Phenotype: shortened QRS complex duration

Definition
decrease in the length of time of the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarize prior to their contraction; prolongation of the QRS complex duration reflects slowed conduction in the heart
Synonyms
shortened QRS duration,  shortened QRS interval,  narrow QRS complex
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened QRS complex duration

Total number of significant genotype-phenotype associations: 22

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Acad11
Acad11em1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
1.88×10-09
Ttc29
Ttc29em1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
2.21×10-07
Ggnbp2
Ggnbp2tm1b(KOMP)Wtsi
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
2.62×10-07
Mgrn1
Mgrn1em1(IMPC)Tcp
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
1.06×10-06
Nxnl2
Nxnl2em1(IMPC)Ccpcz
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
CCP-IMG
IMPC
6.72×10-06
Zc3h7b
Zc3h7bem1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
7.53×10-06
Nhs
Nhsem1(IMPC)Tcp
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
9.83×10-06
Fastkd5
Fastkd5em1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
1.34×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
UC Davis
IMPC
1.71×10-05
Thoc6
Thoc6em5(IMPC)Tcp
HET   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
2.19×10-05
Rbl1
Rbl1tm1b(EUCOMM)Hmgu
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
HMGU
IMPC
2.31×10-05
Prdm12
Prdm12tm2b(EUCOMM)Hmgu
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
2.56×10-05
Rcan3
Rcan3em1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
3.64×10-05
Atp1b1
Atp1b1em1(IMPC)Mbp
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
UC Davis
IMPC
4.14×10-05
Plscr1
Plscr1tm1b(EUCOMM)Hmgu
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
ICS
IMPC
4.37×10-05
Snx12
Snx12em1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
5.35×10-05
Ptp4a2
Ptp4a2em1(IMPC)Tcp
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
6.08×10-05
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
UC Davis
IMPC
6.47×10-05
Tagln2
Tagln2em1(IMPC)Tcp
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
6.48×10-05
Pipox
Pipoxtm1b(EUCOMM)Wtsi
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
8.14×10-05
Ecrg4
Ecrg4tm1b(EUCOMM)Hmgu
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
ICS
IMPC
8.75×10-05

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 The way we measure

 Phenotype associations stats

0.35% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened QRS complex duration (21/6012)

0.22% females (13/5979) 0.07% males (4/5972)



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