Phenotype: abnormal retinal blood vessel morphology

Phenotype associations stats

0.89% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal retinal blood vessel morphology (33/3724)

0.40% females (15/3706) 0.70% males (26/3699)

Gene variants with abnormal retinal blood vessel morphology

Total number of significant genotype-phenotype associations: 42

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Ube2a
Ube2atm1.1(KOMP)Vlcg
HEM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 0.0
Mpdz
Mpdzem1(IMPC)J
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 2.22E-18
Col18a1
Col18a1tm1.1(KOMP)Vlcg
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 5.45E-15
Mapt
Mapttm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 1.13E-13
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 1.0E-11
Prkab1
Prkab1tm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 6.59E-11
Timp3
Timp3tm1.1(KOMP)Vlcg
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 2.55E-9
Lss
Lsstm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.99E-8
Ncald
Ncaldtm1.1(KOMP)Vlcg
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 8.42E-8
Trmt1
Trmt1tm1b(EUCOMM)Hmgu
HET Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 2.23E-7
Hdac1
Hdac1tm1b(EUCOMM)Wtsi
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.35E-6
Wsb2
Wsb2tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.42E-6
Hnf4a
Hnf4atm1b(EUCOMM)Hmgu
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.03E-6
Etfdh
Etfdhtm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.64E-6
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern MRC Harwell | IMPC 9.43E-6
Prdm5
Prdm5em1(IMPC)Tcp
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern TCP | IMPC 1.17E-5
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.23E-5
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.5E-5
Emc8
Emc8tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 1.88E-5
Rcn1
Rcn1tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.61E-5
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.7E-5
Wdsub1
Wdsub1tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.74E-5
Pcsk1
Pcsk1tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 3.41E-5
Zbtb24
Zbtb24tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.53E-5
Asb2
Asb2tm2b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 3.63E-5
Rnf38
Rnf38tm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.81E-5
Cr1l
Cr1ltm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.91E-5
Nos1ap
Nos1aptm1b(KOMP)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 5.27E-5
Tmem151b
Tmem151btm1b(KOMP)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 6.31E-5
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.74E-5
Spryd3
Spryd3tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.36E-5
Pdhx
Pdhxtm1b(EUCOMM)Hmgu
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.44E-5
Nbas
Nbastm1b(EUCOMM)Hmgu
HET Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.68E-5
Foxk2
Foxk2em1(IMPC)J
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 9.95E-5

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Images

  • Polr1etm1a(KOMP)Wtsi
    EYE, abnormal retinal blood vessel structure, abnormal optic disc morphology, HET, Female, WTSI
  • Polr1etm1a(KOMP)Wtsi
    EYE, abnormal optic disc morphology, abnormal retinal blood vessel structure, HET, Female, WTSI
  • Kptntm1a(EUCOMM)Wtsi
    EYE, abnormal retinal blood vessel structure, HOM, Female, WTSI
  • Stard6tm1a(KOMP)Wtsi
    EYE, abnormal retinal blood vessel morphology, HOM, Male, WTSI
  • Stard6tm1a(KOMP)Wtsi
    EYE, abnormal retinal blood vessel morphology, HOM, Male, WTSI

Associated Images

  • Eye Morphology: Images Ophthalmoscopy
    63 Images