Definition
reduced number of resting mature B cells with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen and lymph nodes
Synonyms
reduced follicular B cell number
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased follicular B cell number
Total number of significant genotype-phenotype associations: 7
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of B2 cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Arhgap17 Arhgap17tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B Cells (CD21/35+) Immunophenotyping |
HMGU IMPC |
1.68×10-10 | |
| Pepd Pepdtm1b(KOMP)Wtsi |
HOM | Late adult | decreased follicular B cell number | Follicular B Cells Immunophenotyping |
HMGU IMPC |
1.07×10-05 |