Phenotype: shortened PR interval

Definition
decrease in the length of time between the beginning of atrial depolarization and the beginning of ventricular depolarization, measured by the interval from the beginning of the P wave to the beginning of the QRS complex
Synonyms
decreased PR interval,  reduced PR interval
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened PR interval

Total number of significant genotype-phenotype associations: 15

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
MRC Harwell
IMPC
5.28×10-08
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
1.81×10-06
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
1.97×10-06
Iqca1
Iqca1em1(IMPC)J
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
5.91×10-06
Gnl1
Gnl1em1(IMPC)Tcp
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
TCP
IMPC
8.85×10-06
Limd1
Limd1em1(IMPC)H
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.37×10-05
Gpr150
Gpr150em1(IMPC)J
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
4.38×10-05
Tmem256
Tmem256tm1.1(KOMP)Vlcg
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
UC Davis
IMPC
4.53×10-05
Cyp4b1
Cyp4b1tm1b(KOMP)Wtsi
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
4.53×10-05
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
4.99×10-05
Dnaaf1
Dnaaf1em1(IMPC)J
HET Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
7.30×10-05
Mrgprd
Mrgprdtm1b(EUCOMM)Hmgu
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
7.53×10-05
Lbr
Lbrem1(IMPC)Tcp
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
TCP
IMPC
8.89×10-05
Ociad1
Ociad1em1(IMPC)J
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
9.19×10-05
Zdhhc5
Zdhhc5tm1e.1(EUCOMM)Hmgu
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
9.82×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.25% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened PR interval (15/6012)

0.12% females (7/5972) 0.08% males (5/5963)



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