Significant MP calls for ICS Strains (ICS_001)
Total number of results: 1755
Gene / Allele | Procedure | Parameter | Zygosity | Sex | Phenotype | P-value | Graph |
---|---|---|---|---|---|---|---|
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Liver | heterozygote | abnormal liver morphology | 0.0 | ||
Cdon Cdontm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Nlk Nlktm2b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Rbfox1 Rbfox1tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Fertility of Homozygous Knock-out Mice | Gross Findings Female | homozygote | female infertility | 0.0 | ||
Pnpla1 Pnpla1tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Gross Morphology Embryo E9.5 | Severely Dysmorphic | homozygote | abnormal embryo development | 0.0 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Kidney | heterozygote | abnormal kidney morphology | 0.0 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | increased lean body mass | 0.0 | ||
Lmna Lmnatm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Kctd15 Kctd15tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Cbl Cbltm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Large intestine | homozygote | abnormal colon morphology | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Ect2 Ect2tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Atp6v1d Atp6v1dtm1b(EUCOMM)Hmgu |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
Satb1 Satb1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Coq6 Coq6tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Liver | homozygote | abnormal liver morphology | 0.0 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Testes | homozygote | small testis | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Small intestine | homozygote | abnormal duodenum morphology | 0.0 | ||
Gorasp1 Gorasp1tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Gross Pathology and Tissue Collection | Seminal vesicle | homozygote | abnormal seminal vesicle morphology | 0.0 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Prps1 Prps1tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Fertility of Homozygous Knock-out Mice | Gross Findings Female | homozygote | female infertility | 0.0 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Testes | homozygote | small testis | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Small intestine | homozygote | abnormal duodenum morphology | 0.0 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Fut4 Fut4em1(IMPC)Ics |
Gross Pathology and Tissue Collection | Kidney | homozygote | abnormal kidney morphology | 0.0 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Kidney | homozygote | polycystic kidney | 0.0 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Skin | homozygote | abnormal skin morphology | 0.0 | ||
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Heart | homozygote | abnormal heart morphology | 0.0 | ||
Ackr3 Ackr3tm2b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote | male infertility | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Albumin | homozygote | increased circulating serum albumin level | 0.0 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
Krt8 Krt8tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Testes | homozygote | small testis | 0.0 | ||
Phf6 Phf6tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Dbn1 Dbn1tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Pax4 Pax4tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Dnm1l Dnm1ltm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Ctsd Ctsdtm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Testes | homozygote | small testis | 0.0 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Fertility of Homozygous Knock-out Mice | Gross Findings Female | homozygote | female infertility | 0.0 | ||
Cflar Cflartm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Tnfrsf9 Tnfrsf9tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Gross Pathology and Tissue Collection | Eye with optic nerve | homozygote | anophthalmia | 0.0 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Skin | homozygote | abnormal skin morphology | 0.0 | ||
Septin3 Septin3tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Hematocrit | homozygote | decreased hematocrit | 0.0 | ||
Cdk8 Cdk8tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E9.5 | Neural tube closure | homozygote | abnormal neural tube closure | 0.0 | ||
Rwdd3 Rwdd3tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Spleen | homozygote | abnormal spleen morphology | 0.0 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Raf1 Raf1tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 0.0 | ||
Tgif2 Tgif2tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Uterus | homozygote | small superior vagus ganglion | 0.0 | ||
Atp6v1d Atp6v1dtm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Viability E9.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to organogenesis | 0.0 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 0.0 | ||
Scaper Scapertm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Kdm5c Kdm5ctm1d(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Large intestine | homozygote | abnormal colon morphology | 0.0 | ||
Lca5l Lca5lem1(IMPC)Ics |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote | male infertility | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 0.0 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Uterus | homozygote | small superior vagus ganglion | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | increased lean body mass | 0.0 | ||
Tti2 Tti2tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 0.0 | ||
Gatad2b Gatad2btm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Scaper Scapertm1b(EUCOMM)Hmgu |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote | male infertility | 0.0 | ||
4933430I17Rik 4933430I17Riktm1a(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Pancreas | homozygote | abnormal pancreas morphology | 0.0 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Hemoglobin | homozygote | decreased hemoglobin content | 0.0 | ||
Ino80 Ino80tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Cdk8 Cdk8tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Myo18b Myo18bem2(IMPC)Ics |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Cdk8 Cdk8tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E9.5 | Embryo Size | homozygote | abnormal embryo size | 0.0 | ||
Cdc26 Cdc26tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Cdk8 Cdk8tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E9.5 | Embryo turning | homozygote | abnormal embryo turning | 0.0 | ||
Dnal4 Dnal4tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Kidney | homozygote | abnormal kidney morphology | 0.0 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Gross Pathology and Tissue Collection | Pancreas | homozygote | abnormal pancreas morphology | 0.0 | ||
Il18rap Il18raptm1b(KOMP)Wtsi |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote | male infertility | 0.0 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Liver | homozygote | abnormal liver morphology | 0.0 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Small intestine | homozygote | abnormal ileum morphology | 0.0 | ||
Lcp2 Lcp2tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Setbp1 Setbp1tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Nol8 Nol8tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Viability E12.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to tooth bud stage | 0.0 | ||
Otub1 Otub1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Small intestine | homozygote | abnormal duodenum morphology | 0.0 | ||
Cfap119 Cfap119tm1b(EUCOMM)Hmgu |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote | male infertility | 0.0 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Bmp10 Bmp10tm3b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Large intestine | homozygote | abnormal colon morphology | 0.0 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Skin | homozygote | abnormal skin morphology | 0.0 | ||
Derl2 Derl2tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Spleen | homozygote | abnormal spleen morphology | 0.0 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Liver | homozygote | abnormal liver morphology | 0.0 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Viability E9.5 Secondary Screen | Outcome | homozygote | embryonic lethality prior to organogenesis | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 0.0 | ||
App Apptm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote | male infertility | 0.0 | ||
Pigu Pigutm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Cdk8 Cdk8tm1b(EUCOMM)Hmgu |
Gross Morphology Embryo E9.5 | Heart morphology | homozygote | abnormal heart morphology | 0.0 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Skin | homozygote | abnormal skin morphology | 0.0 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Large intestine | homozygote | abnormal colon morphology | 0.0 | ||
Pigu Pigutm1b(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Brain | heterozygote | hydrocephaly | 0.0 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Gross Pathology and Tissue Collection | Seminal vesicle | heterozygote | abnormal seminal vesicle morphology | 0.0 | ||
Zranb1 Zranb1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Fertility of Homozygous Knock-out Mice | Gross Findings Male | homozygote | male infertility | 0.0 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Gross Pathology and Tissue Collection | Spleen | hemizygote | abnormal spleen morphology | 0.0 | ||
Ncs1 Ncs1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Taf2 Taf2tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Chrna1 Chrna1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 0.0 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Lymph node | homozygote | enlarged lymph nodes | 0.0 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Hematology | Hemoglobin | homozygote | decreased hemoglobin content | 0.0 | ||
Nrp1 Nrp1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, complete penetrance | 0.0 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Gross Pathology and Tissue Collection | Spleen | homozygote | abnormal spleen morphology | 0.0 | ||
Ddr1 Ddr1tm1b(EUCOMM)Hmgu |
Viability Primary Screen | Viability Outcome | homozygote | preweaning lethality, incomplete penetrance | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Number of center entries | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Number of center entries | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Center distance travelled | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Center distance travelled | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Distance travelled - total | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Distance travelled - total | homozygote | hyperactivity | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 0.0 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 0.0 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 0.0 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery average speed | homozygote | hyperactivity | 4.203895392974451E-45 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 1.8216880036222622E-44 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 1.0411647589933391E-42 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 1.0875421329686332E-39 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 1.864587354809102E-39 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 5.253285773953377E-39 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 1.3557283783948205E-38 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery average speed | homozygote | hyperactivity | 3.535953868267848E-38 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 2.1072921367262833E-37 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 2.4479693173480584E-37 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 9.860238213675855E-37 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 2.9169064719992422E-36 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 5.8038953787305776E-36 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 1.2803895719987588E-35 | ||
Mmp9 Mmp9tm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 1.0479636600457573E-34 | ||
Mmp9 Mmp9tm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 6.394987274658277E-34 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 5.976280135821713E-33 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 3.392258642271044E-32 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 7.220984684671898E-31 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 7.651647728796218E-31 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 2.023420217245564E-29 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 8.138768694539684E-29 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 1.1064591560393089E-26 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 2.2881845787516442E-26 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Rotarod | Latency to fall mean | homozygote | abnormal motor capabilities/coordination/movement | 4.667917081851769E-26 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 4.819202114545693E-26 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 5.429913267315721E-26 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 3.576636179704176E-25 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.5838638814500744E-24 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 5.238827638155455E-24 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Center resting time | homozygote | decreased locomotor activity | 1.0856354264749499E-23 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Indirect Calorimetry | Total water intake | homozygote | increased fluid intake | 2.126859246163405E-23 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Periphery distance travelled | homozygote | hyperactivity | 6.586436987050518E-23 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Neutrophil cell count | heterozygote | increased neutrophil cell number | 6.62713589887268E-23 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery distance travelled | homozygote | hyperactivity | 6.929993484338959E-23 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 1.5212588071609038E-22 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 2.383193728189838E-22 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 3.039153911421945E-22 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 4.249933727030177E-22 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.0491675354080605E-21 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.0491675354080605E-21 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Unexpected behaviors | homozygote | abnormal behavior | 1.2448923825822975E-21 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Startle response | homozygote | abnormal startle reflex | 1.2448923825822975E-21 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Head bobbing | homozygote | head bobbing | 1.2448923825822975E-21 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 1.3934761137508772E-21 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Left outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 3.599089098509149E-21 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 3.984926445102872E-21 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 6.780931009264219E-21 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Periphery average speed | homozygote | hyperactivity | 4.8686849190848196E-20 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 7.77302138603963E-20 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Skin color - tail | homozygote | abnormal skin coloration | 1.0288792991421923E-19 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.1521206801125264E-19 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 1.188563026727345E-19 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Skin color - tail | homozygote | abnormal skin coloration | 1.2687735675038757E-19 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 3.704710353053496E-19 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 8.67409611066355E-19 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Lymphocyte cell count | homozygote | decreased lymphocyte cell number | 1.3920717654425346E-18 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.9423710387363E-18 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Aspartate aminotransferase | homozygote | increased circulating aspartate transaminase level | 2.2353795048082024E-18 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Number of rears - total | homozygote | increased vertical activity | 6.710502305746131E-18 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Open Field | Whole arena resting time | heterozygote | decreased locomotor activity | 6.854817198495807E-18 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Unexpected behaviors | homozygote | abnormal behavior | 1.0871313844706772E-17 | ||
Cav1 Cav1em2(IMPC)Ics |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 1.1318032734516035E-17 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alanine aminotransferase | heterozygote | increased circulating alanine transaminase level | 1.341372707646302E-17 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Right outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 2.3397574558393287E-17 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 2.6365683884690762E-17 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | hyperactivity | 5.1305288541005404E-17 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 5.560087716666268E-17 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 8.016723476953624E-17 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 8.448839320228876E-17 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Startle response | heterozygote | abnormal startle reflex | 1.0517514800083551E-16 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote | decreased prepulse inhibition | 1.149962634136776E-16 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | White blood cell count | homozygote | decreased leukocyte cell number | 1.334699461141755E-16 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Forelimb digit - shape | homozygote | abnormal digit morphology | 1.3729141466505208E-16 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Forelimb digit - size | homozygote | abnormal digit morphology | 1.3729141466505208E-16 | ||
Mmp9 Mmp9tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 2.26660219803518E-16 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery distance travelled | homozygote | hyperactivity | 2.4498953632606823E-16 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Open Field | Periphery resting time | heterozygote | decreased locomotor activity | 2.773340188125657E-16 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total protein | homozygote | decreased circulating total protein level | 3.766981568357672E-16 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 4.271703090638092E-16 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 7.23324897038553E-16 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Alkaline phosphatase | homozygote | decreased circulating alkaline phosphatase level | 1.1439427709806398E-15 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Startle response | homozygote | abnormal startle reflex | 1.2436783594209919E-15 | ||
Lat Latem1(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Startle response | homozygote | abnormal startle reflex | 1.2436783594209919E-15 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 1.8394885342997184E-15 | ||
Mmp9 Mmp9tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 2.580399688207843E-15 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Aspartate aminotransferase | homozygote | increased circulating aspartate transaminase level | 3.4528741170658734E-15 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Periphery distance travelled | homozygote | hyperactivity | 4.341682517520519E-15 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 4.805727400091419E-15 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | hyperactivity | 5.017197645702928E-15 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 5.510820071759001E-15 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 6.3298407924146545E-15 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 9.45195341401717E-15 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Neutrophil differential count | heterozygote | increased neutrophil cell number | 1.3382954548160284E-14 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Percentage center movement time | homozygote | decreased anxiety-related response | 1.645986949169731E-14 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 1.894321254491873E-14 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 2.4427340914443853E-14 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Lymphocyte cell count | homozygote | decreased lymphocyte cell number | 2.6594447604939668E-14 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte differential count | heterozygote | decreased lymphocyte cell number | 3.6284824699982926E-14 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Monocyte differential count | heterozygote | increased monocyte cell number | 3.9036394288479576E-14 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Center permanence time | homozygote | decreased thigmotaxis | 4.2363231385301667E-14 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Percentage center time | homozygote | abnormal behavior | 4.2363231385301667E-14 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery permanence time | homozygote | decreased thigmotaxis | 4.2363231385301667E-14 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 4.259833723827336E-14 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Cue freezing total | homozygote | abnormal cued conditioning behavior | 4.4615166731399106E-14 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 4.7024409648328824E-14 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 4.852094407140593E-14 | ||
Otub1 Otub1tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 5.952856751371277E-14 | ||
Mx2 Mx2em1(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Startle response | homozygote | abnormal startle reflex | 6.995690512339239E-14 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 7.078392776430076E-14 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 7.848864787274312E-14 | ||
Plscr1 Plscr1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 8.155033316388852E-14 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Eye Morphology | Retinal Blood Vessels Pattern | homozygote | abnormal retina blood vessel morphology | 8.416176962159141E-14 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Eye Morphology | Retinal Blood Vessels | homozygote | abnormal retina vasculature morphology | 8.416176962159141E-14 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Percentage center movement time | homozygote | decreased anxiety-related response | 1.4305188435724536E-13 | ||
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 1.5817928293148514E-13 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery resting time | homozygote | hyperactivity | 1.6415937619668197E-13 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote | decreased prepulse inhibition | 1.6937680099617103E-13 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 1.7428648856152723E-13 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Number of rears - total | hemizygote | increased vertical activity | 2.2681856393091948E-13 | ||
Dnajc5b Dnajc5btm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 2.5029579645875766E-13 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Center average speed | hemizygote | hyperactivity | 2.757793993168889E-13 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena resting time | homozygote | hyperactivity | 2.893459668910914E-13 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Left outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 3.1482745555498626E-13 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Unexpected behaviors | homozygote | abnormal behavior | 3.1925915904007507E-13 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Open Field | Number of rears - total | homozygote | increased vertical activity | 3.20858167509111E-13 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 3.2750432682644715E-13 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Alanine aminotransferase | heterozygote | increased circulating alanine transaminase level | 3.8915523364532745E-13 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 5.442431444749318E-13 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Albumin | heterozygote | increased circulating serum albumin level | 5.469784781358955E-13 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | HDL-cholesterol | homozygote | increased circulating HDL cholesterol level | 5.487832410722149E-13 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | short tibia | 6.516513132055757E-13 | ||
Gpr101 Gpr101tm1b(KOMP)Mbp |
Open Field | Center resting time | homozygote | decreased locomotor activity | 7.150222796660499E-13 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Left outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 9.22151244253655E-13 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 1.0099792096401883E-12 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 1.0994378150941397E-12 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Center average speed | homozygote | hyperactivity | 1.5796253194366727E-12 | ||
Cav1 Cav1em2(IMPC)Ics |
Clinical Chemistry | HDL-cholesterol | homozygote | increased circulating HDL cholesterol level | 1.6992862195489011E-12 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery resting time | homozygote | hyperactivity | 1.933653541105751E-12 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Monocyte cell count | heterozygote | increased monocyte cell number | 2.0805785479888206E-12 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 2.4865513294225483E-12 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 2.7195812875996372E-12 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Number of rears - total | homozygote | increased vertical activity | 2.720792124585869E-12 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Calcium | heterozygote | increased circulating calcium level | 2.8711072148218664E-12 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Periphery distance travelled | heterozygote | hyperactivity | 3.4245655356618387E-12 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | Alkaline phosphatase | homozygote | decreased circulating alkaline phosphatase level | 3.664896511268445E-12 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | White blood cell count | homozygote | decreased leukocyte cell number | 4.004995120265864E-12 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 4.297952618803613E-12 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean/Body weight | heterozygote | increased lean body mass | 4.5775232562772494E-12 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 4.702976289655547E-12 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Periphery average speed | heterozygote | hyperactivity | 5.300459290230597E-12 | ||
Iah1 Iah1tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | ST | homozygote | prolonged ST segment | 5.379882303535588E-12 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Percentage center time | homozygote | abnormal behavior | 6.485515683524179E-12 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Periphery permanence time | homozygote | decreased thigmotaxis | 6.485516550885917E-12 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Center permanence time | homozygote | decreased thigmotaxis | 6.485516550885917E-12 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Forepaw - shape | homozygote | abnormal autopod morphology | 6.845509402386707E-12 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Hindpaw - shape | homozygote | abnormal autopod morphology | 6.845509402386707E-12 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Whole arena average speed | heterozygote | hyperactivity | 7.966606541121024E-12 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote | decreased exploration in new environment | 8.005322099657874E-12 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote | decreased bone mineral content | 8.210415854137398E-12 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 9.04498698162115E-12 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 9.734890844825816E-12 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | decreased total body fat amount | 1.1687428802531485E-11 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 1.1969980562298588E-11 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 1.2105929106387414E-11 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Echo | LVAWd | heterozygote | increased heart left ventricle size | 1.468936777770935E-11 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote | abnormal coat/hair pigmentation | 1.6260062740691694E-11 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote | abnormal coat/hair pigmentation | 1.6260062740691694E-11 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | homozygote | abnormal coat/hair pigmentation | 1.6260062740691694E-11 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | long tibia | 1.7175027025584377E-11 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote | decreased prepulse inhibition | 1.7358578116577483E-11 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 2.2252866216376788E-11 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 2.241584695639176E-11 | ||
4933430I17Rik 4933430I17Riktm1b(EUCOMM)Wtsi |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 2.2638498714533384E-11 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Ears | homozygote | abnormal ear morphology | 2.2938565977237424E-11 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 2.7926905579733763E-11 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Aspartate aminotransferase | heterozygote | increased circulating aspartate transaminase level | 2.9574717674840656E-11 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Contact righting | homozygote | impaired righting response | 2.964814158068485E-11 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total protein | homozygote | decreased circulating total protein level | 3.0325731509295295E-11 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 3.09037101464682E-11 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Distance travelled - total | homozygote | hyperactivity | 3.1013542428626195E-11 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Distance travelled - total | homozygote | hyperactivity | 3.117961444587536E-11 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 3.268856019200683E-11 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Open Field | Whole arena resting time | heterozygote | decreased locomotor activity | 3.780276092157919E-11 | ||
Sdsl Sdsltm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 3.911630741537664E-11 | ||
Ctsd Ctsdtm1b(EUCOMM)Wtsi |
Clinical Chemistry | Aspartate aminotransferase | heterozygote | increased circulating aspartate transaminase level | 4.483953833234189E-11 | ||
Laptm4a Laptm4atm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 4.8071019387307956E-11 | ||
Spn Spnem1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | decreased lean body mass | 5.2523211474531095E-11 | ||
Mx2 Mx2em1(IMPC)Ics |
Eye Morphology | Left vitreous humour thickness | homozygote | abnormal vitreous body morphology | 5.2523905363921486E-11 | ||
Mx2 Mx2em1(IMPC)Ics |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 6.190106760506353E-11 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 7.851961442151278E-11 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat mass | heterozygote | decreased total body fat amount | 8.203211721014014E-11 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote | decreased prepulse inhibition | 8.81821907161573E-11 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Open Field | Periphery resting time | heterozygote | decreased locomotor activity | 9.545850221392982E-11 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote | decreased bone mineral density | 1.0728896937539645E-10 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 1.4436038475729163E-10 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Right outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 1.4487899768766965E-10 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Eye Morphology | Persistence of hyaloid vascular system | homozygote | persistence of hyaloid vascular system | 1.4498267864038183E-10 | ||
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 1.496106571963196E-10 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | HDL-cholesterol | heterozygote | increased circulating HDL cholesterol level | 1.5021917043611666E-10 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | homozygote | increased lymphocyte cell number | 1.5557861943182871E-10 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Hindlimb digit - size | homozygote | abnormal digit morphology | 1.6551701675915353E-10 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Hindlimb digit - shape | homozygote | abnormal digit morphology | 1.6551701675915353E-10 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 1.7578111188853995E-10 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Trunk curl | homozygote | trunk curl | 1.7720806766430286E-10 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Open Field | Center resting time | homozygote | decreased locomotor activity | 1.8211113173016713E-10 | ||
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 2.0787083165885178E-10 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Distance travelled - total | heterozygote | hyperactivity | 2.2562365864509104E-10 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 2.2754487183362926E-10 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 2.3693852435613394E-10 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | CD8 CD44+CD62L+ T cells | homozygote | increased effector memory CD8-positive, alpha-beta T cell number | 2.385627251300093E-10 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 2.583243063902785E-10 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Hematology | Neutrophil cell count | heterozygote | increased neutrophil cell number | 2.7102270427903363E-10 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Right outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 3.0085911539856625E-10 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 3.300276718576356E-10 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 3.332328579741528E-10 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 3.680311333464914E-10 | ||
Iah1 Iah1tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QT | homozygote | prolonged QT interval | 3.760875777469863E-10 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Area | homozygote | abnormal bone structure | 3.8036862548551653E-10 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Right vitreous humor thickness | homozygote | abnormal vitreous body morphology | 3.8751418740545773E-10 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Periphery permanence time | homozygote | decreased thigmotaxis | 4.1253769844651345E-10 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Center permanence time | homozygote | decreased thigmotaxis | 4.1253769844651345E-10 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Percentage center time | homozygote | abnormal behavior | 4.1253769844651345E-10 | ||
Lca5l Lca5lem1(IMPC)Ics |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 4.4191267312143623E-10 | ||
Il18rap Il18raptm1b(KOMP)Wtsi |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 4.5047315877511096E-10 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Whole arena average speed | homozygote | hyperactivity | 4.522342500479226E-10 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Distance travelled - total | hemizygote | hyperactivity | 4.533306785514668E-10 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Persistence of hyaloid vascular system | homozygote | persistence of hyaloid vascular system | 4.695331901061195E-10 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | White blood cell count | homozygote | increased leukocyte cell number | 5.161590044266973E-10 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.247645096240205E-10 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.247645096240205E-10 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Total cholesterol | heterozygote | increased circulating cholesterol level | 5.362487121018944E-10 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 5.733047370171107E-10 | ||
Gpr108 Gpr108tm1b(EUCOMM)Hmgu |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 6.030737020878973E-10 | ||
Bace2 Bace2tm1b(EUCOMM)Wtsi |
Eye Morphology | Retina (combined) | homozygote | abnormal retina morphology | 6.0517613142963E-10 | ||
Bace2 Bace2tm1b(EUCOMM)Wtsi |
Eye Morphology | Retina (combined) | homozygote | abnormal retina morphology | 6.0517613142963E-10 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Hematology | Lymphocyte differential count | heterozygote | decreased lymphocyte cell number | 6.070968172622315E-10 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 6.257327433978332E-10 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Periphery average speed | homozygote | hyperactivity | 6.27895457849803E-10 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Eosinophil differential count | homozygote | increased eosinophil cell number | 6.466169266694521E-10 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 6.876628710905663E-10 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Open Field | Distance travelled - total | heterozygote | decreased locomotor activity | 7.281253378010888E-10 | ||
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu |
Hematology | Eosinophil differential count | heterozygote | increased eosinophil cell number | 7.306667493267582E-10 | ||
Plscr1 Plscr1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 7.688067960032186E-10 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Immunophenotyping | Monocytes | homozygote | increased monocyte cell number | 7.837571702751234E-10 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean mass | heterozygote | increased lean body mass | 7.914163768774074E-10 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | HDL-cholesterol | heterozygote | increased circulating HDL cholesterol level | 9.137020029470477E-10 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | hyperactivity | 9.755614094331122E-10 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) differential count | homozygote | increased large unstained cell number | 9.99914151478265E-10 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Heart Weight | Heart weight | homozygote | increased heart weight | 1.00001806835337E-9 | ||
Spn Spnem1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | decreased lean body mass | 1.001115301768607E-9 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Heart Weight | Tibia length | heterozygote | short tibia | 1.0795613292202688E-9 | ||
Cdkl5 Cdkl5tm1dIcs |
Indirect Calorimetry | Respiratory Exchange Ratio | hemizygote | decreased respiratory quotient | 1.1501966046267853E-9 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Right inner nuclear layer | heterozygote | abnormal retina inner nuclear layer morphology | 1.2135205063046328E-9 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 1.2200976895471172E-9 | ||
Ppp4c Ppp4cem1(IMPC)Ics |
Heart Weight | Heart weight | heterozygote | increased heart weight | 1.2631135026808238E-9 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.2730342335842693E-9 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Gait | homozygote | abnormal gait | 1.2946215210973833E-9 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 1.3105607710173217E-9 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI1 | homozygote | decreased prepulse inhibition | 1.3384059416310379E-9 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 1.3574482649048036E-9 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 1.3921080954659715E-9 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 1.4852892249450633E-9 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Area | homozygote | abnormal bone structure | 1.5478007764357926E-9 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 1.5661322239068909E-9 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Hematology | Neutrophil differential count | heterozygote | increased neutrophil cell number | 1.7172321342684427E-9 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 1.747616495961779E-9 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 1.8449035632528421E-9 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | decreased total body fat amount | 1.9431791731250314E-9 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Aspartate aminotransferase | homozygote | increased circulating aspartate transaminase level | 1.964345797134115E-9 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 1.996602883025389E-9 | ||
Dgkk Dgkkem1(IMPC)Ics |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | hemizygote | increased startle reflex | 2.157661604940131E-9 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Whole arena average speed | heterozygote | hyperactivity | 2.182724445631834E-9 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 2.21953655454854E-9 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Forepaw - shape | homozygote | abnormal autopod morphology | 2.3473800681017565E-9 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Hindpaw - shape | homozygote | abnormal autopod morphology | 2.3473800681017565E-9 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 2.3561759210366517E-9 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | HDL-cholesterol | homozygote | increased circulating HDL cholesterol level | 2.411750577024918E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | homozygote | abnormal coat/hair pigmentation | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote | abnormal coat/hair pigmentation | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - head | homozygote | abnormal coat appearance | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - abdomen | homozygote | abnormal coat/hair pigmentation | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - abdomen | homozygote | abnormal coat appearance | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - head | homozygote | abnormal coat/hair pigmentation | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - back | homozygote | abnormal coat/hair pigmentation | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - back | homozygote | abnormal coat appearance | 2.6596547186841235E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote | abnormal coat/hair pigmentation | 2.6596547186841235E-9 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Eosinophil cell count | homozygote | increased eosinophil cell number | 2.7762587784252446E-9 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 2.7938702462648735E-9 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 2.796241238556263E-9 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Open Field | Whole arena average speed | heterozygote | decreased locomotor activity | 2.8360147563688543E-9 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - back | heterozygote | abnormal coat/hair pigmentation | 2.9527822409392E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - head | homozygote | abnormal coat/hair pigmentation | 2.9527822409392E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote | abnormal coat/hair pigmentation | 2.9527822409392E-9 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - head | heterozygote | abnormal coat/hair pigmentation | 2.9527822409392E-9 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration pre-cue-1 | homozygote | abnormal freezing behavior | 2.9711861859738065E-9 | ||
Spn Spnem1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | increased total body fat amount | 2.9960238734361155E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - head | homozygote | abnormal coat appearance | 3.0071478640536498E-9 | ||
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 3.0975824127921214E-9 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Periphery distance travelled | homozygote | decreased locomotor activity | 3.211877208642022E-9 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Whole arena resting time | homozygote | decreased locomotor activity | 3.3754108397232585E-9 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Eosinophil differential count | homozygote | increased eosinophil cell number | 3.4235518864278447E-9 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Periphery resting time | homozygote | decreased locomotor activity | 3.574183837784517E-9 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 3.780404878028776E-9 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Hematology | Neutrophil differential count | heterozygote | increased neutrophil cell number | 4.192350022691471E-9 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | decreased total body fat amount | 4.22727364224329E-9 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 4.303733369681595E-9 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Retina (combined) | homozygote | abnormal retina morphology | 4.311880186236294E-9 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 4.788188956439399E-9 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Total cholesterol | heterozygote | increased circulating cholesterol level | 4.933488728653401E-9 | ||
Tti2 Tti2tm1b(KOMP)Wtsi |
Hematology | Neutrophil differential count | heterozygote | increased neutrophil cell number | 5.006439263155471E-9 | ||
Dnajc5b Dnajc5btm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | ST | homozygote | shortened ST segment | 5.150420090416219E-9 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Open Field | Periphery average speed | heterozygote | decreased locomotor activity | 5.172031247724362E-9 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte differential count | heterozygote | decreased lymphocyte cell number | 5.3389688225990994E-9 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 5.675599989984903E-9 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 5.697122773540286E-9 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.748038489628016E-9 | ||
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.748038489628016E-9 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 6.037139677061987E-9 | ||
Tiam1 Tiam1tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 6.073993308319814E-9 | ||
Nol8 Nol8tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | increased startle reflex | 6.455358469992234E-9 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | homozygote | improved glucose tolerance | 6.469428104338704E-9 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Open Field | Periphery distance travelled | heterozygote | decreased locomotor activity | 6.5296275053583486E-9 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Number of rears - total | homozygote | decreased vertical activity | 6.773327676512508E-9 | ||
Icos Icostm2b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 7.024493875462667E-9 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 7.299575610630882E-9 | ||
Cx3cl1 Cx3cl1em3(IMPC)Ics |
Indirect Calorimetry | Respiratory Exchange Ratio | homozygote | increased respiratory quotient | 7.335291485333073E-9 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Eye Morphology | Retinal Blood Vessels | heterozygote | abnormal retina vasculature morphology | 7.359192810696413E-9 | ||
Gpr101 Gpr101tm1b(KOMP)Mbp |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 7.549342484480803E-9 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | hemizygote | abnormal auditory brainstem response | 7.59233031999429E-9 | ||
Lat Latem1(IMPC)Ics |
Eye Morphology | Left vitreous humour thickness | homozygote | abnormal vitreous body morphology | 7.601577145521787E-9 | ||
Cfap119 Cfap119tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 7.805172508312808E-9 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Indirect Calorimetry | Respiratory Exchange Ratio | homozygote | decreased respiratory quotient | 7.94413423932383E-9 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Distance travelled - total | homozygote | decreased locomotor activity | 8.158505870881072E-9 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Eye Morphology | Retinal Blood Vessels Pattern | heterozygote | abnormal retina blood vessel morphology | 8.360223624492846E-9 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 8.646287241731443E-9 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 8.7894704847713E-9 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 8.869236900466149E-9 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Periphery average speed | heterozygote | hyperactivity | 9.06601904659965E-9 | ||
Bnc2 Bnc2tm1b(KOMP)Wtsi |
Eye Morphology | Right corneal thickness | heterozygote | increased cornea thickness | 9.643667198133699E-9 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 9.75878844400313E-9 | ||
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 1.0030728248011656E-8 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Albumin | heterozygote | increased circulating serum albumin level | 1.0412567696960195E-8 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 1.0465715405416631E-8 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
X-ray | Shape of vertebrae | homozygote | abnormal vertebrae morphology | 1.1423186840886501E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 1.1613765948936816E-8 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | decreased lean body mass | 1.1835946445160062E-8 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Open Field | Number of rears - total | homozygote | increased vertical activity | 1.189023990377791E-8 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 1.191867315952777E-8 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Retina (combined) | homozygote | abnormal retina morphology | 1.2438028385020061E-8 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 1.3369698237397643E-8 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 1.3419038324968824E-8 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote | abnormal coat/hair pigmentation | 1.3729573034026998E-8 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | homozygote | abnormal coat/hair pigmentation | 1.3729573034026998E-8 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Distance travelled - total | heterozygote | hyperactivity | 1.389243831084741E-8 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 1.3913967755740941E-8 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) differential count | homozygote | decreased large unstained cell number | 1.4252796276537083E-8 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 1.4360749922559535E-8 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - abdomen | heterozygote | abnormal coat/hair pigmentation | 1.4709356399578155E-8 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 1.4713706697477846E-8 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 1.5828046429078313E-8 | ||
Cidea Cideatm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 1.597407006670437E-8 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | long tibia | 1.6825966397959746E-8 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Glucose | homozygote | decreased circulating glucose level | 1.69143667960725E-8 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 1.7043404909600213E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 1.7253768191949348E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Glucose | homozygote | increased circulating glucose level | 1.7264266460870203E-8 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.7580855882215474E-8 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 1.762307277886066E-8 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena resting time | homozygote | hyperactivity | 1.8029785664452902E-8 | ||
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 1.8568323767453876E-8 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | increased total body fat amount | 2.0230354280670326E-8 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | HDL-cholesterol | homozygote | decreased circulating HDL cholesterol level | 2.2655529008375197E-8 | ||
Plscr1 Plscr1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 2.2766332818946466E-8 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) count | heterozygote | increased large unstained cell number | 2.4343135507365332E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Albumin | homozygote | increased circulating serum albumin level | 2.4769725825990463E-8 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Locomotor activity | heterozygote | decreased exploration in new environment | 2.4817556010248154E-8 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 2.566681445159702E-8 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 2.6140730469137452E-8 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 2.6300012834212794E-8 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote | decreased exploration in new environment | 2.719067637713124E-8 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 2.731605164285611E-8 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Heart Weight | Heart weight | homozygote | increased heart weight | 2.7507153887995628E-8 | ||
Exd1 Exd1tm1b(EUCOMM)Hmgu |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 2.775146690225938E-8 | ||
Cfap119 Cfap119tm1b(EUCOMM)Hmgu |
Clinical Chemistry | HDL-cholesterol | homozygote | increased circulating HDL cholesterol level | 2.7754268216995115E-8 | ||
Dnajc5b Dnajc5btm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QT | homozygote | shortened QT interval | 2.7787640632936927E-8 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 2.9122547928750464E-8 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Platelet count | homozygote | thrombocytopenia | 2.940814169960504E-8 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 3.042586271817527E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 3.072842957863031E-8 | ||
Plekhg3 Plekhg3tm1b(EUCOMM)Hmgu |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 3.08445002872304E-8 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 3.114931956815781E-8 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QRS | homozygote | prolonged QRS complex duration | 3.340913679039659E-8 | ||
Gpr108 Gpr108tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | short tibia | 3.5430716138762364E-8 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 3.56657814393202E-8 | ||
Cd19 Cd19em2(IMPC)Ics |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 3.801267567382638E-8 | ||
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 3.902115253140437E-8 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Echo | HR | homozygote | increased heart rate | 3.9087034053864045E-8 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - abdomen | homozygote | abnormal coat/ hair morphology | 3.9608018198578065E-8 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Center average speed | heterozygote | hyperactivity | 4.118621532711586E-8 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 4.423364075023528E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 4.5944563709099384E-8 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) count | heterozygote | increased large unstained cell number | 4.6526828612059035E-8 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 4.741612613656798E-8 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 4.894411631539697E-8 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Platelet count | homozygote | thrombocytopenia | 4.899396444102422E-8 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote | abnormal coat/hair pigmentation | 4.9799950829765294E-8 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | homozygote | abnormal coat/hair pigmentation | 4.9799950829765294E-8 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote | abnormal coat/hair pigmentation | 4.9799950829765294E-8 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Alkaline phosphatase | homozygote | decreased circulating alkaline phosphatase level | 5.063615304834457E-8 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Number of center entries | homozygote | hyperactivity | 5.162498339927879E-8 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 5.3088147211610703E-8 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | short tibia | 5.418434056991828E-8 | ||
Bmp10 Bmp10tm3b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | heterozygote | improved glucose tolerance | 5.607490294323725E-8 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Glucose | homozygote | decreased circulating glucose level | 5.6364459766200525E-8 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | heterozygote | decreased bone mineral content | 5.636725930457942E-8 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Hindlimb nail - length | homozygote | abnormal nail morphology | 5.663578761527788E-8 | ||
App Apptm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 6.340549418837327E-8 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 6.47253699526118E-8 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Open Field | Distance travelled - total | heterozygote | decreased locomotor activity | 6.621592518740727E-8 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Left inner nuclear layer | heterozygote | abnormal retina inner nuclear layer morphology | 6.623172765785057E-8 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Eye Morphology | Right outer nuclear layer | heterozygote | abnormal retina outer nuclear layer morphology | 6.727538703898972E-8 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 6.819245612632585E-8 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Total protein | heterozygote | increased circulating total protein level | 7.081584385559836E-8 | ||
Plscr1 Plscr1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 7.089563069939686E-8 | ||
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 7.251400546692821E-8 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote | decreased bone mineral content | 7.506959320835449E-8 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) count | homozygote | decreased large unstained cell number | 7.658653089492873E-8 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 7.691717485158733E-8 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 7.742339391825226E-8 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Hemoglobin | homozygote | decreased hemoglobin content | 7.830052339841131E-8 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | HDL-cholesterol | homozygote | decreased circulating HDL cholesterol level | 7.925644496253881E-8 | ||
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 7.960113634908339E-8 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 8.107191717954265E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Eye Morphology | Right corneal thickness | homozygote | increased cornea thickness | 8.205006452044472E-8 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Eye Morphology | Corneal mineralization | heterozygote | abnormal cornea morphology | 8.267865325706225E-8 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Left vitreous humour thickness | homozygote | abnormal vitreous body morphology | 8.284136754355131E-8 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 8.345832469558445E-8 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI1 | homozygote | decreased prepulse inhibition | 8.470034629226575E-8 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 8.571471710183687E-8 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 8.682250296487837E-8 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 8.691230846125109E-8 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 8.737162460192849E-8 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 8.751996460887312E-8 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 8.83823432218378E-8 | ||
Med25 Med25tm1b(KOMP)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 8.919414540287107E-8 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 9.107942133823599E-8 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 9.136584822044824E-8 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - back | homozygote | abnormal coat/ hair morphology | 9.208552143036286E-8 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | hyperactivity | 9.249124133248188E-8 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Hematology | Hematocrit | homozygote | decreased hematocrit | 9.405405165807679E-8 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 9.438399217742699E-8 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 9.71577875930052E-8 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | BMC/Body weight | heterozygote | decreased bone mineral content | 9.735970252222614E-8 | ||
Cbl Cbltm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | PR | heterozygote | prolonged PR interval | 9.853454230324132E-8 | ||
Fut4 Fut4em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | decreased lean body mass | 1.0306480646704586E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | CD8 CD44+CD62L+ T cells | homozygote | increased effector memory CD8-positive, alpha-beta T cell number | 1.0417213047730911E-7 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | heterozygote | increased bone mineral density | 1.0507628189770912E-7 | ||
Phf8 Phf8tm1dIcs |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 1.0619596224614725E-7 | ||
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu |
Eye Morphology | Left anterior chamber depth | heterozygote | abnormal eye anterior chamber depth | 1.0750337509080055E-7 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 1.0871663391753827E-7 | ||
Ptpra Ptpratm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | increased startle reflex | 1.1447450276591553E-7 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 1.1617892425874743E-7 | ||
Ptafr Ptafrtm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.1709369829304705E-7 | ||
Gm12258 Gm12258tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.1734820759556897E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | Total protein | homozygote | decreased circulating total protein level | 1.2403192783949635E-7 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 1.3263048970202362E-7 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.3438665291687357E-7 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 1.3872666215775098E-7 | ||
Prrt2 Prrt2tm1b(KOMP)Wtsi |
Fear Conditioning | % Cue freezing total | homozygote | abnormal cued conditioning behavior | 1.3970135626095725E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 1.4291900640728272E-7 | ||
Epx Epxtm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | increased total body fat amount | 1.4968411221616407E-7 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 1.5024957633613667E-7 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 1.5117379348339455E-7 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) count | homozygote | increased large unstained cell number | 1.5447241707988724E-7 | ||
Dnm1l Dnm1ltm1b(KOMP)Wtsi |
Eye Morphology | Vitreous | heterozygote | abnormal vitreous body morphology | 1.5494228478019068E-7 | ||
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 1.5735480474177166E-7 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Eye Morphology | Persistence of hyaloid vascular system | heterozygote | persistence of hyaloid vascular system | 1.5794763896792574E-7 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Body length | heterozygote | decreased body length | 1.585747497756529E-7 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Immunophenotyping | NK Cells (panel B) | homozygote | decreased NK cell number | 1.626418111300154E-7 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Clinical Chemistry | HDL-cholesterol | heterozygote | decreased circulating HDL cholesterol level | 1.674753775660065E-7 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 1.687702706476557E-7 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) differential count | homozygote | decreased large unstained cell number | 1.6935425151132222E-7 | ||
Epx Epxtm1b(EUCOMM)Wtsi |
Clinical Chemistry | Triglycerides | homozygote | increased circulating triglyceride level | 1.756281591269726E-7 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Cue freezing total | homozygote | abnormal cued conditioning behavior | 1.7988890022024862E-7 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - abdomen | homozygote | abnormal coat appearance | 1.807482590265863E-7 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - head | homozygote | abnormal coat/ hair morphology | 1.807482590265863E-7 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - back | homozygote | abnormal coat appearance | 1.807482590265863E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - head | homozygote | abnormal coat/ hair morphology | 1.8350654329424287E-7 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 1.893416055054331E-7 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote | abnormal coat/hair pigmentation | 2.032969632637105E-7 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | decreased circulating alkaline phosphatase level | 2.055095507103033E-7 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Immunophenotyping | Eosinophils | homozygote | increased eosinophil cell number | 2.086218842123344E-7 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 2.1423811347176525E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 2.1701970354115474E-7 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 2.223028872094801E-7 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 2.2695599000144284E-7 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | White blood cell count | homozygote | increased leukocyte cell number | 2.3226920120578143E-7 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | T Cells (panel B) | heterozygote | increased T cell number | 2.3432983198290458E-7 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) differential count | homozygote | decreased large unstained cell number | 2.3436034268797812E-7 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 2.391167015503015E-7 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | homozygote | increased lymphocyte cell number | 2.3933185389068967E-7 | ||
Dnm1l Dnm1ltm1b(KOMP)Wtsi |
Eye Morphology | Persistence of hyaloid vascular system | heterozygote | persistence of hyaloid vascular system | 2.3983588448572846E-7 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 2.461762278471724E-7 | ||
Exd1 Exd1tm1b(EUCOMM)Hmgu |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 2.5062740860448685E-7 | ||
Laptm4a Laptm4atm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 2.5334870201731974E-7 | ||
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 2.5478374254817027E-7 | ||
Bmp10 Bmp10tm3b(EUCOMM)Hmgu |
Clinical Chemistry | Creatinine | heterozygote | decreased circulating creatinine level | 2.552330613525555E-7 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Creatinine | homozygote | decreased circulating creatinine level | 2.5772172307370056E-7 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | HDL-cholesterol | homozygote | decreased circulating HDL cholesterol level | 2.6362226890341844E-7 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 2.6681863118938054E-7 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | heterozygote | short tibia | 2.682641877527203E-7 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Body length | heterozygote | decreased body length | 2.685910942545888E-7 | ||
Bmp10 Bmp10tm3b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Locomotor activity | heterozygote | decreased exploration in new environment | 2.6874835157286725E-7 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 2.7285915393804316E-7 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Open Field | Periphery average speed | homozygote | hyperactivity | 2.837654164977721E-7 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Eye Morphology | Retinal Blood Vessels | heterozygote | abnormal retina vasculature morphology | 2.845895608061255E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote | decreased exploration in new environment | 2.8992093348279013E-7 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Gait | homozygote | abnormal gait | 2.899951994095318E-7 | ||
App Apptm1b(KOMP)Wtsi |
Eye Morphology | Right corneal thickness | heterozygote | increased cornea thickness | 2.9222300668152457E-7 | ||
Otub1 Otub1tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 2.9598660944429867E-7 | ||
Tubg1 Tubg1tm1dIcs |
Open Field | Center resting time | heterozygote | decreased locomotor activity | 2.9703807058467646E-7 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
Open Field | Center average speed | homozygote | hyperactivity | 3.0245709581322444E-7 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 3.0399692718674487E-7 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 3.091325879722717E-7 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 3.096585885487002E-7 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 3.12577384420365E-7 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Eye Morphology | Persistence of hyaloid vascular system | homozygote | persistence of hyaloid vascular system | 3.192790813955071E-7 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | decreased startle reflex | 3.2485627343703527E-7 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Periphery distance travelled | homozygote | hyperactivity | 3.313154763873172E-7 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 3.3151400202768855E-7 | ||
Coq6 Coq6tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | heterozygote | increased fasting circulating glucose level | 3.556855006081605E-7 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 3.574930929062248E-7 | ||
Trpm6 Trpm6tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Body length | heterozygote | increased body length | 3.6249022627998784E-7 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat/Body weight | heterozygote | decreased total body fat amount | 3.650161204404867E-7 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Whole arena average speed | hemizygote | hyperactivity | 3.669634054404014E-7 | ||
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 3.6884520682178845E-7 | ||
Prkdc Prkdcem2(IMPC)Ics |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 3.7087878013153386E-7 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Periphery distance travelled | hemizygote | hyperactivity | 3.764818075069343E-7 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Open Field | Number of center entries | heterozygote | hyperactivity | 3.784347200053162E-7 | ||
Rnf144b Rnf144btm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 3.796421026436292E-7 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Periphery distance travelled | homozygote | decreased locomotor activity | 3.8338293961714953E-7 | ||
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 4.109633664484136E-7 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 4.175863637101429E-7 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 4.2286822576897976E-7 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Fear Conditioning | % Pre-cue freezing total | homozygote | abnormal freezing behavior | 4.274642435575515E-7 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | T Cells (panel B) | heterozygote | increased T cell number | 4.2769386254803976E-7 | ||
Fut4 Fut4em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | increased total body fat amount | 4.3324050125193025E-7 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Indirect Calorimetry | Total food intake | homozygote | increased food intake | 4.404495541621145E-7 | ||
Lcp2 Lcp2tm1b(KOMP)Wtsi |
Eye Morphology | Lens Opacity | heterozygote | cataract | 4.408056213378586E-7 | ||
Lcp2 Lcp2tm1b(KOMP)Wtsi |
Eye Morphology | Lens | heterozygote | abnormal lens morphology | 4.408056213378586E-7 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Body length | homozygote | increased body length | 4.4484690420176776E-7 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 4.629335705885751E-7 | ||
Rwdd3 Rwdd3tm1b(KOMP)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | heterozygote | decreased grip strength | 4.650638061320933E-7 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Echo | Fractional Shortening | homozygote | increased cardiac muscle contractility | 4.747177797526092E-7 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 4.776709374709753E-7 | ||
Lat Latem1(IMPC)Ics |
Eye Morphology | Right vitreous humor thickness | homozygote | abnormal vitreous body morphology | 4.826097210752778E-7 | ||
Kif5c Kif5ctm1dIcs |
Hematology | Eosinophil differential count | heterozygote | increased eosinophil cell number | 4.923365395370638E-7 | ||
Arhgap24 Arhgap24tm1b(KOMP)Wtsi |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 4.950533707415161E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 4.977247272108798E-7 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Creatinine | homozygote | increased circulating creatinine level | 4.994636810806696E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - abdomen | homozygote | abnormal coat/hair pigmentation | 5.120124342283816E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - abdomen | homozygote | abnormal coat appearance | 5.120124342283816E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - back | homozygote | abnormal coat/hair pigmentation | 5.120124342283816E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - back | homozygote | abnormal coat appearance | 5.120124342283816E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - abdomen | homozygote | abnormal coat/hair pigmentation | 5.120124342283816E-7 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Heart Weight | Tibia length | homozygote | short tibia | 5.125520488036273E-7 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 5.144844976712193E-7 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Combined SHIRPA and Dysmorphology | Locomotor activity | hemizygote | increased exploration in new environment | 5.148951913724886E-7 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 5.186992098060728E-7 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Hematology | Eosinophil differential count | homozygote | increased eosinophil cell number | 5.195267362978484E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote | abnormal coat/hair pigmentation | 5.208298716752324E-7 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | hyperactivity | 5.231919431025744E-7 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right corneal thickness | homozygote | decreased cornea thickness | 5.275433636597882E-7 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Eye Morphology | Vitreous | heterozygote | abnormal vitreous body morphology | 5.306943080540805E-7 | ||
App Apptm1b(KOMP)Wtsi |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | heterozygote | increased blood urea nitrogen level | 5.405852903095365E-7 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 5.538700520446582E-7 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Eye Morphology | Retina (combined) | heterozygote | abnormal retina morphology | 5.599360974883894E-7 | ||
Elk3 Elk3em1(IMPC)Ics |
Clinical Chemistry | Total cholesterol | heterozygote | increased circulating cholesterol level | 5.611472602140566E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.69224880564434E-7 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 5.697789902114891E-7 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 5.811605774397322E-7 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.882051823391521E-7 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Periphery distance travelled | heterozygote | hyperactivity | 5.914410508012224E-7 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 5.999696668368415E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Open Field | Whole arena resting time | homozygote | decreased locomotor activity | 6.064610147404892E-7 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Startle response | homozygote | abnormal startle reflex | 6.271795882639708E-7 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 6.313322273854283E-7 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
X-ray | Digit integrity | homozygote | abnormal digit morphology | 6.39698441773362E-7 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Activity (body position) | homozygote | abnormal locomotor behavior | 6.720496799061948E-7 | ||
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | short tibia | 6.738858360222366E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Open Field | Distance travelled - total | homozygote | decreased locomotor activity | 6.766816227354866E-7 | ||
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 7.01588248830376E-7 | ||
Taf2 Taf2tm1b(EUCOMM)Hmgu |
Open Field | Center resting time | heterozygote | hyperactivity | 7.102210588527669E-7 | ||
Elk3 Elk3em1(IMPC)Ics |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 7.179959311542916E-7 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | decreased circulating total protein level | 7.202187362054246E-7 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Cholesterol ratio | homozygote | abnormal cholesterol homeostasis | 7.203021255008935E-7 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 7.376144708359789E-7 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Tremor | homozygote | tremors | 7.401316111099732E-7 | ||
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 7.475833285752742E-7 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Open Field | Center average speed | heterozygote | decreased locomotor activity | 7.54309041894885E-7 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) differential count | heterozygote | decreased large unstained cell number | 7.550042369075527E-7 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 7.572434128633176E-7 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Hematology | Lymphocyte cell count | heterozygote | decreased lymphocyte cell number | 7.636984378223133E-7 | ||
Spn Spnem1(IMPC)Ics |
Eye Morphology | Right corneal thickness | homozygote | increased cornea thickness | 7.721131964899541E-7 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
X-ray | Digit integrity | heterozygote | abnormal digit morphology | 7.982161491781881E-7 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Activity (body position) | homozygote | abnormal locomotor behavior | 8.002277809282532E-7 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 8.03565967544273E-7 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 8.333628898071765E-7 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 8.414430112679838E-7 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Lean mass | heterozygote | increased lean body mass | 8.472858894492674E-7 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 8.61330704537977E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Open Field | Periphery resting time | homozygote | decreased locomotor activity | 8.691341122357699E-7 | ||
Lat Latem1(IMPC)Ics |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 8.917079412640305E-7 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - head | homozygote | abnormal coat appearance | 8.943517855186656E-7 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - back | homozygote | abnormal coat/ hair morphology | 8.943517855186656E-7 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) differential count | heterozygote | decreased large unstained cell number | 9.046194122674933E-7 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Hematology | Hemoglobin | homozygote | decreased hemoglobin content | 9.378043159813387E-7 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat mass | heterozygote | decreased total body fat amount | 9.437638937015436E-7 | ||
Dnal4 Dnal4tm1b(EUCOMM)Wtsi |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 9.603629678167636E-7 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Open Field | Number of rears - total | homozygote | increased vertical activity | 9.608367008695495E-7 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 9.660573141445639E-7 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | gd T cells | homozygote | immune system phenotype | 9.677695516074891E-7 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 9.932502962328726E-7 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Hematology | Hematocrit | homozygote | increased hematocrit | 9.952468644769397E-7 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 1.0176295290875714E-6 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) differential count | homozygote | increased large unstained cell number | 1.0328834605388693E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 1.0336755167372758E-6 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Heart Weight | Heart weight | heterozygote | increased heart weight | 1.065686433321389E-6 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Eye Morphology | Retinal Blood Vessels Pattern | heterozygote | abnormal retina blood vessel morphology | 1.069949462362274E-6 | ||
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 1.073990006261738E-6 | ||
Cx3cl1 Cx3cl1em3(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote | decreased exploration in new environment | 1.0777854413390742E-6 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Clinical Chemistry | Total cholesterol | heterozygote | decreased circulating cholesterol level | 1.0944671657853178E-6 | ||
Ptafr Ptafrtm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.1277335261183907E-6 | ||
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total protein | heterozygote | increased circulating total protein level | 1.1437239209044492E-6 | ||
Tti2 Tti2tm1b(KOMP)Wtsi |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 1.187523707812943E-6 | ||
Tmem50b Tmem50btm1b(EUCOMM)Wtsi |
Eye Morphology | Right vitreous humor thickness | homozygote | abnormal vitreous body morphology | 1.1888519111380447E-6 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 1.1916253015442635E-6 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Indirect Calorimetry | Total water intake | homozygote | increased fluid intake | 1.2325664329182473E-6 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Locomotor activity | heterozygote | decreased exploration in new environment | 1.2493011354308692E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
X-ray | Digit integrity | homozygote | abnormal digit morphology | 1.276476950806682E-6 | ||
Bnc2 Bnc2tm1b(KOMP)Wtsi |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 1.2781785017068614E-6 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 1.2947266441187821E-6 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | hemizygote | abnormal auditory brainstem response | 1.3014692967772135E-6 | ||
Dyrk2 Dyrk2em1(IMPC)Ics |
Hematology | Large Unstained Cell (LUC) differential count | heterozygote | decreased large unstained cell number | 1.3083896419630037E-6 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 1.3150927316019079E-6 | ||
Tmem50b Tmem50btm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 1.317814962931152E-6 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Open Field | Periphery distance travelled | heterozygote | decreased locomotor activity | 1.318218437518226E-6 | ||
Stradb Stradbtm1b(KOMP)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 1.3284976603245013E-6 | ||
Hmgn1 Hmgn1em1(IMPC)Ics |
Indirect Calorimetry | Total food intake | homozygote | decreased food intake | 1.3710453004023293E-6 | ||
Laptm4a Laptm4atm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | ST | homozygote | prolonged ST segment | 1.3727531040785834E-6 | ||
Gm12258 Gm12258tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | increased startle reflex | 1.3758241266259574E-6 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Cholesterol ratio | homozygote | abnormal cholesterol homeostasis | 1.402817474627227E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - head | homozygote | abnormal coat/ hair morphology | 1.4188551631377777E-6 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 1.4487725366052473E-6 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 1.4553442042597453E-6 | ||
Taf2 Taf2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | HDL-cholesterol | heterozygote | increased circulating HDL cholesterol level | 1.4868127209410886E-6 | ||
Arhgap24 Arhgap24tm1b(KOMP)Wtsi |
Echo | LVAWd | homozygote | increased heart left ventricle size | 1.4876683280817815E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 1.5139245306272642E-6 | ||
Dpp4 Dpp4tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.5198659184534336E-6 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | heterozygote | decreased prepulse inhibition | 1.5452504840141046E-6 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 1.6165367924259044E-6 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote | decreased bone mineral density | 1.6165630540854181E-6 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total cholesterol | heterozygote | increased circulating cholesterol level | 1.6190562064366532E-6 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | DN NKT cells | heterozygote | increased CD4-negative NK T cell number | 1.6260189568129135E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI1 | homozygote | decreased prepulse inhibition | 1.6516416962986114E-6 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | homozygote | increased lymphocyte cell number | 1.6843788444020902E-6 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Periphery average speed | homozygote | hyperactivity | 1.7286522506765323E-6 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 1.7442625903640874E-6 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | heterozygote | short tibia | 1.804004000405257E-6 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Clinical Chemistry | Total bilirubin | heterozygote | increased circulating bilirubin level | 1.8252621885039844E-6 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 1.826915877245483E-6 | ||
Dusp11 Dusp11tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Activity (body position) | homozygote | abnormal locomotor behavior | 1.8300906958756968E-6 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | decreased lean body mass | 1.8631778857525205E-6 | ||
Hrh4 Hrh4tm1b(EUCOMM)Hmgu |
Eye Morphology | Right corneal thickness | homozygote | increased cornea thickness | 1.875514499261044E-6 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Body length | heterozygote | decreased body length | 1.8840262328012614E-6 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Open Field | Distance travelled - total | heterozygote | decreased locomotor activity | 1.9044662167289061E-6 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | decreased circulating total protein level | 1.9046016177526326E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Forelimb nail - length | homozygote | abnormal nail morphology | 1.919323949550744E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Hindlimb digit - size | homozygote | abnormal digit morphology | 1.919323949550744E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Forelimb digit - size | homozygote | abnormal digit morphology | 1.919323949550744E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Forelimb digit - shape | homozygote | abnormal digit morphology | 1.919323949550744E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Hindlimb digit - shape | homozygote | abnormal digit morphology | 1.919323949550744E-6 | ||
Iah1 Iah1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | decreased circulating alkaline phosphatase level | 1.9391993646422634E-6 | ||
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 1.9575520582293393E-6 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 1.9733511180675123E-6 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Tremor | heterozygote | tremors | 1.9958692973887082E-6 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | decreased lean body mass | 1.9973217604274396E-6 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 2.016467306020786E-6 | ||
Scaper Scapertm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 2.0174309156573145E-6 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 2.018432041950291E-6 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | heterozygote | increased fasting circulating glucose level | 2.0242828213667963E-6 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Tail - morphology | homozygote | abnormal tail morphology | 2.0391914858919336E-6 | ||
Ttc39a Ttc39atm1b(KOMP)Mbp |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 2.0449426756385947E-6 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 2.055716095128446E-6 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Heart Weight | Heart weight | homozygote | increased heart weight | 2.070240498142084E-6 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Optic Disc | homozygote | abnormal optic disk morphology | 2.0753368517034687E-6 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Immunophenotyping | CD8 CD44+CD62L+ T cells | homozygote | increased effector memory CD8-positive, alpha-beta T cell number | 2.0760671759489924E-6 | ||
Ackr3 Ackr3tm2b(EUCOMM)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | heterozygote | decreased grip strength | 2.086372887788457E-6 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 2.1135977021913277E-6 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Left outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 2.1140306216693716E-6 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) differential count | heterozygote | increased large unstained cell number | 2.1268369891913608E-6 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | DN NKT cells | heterozygote | increased CD4-negative NK T cell number | 2.140382093784865E-6 | ||
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi |
Eye Morphology | Right vitreous humor thickness | homozygote | abnormal vitreous body morphology | 2.1755863599537406E-6 | ||
Spn Spnem1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | increased total body fat amount | 2.180137244067737E-6 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 2.188335429309518E-6 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Eye Morphology | Left inner nuclear layer | heterozygote | abnormal retina inner nuclear layer morphology | 2.189220367654343E-6 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Hematology | Eosinophil cell count | heterozygote | increased eosinophil cell number | 2.293515308338101E-6 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 2.356562390559702E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 2.381013473495841E-6 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 2.3892334866104648E-6 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Cholesterol ratio | homozygote | abnormal cholesterol homeostasis | 2.4033263343881117E-6 | ||
Ncs1 Ncs1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 2.416763663859456E-6 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | ST | heterozygote | prolonged ST segment | 2.4520377337466925E-6 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 2.4553603452659445E-6 | ||
Fut4 Fut4em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | increased total body fat amount | 2.4900118660298176E-6 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Number of rears - total | homozygote | decreased vertical activity | 2.4981864044093527E-6 | ||
Gemin4 Gemin4em1(IMPC)Ics |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 2.523494913475588E-6 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Open Field | Number of rears - total | homozygote | increased vertical activity | 2.5394272142875707E-6 | ||
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi |
Hematology | Eosinophil differential count | homozygote | increased eosinophil cell number | 2.589377800177317E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Head morphology | homozygote | abnormal head morphology | 2.6015634375653462E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | NK Subsets (Q4) | homozygote | increased Ly6C-positive mature NK cell number | 2.609350531201926E-6 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Electrocardiogram (ECG) | PR | homozygote | prolonged PR interval | 2.6125594558834564E-6 | ||
Fut4 Fut4em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | decreased lean body mass | 2.6334039375797147E-6 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Center distance travelled | homozygote | hyperactivity | 2.6556056127446936E-6 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 2.7609373773884727E-6 | ||
Cav1 Cav1em2(IMPC)Ics |
Hematology | Hemoglobin | homozygote | increased hemoglobin content | 2.79375194622844E-6 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) count | homozygote | increased large unstained cell number | 2.7947673970629694E-6 | ||
Saxo1 Saxo1tm1b(EUCOMM)Hmgu |
Open Field | Periphery average speed | homozygote | hyperactivity | 2.8198905965837184E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 2.8232225304236636E-6 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Basophil cell count | homozygote | increased basophil cell number | 2.833442067640135E-6 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 2.8400033897924004E-6 | ||
Lmna Lmnatm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | heterozygote | improved glucose tolerance | 2.8460960947995773E-6 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QRS | heterozygote | prolonged QRS complex duration | 2.913172011176357E-6 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Aggression | homozygote | increased aggression | 2.9847378755221143E-6 | ||
Spn Spnem1(IMPC)Ics |
X-ray | Tibia length | homozygote | long tibia | 2.9977345548104495E-6 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI1 | homozygote | increased prepulse inhibition | 3.0412084015551955E-6 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Rotarod | Latency to fall mean | heterozygote | abnormal motor capabilities/coordination/movement | 3.0495541523123393E-6 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Heart Weight | Heart weight | homozygote | decreased heart weight | 3.0719959340785863E-6 | ||
Pax4 Pax4tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Tremor | heterozygote | tremors | 3.135042788926512E-6 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 3.1744807529321406E-6 | ||
Rnf144b Rnf144btm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Vocalization | homozygote | abnormal vocalization | 3.233821644244017E-6 | ||
Phf8 Phf8tm1dIcs |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 3.2458708574267803E-6 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Phosphorus | heterozygote | increased circulating phosphate level | 3.2609821118967375E-6 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Open Field | Center resting time | homozygote | decreased locomotor activity | 3.2775913041405147E-6 | ||
Cbl Cbltm1b(EUCOMM)Hmgu |
Echo | LVPWd | heterozygote | thick ventricular wall | 3.2887414818105754E-6 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Eye Morphology | Left inner nuclear layer | homozygote | abnormal retina inner nuclear layer morphology | 3.2906064006965607E-6 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Limb grasp | heterozygote | limb grasping | 3.3002932013914688E-6 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Open Field | Whole arena average speed | homozygote | decreased locomotor activity | 3.346690618855064E-6 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | heterozygote | short tibia | 3.3707149214023957E-6 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Combined SHIRPA and Dysmorphology | Aggression | hemizygote | increased aggression | 3.3822971090557985E-6 | ||
Ddr1 Ddr1tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | heterozygote | hyperactivity | 3.4390732253086753E-6 | ||
Cx3cl1 Cx3cl1em3(IMPC)Ics |
Open Field | Whole arena average speed | homozygote | decreased locomotor activity | 3.4431552649039077E-6 | ||
Lat Latem1(IMPC)Ics |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 3.478250164334895E-6 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Tremor | homozygote | tremors | 3.5466964618535712E-6 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 3.565210136002861E-6 | ||
Lca5l Lca5lem1(IMPC)Ics |
Hematology | Platelet count | homozygote | thrombocytopenia | 3.6020896914124023E-6 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total protein | homozygote | decreased circulating total protein level | 3.6182730127620744E-6 | ||
Ncam2 Ncam2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote | decreased exploration in new environment | 3.6406968320079613E-6 | ||
Prkdc Prkdcem2(IMPC)Ics |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 3.7090342175361E-6 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Hematology | Hemoglobin | heterozygote | decreased hemoglobin content | 3.709297743625939E-6 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Aspartate aminotransferase | homozygote | increased circulating aspartate transaminase level | 3.7093723221914843E-6 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 3.7547827105299802E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 3.8142657103890087E-6 | ||
Satb1 Satb1tm1b(EUCOMM)Hmgu |
Eye Morphology | Vitreous | heterozygote | abnormal vitreous body morphology | 3.814830961346161E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | CD8 T cells | homozygote | decreased CD8-positive, alpha-beta T cell number | 3.883155386574799E-6 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | homozygote | improved glucose tolerance | 3.89331808037241E-6 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Aggression | heterozygote | increased aggression | 3.900528099620715E-6 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 3.901811396644916E-6 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 3.901811396644916E-6 | ||
Arhgap24 Arhgap24tm1b(KOMP)Wtsi |
Echo | LVAWd | homozygote | increased heart left ventricle size | 3.92667789128609E-6 | ||
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration context-1 | homozygote | abnormal contextual conditioning behavior | 4.024737336294493E-6 | ||
Cd19 Cd19em2(IMPC)Ics |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 4.110589543415699E-6 | ||
Saxo1 Saxo1tm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 4.13208408645005E-6 | ||
Septin3 Septin3tm1b(KOMP)Wtsi |
Clinical Chemistry | Phosphorus | heterozygote | decreased circulating phosphate level | 4.134958089707652E-6 | ||
Coq6 Coq6tm1b(EUCOMM)Hmgu |
Eye Morphology | Persistence of hyaloid vascular system | heterozygote | persistence of hyaloid vascular system | 4.1767598304431885E-6 | ||
Dgkk Dgkkem1(IMPC)Ics |
Grip Strength | Forelimb grip strength normalised against body weight | hemizygote | decreased grip strength | 4.1984926610894036E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | NK cells (panel A) | homozygote | decreased NK cell number | 4.239067948219599E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote | decreased prepulse inhibition | 4.303282821638277E-6 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Hemoglobin | heterozygote | decreased hemoglobin content | 4.3586173887888435E-6 | ||
Rwdd3 Rwdd3tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | decreased grip strength | 4.364622327557299E-6 | ||
Laptm4a Laptm4atm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 4.3962031668343116E-6 | ||
Dpp4 Dpp4tm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | homozygote | decreased lymphocyte cell number | 4.408296717883786E-6 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | increased startle reflex | 4.458388048078632E-6 | ||
Myo18b Myo18bem2(IMPC)Ics |
Clinical Chemistry | Triglycerides | heterozygote | increased circulating triglyceride level | 4.572536454361398E-6 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Right outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 4.578718744596699E-6 | ||
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 4.5982719711901154E-6 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Open Field | Center distance travelled | homozygote | decreased locomotor activity | 4.711928340839222E-6 | ||
Fut4 Fut4em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote | increased bone mineral content | 4.800440819963114E-6 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Tremor | homozygote | tremors | 4.8187362153839786E-6 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Combined SHIRPA and Dysmorphology | Vocalization | hemizygote | abnormal vocalization | 4.840011115447851E-6 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 4.910171355732018E-6 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 4.92008348373929E-6 | ||
Lca5l Lca5lem1(IMPC)Ics |
Hematology | Platelet count | homozygote | thrombocytopenia | 4.92793196826824E-6 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | decreased grip strength | 5.014490398025373E-6 | ||
Dgkk Dgkkem1(IMPC)Ics |
Clinical Chemistry | Total cholesterol | hemizygote | increased circulating cholesterol level | 5.020877324568573E-6 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 5.056197096564574E-6 | ||
Rrp1b Rrp1btm2b(EUCOMM)Hmgu |
Eye Morphology | Vitreous | homozygote | abnormal vitreous body morphology | 5.082010829937644E-6 | ||
Ncam2 Ncam2tm1b(EUCOMM)Hmgu |
Hematology | Eosinophil cell count | homozygote | increased eosinophil cell number | 5.173280896997312E-6 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 5.203052751312498E-6 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | increased total body fat amount | 5.240900009084726E-6 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Clinical Chemistry | Alkaline phosphatase | homozygote | decreased circulating alkaline phosphatase level | 5.249355126579758E-6 | ||
Kctd15 Kctd15tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Creatinine | heterozygote | increased circulating creatinine level | 5.353321284928825E-6 | ||
Saxo1 Saxo1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | hyperactivity | 5.396801043389132E-6 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 5.4886177167645656E-6 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | decreased lean body mass | 5.685685664502671E-6 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 5.693322691513458E-6 | ||
Otub1 Otub1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | heterozygote | decreased bone mineral content | 5.734601018048124E-6 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 5.780190349469194E-6 | ||
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 5.8448067647987045E-6 | ||
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 5.863165370101342E-6 | ||
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi |
Fear Conditioning | % Context freezing total | heterozygote | abnormal contextual conditioning behavior | 5.883209269086365E-6 | ||
Clec9a Clec9atm1b(KOMP)Wtsi |
Echo | Fractional Shortening | homozygote | decreased cardiac muscle contractility | 5.897134087717859E-6 | ||
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
Open Field | Center resting time | homozygote | hyperactivity | 5.916313511988847E-6 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration context-2 | homozygote | abnormal contextual conditioning behavior | 6.004003353154985E-6 | ||
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi |
Fear Conditioning | Context freezing total | heterozygote | abnormal contextual conditioning behavior | 6.007631782267708E-6 | ||
Dpp4 Dpp4tm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 6.073160875530448E-6 | ||
Nlk Nlktm2b(KOMP)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 6.087720976211131E-6 | ||
Prrt2 Prrt2tm1b(KOMP)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 6.146346095192712E-6 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 6.230770395632135E-6 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | decreased circulating calcium level | 6.2463077483698726E-6 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 6.2600665842182934E-6 | ||
Enpp4 Enpp4em1(IMPC)Ics |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 6.268675406317925E-6 | ||
Gpr108 Gpr108tm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 6.382630544976564E-6 | ||
Tgif2 Tgif2tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Calcium | heterozygote | decreased circulating calcium level | 6.4405821831314825E-6 | ||
Cdk8 Cdk8tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 6.483353445219109E-6 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | heterozygote | increased prepulse inhibition | 6.521358955069445E-6 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Lean/Body weight | heterozygote | increased lean body mass | 6.642541393375723E-6 | ||
Trpm6 Trpm6tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | increased grip strength | 6.654313438048121E-6 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | DN CD44+CD62L- NKT cells | heterozygote | increased memory-marker CD4-negative NK T cell number | 6.657599897152977E-6 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Center permanence time | homozygote | increased thigmotaxis | 6.684907020826358E-6 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Percentage center time | homozygote | abnormal behavior | 6.684907020826358E-6 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Periphery permanence time | homozygote | increased thigmotaxis | 6.704263341816841E-6 | ||
Gp6 Gp6tm2b(EUCOMM)Hmgu |
Hematology | Lymphocyte cell count | homozygote | increased lymphocyte cell number | 6.713715265505016E-6 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 6.719562406942714E-6 | ||
Ncam2 Ncam2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 6.728859716531588E-6 | ||
Mtmr12 Mtmr12tm1b(KOMP)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 6.810686500102747E-6 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Eye Morphology | Right inner nuclear layer | homozygote | abnormal retina inner nuclear layer morphology | 6.823608146078186E-6 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Hematology | Hemoglobin | homozygote | increased hemoglobin content | 6.843039955128916E-6 | ||
Klf12 Klf12tm1b(EUCOMM)Wtsi |
Eye Morphology | Right corneal thickness | heterozygote | increased cornea thickness | 6.8793683567491826E-6 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 7.083445780153852E-6 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 7.3386427175137214E-6 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 7.431784524669638E-6 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Center distance travelled | homozygote | decreased locomotor activity | 7.436898613377707E-6 | ||
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 7.502151220251108E-6 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - head | homozygote | abnormal coat appearance | 7.624357294844231E-6 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - abdomen | homozygote | abnormal coat appearance | 7.624357294844231E-6 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair texture / appearance - back | homozygote | abnormal coat appearance | 7.624357294844231E-6 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - head | homozygote | abnormal coat/ hair morphology | 7.624357294844231E-6 | ||
Dbn1 Dbn1tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | decreased grip strength | 7.720507710473612E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 7.721248948655557E-6 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI1 | homozygote | increased prepulse inhibition | 7.751234079478309E-6 | ||
Exd1 Exd1tm1b(EUCOMM)Hmgu |
Heart Weight | Heart weight | homozygote | increased heart weight | 7.81233211455401E-6 | ||
Nfatc2ip Nfatc2ipem1(IMPC)Ics |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 7.85985048423754E-6 | ||
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 7.877544703660533E-6 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | heterozygote | improved glucose tolerance | 7.931711479614023E-6 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Clinical Chemistry | HDL-cholesterol | homozygote | increased circulating HDL cholesterol level | 8.147690095938742E-6 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Hematology | Mean cell volume | heterozygote | decreased mean corpuscular volume | 8.171374247467611E-6 | ||
Spn Spnem1(IMPC)Ics |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 8.203556717489846E-6 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Retina (combined) | homozygote | abnormal retina morphology | 8.27880921860924E-6 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | heterozygote | decreased total body fat amount | 8.465241080557462E-6 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 8.49367006594548E-6 | ||
Ect2 Ect2tm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb grip strength measurement mean | heterozygote | decreased grip strength | 8.630963748146314E-6 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 8.739164513826836E-6 | ||
Dync1h1 Dync1h1tm1dIcs |
Open Field | Center resting time | heterozygote | decreased locomotor activity | 8.7973194240476E-6 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 8.925458132580388E-6 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) count | homozygote | increased large unstained cell number | 8.964578228187747E-6 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | heterozygote | decreased circulating cholesterol level | 8.9956411102321E-6 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote | decreased bone mineral density | 9.073954970517661E-6 | ||
Gemin4 Gemin4em1(IMPC)Ics |
Clinical Chemistry | Total protein | heterozygote | increased circulating total protein level | 9.096852409129497E-6 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 9.141232112597208E-6 | ||
Ankrd27 Ankrd27tm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 9.159306500805542E-6 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 9.20016555028269E-6 | ||
Phf8 Phf8tm1dIcs |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 9.23450988921104E-6 | ||
Sdsl Sdsltm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote | decreased bone mineral density | 9.334871720056981E-6 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Heart Weight | Heart weight | homozygote | increased heart weight | 9.350197615276556E-6 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Combined SHIRPA and Dysmorphology | Activity (body position) | hemizygote | abnormal locomotor behavior | 9.386249985254835E-6 | ||
Diaph2 Diaph2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | hemizygote | increased circulating phosphate level | 9.439117093279492E-6 | ||
Ect2 Ect2tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Tremor | heterozygote | tremors | 9.466431947657838E-6 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Tremor | homozygote | tremors | 9.466431947657838E-6 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | NK Subsets (Q4) | homozygote | increased Ly6C-positive mature NK cell number | 9.518370461591985E-6 | ||
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 9.533554475638084E-6 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Whole arena resting time | homozygote | hyperactivity | 9.54080587689532E-6 | ||
Kcnip3 Kcnip3tm2b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 9.549515198159497E-6 | ||
Trpm6 Trpm6tm1b(KOMP)Wtsi |
Hematology | Mean cell volume | heterozygote | decreased mean corpuscular volume | 9.671048246673308E-6 | ||
Bnc2 Bnc2tm1b(KOMP)Wtsi |
Indirect Calorimetry | Total water intake | heterozygote | decreased fluid intake | 9.684613360150252E-6 | ||
Ptpra Ptpratm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | decreased prepulse inhibition | 9.863021659839433E-6 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 9.88231386145344E-6 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Triglycerides | homozygote | decreased circulating triglyceride level | 9.88283227343345E-6 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Unexpected behaviors | homozygote | abnormal behavior | 1.0014443432737608E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Unexpected behaviors | homozygote | abnormal behavior | 1.0014443432737608E-5 | ||
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Albumin | homozygote | increased circulating serum albumin level | 1.013918881653808E-5 | ||
Gatad2b Gatad2btm1b(EUCOMM)Hmgu |
Hematology | Monocyte differential count | heterozygote | increased monocyte cell number | 1.0219275281997398E-5 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Retinal Blood Vessels Pattern | heterozygote | abnormal retina blood vessel morphology | 1.0332038982596714E-5 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Hematology | Red blood cell count | heterozygote | decreased erythrocyte cell number | 1.0416394616186153E-5 | ||
Cdh13 Cdh13tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 1.042567782860715E-5 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Activity (body position) | homozygote | abnormal locomotor behavior | 1.0430635484226514E-5 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Open Field | Periphery average speed | homozygote | decreased locomotor activity | 1.0469740118423942E-5 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | increased total body fat amount | 1.058428915712284E-5 | ||
Hrh4 Hrh4tm1b(EUCOMM)Hmgu |
Heart Weight | Heart weight | homozygote | decreased heart weight | 1.0656730410119053E-5 | ||
Ahsa2 Ahsa2tm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 1.0739372555690352E-5 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Lower lip morphology | heterozygote | abnormal lip morphology | 1.0764994840428699E-5 | ||
Saxo1 Saxo1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 1.090630394173786E-5 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Rotarod | Latency to fall mean | homozygote | abnormal motor capabilities/coordination/movement | 1.0992743227689061E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 1.0994807780662086E-5 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Fear Conditioning | Context freezing total | homozygote | abnormal contextual conditioning behavior | 1.111294659494888E-5 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | increased lean body mass | 1.1143574738525786E-5 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - abdomen | homozygote | abnormal coat/ hair morphology | 1.117024203267647E-5 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Contact righting | homozygote | impaired righting response | 1.117024203267647E-5 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Gait | homozygote | abnormal gait | 1.117024203267647E-5 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Fear Conditioning | % Context freezing total | homozygote | abnormal contextual conditioning behavior | 1.1199888831470162E-5 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Retinal Blood Vessels | heterozygote | abnormal retina vasculature morphology | 1.125704056903487E-5 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 1.1331846508255694E-5 | ||
Phf8 Phf8tm1dIcs |
Clinical Chemistry | HDL-cholesterol | homozygote | increased circulating HDL cholesterol level | 1.1373213055776432E-5 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Echo | Fractional Shortening | homozygote | increased cardiac muscle contractility | 1.1408652426325716E-5 | ||
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 1.1408977115934249E-5 | ||
Prrt2 Prrt2tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 1.145380792877404E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Open Field | Distance travelled - total | homozygote | decreased locomotor activity | 1.1472881851659622E-5 | ||
Septin3 Septin3tm1b(KOMP)Wtsi |
Fear Conditioning | % Freezing duration habituation-1 | heterozygote | abnormal locomotor behavior | 1.1479242857603822E-5 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Hematology | Platelet count | heterozygote | thrombocytopenia | 1.1552210708032362E-5 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Hematology | Hematocrit | homozygote | decreased hematocrit | 1.159501880465541E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right inner nuclear layer | homozygote | abnormal retina inner nuclear layer morphology | 1.1634436305030249E-5 | ||
Arhgap24 Arhgap24tm1b(KOMP)Wtsi |
Open Field | Center average speed | homozygote | decreased locomotor activity | 1.163934575743042E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote | decreased prepulse inhibition | 1.1642725439742208E-5 | ||
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 1.1678642295009922E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Number of rears - total | homozygote | decreased vertical activity | 1.1680030183924828E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 1.1764404007408302E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total bilirubin | heterozygote | increased circulating bilirubin level | 1.18029793156893E-5 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) count | heterozygote | decreased large unstained cell number | 1.1971235835517291E-5 | ||
Raf1 Raf1tm1b(EUCOMM)Wtsi |
Eye Morphology | Lens Opacity | heterozygote | cataract | 1.1973626897088252E-5 | ||
Raf1 Raf1tm1b(EUCOMM)Wtsi |
Eye Morphology | Lens | heterozygote | abnormal lens morphology | 1.1973626897088252E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 1.197641631733859E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Open Field | Whole arena average speed | homozygote | decreased locomotor activity | 1.2173966752015986E-5 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Hematology | Basophil cell count | homozygote | increased basophil cell number | 1.2448320376279298E-5 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Clinical Chemistry | Creatinine | homozygote | decreased circulating creatinine level | 1.262571822735481E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Distance travelled - total | homozygote | hyperactivity | 1.2629310731426813E-5 | ||
Dync1h1 Dync1h1tm1dIcs |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | heterozygote | impaired glucose tolerance | 1.2810392945539206E-5 | ||
Ncs1 Ncs1tm1b(EUCOMM)Hmgu |
Eye Morphology | Corneal mineralization | homozygote | abnormal cornea morphology | 1.2811648957722355E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Eye Morphology | Corneal mineralization | homozygote | abnormal cornea morphology | 1.2811648957722355E-5 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 1.2835975212510675E-5 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration pre-cue-1 | heterozygote | abnormal freezing behavior | 1.2843146578234155E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Open Field | Periphery average speed | homozygote | hyperactivity | 1.2876476830570027E-5 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Hematology | Large Unstained Cell (LUC) count | homozygote | decreased large unstained cell number | 1.2922527275804896E-5 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 1.3049146218691021E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Hematology | Lymphocyte differential count | heterozygote | decreased lymphocyte cell number | 1.3105845937388949E-5 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 1.3190811841923278E-5 | ||
Pax4 Pax4tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 1.334293483523652E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Periphery resting time | heterozygote | hyperactivity | 1.3370546184887644E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right vitreous humor thickness | homozygote | abnormal vitreous body morphology | 1.3379430129134562E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 1.3385397323872894E-5 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Creatinine | homozygote | increased circulating creatinine level | 1.3534440768125933E-5 | ||
Klf12 Klf12tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Albumin | heterozygote | decreased circulating serum albumin level | 1.357520159217529E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Limb grasp | heterozygote | limb grasping | 1.3620233403344173E-5 | ||
Spn Spnem1(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Activity (body position) | homozygote | abnormal locomotor behavior | 1.3649186257680412E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | NKT Cells (panel B) | heterozygote | increased NK T cell number | 1.3758376553596463E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 1.378975957777584E-5 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Eye Morphology | Vitreous | heterozygote | abnormal vitreous body morphology | 1.3831089745508507E-5 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 1.3846213732904289E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Open Field | Whole arena average speed | homozygote | hyperactivity | 1.397236883349251E-5 | ||
Cav1 Cav1em2(IMPC)Ics |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 1.4016714885656256E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Electrocardiogram (ECG) | ST | homozygote | shortened ST segment | 1.4063307389733382E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 1.418736337654991E-5 | ||
Ttc39a Ttc39atm1b(KOMP)Mbp |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 1.4313470273918938E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Clinical Chemistry | HDL-cholesterol | homozygote | decreased circulating HDL cholesterol level | 1.4333223589346744E-5 | ||
Kif5c Kif5ctm1dIcs |
Hematology | Lymphocyte differential count | heterozygote | decreased lymphocyte cell number | 1.4341908354253974E-5 | ||
Dpp4 Dpp4tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.4361814464791678E-5 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Immunophenotyping | NKT Cells (panel B) | homozygote | decreased NK T cell number | 1.4404467037820723E-5 | ||
Cfap119 Cfap119tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | decreased locomotor activity | 1.44508812809363E-5 | ||
Gemin4 Gemin4em1(IMPC)Ics |
Clinical Chemistry | HDL-cholesterol | heterozygote | increased circulating HDL cholesterol level | 1.446285386919044E-5 | ||
Tti2 Tti2tm1b(KOMP)Wtsi |
Hematology | Lymphocyte differential count | heterozygote | decreased lymphocyte cell number | 1.459356371924514E-5 | ||
Taf2 Taf2tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | heterozygote | long tibia | 1.466502362745814E-5 | ||
Klf12 Klf12tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Calcium | heterozygote | decreased circulating calcium level | 1.4697864571644459E-5 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 1.4713564269186463E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 1.474746113672154E-5 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Hematology | Eosinophil differential count | homozygote | increased eosinophil cell number | 1.4789125089009758E-5 | ||
Bace2 Bace2tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 1.4890239981468767E-5 | ||
Scaper Scapertm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 1.4894079868099652E-5 | ||
Cdh9 Cdh9tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 1.4903318515280262E-5 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Open Field | Periphery distance travelled | heterozygote | decreased locomotor activity | 1.4987531358201522E-5 | ||
Phf8 Phf8tm1dIcs |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 1.511535174358869E-5 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 1.5465089745703153E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | Glucose | homozygote | increased circulating glucose level | 1.5732601241325028E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 1.589205021446105E-5 | ||
Ackr3 Ackr3tm2b(EUCOMM)Wtsi |
Hematology | Mean cell hemoglobin concentration | heterozygote | increased mean corpuscular hemoglobin concentration | 1.596968104422558E-5 | ||
Casq1 Casq1tm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration pre-cue-2 | homozygote | abnormal freezing behavior | 1.5981964679667726E-5 | ||
Satb1 Satb1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 1.600015275471378E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Open Field | Distance travelled - total | heterozygote | hyperactivity | 1.6068499462562613E-5 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Vocalization | heterozygote | abnormal vocalization | 1.6107247574836947E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote | increased exploration in new environment | 1.6128087736433372E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | HDL-cholesterol | homozygote | decreased circulating HDL cholesterol level | 1.613739732420072E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Hemoglobin | homozygote | decreased hemoglobin content | 1.633769898035098E-5 | ||
Krt8 Krt8tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | heterozygote | decreased exploration in new environment | 1.6420821339124814E-5 | ||
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 1.6446696463390253E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Startle response | homozygote | abnormal startle reflex | 1.65947694767965E-5 | ||
Gatad2b Gatad2btm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | heterozygote | increased mean corpuscular volume | 1.6742260413593613E-5 | ||
Cdc27 Cdc27tm1dIcs |
Combined SHIRPA and Dysmorphology | Locomotor activity | heterozygote | decreased exploration in new environment | 1.695775608823169E-5 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.697980405879207E-5 | ||
Padi3 Padi3tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | increased total body fat amount | 1.706852162897121E-5 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 1.7172162188217044E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Calcium | heterozygote | increased circulating calcium level | 1.7195565305883065E-5 | ||
Lmna Lmnatm1b(EUCOMM)Wtsi |
Eye Morphology | Corneal ulcer | heterozygote | cornea ulcer | 1.7295706129516475E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Limb grasp | heterozygote | limb grasping | 1.7313295757048763E-5 | ||
Rcan1 Rcan1tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | increased lean body mass | 1.7506827134639025E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Whole arena resting time | heterozygote | hyperactivity | 1.7523805581731722E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - abdomen | homozygote | abnormal coat/ hair morphology | 1.7612108422326855E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Hematology | Neutrophil differential count | homozygote | increased neutrophil cell number | 1.7706724975141697E-5 | ||
Bmp10 Bmp10tm3b(EUCOMM)Hmgu |
Clinical Chemistry | Creatinine | heterozygote | decreased circulating creatinine level | 1.770684502844233E-5 | ||
Padi3 Padi3tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | increased total body fat amount | 1.7756503439159133E-5 | ||
Gpr108 Gpr108tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.8078917491948232E-5 | ||
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 1.8190345144830644E-5 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 1.8282247765455395E-5 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Eye Morphology | Optic Disc | homozygote | abnormal optic disk morphology | 1.8346136130276136E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Eye Morphology | Left corneal thickness | homozygote | increased cornea thickness | 1.8356902728555724E-5 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 1.839813921833411E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | ST | homozygote | prolonged ST segment | 1.8479040591046214E-5 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 1.8515303963795304E-5 | ||
Nrp1 Nrp1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | heterozygote | decreased prepulse inhibition | 1.8766659195534885E-5 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Calcium | homozygote | decreased circulating calcium level | 1.882804099295754E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | CD8 CD44+CD62L+ T cells | heterozygote | decreased effector memory CD8-positive, alpha-beta T cell number | 1.90593782463111E-5 | ||
Dnm1l Dnm1ltm1b(KOMP)Wtsi |
Eye Morphology | Corneal mineralization | heterozygote | abnormal cornea morphology | 1.920969589264132E-5 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Distance travelled - total | homozygote | decreased locomotor activity | 1.927881021401845E-5 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 1.9397006326471455E-5 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Eye Morphology | Right outer nuclear layer | heterozygote | abnormal retina outer nuclear layer morphology | 1.9410363165661693E-5 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | homozygote | decreased prepulse inhibition | 1.943623647093773E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Hematology | Lymphocyte cell count | heterozygote | decreased lymphocyte cell number | 1.9448903913144022E-5 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Open Field | Center distance travelled | heterozygote | decreased locomotor activity | 1.955591687874403E-5 | ||
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu |
Open Field | Percentage center time | heterozygote | abnormal behavior | 1.9663586499518715E-5 | ||
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu |
Open Field | Center permanence time | heterozygote | decreased thigmotaxis | 1.9663586499518715E-5 | ||
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu |
Open Field | Periphery permanence time | heterozygote | decreased thigmotaxis | 1.9663586499518715E-5 | ||
Dnm1l Dnm1ltm1b(KOMP)Wtsi |
Eye Morphology | Persistence of hyaloid vascular system | heterozygote | persistence of hyaloid vascular system | 1.9677985619637184E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | cDCs CD11b Type | homozygote | increased CD11b-high dendritic cell number | 1.9738412447622977E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Hematology | White blood cell count | heterozygote | decreased leukocyte cell number | 1.9783918105531484E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | increased startle reflex | 1.9797322238446213E-5 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Open Field | Number of center entries | heterozygote | decreased locomotor activity | 2.00394460989628E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration context-2 | heterozygote | abnormal contextual conditioning behavior | 2.0107378077227622E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Open Field | Periphery distance travelled | homozygote | decreased locomotor activity | 2.0241448510205373E-5 | ||
Lca5l Lca5lem1(IMPC)Ics |
Eye Morphology | Left total retinal thickness | homozygote | increased total retina thickness | 2.0287658117013052E-5 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 2.0408395357662812E-5 | ||
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi |
Clinical Chemistry | Cholesterol ratio | homozygote | abnormal cholesterol homeostasis | 2.0471268726396374E-5 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Hematology | White blood cell count | heterozygote | decreased leukocyte cell number | 2.051218325505033E-5 | ||
Dbn1 Dbn1tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 2.0568162653944455E-5 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Percentage center movement time | homozygote | decreased anxiety-related response | 2.0605173631338403E-5 | ||
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi |
Eye Morphology | Left inner nuclear layer | heterozygote | abnormal retina inner nuclear layer morphology | 2.0616595065803267E-5 | ||
Lca5l Lca5lem1(IMPC)Ics |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 2.0688519725808874E-5 | ||
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 2.0697778381872922E-5 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Clinical Chemistry | HDL-cholesterol | homozygote | decreased circulating HDL cholesterol level | 2.0819228666368872E-5 | ||
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI3 | homozygote | increased prepulse inhibition | 2.087506072712131E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Echo | Fractional Shortening | homozygote | decreased cardiac muscle contractility | 2.090742054861039E-5 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Hematology | Mean cell volume | heterozygote | increased mean corpuscular volume | 2.091642454615794E-5 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 2.092267641273793E-5 | ||
Ptpra Ptpratm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 2.105966632370837E-5 | ||
Slx1b Slx1bem1(IMPC)Ics |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 2.1089494111947715E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | increased lean body mass | 2.1089836081955582E-5 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Indirect Calorimetry | Total water intake | heterozygote | increased fluid intake | 2.120043063769117E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Rotarod | Latency to fall mean | homozygote | abnormal motor capabilities/coordination/movement | 2.122455225617159E-5 | ||
Pnpla1 Pnpla1tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Body length | heterozygote | increased body length | 2.12670838664053E-5 | ||
Hmgn1 Hmgn1em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | increased total body fat amount | 2.1376761651481502E-5 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI2 | heterozygote | increased prepulse inhibition | 2.140497963409871E-5 | ||
Tm7sf2 Tm7sf2tm1b(KOMP)Wtsi |
Open Field | Number of rears - total | homozygote | increased vertical activity | 2.153016612282954E-5 | ||
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi |
Eye Morphology | Left vitreous humour thickness | homozygote | abnormal vitreous body morphology | 2.158994902856648E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 2.1604686480714008E-5 | ||
Gp6 Gp6tm2b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Vibrissae - appearance | homozygote | abnormal vibrissa morphology | 2.161036172765307E-5 | ||
Ackr3 Ackr3tm2b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 2.1612528144032694E-5 | ||
Epx Epxtm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | increased total body fat amount | 2.172873428207822E-5 | ||
Spn Spnem1(IMPC)Ics |
Fear Conditioning | % Freezing duration pre-cue-2 | homozygote | abnormal freezing behavior | 2.186751225963235E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 2.2079066184232943E-5 | ||
Wdr4 Wdr4em1(IMPC)Ics |
X-ray | Tibia length | heterozygote | long tibia | 2.2152969904709607E-5 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | hyperactivity | 2.2182997781783342E-5 | ||
Cx3cl1 Cx3cl1em3(IMPC)Ics |
Open Field | Periphery average speed | homozygote | decreased locomotor activity | 2.2266607629717328E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Whole arena resting time | hemizygote | hyperactivity | 2.25307830987731E-5 | ||
4933430I17Rik 4933430I17Riktm1b(EUCOMM)Wtsi |
Echo | Fractional Shortening | homozygote | increased cardiac muscle contractility | 2.2605288904742338E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Echo | HR | homozygote | increased heart rate | 2.26402044063434E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Hematology | Neutrophil differential count | heterozygote | increased neutrophil cell number | 2.279328509757761E-5 | ||
Trmt1 Trmt1tm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | heterozygote | increased mean corpuscular volume | 2.2870282919029705E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 2.2968795747146942E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | heterozygote | short tibia | 2.3021559172775596E-5 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Clinical Chemistry | Glucose | heterozygote | decreased circulating glucose level | 2.3142183636082336E-5 | ||
Lmna Lmnatm1b(EUCOMM)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 2.3300115572055802E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Open Field | Number of rears - total | homozygote | increased vertical activity | 2.333840893697925E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Number of center entries | hemizygote | hyperactivity | 2.3547625460196286E-5 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Immunophenotyping | NK Cells (panel B) | homozygote | increased NK cell number | 2.3610671632923186E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | homozygote | decreased lymphocyte cell number | 2.368184141232632E-5 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Rotarod | Latency to fall mean | homozygote | abnormal motor capabilities/coordination/movement | 2.3826887627365068E-5 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Eye Morphology | Persistence of hyaloid vascular system | homozygote | persistence of hyaloid vascular system | 2.3872731617302634E-5 | ||
Ppp4c Ppp4cem1(IMPC)Ics |
Clinical Chemistry | Total bilirubin | heterozygote | increased circulating bilirubin level | 2.4005099476198666E-5 | ||
Dusp11 Dusp11tm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 2.412226422165986E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 2.4408038370893337E-5 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Heart Weight | Tibia length | heterozygote | short tibia | 2.442972981953062E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 2.4477414626744576E-5 | ||
Bmp10 Bmp10tm3b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | heterozygote | improved glucose tolerance | 2.4488972485414706E-5 | ||
Dync1h1 Dync1h1tm1dIcs |
Combined SHIRPA and Dysmorphology | Vocalization | heterozygote | abnormal vocalization | 2.451576256135013E-5 | ||
Setbp1 Setbp1tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Vocalization | heterozygote | abnormal vocalization | 2.451576256135013E-5 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Vocalization | heterozygote | abnormal vocalization | 2.451576256135013E-5 | ||
App Apptm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | decreased grip strength | 2.4608190869912505E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Eye Morphology | Cornea | heterozygote | abnormal cornea morphology | 2.4881126591935754E-5 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 2.4986988137243316E-5 | ||
Sh2b1 Sh2b1em1(IMPC)Ics |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | heterozygote | impaired glucose tolerance | 2.501402013876941E-5 | ||
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 2.5059720428544097E-5 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 2.5109013222390786E-5 | ||
Cx3cl1 Cx3cl1em3(IMPC)Ics |
Open Field | Number of rears - total | homozygote | decreased vertical activity | 2.5169749278575182E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 2.5185985577991232E-5 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 2.5194836780428886E-5 | ||
Nfatc2ip Nfatc2ipem1(IMPC)Ics |
Fear Conditioning | % Freezing duration habituation-2 | homozygote | abnormal locomotor behavior | 2.5218012524419464E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 2.525192940083798E-5 | ||
Nlk Nlktm2b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | increased startle reflex | 2.5331486540380865E-5 | ||
Phf8 Phf8tm1dIcs |
Eye Morphology | Left anterior chamber depth | hemizygote | abnormal eye anterior chamber depth | 2.533893712097779E-5 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 2.5350831492687576E-5 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Clinical Chemistry | Glucose | homozygote | increased circulating glucose level | 2.540397508710157E-5 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | heterozygote | decreased lymphocyte cell number | 2.5480925614829175E-5 | ||
Ackr3 Ackr3tm2b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 2.554289676481858E-5 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | decreased total body fat amount | 2.5895415092236362E-5 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | homozygote | increased blood urea nitrogen level | 2.6341882403357886E-5 | ||
Spn Spnem1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Body length | homozygote | increased body length | 2.6448948119650595E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Fear Conditioning | Context freezing total | homozygote | abnormal contextual conditioning behavior | 2.651647992024664E-5 | ||
Gp6 Gp6tm2b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | long tibia | 2.7157115255249664E-5 | ||
Slx9 Slx9tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 2.7216181479161605E-5 | ||
Ackr3 Ackr3tm2b(EUCOMM)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | heterozygote | decreased grip strength | 2.723376383073628E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration context-2 | homozygote | abnormal contextual conditioning behavior | 2.7247888283454813E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Context freezing total | homozygote | abnormal contextual conditioning behavior | 2.7421301638241857E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 2.7552365281735547E-5 | ||
Taok2 Taok2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 2.7575853891903535E-5 | ||
Stradb Stradbtm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 2.803242750815116E-5 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | heterozygote | decreased lymphocyte cell number | 2.804354517138563E-5 | ||
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Body length | homozygote | increased body length | 2.8124086384195834E-5 | ||
Coq6 Coq6tm1b(EUCOMM)Hmgu |
Eye Morphology | Vitreous | heterozygote | abnormal vitreous body morphology | 2.815172410919331E-5 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 2.843182664946653E-5 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Hematology | Red blood cell count | heterozygote | decreased erythrocyte cell number | 2.8440841560950503E-5 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 2.8754653612850234E-5 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | heterozygote | decreased blood urea nitrogen level | 2.880163629015442E-5 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 2.884527202695608E-5 | ||
Trpm6 Trpm6tm1b(KOMP)Wtsi |
Eye Morphology | Right anterior chamber depth | heterozygote | abnormal eye anterior chamber depth | 2.8872324037365615E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Percentage center movement time | homozygote | increased anxiety-related response | 2.8979502531001344E-5 | ||
Ncam2 Ncam2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 2.9014818210271187E-5 | ||
Trpm6 Trpm6tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | heterozygote | increased grip strength | 2.9047268981230445E-5 | ||
Slc37a1 Slc37a1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | increased total body fat amount | 2.9261422241688706E-5 | ||
Fut4 Fut4em1(IMPC)Ics |
Clinical Chemistry | Creatinine | homozygote | decreased circulating creatinine level | 2.988352753163781E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Hematology | Platelet count | heterozygote | thrombocytosis | 2.9917766369180754E-5 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Eye Morphology | Corneal mineralization | homozygote | abnormal cornea morphology | 3.0092325687292032E-5 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - back | homozygote | abnormal coat/ hair morphology | 3.0192453777999617E-5 | ||
Il2rb Il2rbtm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - abdomen | homozygote | abnormal coat/ hair morphology | 3.0192453777999617E-5 | ||
Bace2 Bace2tm1b(EUCOMM)Wtsi |
Eye Morphology | Left corneal thickness | homozygote | increased cornea thickness | 3.020923577423673E-5 | ||
Cdh9 Cdh9tm1b(KOMP)Wtsi |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 3.022550663445145E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 3.0516564947902225E-5 | ||
Zc3h12d Zc3h12dtm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 3.05534886138048E-5 | ||
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 3.0847160815028474E-5 | ||
Setbp1 Setbp1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total cholesterol | heterozygote | decreased circulating cholesterol level | 3.107878001173958E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Hematology | White blood cell count | heterozygote | decreased leukocyte cell number | 3.112374179181643E-5 | ||
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Glucose | homozygote | increased circulating glucose level | 3.1304527510656044E-5 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 3.130564800812863E-5 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Eye Morphology | Retinal Blood Vessels Structure | homozygote | abnormal retina blood vessel morphology | 3.1342064175987616E-5 | ||
App Apptm1b(KOMP)Wtsi |
Clinical Chemistry | Calcium | heterozygote | increased circulating calcium level | 3.1717412639409304E-5 | ||
Padi3 Padi3tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | decreased lean body mass | 3.210710201528855E-5 | ||
Nae1 Nae1tm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | heterozygote | increased fasting circulating glucose level | 3.2122363336384296E-5 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | homozygote | decreased lymphocyte cell number | 3.2165520678972825E-5 | ||
4933430I17Rik 4933430I17Riktm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 3.2391257263952866E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Eye Morphology | Right inner nuclear layer | heterozygote | abnormal retina inner nuclear layer morphology | 3.2414602173957974E-5 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Retina (combined) | heterozygote | abnormal retina morphology | 3.247526547056623E-5 | ||
Spn Spnem1(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Unexpected behaviors | homozygote | abnormal behavior | 3.278563963249326E-5 | ||
Satb1 Satb1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Aspartate aminotransferase | heterozygote | increased circulating aspartate transaminase level | 3.280003511463292E-5 | ||
Taf2 Taf2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | heterozygote | increased circulating cholesterol level | 3.32303716277238E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Fear Conditioning | % Freezing duration pre-cue-2 | homozygote | abnormal freezing behavior | 3.329063838464208E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | homozygote | decreased blood urea nitrogen level | 3.3341344533255324E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Fear Conditioning | % Cue freezing total | homozygote | abnormal cued conditioning behavior | 3.3347758289892226E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
X-ray | Tibia length | homozygote | short tibia | 3.3361844543833286E-5 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 3.356707384227775E-5 | ||
Gemin4 Gemin4em1(IMPC)Ics |
Clinical Chemistry | Total cholesterol | heterozygote | increased circulating cholesterol level | 3.373439176357351E-5 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | homozygote | decreased blood urea nitrogen level | 3.37474157277029E-5 | ||
Tmem50b Tmem50btm1b(EUCOMM)Wtsi |
Eye Morphology | Right corneal thickness | homozygote | increased cornea thickness | 3.377728717168793E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Fear Conditioning | Context freezing total | homozygote | abnormal contextual conditioning behavior | 3.388512413948774E-5 | ||
Cav1 Cav1em2(IMPC)Ics |
Echo | Fractional Shortening | homozygote | decreased cardiac muscle contractility | 3.399742126930505E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Echo | LVIDd | homozygote | abnormal heart left ventricle morphology | 3.408040356589481E-5 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
X-ray | Digit integrity | heterozygote | abnormal digit morphology | 3.414812817936763E-5 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 3.4415155823808163E-5 | ||
Cidea Cideatm1b(EUCOMM)Hmgu |
Eye Morphology | Cornea | homozygote | abnormal cornea morphology | 3.443966124905273E-5 | ||
Cidea Cideatm1b(EUCOMM)Hmgu |
Eye Morphology | Corneal opacity | homozygote | corneal opacity | 3.443966124905273E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Immunophenotyping | Others | homozygote | immune system phenotype | 3.450748044997454E-5 | ||
Dgkk Dgkkem1(IMPC)Ics |
Clinical Chemistry | Alkaline phosphatase | hemizygote | increased circulating alkaline phosphatase level | 3.451268275966868E-5 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Hematology | Hematocrit | heterozygote | decreased hematocrit | 3.453335739322938E-5 | ||
Sdsl Sdsltm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Area | homozygote | abnormal bone structure | 3.5000124626094475E-5 | ||
Tiam1 Tiam1tm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 3.500021921354346E-5 | ||
Mtmr12 Mtmr12tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 3.504618871374987E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration context-1 | homozygote | abnormal contextual conditioning behavior | 3.521352482493967E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 3.526182263158262E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Open Field | Periphery average speed | homozygote | hyperactivity | 3.5380500776227564E-5 | ||
Rbfox1 Rbfox1tm1b(KOMP)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 3.549591565388255E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Context freezing total | homozygote | abnormal contextual conditioning behavior | 3.574429501895793E-5 | ||
Rcan1 Rcan1tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | decreased total body fat amount | 3.5845059755956754E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 3.5860870411852375E-5 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Immunophenotyping | NK cells (panel A) | homozygote | increased NK cell number | 3.587094761314802E-5 | ||
Cfap119 Cfap119tm1b(EUCOMM)Hmgu |
Open Field | Distance travelled - total | homozygote | decreased locomotor activity | 3.588647086871788E-5 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 3.6223143979441375E-5 | ||
Maz Mazem1(IMPC)Ics |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 3.660851143649779E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration context-3 | homozygote | abnormal contextual conditioning behavior | 3.6643603380071E-5 | ||
Arhgap24 Arhgap24tm1b(KOMP)Wtsi |
Open Field | Whole arena average speed | homozygote | decreased locomotor activity | 3.6654753785114735E-5 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Open Field | Periphery distance travelled | homozygote | decreased locomotor activity | 3.679681685753167E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration pre-cue-2 | homozygote | abnormal freezing behavior | 3.680581721710041E-5 | ||
Krt8 Krt8tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | heterozygote | increased prepulse inhibition | 3.7072255508974195E-5 | ||
Cdh13 Cdh13tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 3.71381247532554E-5 | ||
Csf2rb Csf2rbtm2b(EUCOMM)Hmgu |
Open Field | Percentage center movement time | heterozygote | decreased anxiety-related response | 3.736685903277248E-5 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Creatinine | homozygote | decreased circulating creatinine level | 3.7485326174646616E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QT | homozygote | prolonged QT interval | 3.757956437766552E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Open Field | Percentage center movement time | homozygote | increased anxiety-related response | 3.766411464312114E-5 | ||
Nol8 Nol8tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | heterozygote | increased fasting circulating glucose level | 3.7785623135278E-5 | ||
Cdh13 Cdh13tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QT | homozygote | shortened QT interval | 3.793064024648629E-5 | ||
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 3.8155158108565956E-5 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Indirect Calorimetry | Respiratory Exchange Ratio | homozygote | decreased respiratory quotient | 3.817743345280178E-5 | ||
Dusp11 Dusp11tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Aspartate aminotransferase | homozygote | increased circulating aspartate transaminase level | 3.834109884337522E-5 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Clinical Chemistry | Total bilirubin | homozygote | increased circulating bilirubin level | 3.857468982459977E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 3.8610363844782114E-5 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | heterozygote | short tibia | 3.8777972804382443E-5 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 3.888334322255105E-5 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 3.8938323996262625E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Open Field | Center distance travelled | heterozygote | hyperactivity | 3.893909524776973E-5 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Echo | LVPWd | heterozygote | thick ventricular wall | 3.897841088473797E-5 | ||
Il10ra Il10ratm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | decreased startle reflex | 3.900188676198013E-5 | ||
Gatad2b Gatad2btm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 3.929771628463641E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Heart Weight | Heart weight | homozygote | increased heart weight | 3.9507394831161946E-5 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Eye Morphology | Corneal opacity | homozygote | corneal opacity | 3.9754773752065375E-5 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 3.979641405749135E-5 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 3.982842463301495E-5 | ||
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 3.9882739656604826E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Hematology | White blood cell count | homozygote | increased leukocyte cell number | 3.997231033281423E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Open Field | Whole arena resting time | heterozygote | hyperactivity | 3.999221007688902E-5 | ||
Fut4 Fut4em1(IMPC)Ics |
Fear Conditioning | % Freezing duration pre-cue-2 | homozygote | abnormal freezing behavior | 4.0018650906858966E-5 | ||
Rwdd3 Rwdd3tm1b(KOMP)Wtsi |
Electrocardiogram (ECG) | ST | heterozygote | prolonged ST segment | 4.0126466046785936E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 4.0144856029655784E-5 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 4.0181708754971623E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Fear Conditioning | Context freezing total | homozygote | abnormal contextual conditioning behavior | 4.081851875525899E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration context-3 | heterozygote | abnormal contextual conditioning behavior | 4.083125168108381E-5 | ||
Gemin4 Gemin4em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Fat mass | heterozygote | increased total body fat amount | 4.089831418241374E-5 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Eye Morphology | Retina (combined) | heterozygote | abnormal retina morphology | 4.113533577765338E-5 | ||
Cdc27 Cdc27tm1dIcs |
Body Composition (DEXA lean/fat) | Fat/Body weight | heterozygote | increased total body fat amount | 4.121931124245748E-5 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QT | heterozygote | prolonged QT interval | 4.124428232898936E-5 | ||
Cebpz Cebpztm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Fat/Body weight | heterozygote | increased total body fat amount | 4.1449846321484074E-5 | ||
Gemin4 Gemin4em1(IMPC)Ics |
Rotarod | Latency to fall mean | heterozygote | abnormal motor capabilities/coordination/movement | 4.1676270484458655E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Periphery resting time | homozygote | hyperactivity | 4.168168379692361E-5 | ||
Smc5 Smc5tm1b(KOMP)Wtsi |
Hematology | Red blood cell count | heterozygote | decreased erythrocyte cell number | 4.171723412582651E-5 | ||
Ncam2 Ncam2tm1b(EUCOMM)Hmgu |
Echo | Fractional Shortening | homozygote | decreased cardiac muscle contractility | 4.1721901652636006E-5 | ||
Sh3tc1 Sh3tc1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 4.194873326923698E-5 | ||
Coq6 Coq6tm1b(EUCOMM)Hmgu |
Eye Morphology | Corneal mineralization | heterozygote | abnormal cornea morphology | 4.199800605420023E-5 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 4.2156854760833085E-5 | ||
Cav1 Cav1em2(IMPC)Ics |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 4.23461569880601E-5 | ||
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Cholesterol ratio | homozygote | abnormal cholesterol homeostasis | 4.2569226934574544E-5 | ||
Olig1 Olig1em2(IMPC)Ics |
Clinical Chemistry | Phosphorus | homozygote | decreased circulating phosphate level | 4.2665720684453845E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | increased lean body mass | 4.284303213353269E-5 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Hematology | Hematocrit | heterozygote | decreased hematocrit | 4.30039617640432E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Locomotor activity | heterozygote | decreased exploration in new environment | 4.3062893382739276E-5 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Clinical Chemistry | Glucose | homozygote | decreased circulating glucose level | 4.306802657083608E-5 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Eye Morphology | Retinal Blood Vessels | homozygote | abnormal retina vasculature morphology | 4.315025944379158E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Fear Conditioning | % Context freezing total | homozygote | abnormal contextual conditioning behavior | 4.355964483693242E-5 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Eye Morphology | Vitreous | homozygote | abnormal vitreous body morphology | 4.3638021452352405E-5 | ||
Bnc2 Bnc2tm1b(KOMP)Wtsi |
Eye Morphology | Right corneal thickness | heterozygote | increased cornea thickness | 4.366265420685522E-5 | ||
Plscr1 Plscr1tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QRS | homozygote | shortened QRS complex duration | 4.372711919131689E-5 | ||
Gpr101 Gpr101tm1b(KOMP)Mbp |
Open Field | Center resting time | hemizygote | decreased locomotor activity | 4.3916872527915984E-5 | ||
Kctd15 Kctd15tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | heterozygote | increased blood urea nitrogen level | 4.4063577661290765E-5 | ||
Ino80 Ino80tm1a(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QRS | heterozygote | prolonged QRS complex duration | 4.415403964230791E-5 | ||
Mmp11 Mmp11tm1b(EUCOMM)Hmgu |
Hematology | Mean corpuscular hemoglobin | homozygote | decreased mean corpuscular hemoglobin | 4.4194897782290354E-5 | ||
Cd276 Cd276tm2b(EUCOMM)Hmgu |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 4.4339452870190144E-5 | ||
Mapt Mapttm1b(EUCOMM)Hmgu |
Indirect Calorimetry | Total water intake | homozygote | increased fluid intake | 4.454005102161318E-5 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Clinical Chemistry | HDL-cholesterol | heterozygote | increased circulating HDL cholesterol level | 4.4631622586166486E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Periphery permanence time | homozygote | increased thigmotaxis | 4.470697240321897E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Percentage center time | homozygote | abnormal behavior | 4.470697240321897E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Center permanence time | homozygote | increased thigmotaxis | 4.470697240321897E-5 | ||
Gorasp1 Gorasp1tm1b(KOMP)Wtsi |
Clinical Chemistry | Creatinine | heterozygote | decreased circulating creatinine level | 4.4773325498681515E-5 | ||
Capn10 Capn10tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 4.480769712245092E-5 | ||
Nfatc2ip Nfatc2ipem1(IMPC)Ics |
Hematology | Eosinophil differential count | homozygote | increased eosinophil cell number | 4.488696140469983E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 4.489393177209422E-5 | ||
Arhgap24 Arhgap24tm1b(KOMP)Wtsi |
Open Field | Periphery average speed | homozygote | decreased locomotor activity | 4.505982724367641E-5 | ||
Dyrk2 Dyrk2em1(IMPC)Ics |
Hematology | Large Unstained Cell (LUC) differential count | heterozygote | decreased large unstained cell number | 4.506540426518768E-5 | ||
Pik3ap1 Pik3ap1tm1b(KOMP)Wtsi |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 4.517448542173952E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Eye Morphology | Retina (combined) | homozygote | abnormal retina morphology | 4.5248867536429316E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | NK Cells (panel B) | heterozygote | increased NK cell number | 4.525945769273676E-5 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 4.5585897169075906E-5 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | heterozygote | increased total body fat amount | 4.586187787936069E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Fear Conditioning | % Context freezing total | heterozygote | abnormal contextual conditioning behavior | 4.610780524672009E-5 | ||
Dusp11 Dusp11tm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 4.618667662725784E-5 | ||
Carmil2 Carmil2tm1b(KOMP)Mbp |
Clinical Chemistry | Cholesterol ratio | homozygote | abnormal cholesterol homeostasis | 4.6235392801463604E-5 | ||
Tiam1 Tiam1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | decreased locomotor activity | 4.647257082979195E-5 | ||
Phf8 Phf8tm1dIcs |
Echo | LVIDd | homozygote | abnormal heart left ventricle morphology | 4.647698006010614E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 4.662766514229588E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Right inner nuclear layer | homozygote | abnormal retina inner nuclear layer morphology | 4.6986468078102916E-5 | ||
Trpm6 Trpm6tm1b(KOMP)Wtsi |
Clinical Chemistry | Phosphorus | heterozygote | decreased circulating phosphate level | 4.7057172196218744E-5 | ||
Stat1 Stat1tm2b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote | decreased bone mineral content | 4.7091434680623934E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Heart Weight | Tibia length | heterozygote | short tibia | 4.726017141365446E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
X-ray | Tibia length | homozygote | short tibia | 4.767148493556306E-5 | ||
Ptpra Ptpratm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 4.767163409269415E-5 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Glucose | heterozygote | increased circulating glucose level | 4.782039832207374E-5 | ||
D16Ertd472e D16Ertd472etm1b(EUCOMM)Wtsi |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 4.782497126143426E-5 | ||
Baiap2l2 Baiap2l2tm1a(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 4.789915692526847E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Albumin | homozygote | decreased circulating serum albumin level | 4.8121826694114134E-5 | ||
Taf2 Taf2tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength normalised against body weight | heterozygote | decreased grip strength | 4.8132471420103684E-5 | ||
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 4.850427285418846E-5 | ||
Nlk Nlktm2b(KOMP)Wtsi |
Clinical Chemistry | Alkaline phosphatase | heterozygote | increased circulating alkaline phosphatase level | 4.877387618762441E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 4.951441951561719E-5 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Hematology | White blood cell count | heterozygote | decreased leukocyte cell number | 4.9642669182503596E-5 | ||
Tmem63b Tmem63btm1b(EUCOMM)Wtsi |
Open Field | Periphery resting time | heterozygote | hyperactivity | 4.974851617589593E-5 | ||
Lcp2 Lcp2tm1b(KOMP)Wtsi |
Eye Morphology | Lens Opacity | heterozygote | cataract | 4.979671575711109E-5 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Heart Weight | Tibia length | heterozygote | short tibia | 4.9843638407764956E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alanine aminotransferase | homozygote | increased circulating alanine transaminase level | 5.014327325625345E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Clinical Chemistry | Creatinine | homozygote | increased circulating creatinine level | 5.015170609112829E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 5.029118256061338E-5 | ||
Cidea Cideatm1b(EUCOMM)Hmgu |
Eye Morphology | Right outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 5.076361776445992E-5 | ||
Ttc39a Ttc39atm1b(KOMP)Mbp |
Hematology | Mean cell hemoglobin concentration | homozygote | decreased mean corpuscular hemoglobin concentration | 5.0981310778297484E-5 | ||
Ect2 Ect2tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 5.1078703108942136E-5 | ||
Gp6 Gp6tm2b(EUCOMM)Hmgu |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 5.1108527259202674E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Fear Conditioning | Context freezing total | heterozygote | abnormal contextual conditioning behavior | 5.110908023198135E-5 | ||
Pax4 Pax4tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | heterozygote | increased circulating total protein level | 5.130821227794513E-5 | ||
Cx3cl1 Cx3cl1em3(IMPC)Ics |
Open Field | Distance travelled - total | homozygote | decreased locomotor activity | 5.136207983014174E-5 | ||
Padi3 Padi3tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | decreased lean body mass | 5.137575135449879E-5 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | decreased grip strength | 5.1467774028424174E-5 | ||
Ttc39a Ttc39atm1b(KOMP)Mbp |
Heart Weight | Heart weight | homozygote | increased heart weight | 5.157957275514491E-5 | ||
Cidea Cideatm1b(EUCOMM)Hmgu |
Clinical Chemistry | Alkaline phosphatase | homozygote | increased circulating alkaline phosphatase level | 5.169043652131222E-5 | ||
Ahsa2 Ahsa2tm1b(EUCOMM)Wtsi |
Eye Morphology | Corneal mineralization | homozygote | abnormal cornea morphology | 5.171763768885285E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Immunophenotyping | CD24+ CD4 T cells | homozygote | immune system phenotype | 5.1778231863863766E-5 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Eye Morphology | Persistence of hyaloid vascular system | homozygote | persistence of hyaloid vascular system | 5.184971814742312E-5 | ||
Gpr108 Gpr108tm1b(EUCOMM)Hmgu |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 5.187550050322898E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 5.197489736019634E-5 | ||
Tmem50b Tmem50btm1b(EUCOMM)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | homozygote | decreased grip strength | 5.198881990509108E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Gait | homozygote | abnormal gait | 5.202514148550108E-5 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Head bobbing | homozygote | head bobbing | 5.202514148550108E-5 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Fat/Body weight | homozygote | increased total body fat amount | 5.2333856729092076E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Clinical Chemistry | Total protein | heterozygote | increased circulating total protein level | 5.279888864606619E-5 | ||
Maz Mazem1(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Head morphology | heterozygote | abnormal head morphology | 5.284534563543275E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Retinal Blood Vessels | homozygote | abnormal retina vasculature morphology | 5.341996075003408E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Retinal Blood Vessels Pattern | homozygote | abnormal retina blood vessel morphology | 5.341996075003408E-5 | ||
Krt8 Krt8tm1b(EUCOMM)Hmgu |
Hematology | Neutrophil differential count | heterozygote | increased neutrophil cell number | 5.3791558457305655E-5 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration pre-cue-1 | heterozygote | abnormal freezing behavior | 5.390495789470151E-5 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Hematology | Lymphocyte cell count | homozygote | increased lymphocyte cell number | 5.397247150540352E-5 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Immunophenotyping | Monocytes | homozygote | increased monocyte cell number | 5.398517896537669E-5 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Fear Conditioning | Context freezing total | homozygote | abnormal contextual conditioning behavior | 5.4062529670773074E-5 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 5.4412666941061616E-5 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Whole arena resting time | homozygote | decreased locomotor activity | 5.4696822189725935E-5 | ||
Saxo1 Saxo1tm1b(EUCOMM)Hmgu |
Hematology | Eosinophil differential count | homozygote | increased eosinophil cell number | 5.496959784068167E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 5.507819514605217E-5 | ||
Nol8 Nol8tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | increased startle reflex | 5.509112816071138E-5 | ||
Cav1 Cav1em2(IMPC)Ics |
Echo | HR | homozygote | increased heart rate | 5.531769056688063E-5 | ||
Prdm10 Prdm10tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | heterozygote | decreased bone mineral content | 5.561772923101671E-5 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Hematology | Hematocrit | homozygote | decreased hematocrit | 5.611987944575958E-5 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Triglycerides | homozygote | increased circulating triglyceride level | 5.6264289014507085E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Heart Weight | Tibia length | homozygote | short tibia | 5.631587919197045E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 5.6330238294322044E-5 | ||
Prrt2 Prrt2tm1b(KOMP)Wtsi |
Clinical Chemistry | Alkaline phosphatase | homozygote | decreased circulating alkaline phosphatase level | 5.63753601454664E-5 | ||
Cdh9 Cdh9tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 5.6529130233684555E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | BMC/Body weight | homozygote | decreased bone mineral content | 5.653870175592601E-5 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.6539000070188195E-5 | ||
Adipor1 Adipor1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 18kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 5.6539000070188195E-5 | ||
Cd276 Cd276tm2b(EUCOMM)Hmgu |
Open Field | Periphery resting time | homozygote | hyperactivity | 5.6932894949568436E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Open Field | Periphery average speed | hemizygote | hyperactivity | 5.803820022265427E-5 | ||
Gp6 Gp6tm2b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | long tibia | 5.8081197494175285E-5 | ||
Ncs1 Ncs1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb grip strength measurement mean | homozygote | decreased grip strength | 5.826607230119407E-5 | ||
Trpm6 Trpm6tm1b(KOMP)Wtsi |
Hematology | Mean cell volume | heterozygote | decreased mean corpuscular volume | 5.8288609579904005E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | NKT Cells (panel B) | heterozygote | increased NK T cell number | 5.853914626641199E-5 | ||
Gpr101 Gpr101tm1b(KOMP)Mbp |
Open Field | Center permanence time | hemizygote | decreased thigmotaxis | 5.865620187250897E-5 | ||
Gpr101 Gpr101tm1b(KOMP)Mbp |
Open Field | Percentage center time | hemizygote | abnormal behavior | 5.865620187250897E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Periphery permanence time | homozygote | increased thigmotaxis | 5.872579640708864E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Percentage center time | homozygote | abnormal behavior | 5.872579640708864E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Center permanence time | homozygote | increased thigmotaxis | 5.872579640708864E-5 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Tail - morphology | homozygote | abnormal tail morphology | 5.873131158296019E-5 | ||
Gpr101 Gpr101tm1b(KOMP)Mbp |
Open Field | Periphery permanence time | hemizygote | decreased thigmotaxis | 5.873394547961652E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Immunophenotyping | DN CD44+CD62L- NKT cells | heterozygote | increased memory-marker CD4-negative NK T cell number | 5.873933696420863E-5 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | decreased prepulse inhibition | 5.884501297259703E-5 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Context freezing total | homozygote | abnormal contextual conditioning behavior | 5.8979607274523005E-5 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | homozygote | decreased mean corpuscular volume | 5.938364483881742E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - back | homozygote | abnormal coat/ hair morphology | 5.960176349617541E-5 | ||
Ncs1 Ncs1tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 5.9659458202077076E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Open Field | Percentage center movement time | homozygote | increased anxiety-related response | 5.97341604589019E-5 | ||
Iah1 Iah1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - Global | homozygote | increased prepulse inhibition | 5.979651541565545E-5 | ||
Klf12 Klf12tm1b(EUCOMM)Wtsi |
Eye Morphology | Left inner nuclear layer | heterozygote | abnormal retina inner nuclear layer morphology | 5.9856538427993655E-5 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Eye Morphology | Retinal Blood Vessels | heterozygote | abnormal retina vasculature morphology | 5.997620246489532E-5 | ||
Gatad2b Gatad2btm1b(EUCOMM)Hmgu |
Open Field | Whole arena resting time | heterozygote | decreased locomotor activity | 6.005756222293712E-5 | ||
Plscr1 Plscr1tm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | homozygote | increased startle reflex | 6.016172483214177E-5 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Vocalization | heterozygote | abnormal vocalization | 6.0367292462615296E-5 | ||
Pcsk1 Pcsk1tm1b(EUCOMM)Wtsi |
Eye Morphology | Retinal Blood Vessels Pattern | heterozygote | abnormal retina blood vessel morphology | 6.050615411368199E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Open Field | Periphery distance travelled | homozygote | hyperactivity | 6.0701535403495654E-5 | ||
Tmprss2 Tmprss2tm2b(EUCOMM)Hmgu |
Echo | Fractional Shortening | homozygote | decreased cardiac muscle contractility | 6.080992170609534E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | Triglycerides | homozygote | decreased circulating triglyceride level | 6.097966979723424E-5 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 6.114081043051556E-5 | ||
Mocos Mocosem2(IMPC)Ics |
Clinical Chemistry | HDL-cholesterol | heterozygote | increased circulating HDL cholesterol level | 6.144158396637067E-5 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 6.146739178802818E-5 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat mass | heterozygote | increased total body fat amount | 6.186772952787578E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Clinical Chemistry | Total cholesterol | homozygote | decreased circulating cholesterol level | 6.197081529535353E-5 | ||
Atad2b Atad2btm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | hyperactivity | 6.202638178365305E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Whole arena average speed | homozygote | decreased locomotor activity | 6.249848229344934E-5 | ||
Klhl29 Klhl29tm1b(EUCOMM)Hmgu |
Echo | Fractional Shortening | homozygote | increased cardiac muscle contractility | 6.261807720875368E-5 | ||
Lca5l Lca5lem1(IMPC)Ics |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 6.291184399742633E-5 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Hematology | Hematocrit | homozygote | increased hematocrit | 6.304894486675039E-5 | ||
Lcp2 Lcp2tm1b(KOMP)Wtsi |
Eye Morphology | Lens | heterozygote | abnormal lens morphology | 6.318731902865693E-5 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration habituation-1 | heterozygote | abnormal locomotor behavior | 6.323367415461689E-5 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | decreased startle reflex | 6.323568231891841E-5 | ||
Nrp1 Nrp1tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 6.327198207145557E-5 | ||
Padi3 Padi3tm1b(KOMP)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 6.327198207145557E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Hematology | Neutrophil cell count | homozygote | increased neutrophil cell number | 6.342614506138489E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | increased grip strength | 6.352374475682154E-5 | ||
Ncs1 Ncs1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 6.365862645907328E-5 | ||
Krt8 Krt8tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | heterozygote | improved glucose tolerance | 6.366117304423824E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | decreased grip strength | 6.369144102791324E-5 | ||
Timm50 Timm50tm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 6.379943079082295E-5 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Open Field | Periphery distance travelled | homozygote | decreased locomotor activity | 6.397537799784914E-5 | ||
Cfap119 Cfap119tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | decreased locomotor activity | 6.420024874387309E-5 | ||
Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
Open Field | Periphery distance travelled | homozygote | hyperactivity | 6.462683086283505E-5 | ||
Cdk8 Cdk8tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration pre-cue-2 | heterozygote | abnormal freezing behavior | 6.555773870786652E-5 | ||
Dusp11 Dusp11tm1b(EUCOMM)Wtsi |
Eye Morphology | Corneal mineralization | homozygote | abnormal cornea morphology | 6.583507638424635E-5 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Eye Morphology | Vitreous | heterozygote | abnormal vitreous body morphology | 6.584291986655444E-5 | ||
Cd19 Cd19em2(IMPC)Ics |
Hematology | Monocyte cell count | homozygote | increased monocyte cell number | 6.589305849047378E-5 | ||
Iqce Iqcetm1b(EUCOMM)Hmgu |
X-ray | Tibia length | homozygote | short tibia | 6.592855788767338E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Immunophenotyping | CD24+ CD8 T cells | homozygote | immune system phenotype | 6.645872053923085E-5 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | heterozygote | decreased blood urea nitrogen level | 6.646328256465495E-5 | ||
Ctsd Ctsdtm1b(EUCOMM)Wtsi |
Hematology | Hematocrit | heterozygote | decreased hematocrit | 6.647062400588766E-5 | ||
Nxn Nxntm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration habituation-1 | heterozygote | abnormal locomotor behavior | 6.677986675640568E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | homozygote | decreased grip strength | 6.680808292003348E-5 | ||
Krt8 Krt8tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | heterozygote | improved glucose tolerance | 6.71053203404881E-5 | ||
Hrh4 Hrh4tm1b(EUCOMM)Hmgu |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 6.727696018060669E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left outer nuclear layer | homozygote | abnormal retina outer nuclear layer morphology | 6.756473158020526E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total protein | homozygote | decreased circulating total protein level | 6.77038260619156E-5 | ||
Cd19 Cd19em2(IMPC)Ics |
Hematology | Lymphocyte differential count | homozygote | decreased lymphocyte cell number | 6.782874697819352E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Hematology | Hematocrit | homozygote | decreased hematocrit | 6.832493818365037E-5 | ||
Snx29 Snx29tm1b(EUCOMM)Hmgu |
Echo | HR | homozygote | decreased heart rate | 6.833506631664932E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Open Field | Number of center entries | homozygote | decreased locomotor activity | 6.83419857523404E-5 | ||
Rbck1 Rbck1tm1b(EUCOMM)Hmgu |
Open Field | Number of center entries | heterozygote | hyperactivity | 6.856184336356819E-5 | ||
Lrrc3 Lrrc3tm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte cell count | homozygote | decreased lymphocyte cell number | 6.87696083332412E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration context-1 | homozygote | abnormal contextual conditioning behavior | 6.886947085149586E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Electrocardiogram (ECG) | QT | homozygote | shortened QT interval | 6.892361852806062E-5 | ||
Cldnd2 Cldnd2tm1b(EUCOMM)Hmgu |
Eye Morphology | Left corneal thickness | homozygote | increased cornea thickness | 6.899567233631387E-5 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Eye Morphology | Corneal ulcer | homozygote | cornea ulcer | 6.904005567776039E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | decreased prepulse inhibition | 6.932808173587546E-5 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Limb grasp | homozygote | limb grasping | 6.948360532987863E-5 | ||
Dusp11 Dusp11tm1b(EUCOMM)Wtsi |
Electrocardiogram (ECG) | QRS | homozygote | prolonged QRS complex duration | 6.958103767829016E-5 | ||
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | heterozygote | decreased total retina thickness | 6.96094284649007E-5 | ||
Rwdd3 Rwdd3tm1b(KOMP)Wtsi |
Grip Strength | Forelimb grip strength normalised against body weight | heterozygote | decreased grip strength | 6.966642831685022E-5 | ||
Synpo2 Synpo2tm1b(EUCOMM)Wtsi |
Electrocardiogram (ECG) | PR | heterozygote | prolonged PR interval | 6.967224180698395E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | homozygote | hyperactivity | 6.978354213060811E-5 | ||
Ptpra Ptpratm1b(EUCOMM)Hmgu |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 6.98599687893875E-5 | ||
Rab19 Rab19tm1b(EUCOMM)Hmgu |
Eye Morphology | Left corneal thickness | homozygote | increased cornea thickness | 6.987411325098947E-5 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | short tibia | 6.997204036451876E-5 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 7.017353345872834E-5 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - back | heterozygote | abnormal coat/hair pigmentation | 7.030265260254964E-5 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - back | homozygote | abnormal coat/hair pigmentation | 7.030265260254964E-5 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - abdomen | heterozygote | abnormal coat/hair pigmentation | 7.030265260254964E-5 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color - head | homozygote | abnormal coat/hair pigmentation | 7.030265260254964E-5 | ||
Dcp2 Dcp2tm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - head | heterozygote | abnormal coat/hair pigmentation | 7.030265260254964E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
Open Field | Number of rears - total | heterozygote | increased vertical activity | 7.088026904966682E-5 | ||
Exd1 Exd1tm1b(EUCOMM)Hmgu |
Heart Weight | Heart weight | homozygote | increased heart weight | 7.22105469321832E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Clinical Chemistry | Calcium | homozygote | decreased circulating calcium level | 7.242373249027878E-5 | ||
Ptdss1 Ptdss1tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) differential count | homozygote | decreased large unstained cell number | 7.245234155561775E-5 | ||
Phf8 Phf8tm1dIcs |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | hemizygote | improved glucose tolerance | 7.245798769872636E-5 | ||
Plekhg3 Plekhg3tm1b(EUCOMM)Hmgu |
Eye Morphology | Left anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 7.299032586161047E-5 | ||
Baiap2l2 Baiap2l2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Gait | homozygote | abnormal gait | 7.322654710151255E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Combined SHIRPA and Dysmorphology | Gait | homozygote | abnormal gait | 7.322654710151255E-5 | ||
Olig1 Olig1em2(IMPC)Ics |
Open Field | Distance travelled - total | homozygote | hyperactivity | 7.338894647546113E-5 | ||
Il18rap Il18raptm1b(KOMP)Wtsi |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 7.363212353084236E-5 | ||
Enpp4 Enpp4em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | homozygote | decreased bone mineral density | 7.36399888410233E-5 | ||
Fpr3 Fpr3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 7.365939381998032E-5 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Fat mass | homozygote | decreased total body fat amount | 7.367989019257948E-5 | ||
Pgam5 Pgam5tm1b(EUCOMM)Wtsi |
Clinical Chemistry | HDL-cholesterol | homozygote | decreased circulating HDL cholesterol level | 7.372056279564276E-5 | ||
Phf8 Phf8tm1dIcs |
Clinical Chemistry | HDL-cholesterol | hemizygote | increased circulating HDL cholesterol level | 7.3730327130761E-5 | ||
Bphl Bphltm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration pre-cue-2 | homozygote | abnormal freezing behavior | 7.374544657068327E-5 | ||
Lca5l Lca5lem1(IMPC)Ics |
Eye Morphology | Right total retinal thickness | homozygote | increased total retina thickness | 7.378172449534759E-5 | ||
Phf8 Phf8tm1dIcs |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 7.381735485978425E-5 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Red blood cell count | heterozygote | decreased erythrocyte cell number | 7.395678403554484E-5 | ||
Dgkk Dgkkem1(IMPC)Ics |
Fear Conditioning | % Freezing duration habituation-1 | hemizygote | abnormal locomotor behavior | 7.447073585353792E-5 | ||
Saxo1 Saxo1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right vitreous humor thickness | homozygote | abnormal vitreous body morphology | 7.515551260439679E-5 | ||
Maz Mazem1(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Locomotor activity | heterozygote | decreased exploration in new environment | 7.54422799218446E-5 | ||
Mx2 Mx2em1(IMPC)Ics |
Eye Morphology | Left inner nuclear layer | homozygote | abnormal retina inner nuclear layer morphology | 7.54485881770961E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Open Field | Number of center entries | homozygote | decreased locomotor activity | 7.576558709843084E-5 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI1 | homozygote | increased prepulse inhibition | 7.585744606330991E-5 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Open Field | Whole arena resting time | homozygote | decreased locomotor activity | 7.594541239086539E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Center distance travelled | homozygote | decreased locomotor activity | 7.649995677638799E-5 | ||
Dgkk Dgkkem1(IMPC)Ics |
Clinical Chemistry | HDL-cholesterol | hemizygote | increased circulating HDL cholesterol level | 7.76030428824015E-5 | ||
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 7.801272295182571E-5 | ||
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 7.803125481586903E-5 | ||
Arhgap24 Arhgap24tm1b(KOMP)Wtsi |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 7.844930223654956E-5 | ||
Sun1 Sun1tm1b(EUCOMM)Wtsi |
Clinical Chemistry | Phosphorus | homozygote | increased circulating phosphate level | 7.850059046177194E-5 | ||
Cfap119 Cfap119tm1b(EUCOMM)Hmgu |
Open Field | Number of rears - total | homozygote | decreased vertical activity | 7.850596739444882E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Percentage center movement time | homozygote | increased anxiety-related response | 7.898405601736158E-5 | ||
Dnal4 Dnal4tm1b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Tremor | heterozygote | tremors | 7.931794243631884E-5 | ||
Ackr3 Ackr3tm2b(EUCOMM)Wtsi |
Combined SHIRPA and Dysmorphology | Tremor | heterozygote | tremors | 7.931794243631884E-5 | ||
Ahsa2 Ahsa2tm1b(EUCOMM)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 7.942496449686587E-5 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Eye Morphology | Cornea | homozygote | abnormal cornea morphology | 7.955614273669198E-5 | ||
Elapor1 Elapor1tm1b(EUCOMM)Hmgu |
Hematology | Lymphocyte cell count | heterozygote | decreased lymphocyte cell number | 7.961881783558056E-5 | ||
Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
Open Field | Center distance travelled | homozygote | decreased locomotor activity | 7.968868885654956E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Hematology | Red blood cell count | homozygote | decreased erythrocyte cell number | 7.980723603395745E-5 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Open Field | Number of rears - total | homozygote | decreased vertical activity | 7.981539965840057E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Body length | homozygote | decreased body length | 8.00607303972356E-5 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Eye Morphology | Right anterior chamber depth | homozygote | abnormal eye anterior chamber depth | 8.060887194005772E-5 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Open Field | Number of center entries | heterozygote | decreased locomotor activity | 8.077366510406137E-5 | ||
Mbd5 Mbd5tm1b(EUCOMM)Wtsi |
Open Field | Center distance travelled | heterozygote | decreased locomotor activity | 8.077873644651845E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Number of center entries | homozygote | decreased locomotor activity | 8.11111822258681E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Body Composition (DEXA lean/fat) | Bone Mineral Density (excluding skull) | hemizygote | decreased bone mineral density | 8.130865899147466E-5 | ||
Dnm1l Dnm1ltm1b(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - hair distribution - head | heterozygote | abnormal coat/ hair morphology | 8.159638673532754E-5 | ||
Hmgn1 Hmgn1em1(IMPC)Ics |
Clinical Chemistry | Creatinine | homozygote | decreased circulating creatinine level | 8.204314508475363E-5 | ||
Gpr101 Gpr101tm1b(KOMP)Mbp |
Open Field | Percentage center movement time | hemizygote | decreased anxiety-related response | 8.236259600380436E-5 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Heart Weight | Tibia length | homozygote | short tibia | 8.263520430773497E-5 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Clinical Chemistry | Creatinine | homozygote | increased circulating creatinine level | 8.275451546069235E-5 | ||
Dcaf7 Dcaf7tm1b(EUCOMM)Wtsi |
Eye Morphology | Right inner nuclear layer | heterozygote | abnormal retina inner nuclear layer morphology | 8.278941095340997E-5 | ||
Ncam2 Ncam2tm1b(EUCOMM)Hmgu |
Echo | LVIDs | homozygote | dilated heart left ventricle | 8.284815703518689E-5 | ||
Elk3 Elk3em1(IMPC)Ics |
Clinical Chemistry | HDL-cholesterol | heterozygote | increased circulating HDL cholesterol level | 8.298402826767415E-5 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Eye Morphology | Left total retinal thickness | homozygote | decreased total retina thickness | 8.300253830384463E-5 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Open Field | Distance travelled - total | homozygote | decreased locomotor activity | 8.304926450364292E-5 | ||
Cav1 Cav1em2(IMPC)Ics |
Hematology | Mean corpuscular hemoglobin | homozygote | increased mean corpuscular hemoglobin | 8.307708776555955E-5 | ||
Dbn1 Dbn1tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 8.340628119185567E-5 | ||
Bahd1 Bahd1tm2b(KOMP)Wtsi |
Open Field | Number of center entries | heterozygote | decreased locomotor activity | 8.398743375437334E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | homozygote | impaired glucose tolerance | 8.410305599682033E-5 | ||
Mocos Mocosem2(IMPC)Ics |
Clinical Chemistry | Total cholesterol | heterozygote | increased circulating cholesterol level | 8.411757153226063E-5 | ||
Cdc26 Cdc26tm1b(EUCOMM)Hmgu |
Echo | Fractional Shortening | heterozygote | increased cardiac muscle contractility | 8.43682573758997E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Clinical Chemistry | Glucose | homozygote | increased circulating glucose level | 8.45982285682112E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Clinical Chemistry | Creatinine | homozygote | decreased circulating creatinine level | 8.46425537019968E-5 | ||
Rnf144b Rnf144btm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 8.499732939526439E-5 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Hematology | Mean cell volume | heterozygote | increased mean corpuscular volume | 8.504481957061216E-5 | ||
Yipf5 Yipf5tm1b(EUCOMM)Hmgu |
Hematology | Red blood cell count | heterozygote | decreased erythrocyte cell number | 8.56477054185234E-5 | ||
Prkab1 Prkab1tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | homozygote | decreased grip strength | 8.579831046517938E-5 | ||
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 8.602344314567745E-5 | ||
Snx29 Snx29tm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 8.602344314567745E-5 | ||
Ppp6c Ppp6ctm1b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 6kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 8.602344314567745E-5 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 8.705400978215039E-5 | ||
Cav1 Cav1em2(IMPC)Ics |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 8.713949500815943E-5 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QRS | homozygote | shortened QRS complex duration | 8.74812831170857E-5 | ||
Mocos Mocosem2(IMPC)Ics |
Body Composition (DEXA lean/fat) | Fat mass | heterozygote | increased total body fat amount | 8.750153938308358E-5 | ||
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
Clinical Chemistry | Calcium | homozygote | increased circulating calcium level | 8.754977898206562E-5 | ||
Cd276 Cd276tm2b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 8.831056038616225E-5 | ||
Laptm4a Laptm4atm1b(EUCOMM)Hmgu |
Acoustic Startle and Pre-pulse Inhibition (PPI) | % Pre-pulse inhibition - PPI4 | homozygote | increased prepulse inhibition | 8.837931090965867E-5 | ||
Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi |
Eye Morphology | Optic Disc | homozygote | abnormal optic disk morphology | 8.841968519845977E-5 | ||
Dnm1l Dnm1ltm1b(KOMP)Wtsi |
Eye Morphology | Optic Disc | heterozygote | abnormal optic disk morphology | 8.841968519845977E-5 | ||
Tmem108 Tmem108tm1b(EUCOMM)Wtsi |
Body Composition (DEXA lean/fat) | Bone Mineral Content (excluding skull) | homozygote | increased bone mineral content | 8.849360165186226E-5 | ||
Cbr3 Cbr3em1(IMPC)Ics |
Combined SHIRPA and Dysmorphology | Locomotor activity | homozygote | decreased exploration in new environment | 8.882016118150204E-5 | ||
App Apptm1b(KOMP)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 8.88733848114498E-5 | ||
Cstb Cstbtm1b(EUCOMM)Wtsi |
Clinical Chemistry | Triglycerides | homozygote | increased circulating triglyceride level | 8.890672324923798E-5 | ||
Kif5c Kif5ctm1dIcs |
Clinical Chemistry | Total protein | heterozygote | increased circulating total protein level | 8.911915210774168E-5 | ||
Rspo1 Rspo1tm2b(KOMP)Wtsi |
Body Composition (DEXA lean/fat) | Lean/Body weight | homozygote | decreased lean body mass | 8.94394688657485E-5 | ||
Rasal3 Rasal3tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Triglycerides | homozygote | increased circulating triglyceride level | 8.968274050857872E-5 | ||
Epx Epxtm1b(EUCOMM)Wtsi |
Hematology | Monocyte differential count | homozygote | increased monocyte cell number | 8.973132207756862E-5 | ||
Knstrn Knstrntm1b(KOMP)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Fasted blood glucose concentration | homozygote | increased fasting circulating glucose level | 8.996929682325572E-5 | ||
Pdlim4 Pdlim4em1(IMPC)Ics |
Clinical Chemistry | Glucose | homozygote | decreased circulating glucose level | 8.998357225209475E-5 | ||
Atxn7l3 Atxn7l3tm1.1(KOMP)Wtsi |
Combined SHIRPA and Dysmorphology | Coat - color pattern - abdomen | heterozygote | abnormal coat/hair pigmentation | 9.018691343953833E-5 | ||
4933430I17Rik 4933430I17Riktm1a(EUCOMM)Wtsi |
Hematology | Mean cell volume | homozygote | increased mean corpuscular volume | 9.037653944687918E-5 | ||
Dyrk1b Dyrk1btm1b(EUCOMM)Wtsi |
Hematology | Lymphocyte cell count | heterozygote | decreased lymphocyte cell number | 9.118910384131595E-5 | ||
Ppp4c Ppp4cem1(IMPC)Ics |
Fear Conditioning | % Freezing duration context-3 | heterozygote | abnormal contextual conditioning behavior | 9.11936440388672E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | increased startle reflex | 9.122952178586274E-5 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Electrocardiogram (ECG) | QT | homozygote | prolonged QT interval | 9.12912655621767E-5 | ||
Cdc27 Cdc27tm1dIcs |
Body Composition (DEXA lean/fat) | Lean/Body weight | heterozygote | decreased lean body mass | 9.206594404531643E-5 | ||
Med25 Med25tm1b(KOMP)Wtsi |
Eye Morphology | Right total retinal thickness | heterozygote | decreased total retina thickness | 9.219841012964025E-5 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Open Field | Center resting time | homozygote | decreased locomotor activity | 9.255113400286064E-5 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Hematology | White blood cell count | homozygote | decreased leukocyte cell number | 9.292658069171011E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength measurement mean | heterozygote | decreased grip strength | 9.312970360042527E-5 | ||
Cdh13 Cdh13tm1b(EUCOMM)Hmgu |
Open Field | Center average speed | homozygote | hyperactivity | 9.329611202701926E-5 | ||
Eftud2 Eftud2tm1b(KOMP)Wtsi |
Grip Strength | Forelimb and hindlimb grip strength normalised against body weight | heterozygote | decreased grip strength | 9.331661567557603E-5 | ||
Il2ra Il2ratm1b(EUCOMM)Wtsi |
Fear Conditioning | % Freezing duration habituation-2 | homozygote | abnormal locomotor behavior | 9.36173673835583E-5 | ||
Morc3 Morc3tm1b(EUCOMM)Hmgu |
Hematology | Hematocrit | heterozygote | decreased hematocrit | 9.388236503582448E-5 | ||
Rnf10 Rnf10tm1b(KOMP)Wtsi |
Intraperitoneal glucose tolerance test (IPGTT) | Area under glucose response curve | homozygote | improved glucose tolerance | 9.412713552592322E-5 | ||
Lca5l Lca5lem1(IMPC)Ics |
Hematology | Hemoglobin | homozygote | decreased hemoglobin content | 9.420527931069955E-5 | ||
Cidea Cideatm1b(EUCOMM)Hmgu |
Clinical Chemistry | Albumin | homozygote | increased circulating serum albumin level | 9.43153427215293E-5 | ||
Mir124a-2 Mir124a-2tm1b(mirKO)Wtsi |
Fear Conditioning | % Freezing duration context-2 | heterozygote | abnormal contextual conditioning behavior | 9.442286682315171E-5 | ||
Taf2 Taf2tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Cholesterol ratio | heterozygote | abnormal cholesterol homeostasis | 9.504217450739816E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Persistence of hyaloid vascular system | homozygote | persistence of hyaloid vascular system | 9.51105248532258E-5 | ||
Bscl2 Bscl2tm1b(EUCOMM)Hmgu |
Intraperitoneal glucose tolerance test (IPGTT) | Initial response to glucose challenge | homozygote | improved glucose tolerance | 9.52101981965825E-5 | ||
Ankrd11 Ankrd11tm1b(EUCOMM)Wtsi |
Acoustic Startle and Pre-pulse Inhibition (PPI) | Response amplitude - S | heterozygote | decreased startle reflex | 9.557861631037667E-5 | ||
Fam3b Fam3btm1b(EUCOMM)Hmgu |
Open Field | Latency to center entry | homozygote | decreased exploration in new environment | 9.58599557634443E-5 | ||
Pdpr Pdprtm1b(EUCOMM)Wtsi |
Clinical Chemistry | Cholesterol ratio | homozygote | abnormal cholesterol homeostasis | 9.589349065208808E-5 | ||
Lca5l Lca5lem1(IMPC)Ics |
Hematology | Hematocrit | homozygote | decreased hematocrit | 9.595209849067032E-5 | ||
Kcne1 Kcne1tm1b(EUCOMM)Hmgu |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | increased lean body mass | 9.616309398552403E-5 | ||
Aak1 Aak1tm1b(EUCOMM)Hmgu |
Fear Conditioning | % Freezing duration context-2 | homozygote | abnormal contextual conditioning behavior | 9.620055789127946E-5 | ||
Thra Thratm1b(EUCOMM)Wtsi |
X-ray | Tibia length | heterozygote | short tibia | 9.620228229323402E-5 | ||
Nab2 Nab2tm1b(EUCOMM)Hmgu |
Open Field | Percentage center movement time | homozygote | increased anxiety-related response | 9.622697689337656E-5 | ||
Ecrg4 Ecrg4tm1b(EUCOMM)Hmgu |
Hematology | Large Unstained Cell (LUC) count | homozygote | decreased large unstained cell number | 9.632152068661526E-5 | ||
Setx Setxtm1b(EUCOMM)Wtsi |
Eye Morphology | Right total retinal thickness | homozygote | decreased total retina thickness | 9.676147601567209E-5 | ||
Parp1 Parp1tm1b(EUCOMM)Hmgu |
Immunophenotyping | NK cells (panel A) | homozygote | decreased NK cell number | 9.684113319963217E-5 | ||
Hmgn1 Hmgn1em1(IMPC)Ics |
Body Composition (DEXA lean/fat) | Lean mass | homozygote | decreased lean body mass | 9.70390610746108E-5 | ||
Dbnl Dbnltm1b(KOMP)Wtsi |
Eye Morphology | Left inner nuclear layer | homozygote | abnormal retina inner nuclear layer morphology | 9.716184285935014E-5 | ||
Snx29 Snx29tm1b(EUCOMM)Hmgu |
Indirect Calorimetry | Total food intake | homozygote | decreased food intake | 9.732945181895047E-5 | ||
Ptchd1 Ptchd1tm1b(KOMP)IcsOrl |
Body Composition (DEXA lean/fat) | Lean mass | hemizygote | increased lean body mass | 9.777098603080958E-5 | ||
Scaper Scapertm1b(EUCOMM)Hmgu |
Clinical Chemistry | Urea (Blood Urea Nitrogen - BUN) | homozygote | decreased blood urea nitrogen level | 9.83113786787726E-5 | ||
Ddr1 Ddr1tm1b(EUCOMM)Hmgu |
Open Field | Whole arena average speed | heterozygote | hyperactivity | 9.89399995887652E-5 | ||
Otub1 Otub1tm1b(EUCOMM)Hmgu |
Eye Morphology | Left corneal thickness | heterozygote | increased cornea thickness | 9.894355753203854E-5 | ||
Tiam1 Tiam1tm1b(EUCOMM)Hmgu |
Eye Morphology | Right corneal thickness | homozygote | increased cornea thickness | 9.958538430510089E-5 | ||
Padi3 Padi3tm1b(KOMP)Wtsi |
Clinical Chemistry | HDL-cholesterol | homozygote | increased circulating HDL cholesterol level | 9.97518072836101E-5 | ||
Ntf5 Ntf5tm1b(EUCOMM)Hmgu |
Clinical Chemistry | Total protein | homozygote | increased circulating total protein level | 9.982840128941461E-5 | ||
Obp2a Obp2atm1b(EUCOMM)Wtsi |
Clinical Chemistry | Total cholesterol | homozygote | increased circulating cholesterol level | 9.991669503506273E-5 | ||
Gp6 Gp6tm2b(EUCOMM)Hmgu |
Auditory Brain Stem Response | 12kHz-evoked ABR Threshold | homozygote | abnormal auditory brainstem response | 2.4359601957257837E-4 | ||
Myo18b Myo18bem2(IMPC)Ics |
Auditory Brain Stem Response | 30kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 0.0021858587861061096 | ||
Phf6 Phf6tm1b(EUCOMM)Wtsi |
Auditory Brain Stem Response | 24kHz-evoked ABR Threshold | heterozygote | abnormal auditory brainstem response | 0.06902985274791718 |