Phenotype: shortened PQ interval

Definition
decrease in the length of time between the beginning of atrial depolarization and the end of atrial repolarization (or recovery), measured by the interval from the beginning of the P wave to the end of the Q wave
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened PQ interval

Total number of significant genotype-phenotype associations: 13

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.77×10-07
Ermp1
Ermp1tm1.1(KOMP)Vlcg
HOM Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
JAX
IMPC
1.11×10-05
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
JAX
IMPC
2.72×10-05
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
HMGU
IMPC
3.03×10-05
Iqca1
Iqca1em1(IMPC)J
HOM Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
JAX
IMPC
3.06×10-05
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM   Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
JAX
IMPC
3.12×10-05
Esrra
Esrratm1.1(KOMP)Vlcg
HOM Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
JAX
IMPC
3.89×10-05
Gsta4
Gsta4tm1b(EUCOMM)Hmgu
HOM   Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
HMGU
IMPC
4.44×10-05
Sycp3
Sycp3tm1.1(KOMP)Vlcg
HOM   Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
JAX
IMPC
4.84×10-05
Enox1
Enox1tm1.1(KOMP)Vlcg
HET Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
JAX
IMPC
5.04×10-05
Ano6
Ano6em3(IMPC)Tcp
HET Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
TCP
IMPC
6.17×10-05
Cyp4b1
Cyp4b1tm1b(KOMP)Wtsi
HOM Early adult shortened PQ interval PQ
Electrocardiogram (ECG)
HMGU
IMPC
7.71×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.45% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened PQ interval (12/2678)

0.11% females (3/2655) 0.26% males (7/2650)



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