Phenotype: increased T-helper cell number

Definition
increase in the number of an effector T cell that provides help in the form of secreted cytokines to other immune cells
Synonyms
increased helper T lymphocyte number,  increased helper T cell number,  increased helper T-lymphocyte number,  increased helper T-cell number
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased T-helper cell number

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM   Early adult increased T-helper cell number CD4+ T helper cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Card11
Card11em1(IMPC)Ccpcz
HOM Early adult increased T-helper cell number CD4+ T helper cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
1.86×10-12
Clock
Clockem1(IMPC)Ccpcz
HOM Early adult increased T-helper cell number CD4+ T helper cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
1.37×10-08
Psmb11
Psmb11em1(IMPC)Ccpcz
HOM Early adult increased T-helper cell number CD4+ T helper cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
3.58×10-06
Pstpip1
Pstpip1em1(IMPC)Ccpcz
HOM Early adult increased T-helper cell number CD4+ T helper cells - % of live leukocytes (Panel A)
Immunophenotyping
CCP-IMG
IMPC
1.90×10-05

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 The way we measure

 Phenotype associations stats

0.66% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased T-helper cell number (5/752)

1.03% females (3/290) 0.69% males (2/289)

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