Phenotype: increased heart rate

Definition greater than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute

Synonyms tachycardia
Related
Synonyms
  • Supraventricular tachycardia
  • Supraventricular tachycardia
  • Ventricular flutter
  • Ventricular flutter
  • Polymorphic ventricular tachycardia
  • Paroxysmal supraventricular tachycardia
  • Supraventricular tachycardia with a manifest accessory pathway
  • Episodes of ventricular tachycardia
  • Effort-induced polymorphic ventricular tachycardias
  • Paroxysmal ventricular tachycardia
  • Monomorphic ventricular tachycardia
  • Paroxysmal tachycardia
  • Episodes of ventricular tachycardia
  • Supraventricular tachycardia with an accessory connection mediated pathway
  • Paroxysmal atrial tachycardia
  • Effort-induced polymorphic ventricular tachycardias
  • Fascicular left ventricular tachycardia
  • Polymorphic ventricular tachycardia
  • Supraventricular tachycardia with a concealed accessory connection
  • Atrioventricular reentrant tachycardia
  • Paroxysmal ventricular tachycardia
  • Ventricular flutter
  • Junctional ectopic tachycardia
  • ventricular tachycardia
  • Monomorphic ventricular tachycardia
  • AV nodal tachycardia
  • Fascicular left ventricular tachycardia
  • Ventricular tachycardia
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MP browserMP:0002626

Phenotype associations stats

0.98% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart rate (32/3278)

0.86% females (28/3258) 0.91% males (28/3073)

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Gene variants with increased heart rate

Total number of significant genotype-phenotype associations: 75

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Gnb2
Gnb2em1(IMPC)J
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 4.18E-9
Rrad
Rradtm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 6.88E-9
Rrad
Rradtm1.1(KOMP)Vlcg
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.29E-8
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HOM Male postnatal increased heart rate Echo | HR ICS | IMPC 1.83E-8
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.1E-8
Gnb2
Gnb2em1(IMPC)J
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.28E-8
Adprm
Adprmtm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart rate Echo | HR HMGU | IMPC 1.46E-7
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.68E-7
Mbd5
Mbd5tm1b(EUCOMM)Wtsi
HET Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR ICS | IMPC 8.92E-7
Hunk
Hunktm1b(EUCOMM)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 3.4E-6
Far2
Far2tm2b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.16E-6
Fsd2
Fsd2em1(IMPC)Mbp
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 6.77E-6
Hunk
Hunktm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR HMGU | IMPC 6.84E-6
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu
HOM Female postnatal increased heart rate Echo | HR MRC Harwell | IMPC 9.91E-6
Bzw2
Bzw2tm1b(KOMP)Mbp
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.16E-5
Far2
Far2tm2b(KOMP)Wtsi
HOM Female postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.37E-5
Trip13
Trip13tm1.1(KOMP)Vlcg
HET Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.05E-5
Phf19
Phf19tm1.1(KOMP)Vlcg
HOM Female postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.26E-5
Rec8
Rec8tm1b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.88E-5
Sun1
Sun1tm1b(EUCOMM)Wtsi
HOM Male postnatal increased heart rate Echo | HR ICS | IMPC 3.09E-5
Lin28b
Lin28btm1b(EUCOMM)Hmgu
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.27E-5
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 3.34E-5
Fsd2
Fsd2em1(IMPC)Mbp
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 3.38E-5
Hspb1
Hspb1tm1.1(KOMP)Vlcg
HOM Female postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.44E-5
Arr3
Arr3em1(IMPC)J
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.72E-5
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Female postnatal increased heart rate Echo | HR ICS | IMPC 4.22E-5
Ap3s1
Ap3s1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart rate Echo | HR HMGU | IMPC 4.41E-5
H1fx
H1fxtm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.42E-5
Phf19
Phf19tm1.1(KOMP)Vlcg
HOM Female postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 4.9E-5
Dock11
Dock11tm2b(KOMP)Wtsi
HEM Male postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 5.18E-5
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 5.2E-5
Vsig8
Vsig8tm1.1(KOMP)Mbp
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.6E-5
Pitx3
Pitx3tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 5.76E-5
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 6.81E-5
Rgs19
Rgs19em1(IMPC)J
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 6.85E-5
Trip13
Trip13tm1.1(KOMP)Vlcg
HET Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 6.9E-5
Nkg7
Nkg7tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 7.31E-5
Camk2b
Camk2btm1b(EUCOMM)Hmgu
HET Female Male postnatal increased heart rate Echo | HR HMGU | IMPC 7.57E-5
Arr3
Arr3em1(IMPC)J
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 8.11E-5
C9
C9tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 8.17E-5
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 8.33E-5
Hspb1
Hspb1tm1.1(KOMP)Vlcg
HOM Female postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 9.41E-5
Il18r1
Il18r1em1(IMPC)Mbp
HOM Male postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 9.77E-5

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