Phenotype: abnormal retinal blood vessel morphology

Phenotype associations stats

1.06% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal retinal blood vessel morphology (38/3575)

0.42% females (15/3562) 0.87% males (31/3563)

Gene variants with abnormal retinal blood vessel morphology

Total number of significant genotype-phenotype associations: 46

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Gjc3
Gjc3em1(IMPC)Bay
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 0.0
Mpdz
Mpdzem1(IMPC)J
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 4.08E-18
Col18a1
Col18a1tm1.1(KOMP)Vlcg
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 6.5E-15
Mapt
Mapttm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 1.53E-13
Prkab1
Prkab1tm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 6.59E-11
Timp3
Timp3tm1.1(KOMP)Vlcg
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 3.63E-9
Lss
Lsstm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.99E-8
Lrrc51
Lrrc51tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.23E-8
Ncald
Ncaldtm1.1(KOMP)Vlcg
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 6.02E-8
Trmt1
Trmt1tm1b(EUCOMM)Hmgu
HET Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 1.95E-7
Tnpo2
Tnpo2tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.82E-7
Hdac1
Hdac1tm1b(EUCOMM)Wtsi
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.35E-6
S1pr3
S1pr3tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.43E-6
Brd4
Brd4tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 1.44E-6
Gpr25
Gpr25em1(IMPC)Bay
HOM Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.16E-6
Wsb2
Wsb2tm1b(EUCOMM)Hmgu
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.42E-6
Nxn
Nxnem1(IMPC)Bay
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.52E-6
Msmb
Msmbtm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 6.48E-6
Hnf4a
Hnf4atm1b(EUCOMM)Hmgu
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.03E-6
Ift172
Ift172tm2b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 8.5E-6
Etfdh
Etfdhtm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.64E-6
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern MRC Harwell | IMPC 1.04E-5
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.23E-5
Prdm5
Prdm5em1(IMPC)Tcp
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern TCP | IMPC 1.39E-5
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.5E-5
Emc8
Emc8tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 2.07E-5
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.7E-5
Asb2
Asb2tm2b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 2.92E-5
Rnf38
Rnf38tm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.15E-5
Zbtb24
Zbtb24tm1b(EUCOMM)Hmgu
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.53E-5
Nos1ap
Nos1aptm1b(KOMP)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 4.93E-5
Cr1l
Cr1ltm1b(KOMP)Wtsi
HET Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 5.87E-5
Foxk2
Foxk2em1(IMPC)J
HOM Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 6.55E-5
Tmem151b
Tmem151btm1b(KOMP)Wtsi
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 7.54E-5
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.74E-5
Spryd3
Spryd3tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.36E-5
Pdhx
Pdhxtm1b(EUCOMM)Hmgu
HET Female Male postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.44E-5
Nbas
Nbastm1b(EUCOMM)Hmgu
HET Female postnatal abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.68E-5

Download data as: TSV XLS

Images

  • Kptntm1a(EUCOMM)Wtsi
    EYE, abnormal retinal blood vessel structure, HOM, Female, WTSI
  • Polr1etm1a(KOMP)Wtsi
    EYE, abnormal retinal blood vessel structure, abnormal optic disc morphology, HET, Female, WTSI
  • Polr1etm1a(KOMP)Wtsi
    EYE, abnormal optic disc morphology, abnormal retinal blood vessel structure, HET, Female, WTSI
  • Daam2tm1a(KOMP)Wtsi
    abnormal retinal blood vessel morphology, HOM, Male, WTSI
  • Wbp5tm1a(KOMP)Wtsi
    RIGHT EYE, abnormal retinal blood vessel morphology, HOM, Female, WTSI

Associated Images

  • Eye Morphology: Images Ophthalmoscopy
    55 Images