Phenotype: thick ventricular wall

Definition increased depth of the cardiac wall of the heart ventricles

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Phenotype associations stats

0.74% of tested genes with null mutations on a B6N genetic background have a phenotype association to thick ventricular wall (9/1212)

0.58% females (7/1198) 0.65% males (6/929)

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Gene variants with thick ventricular wall

Total number of significant genotype-phenotype associations: 13

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM Female postnatal thick ventricular wall Echo | LVPWd MRC Harwell | IMPC 3.5E-15
Wfdc11
Wfdc11em1(IMPC)Marc
HOM Female Male postnatal thick ventricular wall Echo | LVPWd MARC | IMPC 1.28E-12
Erg
Ergem1(IMPC)Bay
HET Female Male postnatal thick ventricular wall Echo | LVPWs BCM | IMPC 1.27E-6
Yipf5
Yipf5tm1b(EUCOMM)Hmgu
HET Male postnatal thick ventricular wall Echo | LVPWd ICS | IMPC 5.74E-6
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
HOM Female postnatal thick ventricular wall Echo | LVPWd MARC | IMPC 1.08E-5
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET Female Male postnatal thick ventricular wall Echo | LVPWd HMGU | IMPC 1.74E-5
Mpzl2
Mpzl2tm1b(EUCOMM)Hmgu
HET Male postnatal thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 2.73E-5
Pdx1
Pdx1tm1b(EUCOMM)Wtsi
HET Female Male postnatal thick ventricular wall Echo | LVPWs BCM | IMPC 4.64E-5
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu
HOM Female postnatal thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 7.93E-5

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