Definition
reduced concentration of naturally occurring esters of three fatty acids and glycerol in the blood; triglycerides are widespread in adipose tissue, commonly circulate in the blood in the form of lipoproteins, and are involved in the process of bidirectional transference of adipose fat and blood glucose with the liver
Synonyms
reduced circulating triglyceride level
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased circulating triglyceride level
Total number of significant genotype-phenotype associations: 114
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Dll1 Dll1tm1Gos |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical chemistry (GMC) |
HMGU EuroPhenome |
3.58×10-27 | |
| Atp8b1 Atp8b1em1(IMPC)Tcp |
HOM | Late adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
9.00×10-22 | |
| Akt2 Akt2tm1Wcs |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
WTSI MGP |
1.05×10-21 | |
| Rnf10 Rnf10tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
1.48×10-15 | |
| Angptl3 Angptl3tm2b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
4.09×10-15 | |
| Bbs5 Bbs5tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
1.74×10-14 | |
| Fbxo10 Fbxo10tm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MARC IMPC |
6.87×10-13 | |
| Arhgef4 Arhgef4tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
5.39×10-12 | |
| Ppp5c Ppp5ctm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
WTSI EuroPhenome |
1.15×10-11 | |
| Gna11 Gna11tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
3.34×10-10 | |
| Dym Dymem1(IMPC)Tcp |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
4.52×10-10 | |
| Cpgi5563 Cpgi5563tm1.1(NCC)WCS |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
7.46×10-10 | |
| Abcd3 Abcd3em1(IMPC)J |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
1.00×10-09 | |
| Cisd2 Cisd2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
1.41×10-09 | |
| Crispld2 Crispld2tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
6.00×10-09 | |
| Hells Hellstm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
6.13×10-09 | |
| Cyp4b1 Cyp4b1tm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
9.51×10-09 | |
| Slc38a10 Slc38a10tm2a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
1.77×10-08 | |
| Mysm1 Mysm1tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
HMGU EuroPhenome |
1.88×10-08 | |
| Pde6b Pde6bPde6b |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical chemistry (GMC) |
HMGU EuroPhenome |
2.50×10-08 | |
| Tmem167 Tmem167tm1a(EUCOMM)Hmgu |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
2.51×10-08 | |
| Taco1 Taco1em1(IMPC)J |
HOM | Late adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
6.44×10-08 | |
| Grin2d Grin2dtm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
7.32×10-08 | |
| Mysm1 Mysm1tm1a(KOMP)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
9.68×10-08 | |
| Cd36 Cd36em1(IMPC)Mbp |
HOM | Late adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
1.05×10-07 | |
| Fam234b Fam234btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
1.55×10-07 | |
| Col11a2 Col11a2tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
2.37×10-07 | |
| Cdkn1b Cdkn1bem2(IMPC)H |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
2.87×10-07 | |
| Arr3 Arr3em1(IMPC)J |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
3.99×10-07 | |
| Cisd1 Cisd1em1(IMPC)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
6.09×10-07 | |
| Dennd5b Dennd5bem1(IMPC)Tcp |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
7.12×10-07 | |
| Cnot3 Cnot3em1(IMPC)Rbrc |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
RBRC IMPC |
7.17×10-07 | |
| Hmx3 Hmx3tm1Ebo |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
WTSI MGP |
7.31×10-07 | |
| Grin3b Grin3btm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
7.47×10-07 | |
| Myo6 Myo6Tlc |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical chemistry (GMC) |
HMGU EuroPhenome |
8.59×10-07 | |
| Dll1 Dll1m1Mhda |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
HMGU EuroPhenome |
1.02×10-06 | |
| Ctsa Ctsatm2b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
1.74×10-06 | |
| Ndufs1 Ndufs1tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
1.77×10-06 | |
| Elk4 Elk4tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
1.85×10-06 | |
| Hbp1 Hbp1not yet available |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
2.35×10-06 | |
| Diaph3 Diaph3tm1b(KOMP)Mbp |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
3.19×10-06 | |
| Acsl5 Acsl5tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
3.19×10-06 | |
| Gc Gctm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
4.44×10-06 | |
| Btbd16 Btbd16tm2b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
BCM IMPC |
4.93×10-06 | |
| Ephx1 Ephx1Ephx1 |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
ICS EuroPhenome |
6.65×10-06 | |
| Cyp27a1 Cyp27a1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
7.23×10-06 | |
| Grhl3 Grhl3tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
ICS EuroPhenome |
7.71×10-06 | |
| Fam117b Fam117btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
8.12×10-06 | |
| Gpr146 Gpr146em1(IMPC)H |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
9.71×10-06 | |
| Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
ICS IMPC |
9.88×10-06 | |
| Rnf7 Rnf7tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
1.04×10-05 | |
| Mmp11 Mmp11tm1a(EUCOMM)Hmgu |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
1.09×10-05 | |
| Pax7 Pax7tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Plasma Chemistry |
JAX IMPC |
1.12×10-05 | |
| Pitx3 Pitx3eyl |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical chemistry (GMC) |
HMGU EuroPhenome |
1.13×10-05 | |
| Acbd3 Acbd3tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
1.20×10-05 | |
| Tagap1 Tagap1em1(IMPC)Tcp |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
1.35×10-05 | |
| Nfkbid Nfkbidtm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
1.52×10-05 | |
| Csnk2a2 Csnk2a2em1(IMPC)Mbp |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
1.66×10-05 | |
| Fam83g Fam83gtm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
1.68×10-05 | |
| Osbpl11 Osbpl11tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
1.70×10-05 | |
| Slc29a3 Slc29a3em1(IMPC)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
1.72×10-05 | |
| Cc2d1b Cc2d1btm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
WTSI EuroPhenome |
1.83×10-05 | |
| Ska2 Ska2tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
1.86×10-05 | |
| Tnks Tnksem1(IMPC)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
1.96×10-05 | |
| Il17rc Il17rcem1(IMPC)Mbp |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
1.99×10-05 | |
| Tial1 Tial1tm1b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
2.15×10-05 | |
| Nepn Nepntm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
2.26×10-05 | |
| Ubash3a Ubash3atm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
2.53×10-05 | |
| Cenpo Cenpotm1b(KOMP)Mbp |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Plasma Chemistry |
JAX IMPC |
2.73×10-05 | |
| Pck2 Pck2em1(IMPC)Tcp |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
2.81×10-05 | |
| C2cd4b C2cd4bem1(IMPC)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
2.90×10-05 | |
| Txndc5 Txndc5tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
2.93×10-05 | |
| Abcb11 Abcb11tm1b(EUCOMM)Hmgu |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
3.05×10-05 | |
| Ttc39b Ttc39btm1e(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
WTSI EuroPhenome |
3.21×10-05 | |
| Cybc1 Cybc1tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
WTSI MGP |
3.27×10-05 | |
| Drg2 Drg2tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
ICS EuroPhenome |
3.29×10-05 | |
| Wac Wactm2b(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
3.46×10-05 | |
| Phex Phexnot yet available |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
HMGU EuroPhenome |
3.55×10-05 | |
| Npcd Npcdem1(IMPC)J |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
3.60×10-05 | |
| Pik3c3 Pik3c3tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
ICS EuroPhenome |
3.90×10-05 | |
| Cpgi15344 Cpgi15344tm1.1(NCC)WCS |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
4.70×10-05 | |
| Fads1 Fads1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
4.81×10-05 | |
| Xbp1 Xbp1tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
HMGU EuroPhenome |
4.85×10-05 | |
| D630045J12Rik D630045J12Riktm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
5.50×10-05 | |
| Cap2 Cap2tm1e(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
5.51×10-05 | |
| Ngfr Ngfrtm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
ICS EuroPhenome |
5.91×10-05 | |
| Pknox1 Pknox1Gt(EUCJ0079d10)Hmgu |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
5.94×10-05 | |
| Plcg2 Plcg2Ali14 |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
HMGU EuroPhenome |
5.97×10-05 | |
| Slain2 Slain2em1(IMPC)J |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
6.08×10-05 | |
| Dbnl Dbnltm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
ICS IMPC |
6.10×10-05 | |
| Ucp1 Ucp1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
HMGU IMPC |
6.13×10-05 | |
| Snx12 Snx12em1(IMPC)J |
HEM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
6.45×10-05 | |
| C1qtnf1 C1qtnf1em1(IMPC)Mbp |
HOM | Late adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
UC Davis IMPC |
7.02×10-05 | |
| Fbxo11 Fbxo11Jf |
HET | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
MRC Harwell EuroPhenome |
7.24×10-05 | |
| Mfsd1 Mfsd1em1(IMPC)Tcp |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
7.47×10-05 | |
| Angptl4 Angptl4tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
8.08×10-05 | |
| Acbd5 Acbd5tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
8.26×10-05 | |
| Tbc1d22a Tbc1d22atm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
8.32×10-05 | |
| Pde2a Pde2aem1(IMPC)H |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
8.63×10-05 | |
| Tnip1 Tnip1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
MRC Harwell IMPC |
8.73×10-05 | |
| Ap4e1 Ap4e1em1(IMPC)J |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
8.76×10-05 | |
| Atp13a3 Atp13a3em1(IMPC)J |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
JAX IMPC |
9.05×10-05 | |
| Psph Psphtm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
TCP IMPC |
9.07×10-05 | |
| Dlec1 Dlec1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating triglyceride level | Triglycerides Fasted Clinical Chemistry |
HMGU EuroPhenome |
9.07×10-05 | |
| Setd1b Setd1btm1.2(IMPC)Wtsi |
HET | Early adult | decreased circulating triglyceride level | Triglycerides Clinical Chemistry |
WTSI IMPC |
9.10×10-05 | |
| Rnase10 Rnase10tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating triglyceride level | Triglyceride Clinical Chemistry |
ICS EuroPhenome |
9.65×10-05 |