Phenotype: decreased heart weight

Definition less than average weight of the heart compared to controls

Synonyms reduced heart weight
Related
Synonyms
  • decreased heart right atrium weight
  • decreased heart right atrium weight
  • decreased heart left atrium weight
  • decreased heart left atrium weight
  • decreased heart right ventricle weight
  • decreased heart left ventricle weight
Show more

MP browserMP:0002834

Phenotype associations stats

0.95% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart weight (38/3984)

0.69% females (27/3918) 0.86% males (34/3942)

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Gene variants with decreased heart weight

Total number of significant genotype-phenotype associations: 61

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.88E-39
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight WTSI | IMPC 5.62E-11
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.93E-9
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight MARC | IMPC 2.17E-8
Trh
Trhem1(IMPC)Tcp
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight TCP | IMPC 1.07E-7
Kiss1r
Kiss1rtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.15E-7
Mtmr12
Mtmr12tm1b(KOMP)Wtsi
HOM Male postnatal decreased heart weight Heart Weight | Heart weight ICS | IMPC 9.73E-7
Tlr4
Tlr4tm1.1(KOMP)Vlcg
HOM Male postnatal decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.8E-6
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Male postnatal decreased heart weight Heart Weight | Heart weight ICS | IMPC 2.24E-6
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight MARC | IMPC 2.45E-6
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased heart weight Heart Weight | Heart weight ICS | IMPC 8.56E-6
Snip1
Snip1tm1a(EUCOMM)Wtsi
HET Female postnatal decreased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 9.07E-6
Acsl4
Acsl4tm1a(EUCOMM)Wtsi
HET Female postnatal decreased heart weight Heart Dissection | Heart weight WTSI | MGP 1.13E-5
Dync1h1
Dync1h1tm1dIcs
HET Male postnatal decreased heart weight Heart Weight | Heart weight ICS | IMPC 1.21E-5
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight RBRC | IMPC 1.22E-5
Grin2d
Grin2dtm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 1.25E-5
Mmp9
Mmp9tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight ICS | IMPC 1.42E-5
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.71E-5
Ly6g6d
Ly6g6dtm1b(EUCOMM)Hmgu
HOM Male postnatal decreased heart weight Heart Weight | Heart weight HMGU | IMPC 1.82E-5
Gpr61
Gpr61em1(IMPC)Bay
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight BCM | IMPC 2.57E-5
Coq2
Coq2tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.64E-5
Nr1h3
Nr1h3tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 2.87E-5
Fndc9
Fndc9tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.03E-5
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight WTSI | IMPC 3.04E-5
Sparc
Sparctm1a(EUCOMM)Wtsi
HOM Male postnatal decreased heart weight Heart weight/tibia length | Heart weight WTSI | EuroPhenome 3.3E-5
Pink1
Pink1tm1b(EUCOMM)Wtsi
HOM Female postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 3.46E-5
Mbtd1
Mbtd1tm2a(EUCOMM)Wtsi
HET Female Male postnatal decreased heart weight Heart Dissection | Heart weight WTSI | MGP 4.76E-5
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.94E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Female postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 5.08E-5
P2rx4
P2rx4tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 6.3E-5
Ccdc57
Ccdc57tm1a(EUCOMM)Wtsi
HET Male postnatal decreased heart weight Heart Dissection | Heart weight WTSI | MGP 7.08E-5
Prf1
Prf1tm1.1(KOMP)Vlcg
HOM Male postnatal decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 7.75E-5
Fbxo38
Fbxo38em2(IMPC)Marc
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight MARC | IMPC 8.29E-5
Kctd13
Kctd13em2(IMPC)Ics
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight ICS | IMPC 8.36E-5
Hnrnpr
Hnrnprem1(IMPC)Marc
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight MARC | IMPC 8.39E-5
Vwa1
Vwa1tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.71E-5
Il31ra
Il31ratm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 9.31E-5
Clstn2
Clstn2em1(IMPC)J
HOM Male postnatal decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.83E-5

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