Gene: Slc6a5

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Name
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
MGI ID
MGI:105090
Synonyms
Glyt2
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Slc6a5tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal eye morphology Slc6a5tm1.1(KOMP)Vlcg HET E12.5 0.00
increased mean corpuscular hemoglobin concentration Slc6a5tm1.1(KOMP)Vlcg HET Early adult 3.62×10-06
abnormal hindbrain development Slc6a5tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal midbrain development Slc6a5tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal embryo size Slc6a5tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal forebrain development Slc6a5tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal neural tube closure Slc6a5tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal pericardium morphology Slc6a5tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal craniofacial morphology Slc6a5tm1.1(KOMP)Vlcg HET E12.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (3/590)  (2/3)  Section images
Aorta 3 No  (1/590) N/A
Blood 3 No N/A
Bone marrow 3 No N/A
Brain 3 No  (3/590)  (1/3)  Wholemount images
Brainstem 3 No  (2/590) N/A
Brown adipose tissue 3 No N/A
Cartilage tissue 3 No N/A
Cecum 3 No  (12/377)  (1/3) N/A
Cerebellum 3 No  (3/590)  (2/3)  Wholemount images  Section images
Cerebral cortex 3 No  (2/590) N/A
Chest bone 3 No N/A
Colon 3 No  (12/127)  (1/3) N/A
Diaphragm 3 No N/A
Duodenum 3 No  (2/127) N/A
Epididymis 3 No  (18/134)  (2/3)  Section images
Esophagus 3 No  (7/415)  (1/3)  Section images
Eye 3 No N/A
Gall bladder 3 No N/A
Gonadal fat pad 3 No N/A
Harderian gland 3 No N/A
Heart 3 No  (1/590) N/A
Hindlimb 3 No N/A
Hippocampus 3 No  (3/590) N/A
Hypothalamus 3 No  (2/590) N/A
Ileum 3 No  (14/127)  (1/3) N/A
Jejunum 3 No  (6/127) N/A
Kidney 3 No  (20/590)  (1/3)  Wholemount images
Large intestine 3 No  (10/590) N/A
Liver 3 No N/A
Lower urinary tract 3 No  (1/590) N/A
Lung 3 No  (1/590) N/A
Lymph node 3 No N/A
Mammary gland 3 No N/A
Mesenteric adipose tissue 3 No N/A
Mesenteric lymph node 3 No N/A
Midbrain 3 No  (3/3)  Wholemount images  Section images
Olfactory lobe 3 No  (2/590) N/A
Ovary 3 No  (1/590) N/A
Oviduct 3 No N/A
Pancreas 3 No  (5/590) N/A
Parathyroid gland 3 No N/A
Parotid gland 3 No N/A
Penis 3 No N/A
Peripheral nervous system 3 No  (1/590) N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No  (1/590) N/A
Prostate gland 3 No  (12/590)  (1/3)  Section images
Quadriceps 3 No N/A
Sciatic nerve 3 No N/A
Skeletal muscle 3 No N/A
Skin 3 No N/A
Small intestine 3 No  (9/590) N/A
Spinal cord 3 No  (2/590)  (3/3)  Wholemount images  Section images
Spleen 3 No  (2/590) N/A
Stomach 3 No  (13/590)  (1/3) N/A
Stomach pyloric region 3 No N/A
Striatum 3 No  (3/590) N/A
Sublingual gland 3 No N/A
Submandibular gland 3 No  (2/132) N/A
Testis 3 No  (5/590) N/A
Thymus 3 No N/A
Thyroid gland 3 No  (16/590)  (1/3) N/A
Tongue 3 No  (5/127) N/A
Trachea 3 No  (2/590) N/A
Trigeminal V nerve 3 No N/A
Urinary bladder 3 No N/A
Uterus 3 No N/A
Vagina 3 No N/A
Vas deferens 3 No  (15/388)  (2/3)  Section images
Vascular system 3 No N/A
Vesicular gland 3 No N/A
White adipose tissue 3 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65) N/A
Brain 4  (6/506)  (2/10) N/A
Central nervous system ganglion 2  (1/74) N/A
Ear 4  (1/506) N/A
Embryo 4  (1/507)  (2/10) N/A
Eye 4  (1/506) N/A
Foot 4  (1/506) N/A
Forebrain 4  (1/506) N/A
Forelimb 4  (1/506) N/A
Gut 2  (1/60) N/A
Hand 4  (1/506) N/A
Head 4  (5/506) N/A
Heart 4  (1/506) N/A
Hindbrain 4  (6/506)  (2/10) N/A
Hindlimb 4  (1/506) N/A
Liver 4  (1/504) N/A
Lung 4  (1/504) N/A
Mandibular process 4  (1/506) N/A
Maxillary process 4  (1/506) N/A
Midbrain 4  (1/506) N/A
Nose 2  (1/76) N/A
Oral cavity 4  (1/504) N/A
Skeleton 2  (1/76) N/A
Skin 4  (1/506) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Tail 4  (1/506) N/A
Tail somite 4  (1/506) N/A
Trachea 2  (1/60) N/A
Urinary system 2  (1/60) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
44 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images
X-ray: XRay Images Whole Body Dorso Ventral
20 Images
Gross Morphology Embryo E9.5
2 Images
Adult LacZ: LacZ Images Section
21 Images
Adult LacZ: LacZ Images Wholemount
6 Images

 Disease Models

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MGI Allele Allele Type Produced
Slc6a5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Slc6a5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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