The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Trim14 by phenotypic similarity.
|Infection-Related Hemolytic Uremic Syndrome||
||Increased circulating interleukin 6 concentration, Meningitis, Severe infection, Abnormality of i...||ORPHA:544482|
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
|MGI Allele||Allele Type||Produced|
|Trim14em1(IMPC)Mbp||Inter-exon deletion||Mice, Tissue|
|Trim14tm1a(KOMP)Wtsi||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors, ES Cells|