Definition
increase in the number of the naìˆve regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions with a CD44-low CD62L+ phenotype
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased CD8-positive, naive alpha-beta T cell number
Total number of significant genotype-phenotype associations: 10
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| D6Wsu163e D6Wsu163etm1b(EUCOMM)Wtsi |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem127 Tmem127tm1(KOMP)Wtsi |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Naive CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Spata31f3 Spata31f3em1(IMPC)Ccpcz |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
9.85×10-15 | |
| Card11 Card11em1(IMPC)Ccpcz |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.67×10-13 | |
| Rasgrp3 Rasgrp3em1(IMPC)Wtsi |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.11×10-06 | |
| Fam221a Fam221aem1(IMPC)Ccpcz |
HOM | Early adult | increased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
6.59×10-06 | |
| Fbxw16 Fbxw16em1(IMPC)Ccpcz |
HET | Early adult | increased CD8-positive, naive alpha-beta T cell number | Resting CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.04×10-05 |