IMPC Gene variants with decreased B-2 B cell number
Total number of significant genotype-phenotype associations: 6
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased B-2 B cell number | Total B2 cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Tmem127 Tmem127tm1(KOMP)Wtsi |
HOM | Early adult | decreased B-2 B cell number | Total B2 cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased B-2 B cell number | B2B Cells Immunophenotyping |
HMGU IMPC |
2.22×10-11 | |
Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased B-2 B cell number | B2B Cells Immunophenotyping |
CCP-IMG IMPC |
9.67×10-11 | |
Pepd Pepdtm1b(KOMP)Wtsi |
HOM | Late adult | decreased B-2 B cell number | B2B Cells Immunophenotyping |
HMGU IMPC |
1.91×10-05 |