Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data abnormal heart morphology Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_006_002 preweaning lethality, incomplete penetrance Ppp2r5c homozygote female Early adult Viability Primary Screen Homozygous females viability UC Davis IMPC 0.0 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_VIA_064_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_VIA_002¶meter_stable_id=IMPC_VIA_064_001&phenotyping_center=UC Davis enlarged lymph nodes Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Lymph node UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_020_002 enlarged spleen Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_016_002 enlarged spleen Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_016_002 abnormal spleen morphology Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_016_002 abnormal heart morphology Ppp2r5c homozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_006_002 abnormal lymph node morphology Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Lymph node UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_020_002 enlarged heart Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_006_002 enlarged lymph nodes Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Lymph node UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_020_002 abnormal lymph node morphology Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Lymph node UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_020_002 abnormal spleen morphology Ppp2r5c homozygote male Early adult Gross Pathology and Tissue Collection Spleen UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_016_002 enlarged heart Ppp2r5c homozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //dev.mousephenotype.org/data/grosspath/MGI:1349475/IMPC_PAT_006_002 decreased grip strength Ppp2r5c homozygote male Early adult Grip Strength Forelimb and hindlimb grip strength measurement mean UC Davis IMPC 1.68E-15 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_GRS_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_009_001&phenotyping_center=UC Davis irregularly shaped pupil Ppp2r5c homozygote male Early adult Eye Morphology Pupil Shape UC Davis IMPC 6.17E-15 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_EYE_012_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_012_001&phenotyping_center=UC Davis irregularly shaped pupil Ppp2r5c homozygote female Early adult Eye Morphology Pupil Shape UC Davis IMPC 1.22E-14 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_EYE_012_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_012_001&phenotyping_center=UC Davis abnormal placement of pupils Ppp2r5c homozygote male Early adult Eye Morphology Pupil Position UC Davis IMPC 3.65E-11 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_EYE_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_011_001&phenotyping_center=UC Davis abnormal placement of pupils Ppp2r5c homozygote female Early adult Eye Morphology Pupil Position UC Davis IMPC 7.88E-11 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_EYE_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_EYE_003¶meter_stable_id=IMPC_EYE_011_001&phenotyping_center=UC Davis decreased grip strength Ppp2r5c homozygote male Early adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight UC Davis IMPC 1.55E-10 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_GRS_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_011_001&phenotyping_center=UC Davis increased mean corpuscular volume Ppp2r5c homozygote female Early adult Hematology Mean cell volume UC Davis IMPC 4.39E-10 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_HEM_005_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_005_001&phenotyping_center=UC Davis decreased startle reflex Ppp2r5c homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) Response amplitude - S UC Davis IMPC 7.17E-10 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_ACS_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_006_001&phenotyping_center=UC Davis increased heart weight Ppp2r5c homozygote male Early adult Heart Weight Heart weight UC Davis IMPC 3.08E-8 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_HWT_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HWT_001¶meter_stable_id=IMPC_HWT_008_001&phenotyping_center=UC Davis increased heart weight Ppp2r5c homozygote male Early adult Organ Weight Heart weight UC Davis IMPC 3.08E-8 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=UCD_OWT_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=UCD_OWT_001¶meter_stable_id=UCD_OWT_002_001&phenotyping_center=UC Davis decreased grip strength Ppp2r5c homozygote female Early adult Grip Strength Forelimb and hindlimb grip strength normalised against body weight UC Davis IMPC 3.65E-8 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_GRS_011_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_011_001&phenotyping_center=UC Davis increased mean corpuscular volume Ppp2r5c homozygote male Early adult Hematology Mean cell volume UC Davis IMPC 1.26E-7 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_HEM_005_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_005_001&phenotyping_center=UC Davis shortened ST segment Ppp2r5c homozygote male Early adult Electrocardiogram (ECG) ST UC Davis IMPC 2.47E-6 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_ECG_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ECG_003¶meter_stable_id=IMPC_ECG_008_001&phenotyping_center=UC Davis decreased exploration in new environment Ppp2r5c homozygote male Early adult Light-Dark Test Latency to first transition into dark UC Davis IMPC 8.63E-6 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_LDT_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_LDT_001¶meter_stable_id=IMPC_LDT_006_001&phenotyping_center=UC Davis increased total body fat amount Ppp2r5c homozygote female Early adult Body Composition (DEXA lean/fat) Fat/Body weight UC Davis IMPC 1.11E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_DXA_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_009_001&phenotyping_center=UC Davis decreased lean body mass Ppp2r5c homozygote female Early adult Body Composition (DEXA lean/fat) Lean/Body weight UC Davis IMPC 1.25E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_DXA_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_008_001&phenotyping_center=UC Davis decreased grip strength Ppp2r5c homozygote female Early adult Grip Strength Forelimb and hindlimb grip strength measurement mean UC Davis IMPC 1.26E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_GRS_009_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_GRS_001¶meter_stable_id=IMPC_GRS_009_001&phenotyping_center=UC Davis increased mean corpuscular hemoglobin Ppp2r5c homozygote female Early adult Hematology Mean corpuscular hemoglobin UC Davis IMPC 2.79E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_HEM_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_006_001&phenotyping_center=UC Davis decreased exploration in new environment Ppp2r5c homozygote not_considered Early adult Combined SHIRPA and Dysmorphology Locomotor activity UC Davis IMPC 3.42E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_CSD_032_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_032_001&phenotyping_center=UC Davis increased neutrophil cell number Ppp2r5c homozygote female Early adult Hematology Neutrophil cell count UC Davis IMPC 5.5E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_HEM_030_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_030_001&phenotyping_center=UC Davis increased blood urea nitrogen level Ppp2r5c homozygote male Early adult Clinical Chemistry Urea (Blood Urea Nitrogen - BUN) UC Davis IMPC 5.53E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_CBC_004_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_004_001&phenotyping_center=UC Davis decreased circulating cholesterol level Ppp2r5c homozygote female Early adult Clinical Chemistry Total cholesterol UC Davis IMPC 5.76E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_CBC_015_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_015_001&phenotyping_center=UC Davis increased circulating alkaline phosphatase level Ppp2r5c homozygote female Early adult Clinical Chemistry Alkaline phosphatase UC Davis IMPC 5.89E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=UC Davis increased monocyte cell number Ppp2r5c homozygote female Early adult Hematology Monocyte cell count UC Davis IMPC 7.53E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_HEM_034_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_HEM_002¶meter_stable_id=IMPC_HEM_034_001&phenotyping_center=UC Davis shortened QT interval Ppp2r5c homozygote male Early adult Electrocardiogram (ECG) QT UC Davis IMPC 9.87E-5 //dev.mousephenotype.org/data/charts?accession=MGI:1349475&allele_accession_id=MGI:6277066&zygosity=homozygote¶meter_stable_id=IMPC_ECG_028_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ECG_003¶meter_stable_id=IMPC_ECG_028_001&phenotyping_center=UC Davis