364689609967172E-6
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Whole arena average speed homozygote Female hyperactivity 1.2394463055898086E-6
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Red blood cell count homozygote Male decreased erythrocyte cell number 1.283589313061384E-6
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male decreased bone mineral content 1.3779359733234742E-6
Nin
Nintm1b(EUCOMM)Hmgu
Auditory Brain Stem Response Click-evoked ABR threshold homozygote Male abnormal auditory brainstem response 1.4817693454460823E-6
Nin
Nintm1b(EUCOMM)Hmgu
Auditory Brain Stem Response 18kHz-evoked ABR Threshold homozygote Male abnormal auditory brainstem response 1.4817693454460823E-6
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
Auditory Brain Stem Response Click-evoked ABR threshold homozygote Male abnormal auditory brainstem response 1.4817693454460823E-6
Nin
Nintm1b(EUCOMM)Hmgu
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 homozygote Male decreased prepulse inhibition 1.496907771070255E-6
Nin
Nintm1b(EUCOMM)Hmgu
Auditory Brain Stem Response 24kHz-evoked ABR Threshold homozygote Male abnormal auditory brainstem response 1.506568878539838E-6
Nin
Nintm1b(EUCOMM)Hmgu
Auditory Brain Stem Response 30kHz-evoked ABR Threshold homozygote Male abnormal auditory brainstem response 1.5577439853586839E-6
Ikzf5
Ikzf5tm1(KOMP)Wtsi
Hematology Large Unstained Cell (LUC) count homozygote Female increased large unstained cell number 1.5583802905894117E-6
Septin5
Septin5tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) heterozygote Female decreased bone mineral content 1.5800474102434237E-6
Ppp4r2
Ppp4r2tm2b(EUCOMM)Hmgu
Open Field Periphery average speed heterozygote Male hyperactivity 1.7085645822589868E-6
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Periphery average speed homozygote hyperactivity 1.772863697624416E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 1.810816684155725E-6
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Center distance travelled homozygote Female hyperactivity 1.9307365164422663E-6
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 1.938888772201608E-6
Cnot3
Cnot3em1(IMPC)Rbrc
Open Field Number of center entries heterozygote Female decreased locomotor activity 1.95764982890978E-6
Penk
Penktm1(KOMP)Mbp
Body Composition (DEXA lean/fat) Bone Area homozygote Female abnormal bone structure 2.0089055396965705E-6
Shank2
Shank2em2(IMPC)Rbrc
Open Field Number of center entries homozygote Female hyperactivity 2.07262883122894E-6
Cnot3
Cnot3em1(IMPC)Rbrc
Open Field Center permanence time heterozygote Female increased thigmotaxis 2.075526253975113E-6
Cnot3
Cnot3em1(IMPC)Rbrc
Open Field Percentage center time heterozygote Female abnormal behavior 2.075526253975113E-6
Cnot3
Cnot3em1(IMPC)Rbrc
Open Field Periphery permanence time heterozygote Female increased thigmotaxis 2.075526253975113E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Tail - morphology homozygote abnormal tail morphology 2.0988738924643258E-6
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Male increased bone mineral content 2.35563788919535E-6
Zfhx2
Zfhx2em1(IMPC)Rbrc
X-ray Processes on vertebrae homozygote Male abnormal vertebral arch morphology 2.3886927920102607E-6
Twist1
Twist1em1(IMPC)Rbrc
X-ray Processes on vertebrae heterozygote Male abnormal vertebral arch morphology 2.3886927920102607E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
X-ray Processes on vertebrae homozygote Male abnormal vertebral arch morphology 2.3886927920102607E-6
Shank2
Shank2em2(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male increased bone mineral content 2.4240694074251223E-6
Prkab1
Prkab1tm1b(KOMP)Wtsi
Clinical Chemistry Glycosilated hemoglobin A1c (HbA1c) homozygote Female increased glycosylated hemoglobin level 2.4439464141323697E-6
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Caudal processes homozygote Male abnormal vertebral arch morphology 2.733271003307891E-6
Ikzf5
Ikzf5tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 2.9645250378962373E-6
Runx2
Runx2em1(IMPC)Rbrc
X-ray Cervical processes heterozygote Male abnormal vertebral arch morphology 3.017296194229857E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
X-ray Cervical processes homozygote Male abnormal vertebral arch morphology 3.017296194229857E-6
Zfhx2
Zfhx2em1(IMPC)Rbrc
X-ray Cervical processes homozygote Male abnormal vertebral arch morphology 3.017296194229857E-6
Twist1
Twist1em1(IMPC)Rbrc
X-ray Cervical processes heterozygote Male abnormal vertebral arch morphology 3.017296194229857E-6
Shank2
Shank2em2(IMPC)Rbrc
Open Field Percentage center time homozygote abnormal behavior 3.035468807865982E-6
Shank2
Shank2em2(IMPC)Rbrc
Open Field Center permanence time homozygote increased thigmotaxis 3.035468807865982E-6
Shank2
Shank2em2(IMPC)Rbrc
Open Field Periphery permanence time homozygote increased thigmotaxis 3.035468807865982E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
Hematology Hemoglobin homozygote Male decreased hemoglobin content 3.27845077663369E-6
Shank2
Shank2em2(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Limb grasp homozygote Female limb grasping 3.40746009896975E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Gait homozygote Female abnormal gait 3.40746009896975E-6
Ftl1
Ftl1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Unexpected behaviors homozygote Male abnormal behavior 3.40746009896975E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Skin texture - back paws homozygote Male abnormal skin morphology 3.40746009896975E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Gait homozygote Male abnormal gait 3.40746009896975E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Forelimb digit - size homozygote Male abnormal digit morphology 3.40746009896975E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Eye Morphology Retinal Blood Vessels Structure homozygote abnormal retina blood vessel morphology 3.421216888455092E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Forelimb nail - number homozygote Female abnormal nail morphology 3.4334714200667804E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Forelimb digit - size homozygote Female abnormal digit morphology 3.4334714200667804E-6
Ube2j2
Ube2j2em1(IMPC)Rbrc
Open Field Center average speed homozygote Female hyperactivity 3.4874847187893465E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Distance travelled - total homozygote Male decreased locomotor activity 3.505348786347895E-6
Rln3
Rln3tm1(KOMP)Mbp
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Female increased total body fat amount 3.5223561098973732E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Whole arena average speed homozygote Male decreased locomotor activity 3.5253301575721707E-6
Etv6
Etv6em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Female decreased bone mineral density 3.5338214274815982E-6
Rln3
Rln3tm1(KOMP)Mbp
Hematology Hemoglobin homozygote Female decreased hemoglobin content 3.707263886099099E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 3.7291040371201234E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Periphery resting time homozygote Female decreased locomotor activity 3.913155978807481E-6
Aifm3
Aifm3em1(IMPC)Rbrc
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration homozygote Female increased fasting circulating glucose level 3.954674411943415E-6
Shank2
Shank2em2(IMPC)Rbrc
Hematology Red blood cell count homozygote Male decreased erythrocyte cell number 3.964580173487775E-6
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology Lymphocyte differential count homozygote Male decreased lymphocyte cell number 4.145927505305735E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Male increased bone mineral content 4.185543275525561E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Eye Morphology Corneal vascularization homozygote Female corneal vascularization 4.318609626352554E-6
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Heart Weight Heart weight homozygote Male decreased heart weight 4.332144271756988E-6
Ftl1
Ftl1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Gait homozygote abnormal gait 4.4128978515800554E-6
Twist1
Twist1em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Hindlimb nail - length heterozygote abnormal nail morphology 4.429677119333064E-6
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male decreased bone mineral content 4.600402917276369E-6
Runx2
Runx2em1(IMPC)Rbrc
X-ray Pelvis heterozygote Male abnormal pelvic girdle bone morphology 4.669625013775658E-6
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Pelvis homozygote Male abnormal pelvic girdle bone morphology 4.669625013775658E-6
Twist1
Twist1em1(IMPC)Rbrc
X-ray Pelvis heterozygote Male abnormal pelvic girdle bone morphology 4.669625013775658E-6
Ttc5
Ttc5em1(IMPC)Rbrc
Grip Strength Forelimb grip strength normalised against body weight heterozygote increased grip strength 4.677333436120534E-6
Sst
Ssttm1b(KOMP)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Male decreased circulating alkaline phosphatase level 4.8667484406905714E-6
Shank2
Shank2em2(IMPC)Rbrc
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female increased bone mineral content 4.922143943986157E-6
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male decreased bone mineral content 4.937704034091439E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
Hematology Mean corpuscular hemoglobin homozygote Female decreased mean corpuscular hemoglobin 5.0300009206694085E-6
Penk
Penktm1(KOMP)Mbp
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 5.067734036856564E-6
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Whole arena average speed homozygote Male hyperactivity 5.071488430985482E-6
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Distance travelled - total homozygote Male hyperactivity 5.110182428325061E-6
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Fusion of vertebrae homozygote vertebral fusion 5.2329705795273185E-6
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Periphery resting time homozygote Female hyperactivity 5.289040018396918E-6
Sst
Ssttm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male decreased bone mineral content 5.412754944700282E-6
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Periphery distance travelled hemizygote Male hyperactivity 5.414885890786536E-6
Rln3
Rln3tm1(KOMP)Mbp
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 5.576220246439334E-6
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
X-ray Fusion of processes homozygote fusion of vertebral arches 5.6978879001690075E-6
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Mean cell hemoglobin concentration homozygote Female increased mean corpuscular hemoglobin concentration 5.7747820392251015E-6
Kif2c
Kif2ctm1.1(KOMP)Vlcg
Combined SHIRPA and Dysmorphology Skin color - back paws heterozygote Female abnormal skin coloration 6.005927843943937E-6
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Gait homozygote Female abnormal gait 6.005927843943937E-6
Fbn2
Fbn2em1(IMPC)Rbrc
Hematology Platelet count homozygote Male thrombocytopenia 6.126791959104594E-6
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Periphery distance travelled homozygote hyperactivity 6.16895249549998E-6
Cnot7
Cnot7em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Male increased bone mineral content 6.204753390193218E-6
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology Red blood cell count homozygote Female decreased erythrocyte cell number 6.509230843221303E-6
Septin5
Septin5tm1b(EUCOMM)Hmgu
X-ray Tibia length heterozygote Female short tibia 6.677754299744265E-6
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
X-ray Pelvis homozygote Female abnormal pelvic girdle bone morphology 6.80774837746867E-6
Dbn1
Dbn1tm1b(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Locomotor activity heterozygote increased exploration in new environment 6.864087481517345E-6
Nin
Nintm1b(EUCOMM)Hmgu
Auditory Brain Stem Response 12kHz-evoked ABR Threshold homozygote Male abnormal auditory brainstem response 7.0631008384225424E-6
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
Auditory Brain Stem Response 12kHz-evoked ABR Threshold homozygote Male abnormal auditory brainstem response 7.0631008384225424E-6
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Periphery distance travelled homozygote decreased locomotor activity 7.0772794060758315E-6
Etv6
Etv6em1(IMPC)Rbrc
Clinical Chemistry Total protein heterozygote Female decreased circulating total protein level 7.224130968097597E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve homozygote Male improved glucose tolerance 7.289328550541541E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Periphery average speed homozygote Male decreased locomotor activity 7.348642157012364E-6
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Red blood cell count homozygote Female decreased erythrocyte cell number 7.477812687284313E-6
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Hematology White blood cell count homozygote Male increased leukocyte cell number 8.110053386189975E-6
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Open Field Latency to center entry homozygote Male decreased exploration in new environment 8.170786713890266E-6
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat mass homozygote Male increased total body fat amount 8.243774573202245E-6
Runx2
Runx2em1(IMPC)Rbrc
X-ray Processes on vertebrae heterozygote Female abnormal vertebral arch morphology 8.28076917969156E-6
Zfhx2
Zfhx2em1(IMPC)Rbrc
X-ray Processes on vertebrae homozygote Female abnormal vertebral arch morphology 8.28076917969156E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
X-ray Processes on vertebrae homozygote Female abnormal vertebral arch morphology 8.28076917969156E-6
Twist1
Twist1em1(IMPC)Rbrc
X-ray Processes on vertebrae heterozygote Female abnormal vertebral arch morphology 8.28076917969156E-6
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Percentage center movement time homozygote Female decreased anxiety-related response 8.369566785404459E-6
Cnot3
Cnot3em1(IMPC)Rbrc
Y-maze Total arm entries heterozygote decreased locomotor activity 8.373172931896988E-6
Ppp4r1
Ppp4r1em1(IMPC)Rbrc
Hematology Platelet count homozygote Male thrombocytosis 8.444640116067603E-6
Ppp4r2
Ppp4r2tm2b(EUCOMM)Hmgu
Open Field Distance travelled - total heterozygote Male hyperactivity 8.731158231967129E-6
Ppp4r2
Ppp4r2tm2b(EUCOMM)Hmgu
Open Field Whole arena average speed heterozygote Male hyperactivity 8.7548432929907E-6
Rln3
Rln3tm1(KOMP)Mbp
Clinical Chemistry Iron homozygote Female increased circulating iron level 8.805333891359624E-6
Penk
Penktm1(KOMP)Mbp
Open Field Periphery resting time homozygote decreased locomotor activity 9.146600859821774E-6
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Center distance travelled homozygote Male hyperactivity 9.442601367481984E-6
Cnot3
Cnot3em1(IMPC)Rbrc
Clinical Chemistry Total bilirubin heterozygote Male increased circulating bilirubin level 9.669183782534674E-6
Twist1
Twist1em1(IMPC)Rbrc
X-ray Cervical processes heterozygote Female abnormal vertebral arch morphology 9.936923561326694E-6
Runx2
Runx2em1(IMPC)Rbrc
X-ray Cervical processes heterozygote Female abnormal vertebral arch morphology 9.936923561326694E-6
Gal3st1
Gal3st1em1(IMPC)Rbrc
X-ray Cervical processes homozygote Female abnormal vertebral arch morphology 9.936923561326694E-6
Zfhx2
Zfhx2em1(IMPC)Rbrc
X-ray Cervical processes homozygote Female abnormal vertebral arch morphology 9.936923561326694E-6
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Periphery average speed homozygote Male hyperactivity 9.945680176315363E-6
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Indirect Calorimetry Total water intake homozygote Male increased fluid intake 1.0269612175761722E-5
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Center distance travelled hemizygote Male hyperactivity 1.0557189852988813E-5
Ftl1
Ftl1em1(IMPC)Rbrc
X-ray Tibia length homozygote Female short tibia 1.106534637074219E-5
Rnf10
Rnf10tm1b(KOMP)Wtsi
Hematology Mean cell volume homozygote Male decreased mean corpuscular volume 1.1110402738268021E-5
Slc2a2
Slc2a2tm1b(KOMP)Wtsi
Clinical Chemistry Glycosilated hemoglobin A1c (HbA1c) heterozygote Male increased glycosylated hemoglobin level 1.1186608389834873E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Whole arena resting time homozygote Female decreased locomotor activity 1.133670230046846E-5
Ppme1
Ppme1em1(IMPC)Rbrc
Clinical Chemistry Triglycerides heterozygote Male increased circulating triglyceride level 1.1679996532620862E-5
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology Platelet count homozygote Female thrombocytopenia 1.2131402399973013E-5
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
Auditory Brain Stem Response 6kHz-evoked ABR Threshold homozygote Male abnormal auditory brainstem response 1.2842001524404623E-5
Twist1
Twist1em1(IMPC)Rbrc
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI4 heterozygote Male decreased prepulse inhibition 1.327909376414027E-5
Etv6
Etv6em1(IMPC)Rbrc
Hematology Large Unstained Cell (LUC) count heterozygote increased large unstained cell number 1.348152454738738E-5
Fbn2
Fbn2em1(IMPC)Rbrc
Combined SHIRPA and Dysmorphology Skin texture - back paws homozygote Female abnormal skin morphology 1.3628779015562031E-5
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 1.3851570656697731E-5
Twist1
Twist1em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat/Body weight heterozygote Male decreased total body fat amount 1.386034728056984E-5
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology Red blood cell count homozygote Male decreased erythrocyte cell number 1.4304384421848226E-5
Ube2j2
Ube2j2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Lean mass homozygote decreased lean body mass 1.500848065916216E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Fat/Body weight homozygote Male decreased total body fat amount 1.619533031771425E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Body Composition (DEXA lean/fat) Fat mass homozygote increased total body fat amount 1.626483935979195E-5
Fbn2
Fbn2em1(IMPC)Rbrc
Electrocardiogram (ECG) ST homozygote prolonged ST segment 1.6499674529768527E-5
Oxtr
Oxtrtm1.1(KOMP)Vlcg
Clinical Chemistry LDL-cholesterol homozygote increased circulating LDL cholesterol level 1.699115091469139E-5
Diaph1
Diaph1em1(IMPC)Rbrc
Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) homozygote increased blood urea nitrogen level 1.7119627955253236E-5
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
X-ray Joints homozygote abnormal joint morphology 1.7202264643856324E-5
Zfhx2
Zfhx2em1(IMPC)Rbrc
Open Field Periphery resting time homozygote hyperactivity 1.732847886160016E-5
Septin5
Septin5tm1b(EUCOMM)Hmgu
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve heterozygote improved glucose tolerance 1.7428741557523608E-5
Rln3
Rln3tm1(KOMP)Mbp
Hematology Red blood cell count homozygote Female decreased erythrocyte cell number 1.8033924789051525E-5
Trf
Trfem1(IMPC)Rbrc
Clinical Chemistry Iron heterozygote Male decreased circulating iron level 1.8281252778251655E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Hematology Lymphocyte cell count homozygote Male increased lymphocyte cell number 1.8488204659661278E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 1.8567443476058543E-5
Wdhd1
Wdhd1em1(IMPC)Rbrc
Clinical Chemistry Aspartate aminotransferase heterozygote Male increased circulating aspartate transaminase level 1.903011798276566E-5
Fbn2
Fbn2em1(IMPC)Rbrc
Clinical Chemistry Alpha-amylase homozygote decreased circulating amylase level 1.9307519323774613E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Percentage center movement time homozygote Male decreased anxiety-related response 1.977075226022862E-5
Unc5c
Unc5cem2(IMPC)Rbrc
Open Field Whole arena resting time heterozygote decreased locomotor activity 2.205182499892544E-5
Sst
Ssttm1b(KOMP)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Female decreased circulating alkaline phosphatase level 2.213092739111744E-5
Twist1
Twist1em1(IMPC)Rbrc
X-ray Pelvis heterozygote Female abnormal pelvic girdle bone morphology 2.2636542780674063E-5
Runx2
Runx2em1(IMPC)Rbrc
X-ray Pelvis heterozygote Female abnormal pelvic girdle bone morphology 2.2636542780674063E-5
Fbn2
Fbn2em1(IMPC)Rbrc
X-ray Pelvis homozygote Female abnormal pelvic girdle bone morphology 2.2636542780674063E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Clinical Chemistry Total cholesterol homozygote increased circulating cholesterol level 2.2763570086681284E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote Female increased circulating alkaline phosphatase level 2.283134926983621E-5
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Periphery resting time homozygote Male hyperactivity 2.288144787598867E-5
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Number of center entries hemizygote Male hyperactivity 2.375525946263224E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 2.4991231839521788E-5
Septin5
Septin5tm1b(EUCOMM)Hmgu
Hematology Platelet count heterozygote Female thrombocytopenia 2.516020686016418E-5
Etv6
Etv6em1(IMPC)Rbrc
Clinical Chemistry Total cholesterol heterozygote Female decreased circulating cholesterol level 2.5290641133324243E-5
Etv6
Etv6em1(IMPC)Rbrc
Clinical Chemistry Uric acid heterozygote Female increased blood uric acid level 2.5913801437127404E-5
Ikzf4
Ikzf4em1(IMPC)Rbrc
Open Field Center resting time homozygote Female decreased locomotor activity 2.640918319229968E-5
Gypc
Gypcem1(IMPC)Rbrc
Clinical Chemistry Glycosilated hemoglobin A1c (HbA1c) homozygote Female decreased glycosylated hemoglobin level 2.6432351660332642E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 2.6436384359840304E-5
Tfr2
Tfr2em1(IMPC)Rbrc
Hematology Hemoglobin homozygote increased hemoglobin content 2.6712972612585872E-5
Septin5
Septin5tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Area heterozygote Female abnormal bone structure 2.8047867090208456E-5
Kif2c
Kif2ctm1.1(KOMP)Vlcg
Clinical Chemistry Triglycerides heterozygote Male increased circulating triglyceride level 2.8491362172644585E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote decreased bone mineral content 2.8658436349360272E-5
Trf
Trfem1(IMPC)Rbrc
Clinical Chemistry Iron heterozygote Female decreased circulating iron level 2.9948432711535133E-5
Prkab1
Prkab1tm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 3.0456591048277915E-5
Shank2
Shank2em2(IMPC)Rbrc
Open Field Center resting time homozygote Female hyperactivity 3.108620876446366E-5
Rnf10
Rnf10tm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Male increased bone mineral content 3.117442611255683E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Body Composition (DEXA lean/fat) Lean mass homozygote decreased lean body mass 3.139554974040948E-5
Runx2
Runx2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Area heterozygote Female abnormal bone structure 3.171585558447987E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
X-ray Tibia length homozygote Female short tibia 3.3069922210415825E-5
Ikzf3
Ikzf3tm1(KOMP)Vlcg
Hematology Large Unstained Cell (LUC) count homozygote Male decreased large unstained cell number 3.3246225939365104E-5
Dbn1
Dbn1tm1b(KOMP)Wtsi
Clinical Chemistry Alkaline phosphatase heterozygote Female increased circulating alkaline phosphatase level 3.325464058434591E-5
Atp6v1g2
Atp6v1g2em1(IMPC)Rbrc
Open Field Whole arena resting time homozygote hyperactivity 3.345571531099267E-5
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
X-ray Tibia length homozygote Female short tibia 3.4198787034256384E-5
Tmem63c
Tmem63cem1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat mass homozygote Male increased total body fat amount 3.425738759688102E-5
Rlim
Rlimem1(IMPC)Rbrc
X-ray Fusion of processes hemizygote Male fusion of vertebral arches 3.454784018686041E-5
Hbq1a
Hbq1atm1.1(KOMP)Vlcg
Hematology Red blood cell count homozygote increased erythrocyte cell number 3.519946039887145E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Indirect Calorimetry Respiratory Exchange Ratio homozygote Female decreased respiratory quotient 3.6441000702325255E-5
Ube2j2
Ube2j2em1(IMPC)Rbrc
Open Field Whole arena resting time homozygote Female hyperactivity 3.6782646930078045E-5
Pomc
Pomcem1(IMPC)Rbrc
Intraperitoneal glucose tolerance test (IPGTT) Area under glucose response curve heterozygote Male impaired glucose tolerance 3.6982251913286746E-5
Fam135b
Fam135bem1(IMPC)Rbrc
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global homozygote decreased prepulse inhibition 3.724996349774301E-5
Prkab1
Prkab1tm1b(KOMP)Wtsi
Clinical Chemistry Alkaline phosphatase homozygote increased circulating alkaline phosphatase level 3.7943493225611746E-5
Tecr
Tecrem1(IMPC)Rbrc
Clinical Chemistry LDL-cholesterol heterozygote Male increased circulating LDL cholesterol level 3.8024780224077404E-5
Ttc5
Ttc5em1(IMPC)Rbrc
Grip Strength Forelimb grip strength measurement mean heterozygote increased grip strength 3.9323138480540365E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Female decreased bone mineral density 3.936115535907447E-5
Stx7
Stx7em1(IMPC)Rbrc
Hematology Large Unstained Cell (LUC) differential count homozygote decreased large unstained cell number 3.987849413533695E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote Male decreased bone mineral density 4.002551213488914E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
X-ray Tibia length homozygote Male short tibia 4.0311588236363605E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Center average speed homozygote Male hyperactivity 4.052327130921185E-5
Ptprm
Ptprmem1(IMPC)Rbrc
Clinical Chemistry Creatine kinase homozygote Male increased circulating creatine kinase level 4.1237217374145985E-5
Ube2j2
Ube2j2em1(IMPC)Rbrc
X-ray Tibia length homozygote Male short tibia 4.2313829908380285E-5
Ppp4r1
Ppp4r1em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) homozygote increased bone mineral density 4.262800939613953E-5
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat/Body weight homozygote increased total body fat amount 4.296024053473957E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Clinical Chemistry Lactate dehydrogenase homozygote Male increased circulating lactate dehydrogenase level 4.3025356717407703E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI1 homozygote increased prepulse inhibition 4.333898687036708E-5
Runx2
Runx2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Lean/Body weight heterozygote Female increased lean body mass 4.393661947688088E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global homozygote increased prepulse inhibition 4.419680408318527E-5
Prkab1
Prkab1tm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote Female decreased bone mineral content 4.4505544792627916E-5
Pals2
Pals2em1(IMPC)Rbrc
X-ray Fusion of processes homozygote fusion of vertebral arches 4.4901767978444695E-5
Wdhd1
Wdhd1em1(IMPC)Rbrc
Clinical Chemistry Total bilirubin heterozygote increased circulating bilirubin level 4.5039429096505046E-5
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Combined SHIRPA and Dysmorphology Hindlimb digit - size homozygote Male abnormal digit morphology 4.5090542698744684E-5
Twist1
Twist1em1(IMPC)Rbrc
Grip Strength Forelimb grip strength normalised against body weight heterozygote Female increased grip strength 4.528945282800123E-5
Gal3st1
Gal3st1em1(IMPC)Rbrc
X-ray Tibia length homozygote Female short tibia 4.652858478948474E-5
Septin5
Septin5tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) heterozygote Female decreased bone mineral density 4.748718492919579E-5
Penk
Penktm1(KOMP)Mbp
Eye Morphology Retina (combined) homozygote abnormal retina morphology 4.771541352965869E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Indirect Calorimetry Respiratory Exchange Ratio homozygote decreased respiratory quotient 4.851210906053893E-5
Etv6
Etv6em1(IMPC)Rbrc
Hematology Platelet count heterozygote thrombocytopenia 4.884684312855825E-5
Ikzf4
Ikzf4em1(IMPC)Rbrc
Open Field Periphery permanence time homozygote decreased thigmotaxis 4.9221780500374734E-5
Ikzf4
Ikzf4em1(IMPC)Rbrc
Open Field Center permanence time homozygote decreased thigmotaxis 4.9221780500374734E-5
Ikzf4
Ikzf4em1(IMPC)Rbrc
Open Field Percentage center time homozygote abnormal behavior 4.9221780500374734E-5
Stx7
Stx7em1(IMPC)Rbrc
Hematology Large Unstained Cell (LUC) count homozygote decreased large unstained cell number 4.9848655180539936E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Hematology Hematocrit homozygote Male increased hematocrit 5.169091673451476E-5
Cnot3
Cnot3em1(IMPC)Rbrc
Open Field Center resting time heterozygote Female hyperactivity 5.189068542676978E-5
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 5.2543186029652134E-5
Cnot3
Cnot3em1(IMPC)Rbrc
Open Field Center distance travelled heterozygote Female decreased locomotor activity 5.374754255171865E-5
Nin
Nintm1b(EUCOMM)Hmgu
Open Field Center average speed homozygote Male hyperactivity 5.509674519998953E-5
Nlgn3
Nlgn3em1(IMPC)Rbrc
Open Field Whole arena resting time hemizygote Male hyperactivity 5.5278604122577235E-5
Gal3st1
Gal3st1em1(IMPC)Rbrc
Open Field Percentage center movement time homozygote Male increased anxiety-related response 5.567768312175758E-5
Tmed6
Tmed6em1(IMPC)Rbrc
Y-maze Latency to leave start arm homozygote Female decreased exploration in new environment 5.586039333138615E-5
Ppp4r2
Ppp4r2tm2b(EUCOMM)Hmgu
Combined SHIRPA and Dysmorphology Locomotor activity heterozygote increased exploration in new environment 5.643313124892302E-5
Etv6
Etv6em1(IMPC)Rbrc
Clinical Chemistry Calcium heterozygote Female decreased circulating calcium level 5.668835365213454E-5
Fbn2
Fbn2em1(IMPC)Rbrc
Eye Morphology Pupil Position homozygote abnormal placement of pupils 5.7709428801899776E-5
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) BMC/Body weight homozygote Female decreased bone mineral content 5.8355421060696244E-5
Aifm3
Aifm3em1(IMPC)Rbrc
Clinical Chemistry Aspartate aminotransferase homozygote Female increased circulating aspartate transaminase level 6.051471063983627E-5
Fbn2
Fbn2em1(IMPC)Rbrc
Open Field Percentage center movement time homozygote decreased anxiety-related response 6.174235022626817E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Center permanence time homozygote Male decreased thigmotaxis 6.320057582342997E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Percentage center time homozygote Male abnormal behavior 6.320057582342997E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Periphery permanence time homozygote Male decreased thigmotaxis 6.320057582342997E-5
Penk
Penktm1(KOMP)Mbp
Body Composition (DEXA lean/fat) Body length homozygote Female decreased body length 6.42131781205535E-5
Fam135b
Fam135bem1(IMPC)Rbrc
Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 homozygote decreased prepulse inhibition 6.571877020178363E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
Clinical Chemistry Albumin homozygote decreased circulating serum albumin level 6.989878602325916E-5
Etv6
Etv6em1(IMPC)Rbrc
Hematology Red blood cell count heterozygote decreased erythrocyte cell number 6.993179704295471E-5
Prkab1
Prkab1tm1b(KOMP)Wtsi
Clinical Chemistry Alpha-amylase homozygote decreased circulating amylase level 7.03254045220092E-5
Pals2
Pals2em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 7.178218947956339E-5
Ube2j1
Ube2j1tm1.1(NCOM)Mfgc
Clinical Chemistry Alpha-amylase homozygote Female increased circulating amylase level 7.523662497987971E-5
Septin5
Septin5tm1b(EUCOMM)Hmgu
X-ray Tibia length heterozygote Male short tibia 7.545624976046383E-5
Sst
Ssttm1b(KOMP)Wtsi
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Male decreased lean body mass 7.585869025206193E-5
Dnase1l2
Dnase1l2tm1(KOMP)Wtsi
Heart Weight Heart weight homozygote Male increased heart weight 7.618608651682734E-5
Septin5
Septin5tm1b(EUCOMM)Hmgu
Body Composition (DEXA lean/fat) Body length heterozygote Female decreased body length 7.695220847381279E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Lean/Body weight homozygote Male increased lean body mass 8.137524855555966E-5
Ftl1
Ftl1em1(IMPC)Rbrc
Hematology Red blood cell distribution width homozygote increased red blood cell distribution width 8.345740934601054E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Open Field Number of center entries homozygote hyperactivity 8.44671594677493E-5
Penk
Penktm1(KOMP)Mbp
Body Composition (DEXA lean/fat) Fat mass homozygote Female increased total body fat amount 8.4793267888017E-5
Ube2j2
Ube2j2em1(IMPC)Rbrc
Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S homozygote increased startle reflex 8.482090925099328E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Whole arena average speed homozygote Female decreased locomotor activity 8.491763583151624E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
Clinical Chemistry Creatine kinase homozygote Male increased circulating creatine kinase level 8.503966819262132E-5
Cadps2
Cadps2em1(IMPC)Rbrc
Clinical Chemistry Alpha-amylase homozygote increased circulating amylase level 8.540787530364469E-5
Cnot7
Cnot7em1(IMPC)Rbrc
Open Field Distance travelled - total homozygote Female decreased locomotor activity 8.626346971141174E-5
Rnf10
Rnf10tm1b(KOMP)Wtsi
Hematology Hemoglobin homozygote Female decreased hemoglobin content 8.74840043252334E-5
Twist1
Twist1em1(IMPC)Rbrc
X-ray Shape of vertebrae heterozygote abnormal vertebrae morphology 8.786158286966383E-5
Runx2
Runx2em1(IMPC)Rbrc
X-ray Shape of vertebrae heterozygote abnormal vertebrae morphology 8.786158286966383E-5
Slc2a2
Slc2a2tm1b(KOMP)Wtsi
Intraperitoneal glucose tolerance test (IPGTT) Fasted blood glucose concentration heterozygote Male increased fasting circulating glucose level 9.085791680263355E-5
Zfhx2
Zfhx2em1(IMPC)Rbrc
Open Field Periphery permanence time homozygote decreased thigmotaxis 9.22720500966534E-5
Ppp4r1
Ppp4r1em1(IMPC)Rbrc
Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) homozygote increased bone mineral content 9.385932207806036E-5
Hbq1a
Hbq1atm1.1(KOMP)Vlcg
Hematology Mean corpuscular hemoglobin homozygote Male decreased mean corpuscular hemoglobin 9.446012700209394E-5
Npsr1
Npsr1tm1b(KOMP)Wtsi
Hematology Eosinophil cell count homozygote Female increased eosinophil cell number 9.44971470744349E-5
Ube2j2
Ube2j2em1(IMPC)Rbrc
Hematology Eosinophil differential count homozygote Female increased eosinophil cell number 9.56714793574065E-5

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