Gene: Dagla

Order

Name diacylglycerol lipase, alpha

Synonyms Nsddr

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2677061    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Dagla

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dagla data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased brain size Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
small heart Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
small liver Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
small lung Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
small spleen Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
small stomach Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
small thymus Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 0.0
abnormal bone structure Daglatm1a(EUCOMM)Wtsi HOM Female Male postnatal 6.31E-11
decreased bone mineral content Daglatm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.48E-10
decreased lean body mass Daglatm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.85E-9
decreased bone mineral density Daglatm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.2E-8
decreased body length Daglatm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.94E-7
improved glucose tolerance Daglatm1a(EUCOMM)Wtsi HOM Male postnatal 5.57E-6
abnormal behavior Daglatm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.79E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Phenotype associated images not available

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Daglatm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Daglatm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Daglatm40176(L1L2_gt0)
Vector
Gene