Phenotype: increased heart rate

Definition greater than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute

Synonyms tachycardia
Related
Synonyms
  • Polymorphic ventricular tachycardia
  • Polymorphic ventricular tachycardia
  • Supraventricular tachycardia
  • Supraventricular tachycardia
  • Paroxysmal ventricular tachycardia
  • Supraventricular tachycardia with an accessory connection mediated pathway
  • Paroxysmal ventricular tachycardia
  • Supraventricular tachycardia with a manifest accessory pathway
  • Supraventricular tachycardia with a concealed accessory connection
  • Monomorphic ventricular tachycardia
  • Ventricular flutter
  • Episodes of ventricular tachycardia
  • AV nodal tachycardia
  • Ventricular flutter
  • Junctional ectopic tachycardia
  • Fascicular left ventricular tachycardia
  • Episodes of ventricular tachycardia
  • Paroxysmal atrial tachycardia
  • Fascicular left ventricular tachycardia
  • ventricular tachycardia
  • Atrioventricular reentrant tachycardia
  • Polymorphic ventricular tachycardia
  • Monomorphic ventricular tachycardia
  • Paroxysmal tachycardia
  • Effort-induced polymorphic ventricular tachycardias
  • Ventricular tachycardia
  • Paroxysmal supraventricular tachycardia
  • Effort-induced polymorphic ventricular tachycardias
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MP browserMP:0002626

Phenotype associations stats

0.99% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart rate (33/3325)

0.82% females (27/3303) 0.90% males (28/3127)

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Gene variants with increased heart rate

Total number of significant genotype-phenotype associations: 72

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Rrad
Rradtm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 7.25E-9
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HOM Male postnatal increased heart rate Echo | HR ICS | IMPC 1.11E-8
Rrad
Rradtm1.1(KOMP)Vlcg
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.33E-8
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.39E-8
Adprm
Adprmtm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart rate Echo | HR HMGU | IMPC 1.46E-7
Snai3
Snai3tm2b(EUCOMM)Hmgu
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 1.79E-7
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.81E-7
Tmprss11b
Tmprss11btm1b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 4.46E-7
Mbd5
Mbd5tm1b(EUCOMM)Wtsi
HET Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR ICS | IMPC 8.19E-7
Far2
Far2tm2b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 8.37E-7
Tmprss11b
Tmprss11btm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR BCM | IMPC 2.08E-6
Bex2
Bex2tm1b(EUCOMM)Hmgu
HEM Male postnatal increased heart rate Echo | HR HMGU | IMPC 2.8E-6
Hunk
Hunktm1b(EUCOMM)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 3.4E-6
Far2
Far2tm2b(KOMP)Wtsi
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 3.45E-6
Arr3
Arr3em1(IMPC)J
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.48E-6
Hunk
Hunktm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR HMGU | IMPC 6.84E-6
Arr3
Arr3em1(IMPC)J
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 6.88E-6
Il18r1
Il18r1em1(IMPC)Mbp
HOM Male postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 9.12E-6
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu
HOM Female postnatal increased heart rate Echo | HR MRC Harwell | IMPC 9.91E-6
Bzw2
Bzw2tm1b(KOMP)Mbp
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.23E-5
Zfp395
Zfp395tm1b(EUCOMM)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 1.37E-5
Phf19
Phf19tm1.1(KOMP)Vlcg
HOM Female postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.28E-5
Trip13
Trip13tm1.1(KOMP)Vlcg
HET Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.44E-5
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 2.96E-5
Rec8
Rec8tm1b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.02E-5
Sun1
Sun1tm1b(EUCOMM)Wtsi
HOM Male postnatal increased heart rate Echo | HR ICS | IMPC 3.09E-5
Trim30b
Trim30btm1b(KOMP)Wtsi
HOM Female postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 3.5E-5
Lin28b
Lin28btm1b(EUCOMM)Hmgu
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.65E-5
Hspb1
Hspb1tm1.1(KOMP)Vlcg
HOM Female postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.9E-5
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Female postnatal increased heart rate Echo | HR ICS | IMPC 4.28E-5
Ap3s1
Ap3s1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart rate Echo | HR HMGU | IMPC 4.44E-5
C9
C9tm1.1(KOMP)Vlcg
HOM Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.75E-5
Phf19
Phf19tm1.1(KOMP)Vlcg
HOM Female postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 4.97E-5
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 5.14E-5
Dock11
Dock11tm2b(KOMP)Wtsi
HEM Male postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 5.26E-5
H1fx
H1fxtm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.35E-5
Pitx3
Pitx3tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 5.52E-5
Vsig8
Vsig8tm1.1(KOMP)Mbp
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 6.12E-5
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 7.08E-5
Nkg7
Nkg7tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 7.23E-5
Trip13
Trip13tm1.1(KOMP)Vlcg
HET Female Male postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 8.13E-5
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 9.38E-5

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